scholarly journals Benign Lymphoid Hyperplasia Presenting as Bilateral Scleral Nodules

2015 ◽  
Vol 2015 ◽  
pp. 1-3
Author(s):  
Ricardo J. Cumba ◽  
Rene Vazquez-Botet

Purpose. To report a case of transient lymphoid hyperplasia presenting as bilateral nodular scleral mass in a young male patient.Design. Observational case report.Methods. Chart review. Causes of scleritis were considered and excluded based on detailed history, physical examination, and laboratory investigations.Results. Excisional biopsy of scleral lesions indicated lymphoid tissue. Immunohistochemical studies revealed a polyclonal population of T and B cells consistent with a benign reactive process.Conclusions. Chronic exposure of the ocular adnexa to many allergens and irritants may lead to activation of the inflammatory cascade. In severely allergic patients activation may be exponential and elicit an immune-mediated response resulting in a transient lymphoid reactive process.

2018 ◽  
Vol 40 (4) ◽  
pp. 332-335
Author(s):  
P V Kuzyk ◽  
M A Savchyna ◽  
S G Gychka

Aim: To describe the case of rare benign lymphoproliferative disorder — pulmonary nodular lymphoid hyperplasia in the patient with previous pulmonary tuberculosis. Materials and Methods: In the case of pulmonary nodular lymphoid hyperplasia clinical, laboratory, instrumental and morphological examination was performed. Results: 44-year-old woman in 7 years after successfully treated infiltrative drug-susceptible tuberculosis of the right lung, was hospitalized with a suspected tumor of the left lung root. The patient underwent left-sided pneumonectomy with lymph nodes dissection. The results of histopathological and immunohistochemical studies evidenced on nodular lymphoid hyperplasia of the left lung. Conclusion: Pulmonary nodular lymphoid hyperplasia is a rare lymphoproliferative disorder of the lung with favorable prognosis. For the purpose of differential diagnosis, it is necessary to apply immunohistochemistry.


2017 ◽  
Vol 5 (2) ◽  
pp. 20-23
Author(s):  
Toshihide Watanabe ◽  
Chonji Fukumoto ◽  
Kazuya Hiroshima ◽  
Kohei Kawasaki

1987 ◽  
Vol 16 (1) ◽  
pp. 18-26 ◽  
Author(s):  
G. Bradley ◽  
J. H. P. Main ◽  
B. D. Birt ◽  
L. From

2005 ◽  
Vol 6 (3) ◽  
pp. 111-119 ◽  
Author(s):  
Sunitha Carnelio ◽  
Gabriel Rodrigues

Abstract Lymphoid hyperplasia of the tongue is a very rare benign lymphoproliferative lesion that closely resembles carcinoma or lymphoma, clinically or histopathologically. A case of benign lymphoid hyperplasia (BLH) of the tongue is reported. Clinically this lesion presented as a painless ulcer, which mimicked carcinoma of the tongue. Microscopy showed typical histologic features of multiple germinal centers with a rim of small mature lymphocytes together with a mixed, mainly mononuclear infiltrate which clinched the diagnosis of benign lymphoid hyperplasia. This diagnosis averted extensive investigations and major surgery. The etiology of these lesions is unknown. Their distinction from carcinoma and lymphoma is discussed. Citation Carnelio S, Rodrigues G. Benign Lymphoid Hyperplasia of the Tongue Masquerading as Carcinoma: Case Report and Literature Review. J Contemp Dent Pract 2005 August;(6)3:111-119.


2009 ◽  
Vol 13 (3) ◽  
pp. 172-175 ◽  
Author(s):  
Nawaf Al-Mutairi ◽  
Azari Al-Doukhi

Background: Psoriasis is an immune-mediated, chronic, inflammatory disease that significantly impairs both physical and emotional aspects of an individual's quality of life. Vitiligo leads to depigmentation of skin, in which some or all melanocytes in the interfollicular epidermis and occasionally those in the hair follicles are selectively destroyed. The coexistence of the two disorders is rarely seen. Objective: To report two cases of the rare coexistence of psoriasis and vitiligo in a family. Methods: After providing informed written consent, both patients were given alefacept 15 mg/kg weekly injections for 12 weeks. The patients were monitored both clinically and with all relevant laboratory investigations. These patients were then followed up once a month for 2 years. Results: Treatment with alefacept led to complete clearance of vitiligo along with the expected improvement in psoriasis. In the 2-year follow-up, vitiligo did not recur, although psoriasis relapsed and was appropriately treated. Conclusion: Use of alefacept in vitiligo may turn out to be a possible novel off-label treatment option in vitiligo. But the results need to be reproduced in larger studies


2011 ◽  
Vol 42 (11) ◽  
pp. 1813-1818 ◽  
Author(s):  
Michele K. McElroy ◽  
Anna A. Kulidjian ◽  
Rana Sumit ◽  
Noel Weidner

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