scholarly journals Comparative Study on the Efficacy of Anorganic Bovine Bone (Bio-Oss) and Nanocrystalline Hydroxyapatite (Ostim) in Maxillary Sinus Floor Augmentation

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Adileh Shirmohammadi ◽  
Leila Roshangar ◽  
Mohammad Taghi Chitsazi ◽  
Reza Pourabbas ◽  
Masoumeh Faramarzie ◽  
...  
Keyword(s):  
Statistical Significance ◽  
Rank Test ◽  
Bovine Bone ◽  
Sinus Augmentation ◽  
Implant Placement ◽  
Nanocrystalline Hydroxyapatite ◽  
Signed Rank Test ◽  
Sinus Floor Augmentation ◽  
Sinus Floor ◽  
The Difference

Purpose. The aim of this study was to evaluate the efficacy of anorganic bovine bone (Bio-Oss) in comparison with nanocrystalline hydroxyapatite (Ostim) in sinus floor augmentation. Methods. Ten patients aged 40–80 were selected. All the patients needed sinus floor augmentation due to insufficient bone for simultaneous implant placement. The patients underwent panoramic radiography and cone beam computed tomography (CBCT) prior to surgical procedure. After lifting the sinus membrane, Bio-Oss and Ostim are randomly grafted at one of the two sides. Biopsies were obtained from areas identified 5 months after the surgery and before implant placement and then were prepared for histological analysis. Statistical analysis was performed with nonparametric Wilcoxon signed-rank test for comparison of histological and radiological parameters between the two groups. Results. Histological findings revealed a significant increase in percentages of new bone in the Ostim group (P=0.015). Furthermore, new bone density was greater with Ostim compared to Bio-Oss (P=0.038); however, the difference in height increase after surgery did not reach statistical significance (P=0.191). Conclusion. Despite the limitations of this trial, Ostim and Bio-Oss are useful biomaterials in sinus augmentation and Ostim seems to be even more effective in new bone formation.

scholarly journals Effects of a periodized functional strength training program (FST) on Functional Movement Screen (FMS) in physical education students

2020 ◽  
Vol 24 (3) ◽  
pp. 162-167
Author(s):  
Michał Sawczyn
Keyword(s):  
Physical Education ◽  
Strength Training ◽  
Statistical Significance ◽  
Rank Test ◽  
Training Intervention ◽  
Control Group ◽  
Before And After ◽  
Signed Rank Test ◽  
The Difference ◽  
Experimental Group

Background and Study Aim: To examine the effects of periodized functional strength training (FST) on FMS scores of sport university students with higher risk of injury. Material and Methods: Thirty three  participants (age 21.6±1.3 years, height 177.8±6.9 m, mass 80.4±7.7 kg) with FMS total score ≤ 14 were selected from eighty two volunteered students of University of Physical Education and Sport in Gdańsk and randomly assigned to experimental group (n=16) and control group (n=17). The FMS test was conducted one week before and one week after the 12 week training intervention. The experimental group participated in FST program through 12 weeks. The control group did not engaged in any additional physical activity than planned in their course of study. The  collected  data  were  analysed  using Statistica 13.3 pl (StatSoft Inc). Wilcoxon signed rank test was used to establish the statistical significance of the difference between FMS total scores within each group and Mann Whitney U test between groups before and after the 12 week training intervention. Results: 45 % of volunteers in the first FMS testing showed total scores ≤14. The experimental group that participated in FST program changed significantly FMS total scores after 12 weeks (p<0.05). There were also significant differences in FMS total score between groups after the experiment (p<0.05). Conclusions: There is a need for injury prevention programs for students of University of Physical Education and Sport in Gdańsk. It is clear from this study that FST is effective in improving FMS total score in students with cut off score ≤14.

