scholarly journals Automatic Classification of Normal and Cancer Lung CT Images Using Multiscale AM-FM Features

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Eman Magdy ◽  
Nourhan Zayed ◽  
Mahmoud Fakhr

Computer-aided diagnostic (CAD) systems provide fast and reliable diagnosis for medical images. In this paper, CAD system is proposed to analyze and automatically segment the lungs and classify each lung into normal or cancer. Using 70 different patients’ lung CT dataset, Wiener filtering on the original CT images is applied firstly as a preprocessing step. Secondly, we combine histogram analysis with thresholding and morphological operations to segment the lung regions and extract each lung separately. Amplitude-Modulation Frequency-Modulation (AM-FM) method thirdly, has been used to extract features for ROIs. Then, the significant AM-FM features have been selected using Partial Least Squares Regression (PLSR) for classification step. Finally,K-nearest neighbour (KNN), support vector machine (SVM), naïve Bayes, and linear classifiers have been used with the selected AM-FM features. The performance of each classifier in terms of accuracy, sensitivity, and specificity is evaluated. The results indicate that our proposed CAD system succeeded to differentiate between normal and cancer lungs and achieved 95% accuracy in case of the linear classifier.

Author(s):  
V. Vijaya Kishore ◽  
R.V.S. Satyanarayana

A vital necessity for clinical determination and treatment is an opportunity to prepare a procedure that is universally adaptable. Computer aided diagnosis (CAD) of various medical conditions has seen a tremendous growth in recent years. The frameworks combined with expanding capacity, the coliseum of CAD is touching new spaces. The goal of proposed work is to build an easy to understand multifunctional GUI Device for CAD that performs intelligent preparing of lung CT images. Functions implemented are to achieve region of interest (ROI) segmentation for nodule detection. The nodule extraction from ROI is implemented by morphological operations, reducing the complexity and making the system suitable for real-time applications. In addition, an interactive 3D viewer and performance measure tool that quantifies and measures the nodules is integrated. The results are validated through clinical expert. This serves as a foundation to determine, the decision of treatment and the prospect of recovery.


Sensors ◽  
2021 ◽  
Vol 21 (1) ◽  
pp. 268
Author(s):  
Yeganeh Jalali ◽  
Mansoor Fateh ◽  
Mohsen Rezvani ◽  
Vahid Abolghasemi ◽  
Mohammad Hossein Anisi

Lung CT image segmentation is a key process in many applications such as lung cancer detection. It is considered a challenging problem due to existing similar image densities in the pulmonary structures, different types of scanners, and scanning protocols. Most of the current semi-automatic segmentation methods rely on human factors therefore it might suffer from lack of accuracy. Another shortcoming of these methods is their high false-positive rate. In recent years, several approaches, based on a deep learning framework, have been effectively applied in medical image segmentation. Among existing deep neural networks, the U-Net has provided great success in this field. In this paper, we propose a deep neural network architecture to perform an automatic lung CT image segmentation process. In the proposed method, several extensive preprocessing techniques are applied to raw CT images. Then, ground truths corresponding to these images are extracted via some morphological operations and manual reforms. Finally, all the prepared images with the corresponding ground truth are fed into a modified U-Net in which the encoder is replaced with a pre-trained ResNet-34 network (referred to as Res BCDU-Net). In the architecture, we employ BConvLSTM (Bidirectional Convolutional Long Short-term Memory)as an advanced integrator module instead of simple traditional concatenators. This is to merge the extracted feature maps of the corresponding contracting path into the previous expansion of the up-convolutional layer. Finally, a densely connected convolutional layer is utilized for the contracting path. The results of our extensive experiments on lung CT images (LIDC-IDRI database) confirm the effectiveness of the proposed method where a dice coefficient index of 97.31% is achieved.


Lung cancer is a serious illness which leads to increased mortality rate globally. The identification of lung cancer at the beginning stage is the probable method of improving the survival rate of the patients. Generally, Computed Tomography (CT) scan is applied for finding the location of the tumor and determines the stage of cancer. Existing works has presented an effective diagnosis classification model for CT lung images. This paper designs an effective diagnosis and classification model for CT lung images. The presented model involves different stages namely pre-processing, segmentation, feature extraction and classification. The initial stage includes an adaptive histogram based equalization (AHE) model for image enhancement and bilateral filtering (BF) model for noise removal. The pre-processed images are fed into the second stage of watershed segmentation model for effectively segment the images. Then, a deep learning based Xception model is applied for prominent feature extraction and the classification takes place by the use of logistic regression (LR) classifier. A comprehensive simulation is carried out to ensure the effective classification of the lung CT images using a benchmark dataset. The outcome implied the outstanding performance of the presented model on the applied test images.


