scholarly journals Aspiration Pneumonitis Caused by Polyethylene Glycol-Electrolyte Solution Treated with Conservative Management

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Ricardo A. Mosquera ◽  
Mark McDonald ◽  
Cheryl Samuels
Keyword(s):  
Polyethylene Glycol ◽  
Electrolyte Solution ◽  
Case Reports ◽  
Aspiration Pneumonitis ◽  
Close Monitoring ◽  
Solution Treated ◽  
Toxic Material ◽  
Bowel Cleansing ◽  
Accidental Infusion ◽  
Osmotic Laxative

Polyethylene glycol (PEG) electrolyte solution, Golytely, is an osmotic laxative commonly used in preoperative bowel cleansing. In this case report, a 9-year-old boy developed aspiration pneumonitis following accidental infusion of PEG solution into his right lung following migration of his nasogastric tube (NGT). Hypoxemia and tachypnea without respiratory failure were observed after infusion. Because PEG is a nonabsorbable toxic material, previous case reports have advocated for the performance of bronchoalveolar lavage (BAL) in the treatment of PEG pneumonitis. With close monitoring, our patient was able to be successfully treated without the need for invasive interventions including BAL or intubation. Generalizations about PEG absorption in the lung based on its permeability in the gastrointestinal tract should not deter the use of more conservative treatment in the appropriate patient.

scholarly journals Administering Polyethylene Glycol Electrolyte Solution Via a Nasogastric Tube: Pulmonary Complications

2017 ◽  
Vol 26 (2) ◽  
pp. e11-e17 ◽  
Author(s):  
Norma A. Metheny ◽  
Kathleen L. Meert
Keyword(s):  
Polyethylene Glycol ◽  
Electrolyte Solution ◽  
Large Volume ◽  
Nasogastric Tube ◽  
Case Reports ◽  
Pulmonary Complications ◽  
Tube Placement ◽  
Patients Âgés ◽  
Serious Injury ◽  
The Cost

Background Patients sometimes require insertion of a nasogastric tube for the administration of a large volume of a polyethylene glycol electrolyte solution. If the tube is malpositioned, the risk for direct instillation of the solution into the lung increases. The risk for aspiration also increases if the infusion rate exceeds gastrointestinal tolerance. Purpose To review published cases of patients’ experiencing adverse pulmonary events after administration of polyethylene glycol electrolyte solution via a nasogastric tube and to offer suggestions to prevent these outcomes. Methods A search of the literature from 1993 through 2014 was performed by using the PubMed, MEDLINE, Cumulative Index to Nursing and Allied Health Literature, and Scopus databases. Results In the 12 case reports located, none of the patients had radiographs to verify tube location before infusion of polyethylene glycol electrolyte solution. After symptoms developed in 3 children (ages 8–11 years), radiographs showed their tubes incorrectly positioned in the bronchus, lung, or esophagus; ports of a fourth child’s tube were in the oropharynx. The remaining 8 patients (ages 5–86 years) never had radiographs to determine tube placement. Pulmonary complications from the infusions of polyethylene glycol electrolyte solution contributed to the death of 5 of the patients. Conclusion Relatively simple maneuvers to reduce the likelihood of adverse pulmonary events following the administration of large volumes of polyethylene glycol electrolyte solution via a nasogastric tube are well worth the cost and effort to protect patients from potential serious injury.

Sugar-free menthol candy drops improve the palatability and bowel cleansing effect of polyethylene glycol electrolyte solution

2013 ◽  
Vol 78 (6) ◽  
pp. 886-891 ◽  
Author(s):  
Ala I. Sharara ◽  
Mustapha M. El-Halabi ◽  
Carla G. Abou Fadel ◽  
Fayez S. Sarkis
Keyword(s):  
Polyethylene Glycol ◽  
Electrolyte Solution ◽  
Bowel Cleansing

Sa1101 Magnesium Sulphate Versus Polyethylene Glycol for Bowel Cleansing Prior to Colonoscopy: A Prospective Randomized Endoscopist-Blinded Trial

2017 ◽  
Vol 85 (5) ◽  
pp. AB191
Author(s):  
Kayalvizhi Nagarajan ◽  
Pradeep Kakkadasam Ramaswamy ◽  
Amit Yelsangikar ◽  
Anupama Nagar ◽  
Naresh Bhat
Keyword(s):  
Polyethylene Glycol ◽  
Magnesium Sulphate ◽  
Bowel Cleansing ◽  
Blinded Trial

scholarly journals Low-residue breakfast during the preparation for colonoscopy using a polyethylene glycol electrolyte solution: a randomised non-inferiority trial

2015 ◽  
Vol 2 (1) ◽  
pp. e000029 ◽  
Author(s):  
Jennifer A Flemming ◽  
Jordan Green ◽  
Andrea Melicharkova ◽  
Stephen Vanner ◽  
Lawrence Hookey
Keyword(s):  
Polyethylene Glycol ◽  
Electrolyte Solution
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