scholarly journals Case Report Associated with Aspergillosis and Hepatitis E Virus Coinfection in Himalayan Griffons

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Heng Li ◽  
Rining Zhu ◽  
Ruiping She ◽  
Chenglin Zhang ◽  
Ruihan Shi ◽  
...  
Keyword(s):  
Case Report ◽  
Hepatitis E Virus ◽  
Genomic Sequence ◽  
Hepatitis E ◽  
Lymphocyte Infiltration ◽  
Pathological Changes ◽  
Pathogen Identification ◽  
Internal Organs ◽  
First Report ◽  
Positive Results

This study involved a death which occurred in four Himalayan griffons housed in Beijing zoo, China. Based on pathogen identification and the pathological changes observed, we did characterize the fungi and Hepatitis E virus (HEV) in four dead Himalayan griffons. Pathological changes were severe. Membranous-like material was observed on the surface of the internal organs. Spleen was necrotic. Focal lymphocyte infiltration in the liver and many sunflower-like fungi nodules were evident in the tissues, especially in the kidney. PCR was used to identify the pathogen. Based on the 18SrRNA genomic sequence of known fungi, the results confirmed that all four dead Himalayan griffons were infected withAspergillus. At the same time the detection of HEV also showed positive results. To the best of our knowledge, this work appears to be the first report of concurrent presence of Aspergillosis and Hepatitis E virus in rare avian species.

scholarly journals Seroprevalence of Hepatitis E Virus Infection among Blood Donors in Bulgaria

Viruses ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 492
Author(s):  
Magdalena Baymakova ◽  
Krasimira Terzieva ◽  
Rumen Popov ◽  
Elisaveta Grancharova ◽  
Todor Kundurzhiev ◽  
...  
Keyword(s):  
Virus Infection ◽  
Hepatitis E Virus ◽  
Blood Donors ◽  
Hepatitis E ◽  
Elisa Test ◽  
Blood Samples ◽  
Wild Boars ◽  
Domestic Pigs ◽  
Specific Questionnaire ◽  
Positive Results

Hepatitis E virus (HEV) infection is widespread among domestic pigs, industrial swine, and wild boars in Bulgaria. The aim of the current research was to present the HEV seroprevalence among blood donors in Bulgaria. In the present study, 555 blood donors (479 males and 76 females) were enrolled from five districts in the country (Shumen, Pleven, Stara Zagora, Plovdiv, and Sofia districts). All blood samples were tested for anti-HEV IgG using the recomWell HEV IgG ELISA test (Mikrogen GmbH, Neuried, Germany). Each participating donor completed a short, structured, and specific questionnaire to document data on the current study. Anti-HEV IgG positive results were detected in 144 (25.9%) blood donors, including 129 (26.9%) males and 15 (19.7%) females. The established HEV seropositivity was 28.8% (23/80) in Shumen district, 23.2% (22/95) in Pleven district, 27.1% (38/140) in Stara Zagora district, 27.5% (44/160) in Plovdiv district, and 21.3% (17/80) in Sofia district. A high HEV seroprevalence was found for persons who declared that they were general hunters (48.7%; 19/39; p = 0.001) and hunters of wild boars (51.6%; 16/31; p = 0.001). We present the first seroprevalence rates of HEV infection in blood donors from Bulgaria. The results of our research showed high HEV seropositivity among blood donors.

scholarly journals Genotype 1 hepatitis E virus infection with acute acalculous cholecystitis as an extrahepatic symptom: a case report

2016 ◽  
Vol 44 (1) ◽  
Author(s):  
Ken Fujioka ◽  
Toshiki Nishimura ◽  
Masayuki Seki ◽  
Masanori Kinoshita ◽  
Nobuyuki Mishima ◽  
...  
Keyword(s):  
Case Report ◽  
Virus Infection ◽  
Hepatitis E Virus ◽  
Acalculous Cholecystitis ◽  
Hepatitis E ◽  
Acute Acalculous Cholecystitis ◽  
Genotype 1

scholarly journals First Report of the Presence of Hepatitis E Virus in Scottish-Harvested Shellfish Purchased at Retail Level

2018 ◽  
Vol 10 (2) ◽  
pp. 217-221 ◽  
Author(s):  
Zoe O’Hara ◽  
Claire Crossan ◽  
John Craft ◽  
Linda Scobie
Keyword(s):  
Hepatitis E Virus ◽  
Hepatitis E ◽  
First Report

Rat Hepatitis E Virus Linked to Severe Acute Hepatitis in an Immunocompetent Patient

2019 ◽  
Vol 220 (6) ◽  
pp. 951-955 ◽  
Author(s):  
Anton Andonov ◽  
Mark Robbins ◽  
Jamie Borlang ◽  
Jingxin Cao ◽  
Todd Hatchette ◽  
...  
Keyword(s):  
Acute Hepatitis ◽  
Hepatitis E Virus ◽  
Genomic Sequence ◽  
Hepatitis E ◽  
The United States ◽  
Immunocompetent Patient ◽  
Health Concern ◽  
Animal Reservoir ◽  
Hepatitis Infection ◽  
Severe Acute Hepatitis

Abstract Hepatitis E virus (HEV) is a major public health concern in developing countries where the primary transmission is via contaminated water. Zoonotic HEV cases have been increasingly described in Europe, Japan, and the United States, with pigs representing the main animal reservoir of infection. We report an unusual acute hepatitis infection in a previously healthy man caused by a rat HEV with a considerably divergent genomic sequence compared with other rat HEV strains. It is possible that rat HEV is an underrecognized cause of hepatitis infection, and further studies are necessary to elucidate its potential risk and mode of transmission.

