scholarly journals Neurobiological Mechanisms of Pelvic Pain

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Massimo Origoni ◽  
Umberto Leone Roberti Maggiore ◽  
Stefano Salvatore ◽  
Massimo Candiani
Keyword(s):  
Pelvic Pain ◽  
Neural Plasticity ◽  
Health Care Professionals ◽  
Pain Perception ◽  
Common Condition ◽  
Visceral Systems ◽  
Related Quality ◽  
Health Related ◽  
Complex Circuits

Pelvic pain is a common condition which significantly deteriorates health-related quality of life. The most commonly identified causes of pain in the pelvic region are gynaecologic, urologic, gastrointestinal, neurological, and musculoskeletal. However, in up to 33% of patients the source of this symptom is not identified, frustrating both patients and health-care professionals. Pelvic pain may involve both the somatic and visceral systems, making the differential diagnosing challenging. This paper aimed to review the mechanisms involved in pelvic pain perception by analyzing the neural plasticity and molecules which are involved in these complex circuits.

Overview of microscopic colitis

2020 ◽  
Vol 81 (10) ◽  
pp. 1-7
Author(s):  
Omer F Ahmad ◽  
Ayesha Akbar
Keyword(s):  
Selective Serotonin Reuptake Inhibitors ◽  
Symptom Control ◽  
Microscopic Colitis ◽  
Common Condition ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Rising Incidence ◽  
Inflammatory Drugs

Microscopic colitis encompasses both collagenous and lymphocytic colitis and is a relatively common condition with rising incidence. Diagnosis is by colonoscopy (which is usually normal but may show some mild changes) and biopsies which reveal characteristic histological findings. Symptoms include non-bloody diarrhoea with urgency which may be associated with faecal incontinence and abdominal pain. Microscopic colitis is associated with a reduced health-related quality of life, and treatment is aimed at symptom control. Medications linked with the development of microscopic colitis, including proton pump inhibitors, non-steroidal anti-inflammatory drugs and selective serotonin-reuptake inhibitors, should be discontinued. If symptoms persist, budesonide is a licensed treatment for microscopic colitis which has been shown to be effective in clinical trials and real-world practice.

scholarly journals Quality of sleep and health-related quality of life among health care professionals treating patients with coronavirus disease-19

2020 ◽  
pp. 002076402094280 ◽  
Author(s):  
Jelena Stojanov ◽  
Marina Malobabic ◽  
Goran Stanojevic ◽  
Milos Stevic ◽  
Vuk Milosevic ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Health Care ◽  
Mental Status ◽  
Health Care Professionals ◽  
Short Form ◽  
Health Related Quality ◽  
Quality Of Sleep ◽  
Related Quality ◽  
Health Related

Background: Health care professionals exposed to coronavirus disease 2019 (COVID-19) are facing high levels of stress. Aim: The aim was to evaluate the quality of sleep (QoS) and health-related quality of life (HRQoL), among health care professionals treating patients with COVID-19, as well as quantifying the magnitude of symptoms of depression and levels of anxiety. Methods: We included 201 health care professionals in a cross-sectional, web-based study by applying 7-item Generalized Anxiety Disorder (GAD-7) Scale, Zung Self-rating Depression Scale, 36-item Health Survey of the Medical Outcomes Study Short Form (SF36), Pittsburgh Sleep Quality Index (PSQI) and additional survey constructed for the purpose of the study. Results: Health care workers who treated COVID-19 patients were more afraid of becoming infected or of transmitting the infection to a family member with a significantly low self-assessment of their mental status. Poor QoS and HRQoL correlated with high health anxiety and severe depressive symptoms and several demographic characteristics. Multiple linear regression analysis showed that higher scores on GAD-7 (beta = .71, p < .01) and lower scores on mental health (MH) subscale on SF36 questionnaire (beta = –.69; p < .01) were independent predictors of the higher PSQI score (adjusted R2 = .61, p < .01 for overall model). Higher scores on GAD-7 (beta = .68, p < .01) and worse self-perceived mental status (beta = .25; p < .05) were independent predictors of the lower SF36 scores (adjusted R2 = .73, p < .01 for overall model). Conclusion: The major MH burden of health care professionals treating infected patients during the COVID-19 pandemic indicates that they need psychological support.

