scholarly journals Maintenance of Increased Mouth Opening in Oral Submucous Fibrosis Patient Treated with Nasolabial Flap Technique

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Milind Naphade ◽  
Bhushan Bhagat ◽  
Dwarkadas Adwani ◽  
Ranjit Mandwe
Keyword(s):  
Chronic Disease ◽  
Oral Cavity ◽  
Oral Mucosa ◽  
Oral Submucous Fibrosis ◽  
Mouth Opening ◽  
Oral Carcinoma ◽  
Nasolabial Flap ◽  
Flap Technique ◽  
Submucous Fibrosis ◽  
Malignant Changes

Oral submucous fibrosis (OSMF) is an insidious chronic disease affecting any part of the oral cavity and sometimes the pharynx with epithelial atrophy leading to stiffness of the oral mucosa, causing trismus and inability to eat. However, a more serious complication of this disease is the risk of the development of oral carcinoma. A case of OSMF reported with initial interincisal mouth opening; 8 mm which was treated surgically with nasolabial flap technique followed by active mouth opening exercises for 6 months with Hister’s jaw exerciser. The patient could maintain mouth opening of 32 mm at the end of 18-months followup. The patient was observed closely for any malignant changes in the oral cavity.

scholarly journals Nasolabial Flap in the Management of Oral Submucous Fibrosis

2016 ◽  
Vol 1 (1) ◽  
pp. 27-29
Author(s):  
Vaishali Jamdade ◽  
Amit LNU
Keyword(s):  
Surgical Treatment ◽  
Physical Therapy ◽  
Oral Submucous Fibrosis ◽  
Mouth Opening ◽  
Oral Carcinoma ◽  
Treatment Modalities ◽  
Nasolabial Flap ◽  
Mahatma Gandhi ◽  
Premalignant Condition ◽  
Submucous Fibrosis

ABSTRACT Oral submucous fibrosis (OSMF) is a premalignant condition associated with restricted mouth opening. Oral submucous fibrosis is poorly understood and unsatisfactorily treated disease. Serious complication is the risk of development of oral carcinoma. Different treatment modalities like medical, surgical, physical therapy or combination are used to improve the condition of the patient. Surgical treatment is usually indicated in late and irreversible stage of the disease. Successful use of nasolabial flap in the management of OSMF is presented. How to cite this article Jamdade V, Sharma S, Chitlangia P, Amit. Nasolabial Flap in the Management of Oral Submucous Fibrosis. J Mahatma Gandhi Univ Med Sci Tech 2016;1(1):27-29.

scholarly journals Comparative Study of Intralesional Dexamethasone Plus Hyaluronidase & Oral Colchicine in Patients with Oral Submucous Fibrosis

2018 ◽  
Vol 14 (2) ◽  
pp. 60-65
Author(s):  
Ganesh Prasad Neupane ◽  
Maya Rai ◽  
R. S. Rathore ◽  
V. K. Bhargava ◽  
A. K. Mahat ◽  
...  
Keyword(s):  
Treatment Outcomes ◽  
Oral Mucosa ◽  
Oral Submucous Fibrosis ◽  
Mouth Opening ◽  
Study Groups ◽  
T Test ◽  
Significant Difference ◽  
Intralesional Injections ◽  
Submucous Fibrosis ◽  
Larger Sample

Introduction: Oral Submucous Fibrosis (OSMF) is a precancerous condition of the oral mucosa. It is characterized by excessive production of collagen leading to inelasticity of the oral mucosa and atrophic changes of the epithelium.Aim and objective: To evaluate the efficacy of oral Colchicine in comparison to intralesional injections of Dexamethasone plus Hyaluronidase in the management of OSMF patients.Materials and Methods: Fourty patients with OSMF were randomly divided equally into two groups. 20 patients in Dexamethasone group received biweekly intralesional injections of Dexamethasone (4mg/ml) plus Hyaluronidase 1500 IU in buccal mucosa for a period of 12 weeks. Other 20 patients in Colchicine group received oral Colchicine 0.5 mg tablets twice daily for 12 weeks. Parameters taken in the study were burning sensation, and mouth opening. Descriptive statistics, paired t test and unpaired t test were used for statistical analysis.Results and Conclusions: The pre- and post-treatment differences were found to be statistically significant for both the groups (p<0.001) and for both the treatment outcomes. When the average difference of the treatment outcomes was compared between the two study groups, statistically highly significant difference was noted (p <0.001) only in mouth opening but not in burning sensation.These encouraging results should prompt further clinical trials with Colchicine on a larger sample size to broaden the therapeutic usefulness of the drug in the management of OSMF. JNGMC,  Vol. 14 No. 2 December 2016, Page: 60-65

scholarly journals Hearing Efficiency in Oral Submucous Fibrosis: A Clinical Study