2021 ◽  
Vol 9 ◽  
Author(s):  
Jinglun Liang ◽  
Guoliang Ye ◽  
Jianwen Guo ◽  
Qifan Huang ◽  
Shaohui Zhang

Malignant pulmonary nodules are one of the main manifestations of lung cancer in early CT image screening. Since lung cancer may have no early obvious symptoms, it is important to develop a computer-aided detection (CAD) system to assist doctors to detect the malignant pulmonary nodules in the early stage of lung cancer CT diagnosis. Due to the recent successful applications of deep learning in image processing, more and more researchers have been trying to apply it to the diagnosis of pulmonary nodules. However, due to the ratio of nodules and non-nodules samples used in the training and testing datasets usually being different from the practical ratio of lung cancer, the CAD classification systems may easily produce higher false-positives while using this imbalanced dataset. This work introduces a filtering step to remove the irrelevant images from the dataset, and the results show that the false-positives can be reduced and the accuracy can be above 98%. There are two steps in nodule detection. Firstly, the images with pulmonary nodules are screened from the whole lung CT images of the patients. Secondly, the exact locations of pulmonary nodules will be detected using Faster R-CNN. Final results show that this method can effectively detect the pulmonary nodules in the CT images and hence potentially assist doctors in the early diagnosis of lung cancer.


Author(s):  
Satya Praksh Sahu ◽  
Bhawna Kamble

Lung segmentation is the initial step for detection and diagnosis for lung-related abnormalities and disease. In CAD system for lung cancer, this step traces the boundary for the pulmonary region from thorax in CT images. It decreases the overhead for a further step in CAD system by reducing the space for finding the ROIs. The major issue and challenging task for the segmentation is the inclusion of juxtapleural nodules in the segmented lungs. The chapter attempts 3D lung segmentation of CT images using active contour and morphological operations. The major steps in the proposed approach contain: preprocessing through various techniques, Otsu's thresholding for the binarizing the image; morphological operations are applied for elimination of undesired region and, finally, active contour for the segmentation of the lungs in 3D. For experiment, 10 subjects are taken from the public dataset of LIDC-IDRI. The proposed method achieved accuracies 0.979 Jaccard's similarity index value, 0.989 Dice similarity coefficient, and 0.073 volume overlap error when compared to ground truth.


2021 ◽  
Author(s):  
Omid Talakoub

One of the most important areas of biomedical engineering is medical imaging. Fully automated schemes are currently being explored as Computer-Aided Diagnosis (CAD) systems to provide a second opinion to medical professionals; of these systems, abnormal region detector in medical images is one of the most critical CAD systems in development. The primary motivation in using these systems is due to the fact that reading an enormous number of images is a time-consuming task for the radiologist. This task can be sped up by using a CAD system which highlights abnormal regions of interest. Low false positive rates and high sensitivity are essential requirement[s] of such a system. The initial requirement of processing any organ is an accurate segmentation of the target of interest in the images. A segmentation method based on the wavelet transformation is proposed which accurately extracts lung regions in the thoracic CT images. After this step, an Aritifical Intelligence system, known as Least Squares Support Vector Machine (LS-SVM), is employed to classify nodules within the regions of interest. It is a well known fact that the lung nodules, except the pleural nodules, are mostly spherical structures whereas other structures including blood vessels are shaped as other structures such as tubular. Therfore, an enhancment filter is developed in which spherical structures are accentuated. Processing three different real databases revealed that the proposed system has reached the objective of a CAD system to provide reliable opinion for the doctors in the diagnosis fashion.


Early recognition and classification of pulmonary nodules by the use of computer-aided diagnosis (CAD) tools finds useful to reduce the death rate due to the illness of lung cancer. This paper devises a new CAD tool utilizing a segmentation based classification process for lung CT images. Initially, the input CT images are pre-processed by image enhancement and noise removal process. Then, watershed segmentation model is employed for the segmentation of the pre-processed images. Subsequently, the feature extraction process is carried out using Xecption model and random forest (RF) classifier is used of the identification of lung CT images as normal, benign or malignant. The use of RF model results to effective classification of the applied images. This model undergoes extensive experimentation against a benchmark lung CT image dataset and the results are investigated under several aspects. The obtained outcome pointed out the significant performance of the presented model over the compared methods.


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