scholarly journals Outcome, Pain Perception, and Health-Related Quality of Life in Patients Submitted to Percutaneous Ethanol Injection for Simple Thyroid Cysts

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Roberto Negro ◽  
Ermenegildo Colosimo ◽  
Gabriele Greco
Keyword(s):  
Quality Of Life ◽  
Pain Perception ◽  
Percutaneous Ethanol Injection ◽  
Cystic Lesions ◽  
Health Related Quality ◽  
Effective Technique ◽  
Ethanol Injection ◽  
Related Quality ◽  
Health Related

Thyroid cysts are usually benign lesions that when voluminous may induce cosmetic concerns or local discomfort. Percutaneous ethanol injection (PEI) has been demonstrated to be effective for shrinkage of such cysts. In this retrospective study, we evaluated the efficacy, pain perception, and health-related quality of life (HRQL) in patients submitted to PEI for pure cystic lesions. We reviewed the data of 101 patients who underwent ≤3 PEI. In the whole group of patients, the volume reduction was 66% after the first, 74.4% after the second, and 79.4% after the third PEI treatment. 55.4% had a cystic volume ≤ 10 ml; 85.7% of cysts ≤ 10 ml were cured by just one PEI. The number of PEI was significantly higher in the >30.0 ml group; this latter group obtained the smallest percent reduction versus baseline after the first PEI when compared with smaller cysts. The sensation of pain reported during PEI was absent in 78.3% of cases, and HRQL significantly improved from pre- to the posttreatment. PEI is a safe and effective technique for pure cystic lesions. In addition, HRQL significantly improves, providing a further support for this procedure.

Self-Efficacy and Health-Related Quality of Life Among Heart Failure Patients in Singapore: A Descriptive Correlational Study

2017 ◽  
Vol 29 (4) ◽  
pp. 326-334 ◽  
Author(s):  
Rajasekaram Suresh ◽  
Wenru Wang ◽  
Karen W. L. Koh ◽  
Shefaly Shorey ◽  
Violeta Lopez
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Health Care Professionals ◽  
Self Efficacy ◽  
Smoking Status ◽  
Health Related Quality ◽  
Education Levels ◽  
Related Quality ◽  
Health Related

Introduction: Heart failure (HF) accounts for 30% of all global deaths and Asians are likely to suffer from HF 10 years earlier than their Western counterparts. Low self-efficacy and poor health-related quality of life (HRQoL) have been reported in patients with HF. Methodology: A descriptive correlational design was adopted to investigate the associations between self-efficacy and HRQoL in 91 patients with HF in Singapore. Results: Patients with HF demonstrated moderately good self-efficacy ( M = 3.05, SD = 0.61) and HRQoL ( M = 22.48, SD = 18.99). Significant differences were found between total self-efficacy scores and education levels ( p = .05), and between overall HRQoL and smoking status ( p < .05). Self-efficacy was not significantly correlated to HRQoL. Smoking status, HF classification, and self-efficacy in maintaining function predicted HRQoL. Discussion: Health care professionals should assess each patient’s demographics, smoking status, and clinical condition before delivering individualized education to enhance their self-efficacy and, in turn, overall HRQoL.

scholarly journals Gynaecological issues in women with bleeding disorders: CSL Behring Symposium

