scholarly journals Utility of Contrast-Enhanced Transabdominal Ultrasonography to Diagnose Early Chronic Pancreatitis

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Nobuaki Azemoto ◽  
Teru Kumagi ◽  
Tomoyuki Yokota ◽  
Masashi Hirooka ◽  
Taira Kuroda ◽  
...  
Keyword(s):  
Blood Flow ◽  
Chronic Pancreatitis ◽  
Mesenteric Artery ◽  
Region Of Interest ◽  
Pancreatic Blood Flow ◽  
Transabdominal Ultrasonography ◽  
Pancreatic Parenchyma ◽  
Contrast Enhanced ◽  
And Control ◽  
The Relationship

Purpose. The purpose of this study was to establish the relationship between the grade of chronic pancreatitis (CP) and pancreatic blood flow as measured by contrast-enhanced transabdominal ultrasonography (CEUS) and to diagnose early CP easily.Methods. This pilot study was conducted in 8 patients with CP, 7 patients with early CP, and 6 control participants. After injecting 0.015 mL/kg of perflubutane by manual bolus, values in one region of interest (ROI) in pancreatic parenchyma and one ROI including the superior mesenteric artery (SMA) were measured.Results. The ratio of blood flow in the SMA and pancreatic parenchyma increased with grade of CP and was significantly higher in patients with CP (5.41; 2.10–11.02) than in patients with early CP (2.46; 1.41–5.05) and control participants (2.32; 1.25–3.04)(P=0.0279,P=0.0142, resp.). The ratio of blood flow in the SMA and pancreatic parenchyma correlated with grade of CP(rs=0.5904,P=0.0048).Conclusion. The ratio of blood flow correlates with grade of CP on CEUS. This safe and convenient method may be useful to diagnose early CP.

scholarly journals Effect of inguinal hernia on the thickness and blood flow of spermatic cord in boys

2019 ◽  
Vol 2 (2) ◽  
pp. e000030
Author(s):  
Shoujiang Huang ◽  
Canping Li ◽  
Xiuzhen Yang ◽  
Jianfeng Liang ◽  
Dongpi Wang
Keyword(s):  
Blood Flow ◽  
Inguinal Hernia ◽  
Spermatic Cord ◽  
Peak Systolic Velocity ◽  
Control Group ◽  
Pampiniform Plexus ◽  
Significant Difference ◽  
Highly Correlated ◽  
And Control ◽  
The Relationship

ObjectiveTo evaluate the effect of inguinal hernia (IH) on the spermatic cord using spermatic cord ultrasonography (SCU).MethodsFrom January 2016 to January 2017, boys with IH who received SCU at the start of open herniorrhaphy (OH) were enrolled in this study. The age and weight at SCU, width of the spermatic cord (SC-W), peak systolic velocity (PSV) in the spermatic artery (SA-PSV) and velocity in the pampiniform plexus (PP-V), and the interval between the initial and the second OH in boys with metachronous inguinal hernia (MIH) were recorded, and the relationship among them was studied. Boys with unilateral IH comprised the IH group, and boys with MIH comprised the MIH group. Boys with polydactylism served as the control. One-way analysis of variance tested the differences among groups. Spearman’s r tested the relationship between SC-W in the MIH group and the interval.ResultsA total of 80 boys were enrolled in this study (IH group 29, MIH group 26, and control group 25). SA-PSV and PP-V in the hernia side were faster and slower than the control, respectively. There was no significant difference in PP-V and SA-PSV of the treated side in the MIH group and in the control group. After herniorrhaphy, SC-W was tapered down to normal size. SC-W, SA-PSV, and PP-V in the treated side were all highly correlated to the interval in a curvilinear manner.ConclusionPSV was positively correlated with SC-W in boys with IH, and PP-V was negatively correlated; herniorrhaphy could reverse the impairment.

scholarly journals Effect of Pancreaticojejunostomy on Fibrosis, Pancreatic Blood Flow, and Interstitial pH in Chronic Pancreatitis

1999 ◽  
Vol 230 (5) ◽  
pp. 672 ◽  
Author(s):  
Ameet G. Patel ◽  
Peter U. Reber ◽  
Mark T. Toyama ◽  
Stanley W. Ashley ◽  
Howard A. Reber
Keyword(s):  
Blood Flow ◽  
Chronic Pancreatitis ◽  
Pancreatic Blood Flow

Pancreatic blood flow in cats with chronic pancreatitis

1992 ◽  
Vol 103 (2) ◽  
pp. 652-659 ◽  
Author(s):  
Howard A. Reber ◽  
Nariman D. Karanjia ◽  
Carlos Alvarez ◽  
Adam L. Widdison ◽  
Felix W. Leung ◽  
...  
Keyword(s):  
Blood Flow ◽  
Chronic Pancreatitis ◽  
Pancreatic Blood Flow

Role of nitric oxide in the relationship of pancreatic blood flow and exocrine secretion in cats

1995 ◽  
Vol 108 (4) ◽  
pp. 1215-1220 ◽  
Author(s):  
Ameet G. Patel ◽  
Mark T. Toyama ◽  
Thanh N. Nguyen ◽  
Gordon A. Cohen ◽  
Louis J. Ignarro ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Blood Flow ◽  
Exocrine Secretion ◽  
Pancreatic Blood Flow ◽  
Relationship Of ◽  
The Relationship

Role of prostaglandins and nitric oxide in gastrointestinal hyperemia of diabetic rats