Transmission of Hepatitis E Virus by Plasma Exchange: A Case Report

2016 ◽  
Vol 164 (12) ◽  
pp. 851 ◽  
Author(s):  
Vincent Mallet ◽  
Rebecca Sberro-Soussan ◽  
Anais Vallet-Pichard ◽  
Anne-Marie Roque-Afonso ◽  
Stanislas Pol
Keyword(s):  
Case Report ◽  
Plasma Exchange ◽  
Hepatitis E Virus ◽  
Hepatitis E

scholarly journals Case Report: Myocarditis along with fulminant hepatic failure secondary to acute hepatitis E infection

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 155
Author(s):  
Lajpat Rai ◽  
Osama Salam ◽  
Uzair Yaqoob ◽  
Ujala Zubair
Keyword(s):  
Case Report ◽  
Hepatitis E Virus ◽  
Hepatitis E ◽  
Myocardial Tissue ◽  
Muscle Rigidity ◽  
Loss Of Consciousness ◽  
Disease Course ◽  
Acute Hepatitis E ◽  
Asymptomatic Disease ◽  
Viral Serology

Myocarditis, defined as the inflammation of myocardial tissue has many causes which may be viral, metabolic or bacterial in origin. In this case, we report a patient aged 22 years who was admitted with presenting complains of loss of consciousness, generalized muscle rigidity and yellowish discoloration of the skin. During the course of his hospital stay, the patient developed signs of myocarditis and later died of hypotensive shock. Viral serology was positive for the presence of hepatitis E virus (HEV), a rare cause of myocarditis. HEV infection can range from asymptomatic disease course to fulminant hepatitis but in rare cases, it has been found to be a cause of myocarditis. This is so far the sixth case of hepatitis E induced myocarditis.

scholarly journals Case Report: Myocarditis along with fulminant hepatic failure secondary to acute hepatitis E infection

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 155
Author(s):  
Lajpat Rai ◽  
Osama Salam ◽  
Uzair Yaqoob ◽  
Ujala Zubair
Keyword(s):  
Case Report ◽  
Hepatitis E Virus ◽  
Hepatitis E ◽  
Myocardial Tissue ◽  
Muscle Rigidity ◽  
Loss Of Consciousness ◽  
Disease Course ◽  
Acute Hepatitis E ◽  
Asymptomatic Disease ◽  
Viral Serology

Myocarditis, defined as the inflammation of myocardial tissue has many causes which may be viral, metabolic or bacterial in origin. In this case we report a patient aged 22 years who was admitted with presenting complains of loss of consciousness, generalized muscle rigidity and yellowish discoloration of skin. During the course of his hospital stay, patient developed signs of myocarditis and later died of hypotensive shock. Viral serology was positive for the presence of hepatitis E virus (HEV), a rare cause of myocarditis. HEV infection can range from asymptomatic disease course to fulminant hepatitis but in rare cases it has been found to be a cause of myocarditis. This is so far the sixth case of hepatitis E induced myocarditis.

scholarly journals Analysis of the complete genomic sequence of an apparently avirulent strain of avian hepatitis E virus (avian HEV) identified major genetic differences compared with the prototype pathogenic strain of avian HEV

2007 ◽  
Vol 88 (5) ◽  
pp. 1538-1544 ◽  
Author(s):  
P. Billam ◽  
Z. F. Sun ◽  
X.-J. Meng
Keyword(s):  
Nucleotide Sequence Identity ◽  
Hepatitis E Virus ◽  
Genomic Sequence ◽  
Hepatitis E ◽  
Prototype Strain ◽  
Avirulent Strain ◽  
Sequence Identity ◽  
Avian Hepatitis E Virus ◽  
Avian Hev ◽  
Complete Genomic

Avian hepatitis E virus (HEV) was identified from chickens with hepatitis–splenomegaly syndrome. In this study, the complete genomic sequence of an apparently avirulent strain of avian HEV was determined to be 6649 nt in length, excluding the poly(A) tail, which is 5 nt shorter than the prototype avian HEV. Sequence analyses revealed that the ORF1 has 89.6 % nucleotide sequence identity, with numerous non-silent mutations and deletions, compared to the prototype strain. The ORF2 capsid gene showed 90.7 % sequence identity with six non-silent mutations, and ORF3 had four non-silent mutations with 97 % sequence identity. Overall, the apparently avirulent strain shares only 90.1 % nucleotide sequence identity with the prototype strain. The identification of significant non-silent mutations in the capsid gene and other regions suggests that these mutations may play a role in HEV attenuation. This is the first report of the full-length sequence of an apparently avirulent strain of HEV.

scholarly journals Hepatitis E Virus Infection in Pigs: A First Report from Zambia

2021 ◽  
pp. 1-12
Author(s):  
Herman M. Chambaro ◽  
Michihito Sasaki ◽  
Walter Muleya ◽  
Masahiro Kajihara ◽  
Misheck Shawa ◽  
...  
Keyword(s):  
Virus Infection ◽  
Hepatitis E Virus ◽  
Hepatitis E ◽  
First Report
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