scholarly journals Nurses’ Roles and Experiences with Enhancing Adherence to Tuberculosis Treatment among Patients in Burundi: A Qualitative Study

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Marie Carlsson ◽  
Stina Johansson ◽  
Remy-Paul Bosela Eale ◽  
Berthollet Bwira Kaboru
Keyword(s):  
Treatment Adherence ◽  
Treatment Process ◽  
Treatment Success ◽  
Critical Role ◽  
Treatment Compliance ◽  
Qualitative Approach ◽  
Tb Control ◽  
Tb Treatment ◽  
Poor Treatment ◽  
Critical Resources

Background. In TB control, poor treatment adherence is a major cause of relapse and drug resistance. Nurses have a critical role in supporting patients in TB treatment process. Yet, very little research has been done to inform policymakers and practitioners on nurses’ experiences of treatment adherence among patients with TB.Aim. To describe nurses’ experiences of supporting treatment adherence among patients with tuberculosis in Burundi.Method. The study adopted qualitative approach with a descriptive design. A purposive sampling was performed. Eight nurses were selected from two TB treatment centers in Burundi. Content analysis was used to analyze the data.Result. According to the nurses, most patients complete their treatment. Educating patients, providing the medication, observing and following up treatment, and communicating with the patients were the key tasks by nurses to support adherence. Causes for interruption were medication-related difficulties, poverty, and patients’ indiscipline. Treatment adherence could also be affected by patients’ and nurses’ feelings. Providing transportation and meals could enhance treatment compliance.Conclusion. Nurses are critical resources to TB treatment success. In a poverty stricken setting, nurses’ work could be facilitated and adherence further could be enhanced if socioeconomic problems (transportation and nutritional support) were alleviated.

scholarly journals Perspective Of Stakeholders On The Sustainability Of Tuberkulosis Program

2020 ◽  
Vol 9 (1) ◽  
pp. 224-240
Author(s):  
Indasah Indasah ◽  
Dedi Saifulah ◽  
Anita Restu Korbaffo
Keyword(s):  
Prevention And Control ◽  
Case Study Research ◽  
Qualitative Approach ◽  
Service Program ◽  
Tb Control ◽  
Descriptive Research ◽  
Tb Treatment ◽  
Complete Treatment ◽  
And Control

This research is a type of descriptive research using a qualitative approach design using a case study research design. Funding for the TB program in Pasuruan Regency was sourced from the APBD and also Health Operational Assistance sourced from the Special Allocation Fund decreased. The budget for TB prevention prevention programs is absorbed entirely But the performance of achieving the discovery targets is still not significant. Still not found the whole case, complete treatment has not been maximized, some even DO. TB control activities allocated for TB prevention and control services appear to be relatively small compared to the TB treatment budget. Based on all the challenges faced, a strategy was formulated to eliminate TB within the next 5 years by strengthening the leadership of a quality TB service program with a sustainable program across stakeholders

scholarly journals Patients’ perspectives of tuberculosis treatment challenges and barriers to treatment adherence in Ukraine: a qualitative study

BMJ Open ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. e032027 ◽  
Author(s):  
Omowunmi Aibana ◽  
Emily Dauria ◽  
Tetiana Kiriazova ◽  
Olena Makarenko ◽  
Mariya Bachmaha ◽  
...  
Keyword(s):  
Qualitative Study ◽  
Treatment Adherence ◽  
Clinical Sample ◽  
Individual Interviews ◽  
Tb Treatment ◽  
Poor Treatment ◽  
Study Population ◽  
Additional Costs ◽  
Treatment Facilities ◽  
Previously Treated

