scholarly journals Morphometry of the Orbit in East-European Population Based on Three-Dimensional CT Reconstruction

2015 ◽  
Vol 2015 ◽  
pp. 1-10
Author(s):  
Stanisław Nitek ◽  
Leopold Bakoń ◽  
Mansoor Sharifi ◽  
Maciej Rysz ◽  
Lechosław P. Chmielik ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Population Based ◽  
European Population ◽  
Optic Canal ◽  
Ct Reconstruction ◽  
Superior Orbital Fissure ◽  
East European ◽  
Inferior Margin ◽  
Orbital Opening ◽  
Supraorbital Foramen

Objectives. To determine safe distances within the orbit outlining reliable operative area on the basis of multislice computed tomography (MSCT) scans. Patients and Methods. MSCT of orbits of 50 Caucasian patients (26 males and 24 females, mean age 56) were analysed. Native scans resolutions were in all cases 0.625 mm. Measurements were done in postprocessing workstation with 2D and 3D reconstructions. The safe distances values were calculated by subtracting three standard deviations from the arithmetical average (X=AVG-3  STD). This method was chosen because this range covers 99.86% of every population. Results. The results of the measurements in men and women, respectively, are as follows (1) distance from optic canal to supraorbital foramen, mean 46,49 mm and 43,29 mm, (2) distance from the optic canal to maxillozygomatic suture at the inferior margin of the orbit mean 45,24 mm and 42,8 mm, (3) distance from the optic canal to frontozygomatic suture 46,15 mm and 43,58 mm, (4) distance from the optic canal to anterior lacrimal crest 40,40 mm and 38,39 mm, (5) distance from superior orbital fissure to the frontozygomatic suture 34,06 mm and 32,62 mm, and (6) distance from supraorbital foramen to the superior orbital fissure 42,32 mm and 39,39 mm. Conclusion. The most probable safe distances calculated by adopted formula were for the superior orbital fissure 23,39–30,58 mm and for the orbital opening of the optic canal 31,9–38,0 mm from the bony structures of the orbital entrance depending on the orbital quadrant.

scholarly journals Prenatal and postnatal exposure to acetaminophen in relation to autism spectrum and attention-deficit and hyperactivity symptoms in childhood: Meta-analysis in six European population-based cohorts

2021 ◽  
Author(s):  
Silvia Alemany ◽  
Claudia Avella-García ◽  
Zeyan Liew ◽  
Raquel García-Esteban ◽  
Kosuke Inoue ◽  
...  
Keyword(s):  
Attention Deficit ◽  
Clinical Symptoms ◽  
Meta Analysis ◽  
Collaborative Study ◽  
Population Based ◽  
Autism Spectrum ◽  
European Population ◽  
Autism Spectrum Conditions ◽  
Adhd Symptoms ◽  
Postnatal Exposure

AbstractThe potential etiological role of early acetaminophen exposure on Autism Spectrum Conditions (ASC) and Attention-Deficit/Hyperactivity Disorder (ADHD) is inconclusive. We aimed to study this association in a collaborative study of six European population-based birth/child cohorts. A total of 73,881 mother–child pairs were included in the study. Prenatal and postnatal (up to 18 months) acetaminophen exposure was assessed through maternal questionnaires or interviews. ASC and ADHD symptoms were assessed at 4–12 years of age using validated instruments. Children were classified as having borderline/clinical symptoms using recommended cutoffs for each instrument. Hospital diagnoses were also available in one cohort. Analyses were adjusted for child and maternal characteristics along with indications for acetaminophen use. Adjusted cohort-specific effect estimates were combined using random-effects meta-analysis. The proportion of children having borderline/clinical symptoms ranged between 0.9 and 12.9% for ASC and between 1.2 and 12.2% for ADHD. Results indicated that children prenatally exposed to acetaminophen were 19% and 21% more likely to subsequently have borderline or clinical ASC (OR = 1.19, 95% CI 1.07–1.33) and ADHD symptoms (OR = 1.21, 95% CI 1.07–1.36) compared to non-exposed children. Boys and girls showed higher odds for ASC and ADHD symptoms after prenatal exposure, though these associations were slightly stronger among boys. Postnatal exposure to acetaminophen was not associated with ASC or ADHD symptoms. These results replicate previous work and support providing clear information to pregnant women and their partners about potential long-term risks of acetaminophen use.

scholarly journals Three-dimensional study of the orbit-related structures according to sex, age and skeletal deformities

2021 ◽  
Vol 10 (11) ◽  
pp. e77101119381
Author(s):  
Tamara Fernandes de Castro ◽  
Liogi Iwaki Filho ◽  
Amanda Lury Yamashita ◽  
Fernanda Chiguti Yamashita ◽  
Naiara Caroline Aparecido dos Santos ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Class I ◽  
Class Iii ◽  
Gamma Model ◽  
Orbital Reconstruction ◽  
Skeletal Deformities ◽  
Infraorbital Canal ◽  
Male Patients ◽  
Post Hoc ◽  
Supraorbital Foramen

Objective: This study aimed to evaluate the relations between orbit-related structures and sex, age and skeletal deformities using cone-beam computed tomography (CBCT). Methods: This retrospective study evaluated 216 consecutive CBCT scans of patients, who were divided according to: sex (male, n=105; female, n=111), age (A1: 18-32 years, n=71; A2: 33-47 years, n=78; A3: 48-62 years, n=67), and skeletal deformities (Class I, n=70; Class II, n=75; Class III, n=71). The supraorbital foramen (SOF) location, volume of orbit, optic canal (OC) and infraorbital canal (IOC) were evaluated. Results were analyzed using the Gamma model test. The Tukey-Kramer post-hoc test was used to compare the variables with three factors (p<0.05). Results: The IOC volume showed higher values for male, A3 and class I patients. The SOF location and the orbital volume also showed higher values for male patients. Regarding the volume of CO, it showed higher values ​​for male and class I patients. Conclusions: According to our results, sex has been shown to have a significant influence on orbit-related structures. Age and skeletal deformities also influenced the volume of IOC and OC. These results eventually help the clinical practice, being useful for orbital reconstruction surgeries, anthropological studies, gender identification and identification of susceptibility to pathological conditions related to sexual dimorphism.