Tests for Probability of A Reaction and Difference Between Reactions Where Treatment Increases Marker-Values of Particular Subjects but Decreases Others

2020 ◽  
Author(s):  
Torao Ishida ◽  
Ken Takagi ◽  
Gui-feng Wang ◽  
Nobuyuki Tanahashi ◽  
Jun Kawanokuchi ◽  
...  
Keyword(s):  
Statistical Significance ◽  
T Test ◽  
Rank Test ◽  
Combination Antiretroviral Therapy ◽  
Cd4 Counts ◽  
Paired Samples ◽  
Signed Rank ◽  
Immunodeficiency Virus ◽  
Signed Rank Test ◽  
The Difference

Abstract PD-1 has a role in regulating the response of the immune system to the cells of the human body. Paris et al. reported that combination antiretroviral therapy did not change % CD4+ of PD-1highCTLA-4lowCD127high early/intermediated T cells of human immunodeficiency virus infected patients but increased the percent of the marker limited to initial CD4 counts <200 with Wilcoxon signed-rank test. We hypothesized that the treatment increased the marker value in patients whose initial marker value is less than a particular value and decreased the marker value in other patients and that the test misleadingly concluded that the treatment did not change the marker value. General subgroup analyses correctly estimate the statistical significance of such a reaction or difference between such reactions only when the reaction of both of subgroups or both difference between such subgroups is statistically significant. We propose Ishida’ t-test for paired samples that can correctly judge the probability without division of the group into subgroups, and Ishida’ t-test for unpaired samples that can correctly judge the statistical significance of the difference between such reactions. We also showed that many treatments cause such increase and decrease of marker values relating PD-1 of subjects.

The Influence of Breast Cancer on the Distribution of Cherry Angiomas on the Anterior Thoracic Wall: A Case Series Study

Dermatology ◽  
2018 ◽  
Vol 235 (1) ◽  
pp. 65-70 ◽  
Author(s):  
Antonio Guastafierro ◽  
Vincenzo Verdura ◽  
Bruno Di Pace ◽  
Mario Faenza ◽  
Corrado Rubino
Keyword(s):  
Breast Cancer ◽  
Statistical Significance ◽  
Case Series ◽  
Thoracic Wall ◽  
Rank Test ◽  
P Value ◽  
Unilateral Breast Cancer ◽  
Case Series Study ◽  
Signed Rank Test ◽  
The Difference

Background/Aims: Cherry angiomas (CAs) are one of the most common vascular manifestations of the skin. By and large, these benign lesions often only represent an aesthetic problem. In the literature, few authors have focused on the pathogenesis of these lesions, and some risk factors have been identified, such as the presence of cutaneous and non-skin neoplasias. In this study, the correlation between the distribution of CAs and breast cancer was investigated. Methods: We carried out a study whereby 50 women with unilateral breast cancer and the presence of CAs on the anterior thoracic wall were evaluated, with a particular focus on the difference in the number of CAs between the two haemithoraces. The data was elaborated using the Wilcoxon signed-rank test in order to evaluate whether there was a statistical significance in the distribution of CAs. Results: In 31 patients we found that the number of CAs was greater on the cancerous breast than on the contralateral one (p value <0.0001). This was confirmed both in the group of patients suffering from ductal breast cancer and in the group with early invasive breast tumours. Conclusion: It is not clear whether CAs develop prior to or following breast cancer, indicating the possibility that this cutaneous manifestation could take on a predictive, prognostic development or represent only an epiphenomenon. Further in-depth studies into the pathogenesis of CAs and the relationship with breast cancer could lead to noteworthy diagnostic-therapeutic advances.

scholarly journals Estimating late toxicities based on multivariable NTCP models in patients of high-risk prostate cancer requiring pelvic nodal irradiation: Comparison between Proton beam therapy and helical tomotherapy

2021 ◽  
Author(s):  
Srinivas Chilukuri ◽  
Sham Sundar ◽  
Kartikeswar Patro ◽  
Mayur Sawant ◽  
Rangasamy Sivaraman ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
High Risk ◽  
Helical Tomotherapy ◽  
Statistical Significance ◽  
Proton Beam Therapy ◽  
Matched Pair ◽  
Rank Test ◽  
High Risk Prostate Cancer ◽  
Signed Rank Test ◽  
The Difference