ObjectivesTo understand the challenges faced by patients with tuberculosis (TB) and factors that influence TB treatment adherence in Ukraine.DesignQualitative study.SettingTB treatment facilities in Kyiv Oblast, Ukraine.ParticipantsSixty adults who had undergone treatment for drug-sensitive TB between June 2012 and August 2015.MethodsWe conducted semistructured, in-depth, individual interviews among a purposively selected clinical sample of patients previously treated for drug-sensitive TB. Interview content encompassed WHO’s framework for barriers to adherence to long-term therapies and included questions about patient preferences and motivators concerning treatment adherence. We examined treatment experience across strata defined by previously identified risk correlates of non-adherence.ResultsAmong 60 participants, 19 (32.8%) were HIV positive, 12 (20.3%) had substance use disorder and 9 (15.0%) had not completed TB treatment. Respondents discussed the psychological distress associated with hospital-based TB care, as well as perceived unsupportive, antagonistic interactions with TB providers as major challenges to treatment adherence. An additional barrier to successful treatment completion included the financial toll of lost income during TB treatment, which was exacerbated by the additional costs of ancillary medications and transportation to ambulatory TB clinics. The high pill burden of TB treatment also undermined adherence. These challenges were endorsed among participants with and without major risk factors for non-adherence.ConclusionsOur findings highlight important barriers to TB treatment adherence in this study population and suggest specific interventions that may be beneficial in mitigating high rates of poor treatment outcomes for TB in Ukraine.

scholarly journals Patient Adherence to Tuberculosis Treatment: A Relation between Family Support and Patient Behavior

2021 ◽  
Vol 10 (2) ◽  
pp. 42
Author(s):  
Rani Putri Haji Soleman ◽  
Tintin Sukartini ◽  
Arina Qona'ah
Keyword(s):  
Family Support ◽  
Treatment Adherence ◽  
Patient Adherence ◽  
Treatment Compliance ◽  
Sampling Technique ◽  
Tuberculosis Treatment ◽  
Cross Sectional ◽  
Patient Behavior ◽  
Control Programs ◽  
Tb Treatment

Introduction: Knowledge, family support, and behavior have a significant impact on an individual's and community's health. They play a critical part in deciding disease control programs and transmission prevention of tuberculosis. The purpose of the study was to determine the association between family support, patient behavior, and tuberculosis treatment compliance in the Baing Primary Health Care of Wulla-Waijilu DistrictMethods:The study design was cross-sectional using the Spearman Rho test. The sample was 123 respondents with purposive sampling technique. The data collection was using sociodemographic questionnaires, family support, behavior, TB treatment adherence and MMAS-8. The dependent variable in this study was family support. The independent variables in this study were patient behavior and TB treatment adherence.Result:There was a relationship between family support and patient behavior (p=0.025), a relationship between family support and compliance with TB treatment (p=0.042)Conclusion:It can be concluded that there was a relationship between family support and TB patient behavior and there was a strong and significant relationship between family support and the level of TB treatment adherence.

scholarly journals Impact of a tuberculosis treatment adherence intervention versus usual care on treatment completion rates: results of a pragmatic cluster randomized controlled trial

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Lisa M. Puchalski Ritchie ◽  
Monique van Lettow ◽  
Austine Makwakwa ◽  
Ester C. Kip ◽  
Sharon E. Straus ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Treatment Adherence ◽  
Health Workers ◽  
Controlled Trial ◽  
Demographic Data ◽  
Treatment Success ◽  
Randomized Controlled ◽  
Tb Treatment ◽  
Adherence Intervention ◽  
Cluster Randomized

Abstract Background With the global shortage of skilled health workers estimated at 7.2 million, outpatient tuberculosis (TB) care is commonly task-shifted to lay health workers (LHWs) in many low- and middle-income countries where the shortages are greatest. While shown to improve access to care and some health outcomes including TB treatment outcomes, lack of training and supervision limit the effectiveness of LHW programs. Our objective was to refine and evaluate an intervention designed to address common causes of non-adherence to TB treatment and LHW knowledge and skills training needs. Methods We employed a pragmatic cluster randomized controlled trial. Participants included 103 health centres (HCs) providing TB care in four districts in Malawi, randomized 1:1 stratified by district and HC funding (Ministry of Health, non-Ministry funded). At intervention HCs, a TB treatment adherence intervention was implemented using educational outreach, a point-of-care reminder tool, and a peer support network. Clusters in the control arm provided usual care. The primary outcome was the proportion of patients with successful TB treatment (i.e., cure or treatment completion). We used a generalized linear mixed model, with district as a fixed effect and HC as a random effect, to compare proportions of patients with treatment success, among the trial arms, with adjustment for baseline differences. Results We randomized 51 HCs to the intervention group and 52 HCs to the control group. Four intervention and six control HCs accrued no eligible patients, and 371 of 1169 patients had missing outcome, HC, or demographic data, which left 74 HCs and 798 patients for analysis. Randomization group was not related to missing outcome, however, district, age, and TB type were significantly related and included in the primary analysis model. Among the 1153 patients with HC and demographic data, 297/605 (49%) and 348/548 (64%) in the intervention and control arms, respectively, had treatment success. The intervention had no significant effect on treatment success (adjusted odds ratio 1.35 [95% confidence interval 0.93–1.98]). Conclusion We found no significant effect of the intervention on TB treatment outcomes with high variability in implementation quality, highlighting important challenges to both scale-up and sustainability. Trial registration ClinicalTrials.gov NCT02533089. Registered August 20, 2015.

