scholarly journals The Type of Fat Ingested at Breakfast Influences the Plasma Lipid Profile of Postmenopausal Women

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
J. M. Morillas-Ruiz ◽  
J. M. Delgado-Alarcon ◽  
J. M. Rubio-Perez ◽  
M. D. Albaladejo Oton
Keyword(s):  
At Risk ◽  
Lipid Profile ◽  
Olive Oil ◽  
Total Cholesterol ◽  
Postmenopausal Women ◽  
Plasma Lipid ◽  
Lipid Profiles ◽  
Sample Population ◽  
Plasma Lipid Profile ◽  
Arterial Blood

To assess whether the type of fat ingested at breakfast can modify the plasma lipid profile and other cardiovascular risk variables in postmenopausal women at risk of cardiovascular disease, a longitudinal, randomized, and crossover study was carried out with postmenopausal women at risk of CVD. They were randomly assigned to eat each type of breakfast during one month: 6 study periods (breakfast with the same composition plus butter/margarine/virgin olive oil) separated by two washout periods. On the first and last days of each study period, weight, arterial blood pressure, heart rate, and body mass index were recorded in fasting conditions and a blood sample was collected to measure plasma lipid profile. When comparing final values to baseline values, we only found out statistically significant differences on plasma lipid profiles. Butter-based breakfast increased total cholesterol and HDL, while margarine-based breakfast decreased total cholesterol and LDL and increased HDL. After the olive oil-based breakfast intake, a tendency towards a decrease of total cholesterol and LDL levels and an increase of HDL levels was observed. No statistically significant differences were observed in triglycerides levels, BMI, and arterial pressure in any breakfast type. The margarine-based breakfast was the only one which significantly increased the percentage of volunteers with optimal lipid profiles. The polyunsaturated fat at breakfast has improved the plasma lipid profile in the analyzed sample population, suggesting that PUFA-based breakfast can be advisable in women at risk of CVD.

scholarly journals The lipoprotein/lipid profile is modulated by a gene–diet interaction effect between polymorphisms in the liver X receptor-α and dietary cholesterol intake in French-Canadians

2007 ◽  
Vol 97 (1) ◽  
pp. 11-18 ◽  
Author(s):  
Julie Robitaille ◽  
Alain Houde ◽  
Simone Lemieux ◽  
Daniel Gaudet ◽  
Louis Pérusse ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Total Cholesterol ◽  
Ldl Cholesterol ◽  
Dietary Cholesterol ◽  
Plasma Lipid ◽  
Plasma Lipid Profile ◽  
Plasma Total Cholesterol ◽  
Lipoprotein Lipid ◽  
Liver X Receptor Α ◽  
Cholesterol Intake

Genetic and nutritional factors interact together and modulate the plasma lipid profile. We identified variations in the gene encoding the liver X receptor α (LXRα) and investigated their effects on the plasma lipoprotein/lipid profile. We also examined whether the association between cholesterol intake and plasma lipid profile was modulated by LXRα variants. The LXRα gene was sequenced in thirty-five French-Canadian men with high plasma total cholesterol (>5·0 mmol/l) and LDL-cholesterol (>3·5 mmol/l) concentrations. Dietary cholesterol was obtained from a food-frequency questionnaire. The LXRα c.-115G>A, c.-840C>A and c.-1830T>C genotypes were determined by direct sequencing in 732 subjects. Molecular screening of the LXRα gene revealed sixteen variants. Genotypes c.-115G>A, c.-840C>A and c.-1830T>C (rare allele frequency of 14·3 %, 14·2 % and 11·0 %, respectively) were analysed further. Plasma total cholesterol concentrations were higher in carriers of the -115A, -840A and -1830C allele, compared with the -115G/G, -840C/C and -1830T/T homozygotes (P ≤ 0·05). In a model including the c.-115G>A polymorphism, cholesterol intake, the interaction term c.-115G>A × cholesterol intake (mg/d) and covariates, LXRα-115G>A explained 1·8 % and 2·1 % of the variance in total cholesterol and LDL-cholesterol concentrations (P = 0·02 andP = 0·01), whereas the interaction term explained 2·9 % (P = 0·002) and 2·8 % (P = 0·005), respectively. When subjects were divided into four groups according to the median of cholesterol (290·8 mg) and -115G>A genotypes, high cholesterol intake was associated with higher cholesterol levels in -115A carriers. Similar results were observed for c.-840C>A and c.-1830T>C. These results suggest that cholesterol intake interacts with LXRα variants to modulate the plasma lipid profile.

scholarly journals Assessment of Plasma Lipid Profile among Sudanese Menopausal Women in Khartoum state-Sudan

2019 ◽  
Vol 12 (04) ◽  
pp. 2037-2041
Author(s):  
Alneil Hamza ◽  
Moadah Abbas ◽  
Elyasa Elfaki ◽  
Mariam Ibrahim ◽  
Ezeldine K Abdalhabib ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Postmenopausal Women ◽  
Plasma Lipid ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
P Value ◽  
Time Duration ◽  
Study Results