Abstract Purpose:To compare the estimated late gastrointestinal (GI) and genitourinary (GU) toxicities between pencil beam scanning proton bream therapy (PBT) and helical Tomotherapy (HT) in patients of high-risk prostate cancers requiring pelvic nodal irradiation (PNI) using moderate hypo-fractionated regimen.Materials and MethodsTwelve consecutive patients treated with PBT at our centre were re-planned with HT using the same dose prescription and constraints. Late GI and GU toxicities were estimated based on the published NTCP models using clinico-dosimetric parameters. ΔNTCP (difference in absolute NTCP between HT and PBT plans) for each toxicity domains for all patients were calculated. Based on ΔNTCP, model-based selection (MBS) thresholds for PBT were applied on the dataset. One-Sample Kolmogorov-Smirnov test was used to analyze distribution of data and either Paired T-test or Wilcoxon matched-pair signed rank test was used to test statistical significance. ResultsPBT and HT plans achieved adequate target coverage. PBT plans led to significantly better sparing of bladder, rectum and bowel bag especially in the intermediate range of 15-40Gy; whereas doses to penile bulb and femoral heads were higher with PBT plans. The average ΔNTCP for grade(G)2-rectal bleeding, G2-fecal incontinence, G2-stool frequency, G2-dysuria, G2-urinary incontinence and G1-hematuria were 12.17%, 1.67%, 2%, 5.83%, 2.42% and 3.91% respectively favoring PBT plans. The average cumulative ΔNTCP for GI and GU toxicities (ΣΔNTCP) were 16.58% (8.25-24.95; 95% CI) and 11.41%(6.8-16.05) respectively favoring PBT. On applying the MBS threshold of any G2 ΔNTCP >10%, 8 (67%) patients would have qualified for PBT.Conclusion:PBT plans led to superior OAR sparing compared to HT which translated to lower NTCP for late moderate GI and GU toxicities in patients of prostate cancer treated with PNI. For two-thirds of our patients, the difference in estimated absolute NTCP values between PBT and HT, crossed the accepted threshold for minimal clinically important difference.

scholarly journals The Radiographic Management for Surgical Planning and Implant Placement: a Case of Atypical Antral Artery Position

2018 ◽  
Vol 20 (1) ◽  
pp. 8
Author(s):  
Júlio César Schroder ◽  
Ana Paula Tulio Manfron ◽  
Alessandra Soares Ditzel ◽  
Aaron Trujillo ◽  
Angela Deliga Schroder ◽  
...  
Keyword(s):  
Maxillary Sinus ◽  
Surgical Planning ◽  
Cone Beam ◽  
Bleeding Complications ◽  
Radiographic Examination ◽  
Radiographic Evaluation ◽  
Sinus Augmentation ◽  
Implant Placement ◽  
Sinus Floor Augmentation ◽  
Sinus Floor

O conhecimento do suprimento sanguíneo do seio maxilar, em particular da parede lateral, é de considerável importância devido à possibilidade de rompimento acidental de uma artéria durante os procedimento de elevação do assoalho do seio maxilar. Paciente do sexo feminino, 65 anos de idade, com histórico de complicação pós-operatória, após procedimento de elevação do seio maxilar realizado há três anos. Após avaliação tomográfica, foi observada a presença da artéria antral em posição atípica. Identificar e reconhecer essa estrutura anatômica pelo exame radiográfico pré-operatório, evita possíveis complicações hemorrágicas, durante e após o procedimento cirúrgico.Palavras-chave: Tomografia Computadorizada de Feixe Cônico. Seio Maxilar. Procedimentos Cirúrgicos Operatórios.AbstractIt is very important the knowledge of the maxillary sinus blood supply, in particular of the lateral maxillary wall, due to the possibility of accidental rupture of a vessel during the sinus floor augmentation. A case report is described of a 65-year-old female, who reported a postoperative complication after a sinus augmentation that she had had 3 years before. After radiographic evaluation, it was observed the presence of antral artery in atypical position. The identification of this anatomical structure is very important, by preoperative radiographic examination, avoiding possible bleeding complications, during and after the surgical procedures.keywords: Cone-Beam Computed Tomography. Maxillary Sinus. Surgical Procedures, Operative.

scholarly journals Coalescence of inter: Osteotomy bone graft material inserted via separate transcrestal sinus osteotomies: A case report and concise review of the literature

2014 ◽  
Vol 08 (04) ◽  
pp. 553-558 ◽  
Author(s):  
Shane J. J. McCrea
Keyword(s):  
Large Scale ◽  
Progressive Increase ◽  
Bovine Bone ◽  
Graft Material ◽  
Sinus Augmentation ◽  
Radiographic Outcomes ◽  
Sinus Floor Augmentation ◽  
Sinus Floor ◽  
Osteotome Sinus Floor Elevation ◽  
Window Approach