scholarly journals Treatment success for patients with tuberculosis receiving care in areas severely affected by Hurricane Matthew – Haiti, 2016

PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0247750
Author(s):  
Macarthur Charles ◽  
Milo Richard ◽  
Mary R. Reichler ◽  
Jean Baptiste Koama ◽  
Willy Morose ◽  
...  
Keyword(s):  
Treatment Success ◽  
Lessons Learned ◽  
Health Facilities ◽  
Hiv Status ◽  
Severe Damage ◽  
Convenience Sample ◽  
Tb Control ◽  
Tb Treatment ◽  
One Year ◽  
The Impact

Background On October 4, 2016, Hurricane Matthew struck southwest Haiti as a category 4 storm. The goal of this study was to evaluate the impact of the hurricane on tuberculosis (TB) services and patient outcomes in the three severely affected departments–Sud, Grand’Anse, and Nippes–of southwest Haiti. Methods We developed a standard questionnaire to assess a convenience sample of health facilities in the affected areas, a patient tracking form, and a line list for tracking all patients with drug-susceptible TB registered in care six months before the hurricane. We analyzed data from the national TB electronic surveillance system to determine outcomes for all patients receiving anti-TB treatment in the affected areas. We used logistic regression analysis to determine factors associated with treatment success. Results Of the 66 health facilities in the three affected departments, we assessed 31, accounting for 536 (45.7%) of 1,174 TB patients registered in care when Hurricane Matthew made landfall in Haiti. Three (9.7%) health facilities sustained moderate to severe damage, whereas 18 (58.1%) were closed for <1 week, and five (16.1%) for ≥1 week. Four weeks after the hurricane, 398 (73.1%) of the 536 patients in the assessed facilities were located. Treatment success in the affected departments one year after the hurricane was 81.4%. Receiving care outside the municipality of residence (adjusted odds ratio [aOR]: 0.46, 95% confidence interval [CI]: 0.27–0.80) and HIV positivity (aOR: 0.31, 95% CI: 0.19–0.51) or unknown HIV status (aOR: 0.49, 95% CI: 0.33–0.74) were associated with significantly lower rates of treatment success. Conclusions Despite major challenges, a high percentage of patients receiving anti-TB treatment before the hurricane were located and successfully treated in southwest Haiti. The lessons learned and results presented here may help inform policies and guidelines in similar settings for effective TB control after a natural disaster.

scholarly journals Treatment outcome monitoring of pulmonary tuberculosis cases notified in France in 2009

2013 ◽  
Vol 18 (12) ◽  
Author(s):  
D Antoine ◽  
D Che
Keyword(s):  
Treatment Outcome ◽  
Treatment Success ◽  
Previous History ◽  
The Elderly ◽  
Successful Outcome ◽  
Unfavourable Outcome ◽  
Tb Control ◽  
Tb Treatment ◽  
Outcome Monitoring ◽  
National Tuberculosis

The proportion of patients considered to be cured is a key indicator to assess national tuberculosis (TB) control. In France, TB treatment outcome monitoring was implemented in 2007. This article presents national results on treatment outcome among patients with pulmonary TB reported in France in 2009 and explores determinants of potentially unfavourable outcome. Information on treatment outcome was reported for 63% of eligible pulmonary cases of whom 70% had a successful outcome. In a multivariate analysis, potentially unfavourable outcome (17%), compared to treatment success, was significantly associated with being male, born abroad and having lived in France for less than 10 years, being in congregate settings when treatment was initiated, or having a previous history of anti-TB treatment. Enhanced awareness of treatment outcome monitoring is essential to improve the coverage and the quality of information. Earlier diagnosis and improved management of the disease in the elderly may reduce death due to TB. The high proportion of potentially unfavourable outcomes should be further investigated as they may require additional vigilance and/or actions in term of efforts of TB control in some population groups.