Postmenopausal women tend to have significant changes in lipid profile when compared with premenopausal women. Incidence of cardiovascular disease after menopause believed to occur due to changes in the plasma lipid levels. This study was conducted to estimate and compare serum levels of total cholesterol(TC), triglycerides(TG), low-density lipoprotein cholesterol (LDL-c) and high-density lipoprotein cholesterol (HDL-c) among Sudanese pre and postmenopausal women. 94 participant women were enrolled in this cross-sectional study. 47 post-menopause women age 48 - 70 years and 47 pre-menopause women age 25-47 years. Estimation of serum lipid profile was carried out using Biosystems colorimetric methods and results statistics were computed by using SPSS. A significant increase in total cholesterol(TC), triglyceride, and LDL-c with a significant decrease in (HDL-c) level among postmenopausal women where found, when compared with pre-menopause women (P-value= <0.05). Total cholesterol and LDL-C level were observed significantly increased according to three interval time duration of menopausal onset (p=0.009 and p=0.034). A positive correlation was observed between the age of and total cholesterol levels in postmenopausal women (R=0.463, P-value =0.001). Study results revealed that postmenopausal status was associated with substantial changes in lipid profile that considered risk factors for cardiovascular disease in Sudanese women.

Effect of an ethanolic extract from Enterolobium cyclocarpum pods on feed intake, egg production, and plasma lipid profile of laying hens

2021 ◽  
Vol 31 ◽  
pp. 1-8
Author(s):  
Ronald Herve Santos Ricalde ◽  
Paloma Lopez Lopez ◽  
Luis Sarmiento Franco ◽  
Carlos Sandoval Castro ◽  
Jose Segura Correa ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Total Cholesterol ◽  
Feed Intake ◽  
Egg Production ◽  
Laying Hens ◽  
Control Diet ◽  
Plasma Lipid ◽  
Ethanolic Extract ◽  
Plasma Lipid Profile ◽  
Enterolobium Cyclocarpum

There is concern about egg cholesterol content. In this study, the effect of an ethanolic extract from Enterolobium cyclocarpum (EEEC) pods in laying hen diets on egg production and plasma lipid profile was investigated. EEEC was added in 0 mg/kg, 60 mg/kg, 120 mg/kg, 240 mg/kg, and 480 mg/kg to the diets. Feed intake was lower in laying hens fed diets with 480 mg/kg of EEEC (p < 0.05). Albumen was less heavy and wide in laying hens fed diets with EEEC, in comparison to those in the control diet (p < 0.05). No significant effect of EEEC on cholesterol in plasma was observed (p < 0.08); however, a significant increase of high-density lipids (HDL) in proportion of total cholesterol was observed in hens supplemented with 120 mg/kg of EEEC (p < 0.05). In conclusion, EEEC reduced albumen weight and wide in eggs, and 120 mg/kg of EEEC in the diet increased HDL in proportion to total cholesterol in blood.

scholarly journals A Systematic Review: Predict the COVID-19 Severity by HDL and Triglycerides Level

2021 ◽  
Vol 5 (4) ◽  
pp. 01-04
Author(s):  
Daniel Setiawan Nathan ◽  
Hoo Yumilia
Keyword(s):  
Systematic Review ◽  
Lipid Profile ◽  
Plasma Lipid ◽  
Lipid Profiles ◽  
Clinical Severity ◽  
Atherogenic Dyslipidemia ◽  
Strongly Correlated ◽  
Plasma Lipid Profile ◽  
Review Reports ◽  
Research Studies

Lipids are a major component in the process of SARS-CoV-2 infection. The clinical significance of plasma lipid profiles during COVID-19 has been described in several studies to date. The purpose of this mini-review is to summarize previous research studies regarding the association of plasma lipid profile with the clinical severity of SARS-CoV-2 infection. This edition presents mini-review reports on research studies related to LDL and TG levels that can predict severity in patients with COVID-19. Atherogenic dyslipidemia that occurs during infection is reported to be very strongly correlated with a more severe prognosis in COVID-19 infection. Therefore, lipid profiles should be performed to indicate acute and measurable inflammation in COVID-19 patients, and fish oil and statin therapy should also be considered to improve the condition.

scholarly journals Dietary intake of energy and selected nutrients and plasma lipid profile in young women and men with different levels of physical activity

2013 ◽  
Vol 5 (1) ◽  
pp. 99-107
Author(s):  
Marzena Malara ◽  
Elżbieta Hübner-Woźniak
Keyword(s):  
Physical Activity ◽  
Dietary Intake ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Young Women ◽  
Venous Blood ◽  
Plasma Lipid ◽  
Blood Collection ◽  
Plasma Lipid Profile ◽  
Different Levels

