scholarly journals Retracted: Nontraumatic Lesions of the Clavicle in a Paediatric Population: Incidence and Management

2015 ◽  
Vol 2015 ◽  
pp. 1-1
Keyword(s):  
Paediatric Population ◽  
Population Incidence

Pituitary incidentalomas in paediatric population: Incidence and characteristics

2020 ◽  
Author(s):  
Muhammed Shareef ◽  
Mona P. Nasrallah ◽  
Natally AlArab ◽  
Lamya A. Atweh ◽  
Catherina Zadeh ◽  
...  
Keyword(s):  
Paediatric Population ◽  
Population Incidence

scholarly journals Thirty-Five Years of Thyroid Cancer Experience in a Paediatric Population: Incidence Trends in Lithuania between 1980 and 2014

2016 ◽  
Vol 6 (1) ◽  
pp. 40-46 ◽  
Author(s):  
Rima Bėrontienė ◽  
Edita Jašinskienė ◽  
Rosita Kiudelienė ◽  
Gintaras Kuprionis ◽  
Jurgita Makštienė ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Paediatric Population ◽  
Incidence Trends ◽  
Population Incidence ◽  
Cancer Experience

Pituitary incidentalomas in paediatric population: Incidence and characteristics

2021 ◽  
Author(s):  
Shareef M ◽  
Nasrallah MP ◽  
AlArab N ◽  
Atweh LA ◽  
Zadeh C ◽  
...  
Keyword(s):  
Paediatric Population ◽  
Population Incidence

Hypercalcaemia and osteonecrosis of the jaw in association with denosumab use in the paediatric population

2019 ◽  
Author(s):  
Christie-Lee Wall ◽  
Verity Pacey ◽  
Kelly Gray ◽  
Richard McGee ◽  
Melissa Fiscaletti ◽  
...  
Keyword(s):  
Paediatric Population ◽  
Osteonecrosis Of The Jaw

Prerequisites to support high-quality clinical trials in children and young people

2020 ◽  
pp. archdischild-2019-318677
Author(s):  
Steven Hirschfeld ◽  
Florian B Lagler ◽  
Jenny M Kindblom
Keyword(s):  
Clinical Trials ◽  
Healthcare Delivery ◽  
Paediatric Population ◽  
Ecosystem Functions ◽  
Healthcare Delivery System ◽  
High Quality ◽  
Children And Young People ◽  
The Right ◽  
Support Decision Making

Children have the right to treatment based on the same quality of information that guides treatment in adults. Without the proper evaluation of medicinal products and devices in paediatric clinical trials that are designed to meet the rigorous standards of the competent authorities, children are discriminated from advances in medicine. There are regulatory, scientific and ethical incentives to address the knowledge gap regarding efficacy and safety of medicines in the paediatric population. High-quality clinical trials involving children of all ages can generate data that will ultimately close the knowledge gaps and support decision making.For clinical trials that enrol children, the needs are specialised and often resource intensive. Prerequisites for successful paediatric clinical trials are personnel with training in both paediatrics and neonatology and expertise in clinical trials in these populations. Moreover, national and international networks for efficient collaboration, dissemination of information, and sharing of resources and expertise are also needed, together with competent, efficient and high-quality local infrastructure with effective processes. Monitoring and oversight bodies with the relevant competence, including expertise in paediatrics, is also an important prerequisite for paediatric clinical trials. Compromise in any of these components will compromise the downstream results.This paper discusses the structures and competences needed in order to perform effective, high-quality paediatric clinical trials with the ultimate goal of better medicines and treatments for children. We propose a model of examining the process as a series of components that each has to be optimised, then all the components are actively optimised to function together as an ecosystem, and the resulting ecosystem functions well with the general research system and the healthcare delivery system.

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