scholarly journals Recent Advances in Developing Insect Natural Products as Potential Modern Day Medicines

2014 ◽  
Vol 2014 ◽  
pp. 1-21 ◽  
Author(s):  
Norman Ratcliffe ◽  
Patricia Azambuja ◽  
Cicero Brasileiro Mello
Keyword(s):  
Natural Products ◽  
Antimicrobial Peptides ◽  
Folk Medicine ◽  
Environmental Perturbations ◽  
Recent Advances ◽  
Blood Sucking ◽  
The World ◽  
Problems And Solutions ◽  
Treasure Chest ◽  
Medicinal Drugs

Except for honey as food, and silk for clothing and pollination of plants, people give little thought to the benefits of insects in their lives. This overview briefly describes significant recent advances in developing insect natural products as potential new medicinal drugs. This is an exciting and rapidly expanding new field since insects are hugely variable and have utilised an enormous range of natural products to survive environmental perturbations for 100s of millions of years. There is thus a treasure chest of untapped resources waiting to be discovered. Insects products, such as silk and honey, have already been utilised for thousands of years, and extracts of insects have been produced for use in Folk Medicine around the world, but only with the development of modern molecular and biochemical techniques has it become feasible to manipulate and bioengineer insect natural products into modern medicines. Utilising knowledge gleaned from Insect Folk Medicines, this review describes modern research into bioengineering honey and venom from bees, silk, cantharidin, antimicrobial peptides, and maggot secretions and anticoagulants from blood-sucking insects into medicines. Problems and solutions encountered in these endeavours are described and indicate that the future is bright for new insect derived pharmaceuticals treatments and medicines.

Natural Products: A Rich Source of Antiviral Drug Lead Candidates for the Management of COVID-19

2020 ◽  
Vol 26 ◽  
Author(s):  
Yasanandana Supunsiri Wijayasinghe ◽  
Pravin Bhansali ◽  
Ronald E. Viola ◽  
Mohammad A. Kamal ◽  
Nitesh Kumar Poddar
Keyword(s):  
Natural Products ◽  
Viral Entry ◽  
Folk Medicine ◽  
Antiviral Drug ◽  
Respiratory Illness ◽  
Chemical Diversity ◽  
Viral Proteases ◽  
Drug Lead ◽  
The World ◽  
Novel Coronavirus

: Today, the world is suffering from the pandemic of a novel coronavirus disease (COVID-19), a respiratory illness caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This pandemic is the third fatal coronavirus outbreak that has already occurred in the 21st century. Even six months after its emergence, hundreds of thousands of people are still being infected with SARS-CoV-2, and thousands of lives are lost every day across the world. No effective therapy has been approved to date for the prevention or treatment of this disease, suggesting the need to broaden the scope in the search for effective treatments. Throughout history, folk medicine has been successfully used to treat various ailments in humans and Traditional Chinese Medicine has been instrumental in the containment of a number of viral diseases. Owing to their high chemical diversity and safety profiles, natural products offer great promises as potentially effective antiviral drugs. In recent years, a large number of anti-coronaviral phytochemicals with different mechanisms of action have been identified. Among them, tetra-O-galloyl-β-D-glucose, caffeic acid, and saikosaponin B2 block viral entry. A number of flavonoids inhibit viral proteases. Silvestrol inhibits protein synthesis. Myricetin and scutellarein inhibit viral replication. Emodin, luteolin, and quercetin demonstrate anti-coronaviral activity by inhibiting multiple processes in the virus life cycle. In this review, we critically evaluate the findings of the natural product-based anti-coronaviral research that has been published during last two decades, and attempt to provide a comprehensive description about their utility as potential broad-spectrum anti-coronaviral drugs, examining leads that may guide/facilitate anti-SARS-CoV-2 drug development studies.

Nigella Sativa: An immunity booster as pandemic treatment solution against SARS-CoV-2

Coronaviruses ◽  
2020 ◽  
Vol 01 ◽  
Author(s):  
Afzal Hussain ◽  
Ashfaq Hussain ◽  
Chandan Kumar Verma
Keyword(s):  
Medicinal Plant ◽  
Therapeutic Efficacy ◽  
Nigella Sativa ◽  
Folk Medicine ◽  
The World ◽  
Immune Booster

: Nigella sativa (Family Ranunculaceae) is a common medicinal plant all across the world. It is quite popular in different traditional medicinal systems such as Unani, Ayurveda, Tibb, and Siddha. Oil and Seeds have a long tradition of folk medicine utilized in different medicinal systems and food. The seeds of N. Sativa have indeed been widely applied in the treatment of many diseases, ailments, and also the immune booster. Our goal primarily concentrated on the therapeutic efficacy of Nigella sativa in combating the COVID-19 pandemic.