Summary Study aim: The purpose was to assess dietary intake of energy and selected nutrients and plasma lipid profile in young women and men with different levels of physical activity. Material and methods: The research included a total of 116 female and male students at the University of Physical Education who differed in their levels of physical activity. Analysis of the diets was based on 24-hour dietary interviews collected over 4 days prior to blood collection. Concentrations of total cholesterol (TC), HDL cholesterol (HDL-C), and triacylglycerol (TG) were measured in venous blood. In addition, the concentration of LDL cholesterol (LDL-C) and the ratios of TC / HDL-C and LDL-C/HDL-C were calculated. Results: Women, regardless of their physical activity levels, were characterized by a significantly higher concentration of total cholesterol in plasma (4.8 and 4.5 mmol/L, respectively - in training participants; 4.7 and 4.3 mmol/L, respectively - in non-training participants), although their dietary intake of cholesterol was significantly lower in comparison with the corresponding groups of men (282.0 and 484.7 mg, respectively - in training participants; 252.6 and 400.2 mg, respectively - in non-training participants). A trend toward a worse lipid profile of training women and men compared with the corresponding groups of non-training participants was also observed. Conclusions: Increased physical activity in the groups of training women and men was not a sufficient stimulus to induce positive changes in their lipid profiles. Nor can it be excluded that the observed differences were the result of diet, as dietary intake of cholesterol in the groups of training women and men was higher compared with the corresponding groups of non-training participants.

scholarly journals Lipid Profile and Prevalence of Dyslipidemia in Pre- and Postmenopausal Women in Yaounde, Cameroon

2019 ◽  
pp. 1-11
Author(s):  
Nkeunen Gerard ◽  
Tsafack Takadong Julie Judith ◽  
Simo Gustave ◽  
Betrand Ayuk Tambe ◽  
Ayangma Celestin Roger ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Total Cholesterol ◽  
Postmenopausal Women ◽  
Energy Homeostasis ◽  
Plasma Lipid ◽  
Military Hospital ◽  
Cross Sectional ◽  
Mean Values ◽  
Significant Difference ◽  
The Mean

Aims: Lipids serve several important physiologic functions like energy homeostasis or biosynthesis of hormone within the human body. The deterioration of lipid metabolism which is favoured by menopause is the source of cardiovascular diseases. This study aimed to determine the plasma lipid profile and dyslipidemia prevalence of some Cameroonian women. Study Design: This was a cross-sectional study. Place and Duration of Study: The enrollment took place at the Yaounde Military Hospital from November 2016 to July 2017. Methodology: To achieve this goal, two sets of 105 postmenopausal and 127 premenopausal participants were enrolled in this study. 5ml of blood were collected on EDTA coated tubes from each participant. Enzymatic methods were used to evaluate total cholesterol, HDL cholesterol and triglyceride, while LDL cholesterol was determined using the Friedewald equation. These biological parameters were used to determine dyslipidemia. Thereafter, they were compared within age and year since menopause subgroups. Results: There was no significant difference in the mean values of total cholesterol, HDL-C, LDL-C as well as triglyceride between premenopausal and postmenopausal women. The mean HDL-C concentration was stable in the age subgroups while the mean total cholesterol and LDL-C were slightly increasing as postmenopausal participants got older. LDL-C level was significantly higher in women who had been in menopause for more than 15 years. The overall dyslipidemia prevalence was 53%. Dyslipidemia was significantly higher in the subgroup of women who had freshly entered menopause. Conclusion: Even though there was no change in the mean concentration of the plasma lipid parameters, of pre- and postmenopausal participants there was a general need to improve their lifestyle in order to reduce dyslipidemia prevalence.

scholarly journals Metabolic effects of dehydroepiandrosterone replacement therapy in postmenopausal women

2001 ◽  
pp. 457-461 ◽  
Author(s):  
A Lasco ◽  
N Frisina ◽  
N Morabito ◽  
A Gaudio ◽  
E Morini ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
Glucose Tolerance ◽  
Lipid Profile ◽  
Postmenopausal Women ◽  
Plasma Lipid ◽  
Density Lipoprotein ◽  
Term Treatment ◽  
Plasma Lipid Profile ◽  
Long Term Treatment

OBJECTIVE: To investigate whether long-term treatment with dehydroepiandrosterone (DHEA) in postmenopausal women can modify insulin sensitivity and plasma lipid profile. DESIGN AND METHODS: Twenty healthy postmenopausal women with serum dehydroepiandrosterone sulfate (DHEA-S) concentrations <2.5 micromol/l were enrolled and randomly assigned to two different treatment groups: group 1 were treated with micronized DHEA, 25 mg/day at 0800 h for 12 months; group 2 were treated with an identical placebo tablet. At the beginning and at the end of the study, plasma lipid profile, glucose tolerance (oral glucose tolerance test) and insulin sensitivity (euglycemic hyperinsulinemic clamp: M index) were assessed. RESULTS: After 12 months, the group treated with DHEA showed a considerable improvement of insulin sensitivity (M index +29.55%, P=0.01) and lipid pattern (high-density lipoprotein cholesterol +11.61%, P=0.03; low-density lipoprotein cholesterol -11.07%, P=0.04; triglycerides -19.60%, P=0.03), but glucose tolerance did not change. No modifications were observed in the placebo group. CONCLUSIONS: Long-term treatment with DHEA ameliorates some metabolic parameters that are linked to increased cardiovascular risk and, consequently, this seems to be an interesting therapeutic tool in the management of the postmenopausal syndrome.

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