scholarly journals Synthesis of Carbon Nanotube Incorporated Molecular Imprinted Polymer with Binding Affinity towards Testosterone

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Anju Augustine ◽  
Beena Mathew

A novel polymer was synthesised using functionalized carbon nanotube and acrylamide as the polymer support for the separation of testosterone. The developed polymers were characterised using FT-IR, XRD, and SEM techniques. Imprinted polymer showed specificity towards the template testosterone. Among the various polymers, the MWCNT incorporated polymer showed high binding towards the used template. Investigation of the selectivity characteristics revealed that the developed polymer showed selectivity toward the template testosterone than similar compounds. The bound template could be totally recovered and regenerated polymer maintains its recognition property after repeated use. On the basis of the results, the imprinted polymer can be applied for the direct extraction of testosterone in clinical analysis.

2013 ◽  
Vol 53 ◽  
pp. 64-70 ◽  
Author(s):  
N. Farhanah. Ab. Halim ◽  
M. Noor. Ahmad ◽  
A.Y. Md. Shakaff ◽  
N. Deraman

2020 ◽  
Vol 42 (6) ◽  
pp. 856-856
Author(s):  
Sehrish Qazi Sehrish Qazi ◽  
Huma Shaikh Huma Shaikh ◽  
Ayaz Ali Memon Ayaz Ali Memon ◽  
and Shahabuddin Memon and Shahabuddin Memon

Among all psychotropic alkaloids, nicotine is more addictive, carcinogenic and capable of causing many health problems. This work is based on the development of highly robust, cheap, reliable, selective and sensitive nicotine imprinted graphene oxide nanocomposite (ImpGO nanocomposite) based optical sensor for determination of nicotine in human plasma. The ImpGO nanocomposite has been thoroughly characterized using different techniques i.e. FT-IR, SEM, TEM, Raman, etc. These characterizations revealed that ImpGO nanocomposite is comprised of single layer of graphene oxide successfully modified with imprinted polymer. The synthesized material was utilized to selectively determine nicotine using UV-vis spectrophotometer in BR buffer of 0.1 M at pH 3 and diluted human plasma. The effect of parameters such as buffer concentration, pH, amount of nanocomposite, etc on determination of nicotine using ImpGO nanocomposite were studied thoroughly. Thus, a sensitive optical method was developed for determination of nicotine in human plasma with linear range of 22-370 pM along with LOD and LOQ of 7 pM and 22 pM, respectively. The selectivity of sensor was evaluated using homologues of nicotine such as nicotine amide, caffeine and cotinine. The results obtained from biological samples showed that developed optical sensor is efficient in complex matrices of real sample.


2015 ◽  
Vol 203 ◽  
pp. 32-40 ◽  
Author(s):  
M. Sánchez-Polo ◽  
I. Velo-Gala ◽  
Jesús J. López-Peñalver ◽  
J. Rivera-Utrilla

Fuel ◽  
2017 ◽  
Vol 210 ◽  
pp. 380-389 ◽  
Author(s):  
Liz Nayibe Martínez Saavedra ◽  
Bruno Eduardo Lobo Baeta ◽  
Márcio César Pereira ◽  
Luiz Carlos Alves de Oliveira ◽  
Adilson Candido da Silva

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