2020 ◽  
Author(s):  
J. S. Shah ◽  
Nutan Lunagariya
Keyword(s):  
Oral Mucosa ◽  
Conductive Hearing Loss ◽  
Oral Submucous Fibrosis ◽  
Hearing Threshold ◽  
Mouth Opening ◽  
Burning Sensation ◽  
Areca Nut ◽  
Gradual Reduction ◽  
Submucous Fibrosis ◽  
Conductive Hearing

Abstract Oral Submucous fibrosis (OSMF) is a chronic insidious disease of oral mucosa that occurs due to areca-nut chewing, consumption of chillies, autoimmunity and genetic predisposition. The disease starts with burning sensation and inability to tolerate spicy foods with gradual reduction in mouth opening due to fibrosis of the oral mucosa. The extension of fibrosis into the naso pharynx leads to reduction in hearing efficiency. As very few studies had been done to evaluate the hearing disability in OSMF patients, this study had been undertaken to prove the same. To evaluate hearing efficiency in patients with Oral Submucous Fibrosis of various grades of severity. Presentation includes 30 patients of osmf with various grades and evaluated for hearing efficacy by audiometry. Hearing threshold was compared in different grades of osmf. The present study revealed a significant association between OSMF and hearing deficit. Involvement of the palatal muscles with OSMF may decrease the patency of the Eustachian tube, leading to conductive hearing loss. Therefore, the protocol for managing OSMF patients should include ENT consultation and treatment for hearing deficit in order to increase the success rate of treatment.

Oral Submucous Fibrosis—treatment with hyalase

1985 ◽  
Vol 99 (1) ◽  
pp. 57-60 ◽  
Author(s):  
P. K. Kakar ◽  
R. K. Puri ◽  
V. P. Venkatachalam
Keyword(s):  
Chronic Disease ◽  
Connective Tissue ◽  
Oral Cavity ◽  
Oral Submucous Fibrosis ◽  
Unknown Etiology ◽  
Vesicle Formation ◽  
The Past ◽  
Oral Mucous Membrane ◽  
Submucous Fibrosis ◽  
Placental Extract

AbstractOral Submucous Fibrosis (OSMF) is a disease of unknown etiology. A total of 96 patients with Oral Submucous Fibrosis have received four regimens of treatment–local dexamethasone, local hyaluronidase, local combination of dexamethasone and hyaluronidase, and local placental extract. The patients were followed up for a period varying from 3 months to 2 years. The group of patients receiving hyaluronidase alone showed quicker improvement in symptoms although its combination with dexamethasone gave somewhat better longer-term results. A new regimen for the treatment of submucous fibrosis is recommended.Oral Submucous Fibrosis is a well-known clinical entity, known since the time of Sushurta. In the modern literature, this condition was first reported by Schwartz (1952). Joshi (1953) was the first person to describe this entity in India.Oral Submucous Fibrosis has been defined as an insidious chronic disease of unknown etiology, reported mainly in Indians, and affecting the entire oral cavity. The basic change is a fibro-elastotic transformation of the connective tissue in the lamina propria preceded by vesicle formation. In its later stages the oral mucous membrane becomes stiff and the patient suffers from trismus and resultant difficulty in eating (Pindborg and Sirsat, 1966).The present paper deals with our experience in the management of Oral Submucous Fibrosis over the past 21/2 years.