1996 ◽  
Vol 270 (4) ◽  
pp. G684-G690 ◽  
Author(s):  
E. Goldin ◽  
M. Casadevall ◽  
M. Mourelle ◽  
I. Cirera ◽  
J. I. Elizalde ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Blood Flow ◽  
Gastric Mucosa ◽  
Superior Mesenteric Artery ◽  
Mesenteric Artery ◽  
Left Gastric Artery ◽  
Diabetic Rats ◽  
Gastric Artery ◽  
Blood Flows ◽  
And Control

The aim of the study was to characterize the gastric and mesenteric vascular changes induced by diabetes and the implication of endothelial [nitric oxide (NO) and prostaglandins] and humoral (glucagon) factors in such changes. Diabetes was induced in rats by a single streptozotocin injection. Four weeks later, gastric mucosa, left gastric artery, and superior mesenteric artery blood flows were measured using hydrogen gas clearance and perivascular ultrasonic flowmeter techniques, respectively, in anesthetized and fasted diabetic and control rats. Blood pressure, hematocrit, blood volume, and blood viscosity were also measured. Left gastric (41 +/- 6 vs. 25 +/- 4 ml.min-1.100 g-1) and superior mesenteric artery blood flows (83 +/- 8 vs. 65 +/- 4 ml.min-1.100 g-1) were significantly higher in diabetic than in control rats. The increased blood flow in the left gastric artery was distributed to a hypertrophic mucosa in diabetic rats; therefore, the blood flow per 100 g tissue in the gastric mucosa was not significantly different in diabetic compared with control rats. Pretreatment with indomethacin reduced both increase gastric and mesenteric flows of the diabetic rats to the same levels as in control rats. NG-nitro-L-arginine methyl ester decreased gastric blood flow in a dose-dependent manner and to a similar extent in diabetic and control rats. In contrast, an increased sensitivity to the higher doses of the NO inhibitor was observed in the mesenteric vascular bed of diabetic rats. Glucagon reduction achieved by somatostatin infusion did not influence either gastric or mesenteric blood flow in diabetic rats. In summary, the present study revealed an increase in gastric and mesenteric arterial blood flows in streptozotocin-induced diabetic rats. The gastrointestinal hyperemia seems to be due, at least in part, to the increased demand of a hypertrophic mucosa and is mediated primarily by endogenous prostaglandins. Increased vascular sensitivity to NO may also contribute to the mesenteric vasodilation.

Relationship of blood flow to pressure in the intestinal vascular bed of the dog

1962 ◽  
Vol 202 (2) ◽  
pp. 253-256 ◽  
Author(s):  
E. Clinton Texter ◽  
Steven Merrill ◽  
Melvin Schwartz ◽  
Guido Van Derstappen ◽  
Francis J. Haddy
Keyword(s):  
Blood Flow ◽  
Superior Mesenteric Artery ◽  
Mesenteric Artery ◽  
Vascular Bed ◽  
Local Mechanism ◽  
Small Vein ◽  
Flow Through ◽  
Renal Vascular ◽  
Relationship Of ◽  
The Relationship

The relationship of pressure in the superior mesenteric artery, mesenteric small artery, mesenteric small vein, and portal vein to the rate of blood flow in the superior mesenteric artery was studied in eight dogs. Total bed resistance to blood flow decreased as a function of flow over the range 20–60 ml/min but increased as a function of flow over the range 90–270 ml/min. The onset and cessation of the resistance increase were associated with pressures in the superior mesenteric artery of 64 and 205 mm Hg, respectively. These resistance changes resulted mainly from change of resistance to flow through vessels less than 0.5 mm diameter. The findings suggest that the intestinal vascular bed, like the renal vascular bed, has a local mechanism which antagonizes changes of flow rate produced by variation of arterial pressure.

Ventilatory threshold is related to walking tolerance in patients with intermittent claudication

VASA ◽  
2012 ◽  
Vol 41 (4) ◽  
pp. 275-281 ◽  
Author(s):  
da Rocha Chehuen ◽  
G. Cucato ◽  
P. dos Anjos Souza Barbosa ◽  
A. R. Costa ◽  
M. Ritti-Dias ◽  
...  
Keyword(s):  
Blood Flow ◽  
Oxygen Uptake ◽  
Intermittent Claudication ◽  
Lower Limb ◽  
Ventilatory Threshold ◽  
Reactive Hyperemia ◽  
Ankle Brachial Index ◽  
Metabolic Parameters ◽  
Walking Distance ◽  
The Relationship

Background: This study assessed the relationship between lower limb hemodynamics and metabolic parameters with walking tolerance in patients with intermittent claudication (IC). Patients and methods: Resting ankle-brachial index (ABI), baseline blood flow (BF), BF response to reactive hyperemia (BFRH), oxygen uptake (VO2), initial claudication distance (ICD) and total walking distance (TWD) were measured in 28 IC patients. Pearson and Spearman correlations were calculated. Results: ABI, baseline BF and BF response to RH did not correlate with ICD or TWD. VO2 at first ventilatory threshold and VO2peak were significantly and positively correlated with ICD (r = 0.41 and 0.54, respectively) and TWD (r = 0.65 and 0.71, respectively). Conclusions: VO2peak and VO2 at first ventilatory threshold, but not ABI, baseline BF and BFHR were associated with walking tolerance in IC patients. These results suggest that VO2 at first ventilatory threshold may be useful to evaluate walking tolerance and improvements in IC patients.

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