ABSTRACTWhen multiple implants are to be placed, and a pneumatized sinus exists, the published reports suggest that the lateral window approach (LWA) is favored for sinus floor augmentation. Simultaneously, if a transcrestal sinus floor augmentation has been carried out (bone-added osteotome sinus floor elevation), the reports are restricted to single implant placement at any site. The aim of this study was to evaluate the clinical and radiographic outcomes at adjacent transcrestal sinus augmentation grafts using deproteinized bovine bone material, with the immediate placement of submerged adjacent implants, and so determining the fate of the graft material. The progressive loss of the inter-implant graft is reported for the LWA Technique. However, this novel coalescence method has shown a progressive increase in the inter-implant graft region, thus inferring a positive bony regeneration and remodelling at the region. These results indicate that the carrying out of a large scale study is warranted to confirm the efficacy of this technique.

scholarly journals Clinical Outcome of Dental Implants after Maxillary Sinus Augmentation with and without Bone Grafting: A Retrospective Evaluation

Materials ◽  
2021 ◽  
Vol 14 (10) ◽  
pp. 2479
Author(s):  
Gianluca Martino Tartaglia ◽  
Pier Paolo Poli ◽  
Stephen Thaddeus Connelly ◽  
Carlo Maiorana ◽  
Davide Farronato ◽  
...  
Keyword(s):  
Maxillary Sinus ◽  
Alveolar Bone ◽  
Blood Clot ◽  
Survival Rates ◽  
Lateral Sinus ◽  
Sinus Augmentation ◽  
Implant Placement ◽  
Kaplan Meier ◽  
Sinus Floor Augmentation ◽  
Sinus Floor

(1) Background: The purpose of the present study was to retrospectively evaluate and compare the outcome of two sinus augmentation grafting protocols using a xenograft or blood clot alone over a 72-month follow-up. (2) Methods: Patients who received simultaneous lateral sinus floor augmentation and implant placement were included. Subjects were divided into two groups according to the grafting material, namely xenograft or blood clot, and into sub-groups based on the residual alveolar bone height (RABH) below the maxillary sinus, namely 4 to 6 mm or > 6 mm. Kaplan–Meier survival estimates were calculated for each material group and for each sub-group at 1, 3, and 6 years. (3) Results: In total, 289 implants inserted in 136 patients with a one-stage procedure were considered. A total of 35 failures were registered. Overall survival rates were 94.2% for xenograft and 85.9% for blood clot alone at 1 year, 91.1% and 81.6% at 3 years, and 91.1% and 78.7% at 6 years. (4) Conclusions: In patients with 4–6 mm RABH, graftless interventions exploiting blood clot alone were not as successful as those using xenograft. When the RABH is low, sinus floor augmentation associated with grafting materials should be preferred whenever possible.

The Degree of Subjective Complaints of Students Practice in Mechanical Technology Laboratories

2018 ◽  
Vol 4 (1) ◽  
pp. 22
Author(s):  
I Ketut Widana
Keyword(s):  
Engineering Students ◽  
Standing Position ◽  
Statistical Test ◽  
Rank Test ◽  
Cross Sectional ◽  
Signed Rank ◽  
Before And After ◽  
Signed Rank Test ◽  
The Difference ◽  
Paired T Test

The working practice of the engineering students is part of the learning process that is irreducible and indispensable. The composition of  lecturing between theoretical and practical one is 40% to 60%. With this condition, the students spend more time at the laboratory. Generally, the students perform in the laboratory work by standing position. The design of research is observational cross-sectional. The method applied is observation, interview and measuring. The subjects of research are practicing students amounting to 21 students. Referring to the analysis of statistical test or Wilcoxon signed ranks test, the difference of effect of work position is significant, namely p < 0.05 towards musculoskeletal disorders (MSDs) before and after working. The quantity of the average complaint after working is score 44.62 ± 9.47. The result of Wilcoxon signed rank test shows that there is significant different effects of standing work position, namely p < 0.05 towards fatigue generally before and after working. The degree of the working pulse is on the average of 110.78  ± 17.80 bpm (beats per minutes) which can be categorized into the medium workload. Using paired t-test, the result is p < 0.05.

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