Study On Outcome of Different Combination of Dexamethasone, Hyaluronidase and Placental Extract for Treatment of Oral Submucous Fibrosis

KYAMC Journal ◽  
2019 ◽  
Vol 10 (2) ◽  
pp. 77-80
Author(s):  
Md Habibul Hasan ◽  
Md Shahidul Islam ◽  
Manjur E Mahmud ◽  
Ismat Ara Haider ◽  
Fatema Begum
Keyword(s):  
Oral Mucosa ◽  
Buccal Mucosa ◽  
Oral Submucous Fibrosis ◽  
Mouth Opening ◽  
T Test ◽  
Group I ◽  
Wide Range ◽  
Intralesional Injections ◽  
Submucous Fibrosis ◽  
Placental Extract

Background: Oral submucous fibrosis is a chronic debilitating disease of the oral cavity characterized by inflammation and progressive fibrosis of the submucosal tissues. It is a precancerous condition of the oral mucosa characterized by excessive production of collagen leading to inelasticity of the oral mucosa and atrophic changes of the epithelium. A wide range of treatment including drug management, surgical therapy, and physiotherapy have been attempted till date, with varying degrees of benefit, but none have been able to cure this disease. Objectives: To evaluate the efficacy of Intralesional 'Dexamethasone Plus Hyaluronidase plus Placental extract in comparison to intralesional injections of 'Dexamethasone plus Hyaluronidase in the management of OSMF patients. Materials and Methods: Thirty patients with OSMF were randomly divided equally into two groups. Fifteen patients in 'Dexamethasone plus Hyaluronidase(Group-I)' group received biweekly intralesional injections of Dexamethasone (4mg/ml) plus Hyaluronidase 1500 IU in buccal mucosa for a period of 12 weeks. Other Fifteen patients in'Dexamethasone plus Hyaluronidase plus placental extract (Group-II)' group received biweekly intralesional injections of Dexamethasone (4mg/ml) plus Hyaluronidase 1500 IU plus placental extract in buccal mucosa for a period of 12 weeks. Parameters taken in the study were burning sensation, and mouth opening. Descriptive statistics, paired t test and unpaired t test were used for statistical analysis. Results: The pre- and post-treatment Differences were found to be statistically not significant for both the groups (p<0.001) and for both the treatment outcomes. Conclusion: In the present study, the efficacy of Intralesional 'Dexamethasone Plus Hyaluronidase plus Placental extract' showed no superiority over intralesional injections of 'Dexamethasone plus Hyaluronidase' in the management of OSMF patients. KYAMC Journal Vol. 10, No.-2, July 2019, Page 77-80

scholarly journals CLINICAL ASSESSMENT OF OCCURRENCE OF ORAL SUBMUCOUS FIBROSIS IN PATIENTS FROM PATNA DENTAL COLLEGE & HOSPITAL

2019 ◽  
Vol 3 (10) ◽  
Author(s):  
Dr. Tanoj Kumar ◽  
Anurag Rai ◽  
Dr. Minti Kumari ◽  
Dr. Shweta Rai ◽  
Dr. Avanindra Kumar ◽  
...  
Keyword(s):  
Oral Mucosa ◽  
Clinical Assessment ◽  
Histopathological Examination ◽  
Oral Submucous Fibrosis ◽  
Mouth Opening ◽  
Oral Pathology ◽  
Areca Nut ◽  
College Hospital ◽  
Medical College ◽  
Submucous Fibrosis

Oral submucous fibrosis is a chronic progressive scarring disease of oral cavity and oropharynx characterized by epithelial atrophy and juxta epithelial inflammatory reaction with progressive fibrosis of the lamina propria and deeper connective tissue. The resulting stiffness of the oral mucosa then causes a progressive decrease in mouth opening. Hence based on above findings the present study was planned for Clinical Assessment of Occurrence of Oral Submucous Fibrosis in Patients from Patna Medical College & Hospital. The present study was planned in Department of Oral Pathology, Patna Dental College & Hospital, Patna. Total 50 cases of the patient diagnosed with the Oral Sub mucous Fibrosis (OSMF) were evaluated in the present study. History, examination and investigation of patients were done in detail as per predesigned proforma. Histopathological examination of biopsy tissue from oral mucosa was done in patients who had taken pre-therapy and post-therapy (if and when required). X-ray of temporomandibular joint was requested (whenever needed). OSMF is a commonly occurring and widely spread premalignant condition increasingly affecting the youth. The occurrence of OSMF in gutkha chewers is far faster and more severe as compared in other forms of areca nut products chewers. The easy availability and promotions of these areca nut products especially gutkha and pan masala outside the schools colleges and social places has impacted younger population in India which has led to the increased occurrence of OSMF. Keywords: Oral Submucous Fibrosis, OSFM, gutkha, pan masala, etc.

