scholarly journals Tracheal Epstein-Barr Virus-Associated Smooth Muscle Tumour in an Hiv-Positive Patient

2014 ◽  
Vol 21 (6) ◽  
pp. 334-336 ◽  
Author(s):  
Giulio S Dominelli ◽  
Rachel Jen ◽  
Kirily Park ◽  
Tawimas Shaipanich

Epstein-Barr virus-related smooth muscle tumours (EBV-SMTs) are a rare but well recognized non-AIDS-defining malignancy that can also be found in several other immunosuppressed states. Pulmonary involvement of EBVSMTs is not uncommon, but it can present with multifocal lesions in any anatomical site. The present article describes an HIV-positive woman with dyspnea who was found to have a large tracheal EBV-SMT. The authors discuss their approach to diagnosis and management, and present unique follow-up bronchoscopic imaging.

2007 ◽  
Vol 122 (1) ◽  
pp. 100-104 ◽  
Author(s):  
E C Gan ◽  
D P C Lau ◽  
K L Chuah

AbstractA case is presented of a 36-year-old Chinese woman with a renal transplant for end-stage renal failure due to Goodpasture's syndrome. She presented with a year's history of throat discomfort and acid regurgitation into her throat. Videolaryngoscopy revealed bilateral vocal process granuloma, presumed to be due to gastroesophageal reflux. A four-week course of high dose omeprazole was prescribed. On follow up a month later, the granulomas had enlarged, and laser excision was undertaken. Histological and immunohistochemical staining was consistent with Epstein–Barr virus-associated smooth muscle tumour. This is believed to be the first reported case in the English literature of such a tumour affecting the vocal process. The aim of this paper is to present the pathogenesis, clinical behaviour and treatment of Epstein–Barr virus-associated smooth muscle tumour, and to review the literature concerning the differential diagnosis of polypoid vocal process lesions.


Pathology ◽  
2020 ◽  
Vol 52 ◽  
pp. S133
Author(s):  
Yalda Hakemi ◽  
Amir Hadji-Ashrafy ◽  
Vishnu Subramanian

Pathology ◽  
2020 ◽  
Vol 52 ◽  
pp. S65
Author(s):  
Sameer Ansar ◽  
Richard Boyle ◽  
Wendy Brown ◽  
Rooshdiya Karim ◽  
Peter Luk ◽  
...  

2006 ◽  
Vol 7 (11) ◽  
pp. 955-957 ◽  
Author(s):  
Han Chong Toh ◽  
Marissa Teo ◽  
Kong Wee Ong ◽  
Victor Lee ◽  
Errol Chan ◽  
...  

2018 ◽  
Vol 16 ◽  
pp. 89-91
Author(s):  
Dale Wood ◽  
Admire Matsika ◽  
Bhuvana Srinivasan ◽  
Roger Watson

2018 ◽  
Vol 20 (2) ◽  
pp. e12841 ◽  
Author(s):  
Hany M. El Hennawy ◽  
Wael Habhab ◽  
Abdulmonem Almutawa ◽  
Sumaih Shinawi ◽  
Abdulrahman Al Ayad ◽  
...  

2019 ◽  
Vol 30 (6) ◽  
pp. 605-609 ◽  
Author(s):  
C Wujanto ◽  
S Vasoo ◽  
CL Nandini ◽  
CP Nolan ◽  
VYP Ng ◽  
...  

Epstein–Barr virus-associated smooth muscle tumour (EBV-SMT) is a unique condition which affects immunocompromised patients. We describe the favourable outcome of a patient with acquired immune deficiency syndrome (AIDS)-related multi-centric EBV-SMT involving the posterior fossa and spine treated with surgery and adjuvant volumetric modulated arc therapy comprising 50 Gy in 25 fractions to four sites initially to the brain and lumbar spine followed by sixth to ninth thoracic vertebrae (T6–T9) and sacrum a year later. Reported literature suggests that AIDS-related EBV-SMTs are more sensitive to radiotherapy. However, compliance to the highly active anti-retroviral therapy is paramount in preventing future recurrence. This case also emphasises the importance of multidisciplinary management in ensuring the best possible outcome.


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