Interactive Visual Ideas for Musical Classroom Activities

2020 ◽  
Author(s):  
Catherine Dwinal
Keyword(s):  
Streaming Media ◽  
Digital Tools ◽  
Tips And Tricks ◽  
Classroom Activities ◽  
Digital World ◽  
Resource Index ◽  
The World ◽  
Music Venues ◽  
Treasure Chest

This book is a resource on projection systems for any music teacher’s treasure chest of tools. Educators, from brand new to seasoned veterans, can discover new lessons, activities, and resources involving the projection systems already in their classrooms. From conventional projectors to streaming media players, beginners to the digital world will find tips and tricks to start using new systems. More experienced users will discover new resources and activities, from learning how to create VR worlds to demonstrate knowledge of music venues from around the world, to going on an outside safari to find missing instruments of the orchestra. This book also includes a resource index with app and website recommendations for going further and appendices that make it easier to find the activities and resources to fit any type of instruction. This book is a toolbox for teachers to keep on their desks to use every day to incorporate their digital tools in a meaningful way.

scholarly journals A Comprehensive Review of the Ethnotraditional Uses and Biological and Pharmacological Potential of the Genus Mimosa

2021 ◽  
Vol 22 (14) ◽  
pp. 7463
Author(s):  
Ismat Majeed ◽  
Komal Rizwan ◽  
Ambreen Ashar ◽  
Tahir Rasheed ◽  
Ryszard Amarowicz ◽  
...  
Keyword(s):  
Web Of Science ◽  
Scientific Literature ◽  
Therapeutic Potential ◽  
Current Knowledge ◽  
Folk Medicine ◽  
Nutritional Values ◽  
Biological Potential ◽  
The World ◽  
The Future ◽  
Pharmacological Potential

The Mimosa genus belongs to the Fabaceae family of legumes and consists of about 400 species distributed all over the world. The growth forms of plants belonging to the Mimosa genus range from herbs to trees. Several species of this genus play important roles in folk medicine. In this review, we aimed to present the current knowledge of the ethnogeographical distribution, ethnotraditional uses, nutritional values, pharmaceutical potential, and toxicity of the genus Mimosa to facilitate the exploitation of its therapeutic potential for the treatment of human ailments. The present paper consists of a systematic overview of the scientific literature relating to the genus Mimosa published between 1931 and 2020, which was achieved by consulting various databases (Science Direct, Francis and Taylor, Scopus, Google Scholar, PubMed, SciELO, Web of Science, SciFinder, Wiley, Springer, Google, The Plant Database). More than 160 research articles were included in this review regarding the Mimosa genus. Mimosa species are nutritionally very important and several species are used as feed for different varieties of chickens. Studies regarding their biological potential have shown that species of the Mimosa genus have promising pharmacological properties, including antimicrobial, antioxidant, anticancer, antidiabetic, wound-healing, hypolipidemic, anti-inflammatory, hepatoprotective, antinociceptive, antiepileptic, neuropharmacological, toxicological, antiallergic, antihyperurisemic, larvicidal, antiparasitic, molluscicidal, antimutagenic, genotoxic, teratogenic, antispasmolytic, antiviral, and antivenom activities. The findings regarding the genus Mimosa suggest that this genus could be the future of the medicinal industry for the treatment of various diseases, although in the future more research should be carried out to explore its ethnopharmacological, toxicological, and nutritional attributes.

ChemInform Abstract: Recent Advances in the Synthesis of Cyclic Polyether Marine Natural Products

ChemInform ◽  
2010 ◽  
Vol 30 (21) ◽  
pp. no-no
Author(s):  
K. C. Nicolaou ◽  
M. H. D. Postema ◽  
N. D. Miller
Keyword(s):  
Natural Products ◽  
Marine Natural Products ◽  
Recent Advances

Recent advances in anti-HIV natural products

2010 ◽  
Vol 27 (12) ◽  
pp. 1781 ◽  
Author(s):  
Inder Pal Singh ◽  
Hardik S. Bodiwala
Keyword(s):  
Natural Products ◽  
Recent Advances ◽  
Anti Hiv

Recent Advances in Script Identification

2014 ◽  
Vol 610 ◽  
pp. 734-740
Author(s):  
Kurban Ubul ◽  
Gulzira Tursun ◽  
Alim Aysa
Keyword(s):  
Classification Methods ◽  
Script Identification ◽  
Recent Advances ◽  
The World

There are a variety of different scripts in the world. Almost every country have there own languages and scripts which can distinguish from each other in different aspects. It is very essential to identify different scripts in multi-lingual, multi-script document. In recent years, different kinds of approaches have been developed for script identification and gotten promising results. In this paper, an overview of the script identification is proposed under different categories: script systems, extracted features and classification methods. Earlier researches and future property of this field is discussed. It is very obvious that, the research in this area is not so satisfied and still more research is to be done.

scholarly journals At the Edge of Knowability: Towards a Prehistory of Languages

2000 ◽  
Vol 10 (1) ◽  
pp. 7-34 ◽  
Author(s):  
Colin Renfrew
Keyword(s):  
Molecular Genetics ◽  
Late Pleistocene ◽  
Historical Linguistics ◽  
Prehistoric Archaeology ◽  
Recent Advances ◽  
New Synthesis ◽  
The World ◽  
Pleistocene Period ◽  
Demographic Processes

The issue of ‘knowability’ in relation to the origins and distribution of the language families of the world is addressed, and recent advances in historical linguistics and molecular genetics reviewed. While the much-debated problem of the validity of the concept of the language ‘macrofamily’ cannot yet be resolved, it is argued that a time depth for the origins of language families greater than the conventional received figure of c. 6000 years may in some cases be appropriate, allowing the possibility of a correlation between language dispersals and demographic processes following the end of the Pleistocene period. The effects of these processes may still be visible in the linguistic ‘spread zones’, here seen as often the result of farming dispersals, contrasting with the linguistic ‘mosaic zones’ whose early origins may sometimes go back to initial colonization episodes during the late Pleistocene period. If further work in historical linguistics as well as in archaeology and molecular genetics upholds these correlations a ‘new synthesis’, whose outlines may already be discerned, is likely to emerge. This would have important consequences for prehistoric archaeology, and would be of interest also to historical linguists and molecular geneticists. If, however, the proposed recognition of such patterning proves illusory the prospects for ‘knowability’ appear to be less favourable.

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