scholarly journals Exemplary Delineation of Osmf Turning Malicious

2017 ◽  
Vol 05 (02) ◽  
pp. 104-109
Author(s):  
Anjali Narwal ◽  
Mala Kamboj ◽  
Shruti Gupta ◽  
Esha Singh ◽  
Pooja Sharma
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cancer ◽  
Oral Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Oral Mucosa ◽  
Oral Submucous Fibrosis ◽  
Potentially Malignant ◽  
Submucous Fibrosis ◽  
Malignant Condition

AbstractOral submucous fibrosis (OSMF) is a well-recognized, potentially malignant condition of the oral cavity that can affect any part of the oral mucosa. It is strongly associated with a risk of oral cancer, although the biology underlying this association is still unresolved. The purpose of this paper is to show the histopathological prototypical illustration of OSMF turning into oral squamous cell carcinoma.

scholarly journals Oral submucous fibrosis: An overview of a challenging entity

2021 ◽  
Vol 0 ◽  
pp. 1-10
Author(s):  
Sonia Gupta ◽  
Manveen Kaur Jawanda
Keyword(s):  
Differential Diagnosis ◽  
Oral Cavity ◽  
Clinical Features ◽  
Oral Mucosa ◽  
Oral Submucous Fibrosis ◽  
Historical Background ◽  
Future Perspectives ◽  
Related Disorder ◽  
Submucous Fibrosis ◽  
Characteristic Features

The oral cavity is considered to be a mirror of the body’s health, as it reflects the manifestations of various systemic disorders. Most of the oral mucosa is derived embryologically from an invagination of ectoderm and thus, like other similar orifices, it may become involved in the disorders that are primarily associated with the skin. Oral submucous fibrosis is one of the commonest precancerous conditions of the oral mucosa involving any part of the oral cavity resulting in tissue scarring, dysphagia and trismus. It is a collagen-related disorder characterized by excessive fibrosis in the oral submucosa, hyalinization and degenerative changes in the muscles. This disease has become a challenging entity for dermatologists due to resemblance of its features to various mucocutaneous conditions. An improper diagnosis can lead to wrong treatment and additional complications. Dermatologists need to be aware of the characteristic features of this disease which can distinguish it from other similar conditions. This review aims to focus on the detailed aspects of oral submucous fibrosis including its historical background, etiological factors, pathogenesis, clinical features, differential diagnosis, investigations, management and future perspectives.

Clinical Evaluation of Buccal Fat Pad and Nasolabial Flap for Oral Submucous Fibrosis Intraoral Defects

2020 ◽  
pp. 194338752096226
Author(s):  
Venkatesh Anehosur ◽  
Pravesh K. Singh ◽  
Punit S. Dikhit ◽  
Hitesh Vadera
Keyword(s):  
Oral Submucous Fibrosis ◽  
Mouth Opening ◽  
Nasolabial Flap ◽  
Fat Pad ◽  
Buccal Fat Pad ◽  
Scar Assessment ◽  
Group I ◽  
Submucous Fibrosis ◽  
The Mean ◽  
Group Ii

Objective: Surgical defects following fibrotomy in oral submucous fibrosis (OSMF) are difficult to manage due to relapse, and local flaps play a pivotal role in covering the defect. The purpose of this study is to compare the buccal fat pad (BFP) and nasolabial flap (NLF) for the reconstruction of intraoral defects after the release of fibrous bands in patients with OSMF. Methods: A prospective study was conducted on patients with OSMF with surgical treatment of fibrotomy excision and reconstruction of the defect with 2 options. Thirty patients with OSMF were divided into 2 groups, group I (BFP) and group II (NLF). Both groups were analyzed for preoperative and postoperative mouth opening and oral commissural width; the extraoral scar was assessed using the Stony Brook Scar Assessment Scale. The data were statistically analyzed using paired and unpaired t test. Results: Thirty patients comprising 27 (90%) male and 3 (10%) female with ages ranging between 19 and 51 years were involved. The mean preoperative and postoperative interincisal mouth opening was 12 mm and 27 mm in group I and 11 mm and 38 mm in group II, respectively, showing a significant increase in group II, and the mean preoperative and postoperative commissural width was 52 mm and 58 mm in group I and 51 mm and 60 mm in group II, respectively. Conclusion: The proposed surgical protocol for the management of OSMF found NLF superior to BFP for the reconstruction of intraoral defects after the release of fibers in patients with OSMF, with a minimal residual scar.

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