2019 ◽  
Vol 6 (2) ◽  
pp. 28-38
Author(s):  
Angelika Batorova ◽  
Karin van Galen ◽  
Sylvia von Mackensen ◽  
Ioannis Tsimpanakos ◽  
Evelyn Grimberg
Keyword(s):  
Quality Of Life ◽  
Pelvic Pain ◽  
Successful Outcome ◽  
Severe Bleeding ◽  
Bleeding Tendency ◽  
Bleeding Disorders ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Abstract The symposium focused on issues around surgery, ovulation bleeding, health-related quality of life (HRQoL) and pelvic pain in women with bleeding disorders. Surgery Young women with congenital bleeding disorders, especially those with severe forms, are more likely to experience gynaecological and obstetric disorders than unaffected women. Surgery may be required to manage heavy menstrual bleeding (HMB), ovulatory bleeding, endometriosis and delivery. Major surgery should be undertaken only in hospitals with a haemophilia centre and 24-hour laboratory capability. Correction of haemostasis, either by desmopressin, coagulation factor or platelet transfusion, is essential for a successful outcome of surgery. Management of pregnancy requires a multidisciplinary approach; the mode of delivery is based on the consensus of gynaecologist and haematologist, and with respect to the patient’s diagnosis. Ovulation bleeding Women with bleeding disorders are at risk for excessive gynaecological bleeding associated with menstruation, ovulation, pregnancy and delivery. Ovulation bleeding is associated with the rupture of ovarian cysts and causes abdominal pain; complications include haemoperitoneum, fertility problems and ovarian torsion. Management includes hormonal and haemostatic therapies, in combination if necessary, and surgery as a last resort. Current management is based on experience in a relatively small number of cases and more clinical data are needed. Health-related quality of life In addition to experiencing joint and tissue bleeds, women experience psychosocial and medical issues associated with menstruation, pregnancy, labour and delivery. HMB has the greatest impact, and is associated with impaired HRQoL in almost all and dissatisfaction with the burden of treatment. There is a need for focused psychosocial support and a specific tool for the assessment of HRQoL in women with bleeding disorders. Pelvic pain Gynaecological causes of pelvic pain in women with bleeding disorders include dysmenorrhoea, mid-cycle pain, bleeding into the corpus luteum and endometriosis. There is no correlation between bleeding tendency and endometriosis severity; however, screening for a bleeding disorder should be considered. Pharmacological management may be hormonal or non-hormonal. Gonadotrophin-releasing hormone agonists offer an alternative to surgery for women with severe bleeding disorders who have endometriosis. Paracetamol is the preferred early analgesic option. Endometrial ablation controls heavy bleeding and pelvic pain but is not recommended for women with large fibroids or a large endometrial cavity. Hysterectomy is an option of last resort. Education for health professionals should include raising awareness about the management of pain in women with bleeding disorders.

scholarly journals Sense of Coherence and Caregivers of Persons with Dementia

2019 ◽  
Vol 9 (2) ◽  
pp. 14 ◽  
Author(s):  
Kristina Childers
Keyword(s):  
Sense Of Coherence ◽  
Health Care Professionals ◽  
Stress Coping ◽  
Consistent Theory ◽  
Large Samples ◽  
Clinical Observations ◽  
Current State ◽  
Related Quality ◽  
Health Related

Unpaid caregivers (CG) provide most of the assistance to persons with dementias (PWD) living in the community. This study explores the current state of knowledge regarding the concept of sense of coherence (SOC) and CG of PWD via a concept analysis. The identified defining attributes were health, health-related quality of life (HRQoL), CG burden, CG stress, coping as a strength, gender, and decreasing sense of CG coherence over the progression of the disease (dementia). Further study by health care professionals using clinical observations, large samples of respondents, a consistent theory, valid and reliable instruments used to measure defining attributes consistently, and critical reviews of the literature are needed.

scholarly journals Cognitive impact of lower grade gliomas and strategies for rehabilitation

2020 ◽  
Author(s):  
Christina Weyer-Jamora ◽  
Melissa S Brie ◽  
Tracy L Luks ◽  
Ellen M Smith ◽  
Steve E Braunstein ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Neural Plasticity ◽  
Cognitive Rehabilitation ◽  
Tumor Location ◽  
Lower Grade ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Rehabilitation Strategies

Abstract Outcomes for patients with lower grade gliomas (LrGG) continue to improve with advances in molecular characterization and treatment. However, cognitive sequela from the tumor and its treatment leave a significant impact on health related quality of life for these patients. Several factors affect each patient’s cognition, such as tumor location, treatment, medication, and co-morbidities. However, impairments of processing speed, attention, concentration, working memory, and executive function are common across LrGG patients. Cognitive rehabilitation strategies, well established in traumatic brain injury and stroke populations, are based on neural plasticity and functional reorganization. Adapting these strategies for implementation in patients with brain tumors is an active area of research. This article provides an overview of cognitive domains commonly impaired in LrGG patients and evidence for the use of cognitive rehabilitation strategies to address these impairments with the goal of improving health related quality of life in this patient population.

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