Three-dimensional spiral CT reconstruction in a patient with massive cerebral air embolism

2004 ◽  
Vol 11 (2) ◽  
pp. 87-88 ◽  
Author(s):  
Fatih Alper ◽  
Mecit Kantarci ◽  
Omer Onbas ◽  
Adnan Okur ◽  
Naci Ceviz
Keyword(s):  
Three Dimensional ◽  
Air Embolism ◽  
Spiral Ct ◽  
Ct Reconstruction ◽  
Cerebral Air Embolism

Inverse modeling of transient three-dimensional core-scale two-phase flows

2021 ◽  
Author(s):  
Andrea Manzoni ◽  
Aronne Dell'Oca ◽  
Martina Siena ◽  
Alberto Guadagnini
Keyword(s):  
Capillary Pressure ◽  
Random Noise ◽  
Three Dimensional ◽  
Population Based ◽  
Model Parameters ◽  
Reference Scenario ◽  
Two Phase ◽  
De Algorithm ◽  
Continuum Scale ◽  
Available Information

&lt;p&gt;We consider transient three-dimensional (3D) two-phase (oil and water) flows, taking place at the core-scale. In this context, we aim at exploiting the full information content associated with available information of (i) the 3D distribution of oil saturation and (ii) the overall pressure difference across the rock sample, to estimate the set of model parameters. We consider a continuum-scale description of the system behavior upon relying on the widely employed Brooks-Corey model for the characterization of relative permeabilities and on the capillary pressure correlation introduced by Skjaeveland et al. (2000). To provide a transparent way of assessing the results of the inversion, we rely on a synthetic reference scenario. The latter is intended to mimic having at our disposal 3D and section-averaged distributions of (time-dependent) oil saturations of the kind that can be acquired during typical laboratory experiments. These are in turn corrupted by way of a random noise, to address the influence of experimental uncertainties. We focus on diverse scenarios encompassing imbibition and drainage conditions. We employ two population-based optimization algorithms, i.e., (i) the particle swarm optimization (PSO); and (ii) the differential evolution (DE), which enable one to effectively tackle the high-dimensionality parameters space (i.e., 12 dimensions in our setting) we consider. Model calibration results are of satisfactory quality for the majority of the tested scenarios, whereas the DE algorithm is associated with highest effectiveness.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;References&lt;/strong&gt;&lt;/p&gt;&lt;p&gt;S.M. Skjaeveland; L.M. Siqveland; A. Kjosavik; W.L. Hammervold Thomas; G.A. Virnovsky (2000). Capillary Pressure Correlation for Mixed-Wet Reservoirs SPE Res Eval &amp; Eng 3 (01): 60&amp;#8211;67. https://doi.org/10.2118/60900-PA&lt;/p&gt;

Abstract 2917: Outcome Prediction With A Population-based Ischemic Stroke Atlas

Stroke ◽  
2012 ◽  
Vol 43 (suppl_1) ◽  
Author(s):  
Wieslaw L Nowinski ◽  
Varsha Gupta ◽  
Guoyu Qian ◽  
Wojciech Ambrosius ◽  
Jie He ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Outcome Prediction ◽  
Three Dimensional ◽  
Prediction Method ◽  
Population Based ◽  
Novel Approach ◽  
History Of ◽  
High Prediction ◽  
Predicted Values ◽  
One Year

Outcome prediction is critical in stroke patient management. We propose a novel approach combining imaging with parameters (including history, hospitalization, demographics, clinical and outcome) for a population of patients in the Probabilistic Stroke Atlas (PSA) along with prediction engine. The PSA aggregates multiplicity of data for a population of stroke patients and presents them in image format. The PSA is composed from a series of three-dimensional (3D) image volumes including scans and parameters. A cohort of over 700 ischemic stroke generally treated patients with 176 parameters per patient, and CT scan performed at admission and on day 7 was acquired. Outcome measurements were assessed up to one year after stroke onset. Cases with old infarcts, infarcts in both hemispheres, and hemorrhagic transformations were rejected. This data was post-processed to build the PSA and then the PSA was used for prediction. The infarcts were delineated on CT scans and their 3D surface models constructed and normalized. The PSA was calculated from the normalized 3D infarct models as frequency of stroke occurrence. Similar maps were calculated for the following parameters: Age; Sex; Survival; NIH Stroke Scale (NIHSS); Barthel Index (BI) at 30, 90, 180, 360 days; modified Rankin Scale (mRS) at 7, 30, 90, 180, 360 days; White blood cell count; C-reative protein; Glucose at emergency department; History of hypertension; and History of diabetes. The PSA was used for prediction of mRS and BI for 50 stroke subjects. For a given case to be predicted, the infarct was delineated and analyzed by the PSA mapped on the scan. The predicted values of the parameters from the PSA were compared with the actual values of the parameters measured in up to 1-year neurological follow up. The accuracy was defined as 100*(1-(actual value-predicted value)/actual value)%. The mean prediction accuracy of mRS at (7, 30, 90, 180, 360) days is (89.7, 90.7, 92.1, 87.0, 83.3)% and that for BI at (30, 90, 180, 360) days is (90.0, 95.4, 94.4, 92.2)% respectively. This novel prediction method has high prediction rates. It can be applied to any other parameters. The PSA is dynamic and its power can increase with additional cases.

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