scholarly journals Cardiopulmonary Response to Exercise in COPD and Overweight Patients: Relationship between Unloaded Cycling and Maximal Oxygen Uptake Profiles

2015 ◽  
Vol 2015 ◽  
pp. 1-7
Author(s):  
Abdoulaye Ba ◽  
Fabienne Brégeon ◽  
Stéphane Delliaux ◽  
Fallou Cissé ◽  
Abdoulaye Samb ◽  
...  
Keyword(s):  
Oxygen Uptake ◽  
Maximal Oxygen Uptake ◽  
Ventilatory Threshold ◽  
Minute Ventilation ◽  
Rehabilitation Program ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Exercise Rehabilitation ◽  
Copd Patients ◽  
Overweight Subjects

Cardiopulmonary response to unloaded cycling may be related to higher workloads. This was assessed in male subjects: 18 healthy sedentary subjects (controls), 14 hypoxemic patients with chronic obstructive pulmonary disease (COPD), and 31 overweight individuals (twelve were hypoxemic). They underwent an incremental exercise up to the maximal oxygen uptake (VO2max), preceded by a 2 min unloaded cycling period. Oxygen uptake (VO2), heart rate (HR), minute ventilation (VE), and respiratory frequency (fR) were averaged every 10 s. At the end of unloaded cycling period, HR increase was significantly accentuated in COPD and hypoxemic overweight subjects (resp.,+14±2and+13±1.5 min−1, compared to+7.5±1.5 min−1in normoxemic overweight subjects and+8±1.8 min−1in controls). The fR increase was accentuated in all overweight subjects (hypoxemic:+4.5±0.8; normoxemic:+3.9±0.7 min−1) compared to controls (+2.5±0.8 min−1) and COPDs (+2.0±0.7 min−1). The plateau VE increase during unloaded cycling was positively correlated with VE values measured at the ventilatory threshold and VO2max. Measurement of ventilation during unloaded cycling may serve to predict the ventilatory performance of COPD patients and overweight subjects during an exercise rehabilitation program.

Intercept of minute ventilation vs. carbon dioxide output relationship in chronic obstructive pulmonary disease: utility as an index of ventilatory inefficiency

2020 ◽  
Author(s):  
Haoyan Wang ◽  
Fang Lin ◽  
Shan Nie ◽  
Ranran Zhao ◽  
Min Cao ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Minute Ventilation ◽  
Airflow Limitation ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Lung Hyperinflation ◽  
Carbon Dioxide Output ◽  
Copd Patients

Abstract Background: Ventilatory inefficiency is known to be a contributor to exercise intolerance in chronic obstructive pulmonary disease (COPD). The intercept of the minute ventilation (V̇E) vs. carbon dioxide output (V̇CO2) plot is a key ventilator inefficiency parameter. However, its relationships with lung hyperinflation (LH) and airflow limitation are not known. This study aimed to evaluate the correlations between the V̇E/V̇CO2 intercept and LH in COPD to determine its utility as an index of functional impairment.Methods: We conducted a retrospective analysis of data from 53 COPD patients and 14 healthy controls performed incremental cardiopulmonary exercise tests and resting pulmonary function. Ventilatory inefficiency was represented by parameters reflecting the V̇E/V̇CO2 nadir and slope (linear region), and intercept of the V̇E/V̇CO2 plot. Their correlations with measures of LH and airflow limitation were evaluated.Results: Compared to the control, the slope (30.58±3.62) and intercept (4.85±1.11) higher in COPDstages1-2, leading to a higher nadir (31.47±4.47) (p<0.05). Despite an even higher intercept in COPDstages3-4 (7.16±1.41), the slope diminished with disease progression (from 30.58±3.62 in COPDstages1-2 to 28.36±4.58 in COPDstages3-4). Compared to the V̇E/V̇CO2 nadir and V̇E/V̇CO2 slope, the intercept was better correlated with peak V̇E/maximal voluntary ventilation (MVV) (r=0.489, p<0.001) and peak V̇O2/watt (r=0.354, p=0.003). The intercept was also significantly correlated with RV/TLC (r=0.588, p<0.001), IC/TLC (r=-0.574, p<0.001), peak VT/TLC (r=-0.585, p<0.001); and airflow limitation forced expiratory volume in 1s (FEV1) % predicted (r=-0.606, p<0.001) and FEV1/forced vital capacity (FVC) (r=-0.629, p<0.001).Conclusion: V̇E/V̇CO2intercept was consistently better correlated with worsening static and dynamic lung hyperinflation and airflow limitation in COPD. V̇E/V̇CO2 intercept emerged as a useful index of ventilatory inefficiency across the severity spectrum of COPD patients.

scholarly journals Respiratory pattern, thoracoabdominal motion and ventilation in chronic airway obstruction

