scholarly journals Central Retinal Vein Occlusion in a Patient with Retinal Vasculitis and Crohn’s Disease

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Lígia Figueiredo ◽  
Renata Rothwell ◽  
Arnaldo Brandão ◽  
Sofia Fonseca
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Retinal Vein Occlusion ◽  
Central Retinal Vein Occlusion ◽  
Retinal Vasculitis ◽  
Intravitreal Bevacizumab ◽  
Oral Prednisolone ◽  
Vein Occlusion ◽  
The Right ◽  
Central Retinal Vein

The authors report a rare case of a 47-year-old woman with Crohn’s disease (CD) who presented with retinal vasculitis and central retinal vein occlusion (CRVO) during remission. The patient complained of sudden painless visual loss in her left eye (OS). Ophthalmologic evaluation revealed a best corrected visual acuity (BCVA) of 20/20 in the right eye and hand movements in OS. Ophthalmoscopy and fluorescein angiography of OS showed signs of nonischemic CRVO and extensive vasculitis. She was treated with oral prednisolone, mercaptopurine, and intravitreal bevacizumab in OS. After 1 month of treatment, VA of OS improved to 5/10 and after 1 year it was 10/10 with complete resolution of retinal vasculitis and nonischemic CRVO.

scholarly journals Effect Anti VEGF Intravitreal to Central Retinal Vein Occlusion

2018 ◽  
Vol 1 (1) ◽  
pp. 34-41
Author(s):  
Tiara Mayasari ◽  
Ramzi Amin ◽  
AK Ansyori
Keyword(s):  
Retinal Vein Occlusion ◽  
Central Retinal Vein Occlusion ◽  
Intravitreal Bevacizumab ◽  
Central Vein ◽  
Main Complaint ◽  
Vein Occlusion ◽  
Anti Vegf ◽  
Ophthalmologic Examination ◽  
The Right ◽  
Central Retinal Vein

Introduction. The cause of blood vessels abnormalities in the retina in addition to diabetes is obstruction in the veins. In general, retinal vein blockages are distinguished in two types i.e. blockage of retinal veins (BRVO) and obstruction of the central vein of the retina (CRVO). Reported a case of a central retinal vein occlusion with intravitreal anti-injection treatment of a VEGF Bevacizumab. Case presentation. A man, Mr. T, aged 52 years, with an address outside the city, the work of the foreman, came to RSMH's eye on October 2014. Anamnesis the main complaint of the right eye eyesight was suddenly dark since, one day before. One day before go to hospital, the sufferer complained about the right eye suddenly until it felt dark. He also complain often headaches without nausea and vomiting since before his right eye vision becomes blurred. Intravitreal anti-VEGF injection in these patients is planned to be re-done 4-6 weeks after the first injection if there has been no improvement in his vision. Evaluation of the effectiveness of intravitreal Bevacizumab anti-VEGF therapy through sharp improvement of vision, clinical features and anatomical improvement. Conclusion. A case of central retinal vein occlusion was reported in a 52-year-old male. After anamnesis, ophthalmologic examination and investigations, a diagnosis of CRVO is managed by intravitreal Anti VEGF injection.

scholarly journals Detection of Multi-Class Retinal Diseases Using Artificial Intelligence: An Expeditious Learning Using Deep CNN with Minimal Data

2019 ◽  
Vol 12 (3) ◽  
pp. 1577-1586 ◽  
Author(s):  
Karthikeyan S. ◽  
Sanjay Kumar P. ◽  
R J Madhusudan Madhusudan ◽  
S K Sundaramoorthy Sundaramoorthy ◽  
P K Krishnan Namboori3
Keyword(s):  
Real Time ◽  
Retinal Vein Occlusion ◽  
Central Retinal Vein Occlusion ◽  
Research Work ◽  
Diagnostic Strategy ◽  
Fundus Images ◽  
Vein Occlusion ◽  
Deep Cnn ◽  
The Right ◽  
Central Retinal Vein

The health-related complications such as diabetes, macular degeneration, inflammatory conditions, ageing and fungal infections may cause damages to the retina and the macula of the eye, leading to permanent vision loss. The major diseases associated with retina are Arteriosclerotic retinopathy (AR), Central retinal vein occlusion (CRVO), Branch retinal artery occlusion (BRAO), Coat's disease (CD) and Hemi-Central Retinal Vein Occlusion (HRVO). The symptomatic variations among these disorders are relatively confusing so that a systematic diagnostic strategy is difficult to set in. Therefore, an early detection device is required that is capable of differentiating the various ophthalmic complications and thereby helping in providing the right treatment to the patient at the right time. In this research work, 'Deep Convolution Neural Networks (Deep CNN) based machine learning approach has been used for the detection of the twelve major retinal complications from the minimal set of fundus images. The model was further cross-validated with real-time fundus images. The model is found to be superior in its efficiency, specificity and ability to minimize the misclassification. The “multi-class retinal disease” model on further cross-validation with real-time fundus image of the gave an accuracy of 95.63 %, validation accuracy of 92.99 % and F1 score of 91.96 %. The multi-class model is found to be a theranostic clinical support system for the ophthalmologist for diagnosing different kinds of retinal problems, especially BRAO, BRVO, CRAO, CD, DR, HRVO, HP, HR, and CN.

Risk factors for central retinal vein occlusion in young adults

2020 ◽  
pp. 112067212096033
Author(s):  
Tony Y. Chen ◽  
Aditya Uppuluri ◽  
Marco A. Zarbin ◽  
Neelakshi Bhagat
Keyword(s):  
Risk Factors ◽  
Young Adults ◽  
Retinal Vein Occlusion ◽  
Central Retinal Vein Occlusion ◽  
Retinal Vasculitis ◽  
Significant Risk ◽  
Pseudotumor Cerebri ◽  
Vein Occlusion ◽  
Chi Square Analysis ◽  
Central Retinal Vein

Purpose: Several risk factors have been identified for central retinal vein occlusion (CRVO) in older population. CRVO in young is uncommon, and the risk factors for this group are unclear. This large retrospective, cross-sectional study used the National Inpatient Sample (NIS) database to evaluate the risk factors for CRVO in patients 18 to 40 years of age. Methods: The 2002 to 2014 NIS database was used. All patients 18 to 40 years of age with a primary diagnosis of CRVO were identified. Age- and gender-matched non-CRVO controls were randomly selected. The primary outcome was identification of risk factors for CRVO. Chi-square analysis and Firth logistic regression were performed with IBM SPSS 23 and R packages versions 3.4.3, respectively. p < 0.05 was considered significant. Results: A total of 95 weighted young CRVO patients were identified. The average age was 31.44 ± 6.41 years with no gender predilection. Systemic and ocular conditions found to have statistically significant associations with CRVO included primary open-angle glaucoma (POAG) (OR 836.72, p < 0.001), retinal vasculitis (OR 705.82, p < 0.001), pseudotumor cerebri (OR 35.94, p < 0.001), hypercoagulable state (OR 25.25, p < 0.001), history of deep vein thrombosis/pulmonary embolism (DVT/PE) (OR 21.88, p < 0.001), and hyperlipidemia (OR 3.60, p = 0.003). Conclusion: The most significant risk factors for CRVO in young adults were POAG, retinal vasculitis, and pseudotumor cerebri. Hypercoagulable states and DVT/PE were also associated with CRVO in this population. Systemic inflammatory conditions were not associated with CRVO. Traditional risk factors such as hypertension and diabetes did not pose significant risks, whereas hyperlipidemia was deemed a significant risk factor.

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