scholarly journals Analysis of treatment outcome in multi-drug resistant tuberculosis patients treated under programmatic conditions

2017 ◽  
Vol 5 (6) ◽  
pp. 2401 ◽  
Author(s):  
A. K. Janmeja ◽  
Deepak Aggarwal ◽  
Ruchika Dhillon
Keyword(s):  
Treatment Outcome ◽  
Success Rate ◽  
Treatment Adherence ◽  
Treatment Success ◽  
Treatment Practice ◽  
Tb Treatment ◽  
Resistant Tuberculosis ◽  
Multi Drug Resistant Tuberculosis ◽  
Mdr Tb ◽  
Culture Conversion

Background: Programmatic management of MDR-TB has taken over the un-standardized and unsupervised treatment practice in India. However, despite being implemented in whole of country, the data on the program surveillance is scarce.  Hence the present study was sought to evaluate the treatment outcome in patients with MDR TB in Chandigarh being treated under programmatic conditions.Methods: A retrospective study was carried out by enrolling all MDR-TB patients registered between January 2012 to December 2014. Medical records of 140 patients were scrutinized for necessary information on demographic, clinical parameters and previous TB treatment. Treatment outcomes to Cat IV anti-TB therapy, any interruptions in treatment, adverse drug reactions, culture conversion etc. were evaluated from the records.Results: Of the 140 patients, 77 (55%) were declared cured, 11 (7.9%) completed treatment, 23 patients (16.4%) died, 13 (9.3%) defaulted on treatment, 5 (3.6%) had treatment failure and 11 (7.9%) were shifted to Cat V therapy. On comparison, BMI, haemoglobin, treatment outcome in previous ATT, treatment adherence and time to sputum culture conversion were significantly different in different treatment outcome groups.Conclusions: The treatment success rate of MDR‑TB patients have shown improvement under programmatic conditions. Interventions to improve BMI and treatment adherence might further help to improve the success rate.

scholarly journals Tuberculosis Treatment Adherence of Patients in Kosovo

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Shaip Krasniqi ◽  
Arianit Jakupi ◽  
Armond Daci ◽  
Bahri Tigani ◽  
Nora Jupolli-Krasniqi ◽  
...  
Keyword(s):  
Treatment Adherence ◽  
Patient Adherence ◽  
Treatment Success ◽  
Treatment Interruption ◽  
Adherence Rate ◽  
Length Of Treatment ◽  
Tb Treatment ◽  
Poor Patient ◽  
Mdr Tb ◽  
Treatment Prognosis

Setting. The poor patient adherence in tuberculosis (TB) treatment is considered to be one of the most serious challenges which reflect the decrease of treatment success and emerging of the Multidrug Resistance-TB (MDR-TB). To our knowledge, the data about patients’ adherence to anti-TB treatment in our country are missing. Objective. This study was aimed to investigate the anti-TB treatment adherence rate and to identify factors related to eventual nonadherence among Kosovo TB patients. Design. This study was conducted during 12 months, and the survey was a descriptive study using the standardized questionnaires with total 324 patients. Results. The overall nonadherence for TB patient cohort was 14.5%, 95% CI (0.109–0.188). Age and place of residence are shown to have an effect on treatment adherence. Moreover, the knowledge of the treatment prognosis, daily dosage, side effects, and length of treatment also play a role. This was also reflected in knowledge regarding compliance with regular administration of TB drugs, satisfaction with the treatment, interruption of TB therapy, and the professional monitoring in the administration of TB drugs. Conclusion. The level of nonadherence TB treatment in Kosovar patients is not satisfying, and more health care worker’s commitments need to be addressed for improvement.

scholarly journals Prevalence, risk factors and treatment outcomes of isoniazid resistant TB in Bulawayo city, Zimbabwe: A cohort study