2016 ◽  
Vol 67 (4) ◽  
Author(s):  
M. Fernandes ◽  
A. Cukier ◽  
N. Ambrosino ◽  
J.J. Leite ◽  
M.I. Zanetti Feltrim
Keyword(s):  
Breathing Pattern ◽  
Minute Ventilation ◽  
Respiratory Pattern ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Copd Patients ◽  
Lower Oxygen ◽  
Shallow Breathing ◽  
Diaphragmatic Movement ◽  
Severe Copd

Background. Patients with chronic obstructive pulmonary disease (COPD) present abnormal respiratory mechanics, but its relation to ventilation variables at rest is not fully understood. Methods. We evaluated breathing pattern, thoracoabdominal motion, and ventilation in moderate and severe COPD patients by means of respiratory inductive plethysmograph and analysis of respiratory metabolism in semirecumbent position at rest. Diaphragmatic movement was measured using radiographs. Results. COPD patients showed an increase in mean inspiratory flow, minute ventilation, dead space ventilation, oxygen and carbon dioxide ventilatory equivalents and reduction of respiratory times and pulse oxymetry. These findings were more pronounced in severe COPD. Changes in ventilatory efficiency were correlated with decreased respiratory times, reduced diaphragmatic movement, and lower oxygen uptake. Conclusions. Rapid shallow breathing and reduced diaphragmatic movement have led to ventilatory inefficiency without changes in thoracoabdominal motion.

Effects of laundry-hanging motion on oxygen uptake and ventilation in healthy young women

2020 ◽  
Vol 16 (5) ◽  
pp. 367-370
Author(s):  
M. Takahata ◽  
M. Ishizawa ◽  
T. Uchiumi ◽  
M. Yamaki ◽  
T. Sato
Keyword(s):  
Oxygen Uptake ◽  
Minute Ventilation ◽  
Standing Position ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Metabolic Equivalents ◽  
Different Types ◽  
Reduced Physical Activity ◽  
Mutual Comparison ◽  
Healthy Females

Many patients with chronic obstructive pulmonary disease (COPD) experience problems during performance of activities of daily living. These problems may lead to reduced physical activity. The purpose of this study was to reveal the influence on the oxygen uptakes in motion methods of hanging on laundry. Eighteen healthy females were recruited for participation in this study. They performed three kinds of movement to hang on laundry. Participants performed the following three actions: (1) hanging some towels on bars with a low stand in a sitting position (Action 1), (2) hanging some towels on bars with a low stand in a standing position (Action 2) and (3) hanging some towels on bars with a high stand in a standing position (Action 3). We measured metabolic and ventilatory requirements during these actions by use of an expires gas analyser. Mutual comparison of the three different types action showed significant differences in the oxygen uptake (VO2), carbon dioxide output (VCO2), minute ventilation (VE), and metabolic equivalents (METs). On the other hands, the differences in respiratory rate (RR) among these three actions were not significant. Action 3 tended to have the most increased values in VO2, VCO2, VE and METs. The Action 1 tended to behave the lowest value. The oxygen uptake and ventilation variables may be influenced by the methods used in hanging laundry.

scholarly journals Respiratory rehabilitation techniques used for the treatment of COPD patients

2020 ◽  
Vol 11 (Vol.11, no.3) ◽  
pp. 269-273
Author(s):  
Georgeta PATRASCA ◽  
Gilda POPESCU ◽  
Doina Ecaterina TOFOLEAN ◽  
Anca MAIEREAN ◽  
Gabriela DOGARU ◽  
...  
Keyword(s):  
Exercise Tolerance ◽  
Demographic Data ◽  
Rehabilitation Program ◽  
Pharmacological Therapy ◽  
Chronic Obstructive ◽  
Borg Scale ◽  
Lung Function Decline ◽  
Obstructive Pulmonary Disease ◽  
Copd Patients ◽  
The Impact