2020 ◽  
Vol 14 (08) ◽  
pp. 893-900
Author(s):  
Barbara Manyame-Murwira ◽  
Kudakwashe Collins Takarinda ◽  
Pruthu Thekkur ◽  
Bright Payera ◽  
Herbert Mutunzi ◽  
...  
Keyword(s):  
Cohort Study ◽  
Treatment Outcomes ◽  
Treatment Guidelines ◽  
Reference Laboratory ◽  
Tb Control ◽  
Tb Treatment ◽  
Routinely Collected Data ◽  
Poor Treatment ◽  
Mdr Tb ◽  
Culture Growth

Introduction: The isoniazid-resistant TB poses a threat to TB control efforts. Zimbabwe, one of the high TB burden countries, has not explored the burden of isoniazid resistant TB. Hence among all bacteriologically-confirmed TB patients diagnosed in Bulawayo City during March 2017 and December 2018, we aimed to assess the proportion with isoniazid resistant TB and associated factors. Also, we aimed to describe the TB treatment outcomes. Methodology: A cohort study involving routinely collected data by the National TB Reference Laboratory (NTBRL) in Bulawayo City and National TB programme of Zimbabwe. The percentage with 95% confidence interval (CI) was used to express the proportion with isoniazid-resistant TB. The modified Poisson regression was used to assess the association of demographic and clinical characteristics with isoniazid mono-resistant TB. Results: Of 2160 bacteriologically-confirmed TB patients, 1612 (74.6%) had their sputum received at the NTBRL and 743 (46.1%) had culture growth. Among those with culture growth, 34 (4.6%, 95% CI: 3.5-6.7) had isoniazid mono-resistant TB, 25 (3.3%, 95% CI: 2.2-4.9) had MDR-TB. Thus, 59 (7.9%, 95% CI: 6.1-10.1) had isoniazid-resistant TB. Children < 15 years had a higher prevalence of isoniazid mono-resistant TB (aPR= 3.93; 95% CI: 1.24-12.45). Among those with rifampicin sensitive TB, patients with isoniazid-sensitive TB had higher favourable treatment outcomes compared to those with isoniazid-resistant TB (86.3% versus 75.5%, p = 0.039). Conclusions: The prevalence of isoniazid-resistant TB was low compared to neighbouring countries with high burden of TB-HIV. However, Zimbabwe should consider reviewing treatment guidelines for isoniazid mono-resistant TB due to the observed poor treatment outcomes.

scholarly journals A Randomized Controlled Intervention Trial: Effect of Counselling on Treatment Adherence and Self-Esteem of Women Patients Receiving Tuberculosis Treatment

2016 ◽  
Vol 3 (1) ◽  
pp. 27-33
Author(s):  
Sana Hussain ◽  
Anila A. Malik ◽  
Zareen Hussain
Keyword(s):  
Treatment Adherence ◽  
Group Treatment ◽  
Treatment Success ◽  
Intervention Group ◽  
Self Esteem ◽  
Health Issue ◽  
Public Health Issue ◽  
Control Group ◽  
Tb Treatment ◽  
Before And After

Introduction: Tuberculosis (TB) is considered as a global public health issue but it can be understood as an individual health issue as well. Due to this disease, TB patients not only suffer physically but also psychologically and socially and face severe adverse consequences. Fear of dissemination the illness, helplessness and social stigma related to this ailment, are all plausible causes that lowered self-esteem of the patients and reinforce non-adherence. The purpose of this study was to determine the effect of counselling on treatment adherence and increasing self-esteem of TB patients. Methods: This randomized control trial was conducted in Sindh Government Hospital Karachi. A total of 100 newly diagnosed women TB patients were randomly allocated to intervention (n=50) and control (n=50) groups. The data was collected through demographic form and RSES (Rosenberg Self Esteem Scale). Intervention group received counselling with social support during the treatment while the control group received education at the time of registration. Self-esteem was measured and compared before and after the intervention for two groups. Data was analysed through SPSS by using the χ2, and t-test. Results: Results revealed that compared with control group, treatment success rate was 100% among intervention group. The mean self-esteem scores before and after intervention in the intervention group increased from 10.42 to 17.44 showing a significant statistical difference at p <0.05 and p-value is <0.0001. Conclusion: The result of the present study suggests that patients with higher self-esteem tend to adhere better to TB treatment, in comparison to patients with low self-esteem. Therefore, counselling should be the important component of TB treatment to increase patients’ self-esteem which eventually fosters successful treatment outcomes.

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