Introduction. Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortality throughout the world. At present, the pharmacological therapy is not enough for a patient with COPD in regard to heath status and exercise tolerance. It requires additional therapies aimed to improve the quality of life, delay the lung function decline, increase exercise capacity, and reduce the respiratory symptoms and the number of exacerbations. Pulmonary rehabilitation program (PRP) has been shown to improve respiratory muscle, to optimize functional, psychosocial, behavioral and nutritional status. The aim of the present study was to asses the impact of PRP on COPD patients, focusing on the clinical benefits of PRP, which may further provide to the patients a good support for change. Material and method. Sixty-seven patients with clinically stable COPD were enrolled in this prospective study, consisting in a 6-weeks of PRP. There were recorded demographic data, smoking and medical history, and abnormal findings at the physical examination. All patients completed CAT (COPD Assessment Test) questionnaire and dyspnea on Borg scale, they performed spirometry, and six minutes walking test (6MWT), before and after the completion of the rehabilitation program. Results and Discussions. After the 6-week period of PRP, a large proportion of patients presented higher values of spirometric parameters, although the change was no statistically significant. The impact of COPD on the patient’s health was significantly improved, 58.2% of patients registered < 10 points of CAT questionnaire after PRP (p<0.05). 75% of patients reported a 0-5 points of dyspnea on Borg scale comparing with 29% before the PRP (p=0.0147), and 56% a 0-5 points of fatigue while only 25% of patients had the same score before the rehabilitation programme (p=0,022). Only 8 patients (11.94% vs 31.34%, p<0.05) reported a SaO2 lower than 90% after the PRP. The 6MWD was longer than 250m at the end of the 6-weeks of PRP for 38 patients (56.7% vs 22.38%, p<0.05). Conclusions. The present study showed that a PRP added to pharmacological treatment had a beneficial role of increasing the patient’ health status and exercise tolerance for COPD patients.

Contribution of hypoventilation to sleep oxygen desaturation in chronic obstructive pulmonary disease

1983 ◽  
Vol 55 (3) ◽  
pp. 669-677 ◽  
Author(s):  
D. W. Hudgel ◽  
R. J. Martin ◽  
M. Capehart ◽  
B. Johnson ◽  
P. Hill
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Rem Sleep ◽  
Minute Ventilation ◽  
Emg Activity ◽  
Chronic Obstructive ◽  
Electromyographic Activity ◽  
Obstructive Pulmonary Disease ◽  
Copd Patients ◽  
Residual Capacity

The purpose of this study was to determine whether hypoventilation contributes to the sleep hypoxemia observed in chronic obstructive pulmonary disease (COPD) patients and to examine breathing pattern and respiratory muscle electromyographic (EMG) activity during these episodes. Seven COPD patients who experienced at least a 10% decrease in arterial O2 saturation (SaO2) during rapid-eye-movement sleep (REM) sleep, six COPD patients with a minimal fall in SaO2, and five healthy subjects were studied. An inductance vest was used to quantitate ventilation. Skin electrodes were used to estimate diaphragmatic and intercostal electromyographic activity. Minute ventilation and EMG activity decreased in all three groups during sleep. Ventilation was irregular during REM sleep in the patients. During REM sleep, desaturating patients had longer episodes of hypopneic breathing [30 +/- 8 s (SE)] than nondesaturating patients (13 +/- 1 s, P less than 0.01). Desaturating patients spent a greater proportion of REM time hypopneic (53 +/- 5 vs. 28 +/- 5%, P less than 0.01) and had a greater decrease in functional residual capacity during hypopnea (P less than 0.05). SaO2 followed the hypopneic and hyperpneic breathing in REM sleep so that desaturating patients had more time for desaturation to occur. Thus hypoventilation appears to be a primary factor in sleep O2 desaturation in these patients. Because of the fall in lung volume, maldistribution of ventilation may also contribute.

scholarly journals Why are COPD patients unable to complete the outpatient pulmonary rehabilitation program?

2018 ◽  
Vol 15 (4) ◽  
pp. 411-418 ◽  
Author(s):  
Hulya Sahin ◽  
Ilknur Naz
Keyword(s):  
Pulmonary Rehabilitation ◽  
Rehabilitation Program ◽  
Forced Expiratory Volume ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Work Related ◽  
Program Compliance ◽  
Copd Patients ◽  
Lower Education Level ◽  
Group 2

This study aims to compare demographic and clinical characteristics of chronic obstructive pulmonary disease (COPD) patients who complete and fail to complete outpatient pulmonary rehabilitation (PR) program and to determine the reasons for not completing the program. Patients with COPD referred to the PR program were divided into two groups: Those who completed the program were classified as group 1 and those who did not complete were classified as group 2, and their data were compared. Patients who failed to complete the program were contacted through phone and asked why they ceased their participation in the program. In group 2, number of smoker patients and patients using nebulizer and receiving long-term oxygen treatment, emergency admissions, and dyspnea perception were higher ( p = 0.003, p < 0.001, p = 0.033, p = 0.011, p < 0.001, respectively); forced expiratory volume in one second (%) value, exercise capacity, and quality of life were lower ( p = 0.024, p = 0.001, p = 0.014, respectively). When considered from the sociodemographic perspective, group 2 had a lower education level and a higher rate of living alone ( p < 0.001). Factors impairing the program compliance were lack of motivation (49.0%), transportation problems (23.8%), COPD exacerbation (18.4%), work-related reasons (4.8%), and hospitalization (4.1%), respectively. Smokers and severe COPD patients fail to complete PR program due to various reasons, especially lack of motivation. It is very important for health practitioners to inform patients accurately and adopt a positive attitude.

Sign in / Sign up

Export Citation Format

Share Document