scholarly journals First Reported Case of Proliferative Retinopathy in Hemoglobin SE Disease

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Paul Baciu ◽  
Christopher Yang ◽  
Aldo Fantin ◽  
Deborah Darnley-Fisch ◽  
Uday Desai
Keyword(s):  
African American ◽  
Sickle Cell ◽  
Laser Photocoagulation ◽  
Proliferative Retinopathy ◽  
Routine Examination ◽  
Ocular Complications ◽  
First Case ◽  
The Future ◽  
Sea Fan

We report the first case of proliferative sickle cell retinopathy in a patient with hemoglobin SE (Hb SE) disease. Only a few dozen cases of Hb SE disease have been reported previously, and none had evidence of proliferative retinopathy. A 56-year-old African American man presented to our clinic for routine examination and was found to have sea-fan peripheral neovascularization bilaterally without maculopathy. Hemoglobin analysis revealed Hb SE heterozygosity. Sector laser photocoagulation to areas of nonperfusion in both eyes resulted in regression of the peripheral neovascularization over a period of 6 months. Although Hb SE disease is rare, the incidence of Hb SE disease is postulated to rise in the future. Awareness of its potential ocular complications is needed to appropriately refer these patients for screening.

scholarly journals Peripheral Retinal Neovascularization with Vitreous Hemorrhage in HIV Retinopathy

2017 ◽  
Vol 8 (2) ◽  
pp. 353-357 ◽  
Author(s):  
Kim Jiramongkolchai ◽  
Tin Yan Alvin Liu ◽  
J. Fernando Arevalo
Keyword(s):  
African American ◽  
Laser Photocoagulation ◽  
African American Woman ◽  
American Woman ◽  
Vitreous Hemorrhage ◽  
Retinal Ischemia ◽  
Retinal Neovascularization ◽  
Clinical Spectrum

We report a case of peripheral retinal neovascularization and vitreous hemorrhage in the setting of HIV retinopathy that can serve to extend the clinical spectrum of this condition. A 53-year-old African-American woman with AIDS was referred for decreased vision in the left eye and was found to have peripheral retinal neovascularization and vitreous hemorrhage. She had a workup that was negative for etiologies of retinal ischemia. Peripheral laser photocoagulation was used to treat areas of nonperfusion. To our knowledge, this is the first reported case of peripheral retinal neovascularization and vitreous hemorrhage in the setting of HIV retinopathy, and it can serve to extend the clinical spectrum of this condition.

scholarly journals Shift in racial communities impacted by COVID-19 in California

2020 ◽  
pp. jech-2020-215148
Author(s):  
Raphael E Cuomo
Keyword(s):  
African American ◽  
Asian American ◽  
Linear Trend ◽  
Correlation Coefficients ◽  
Longitudinal Distribution ◽  
County Level ◽  
White American ◽  
First Case ◽  
Exponential Trend ◽  
African American Communities

IntroductionSince the first case of COVID-19 was recorded in California, the geospatial distribution of disease cases has fluctuated over time. Given documented racial disparities in other parts of the country, longitudinal convergence of COVID-19 rates around race groups warrants assessment.MethodsCounty-level cases for COVID-19 were collected from the Johns Hopkins University, and racial distributions were collected from the American Community Survey. Pearson’s correlation coefficients were computed for each day since COVID-19 was first reported in California, and the longitudinal distribution of each race-specific set of correlation coefficients was assessed for stationarity, linear trend and exponential trend.ResultsEarlier in the outbreak, the distribution of COVID-19 was most highly correlated with Asian American communities; after approximately 100 days, the distribution of COVID-19 most closely resembled that of African American communities. For every day in this dataset, the county-level distribution of COVID-19 was negatively correlated with the distribution of White American communities in California.DiscussionThe geospatial distribution of COVID-19 in California has increasingly resembled that of African American communities within the state. Further study should be conducted to characterise potentially disproportionate impacts of the COVID-19 pandemic across race groups.

scholarly journals Laser photocoagulation for proliferative retinopathy in sickle haemoglobin C disease

Eye ◽  
1993 ◽  
Vol 7 (5) ◽  
pp. 703-706 ◽  
Author(s):  
Peter D Fox ◽  
Kyra Minninger ◽  
Mark L Forshaw ◽  
S J Rupert Vessey ◽  
Joanne S Morris ◽  
...  
Keyword(s):  
Laser Photocoagulation ◽  
Proliferative Retinopathy ◽  
Haemoglobin C

scholarly journals Myelopathy in sickle cell disease: a case-oriented review

2021 ◽  
Author(s):  
Igor Vilela Brum ◽  
Guilherme Diogo Silva ◽  
Diego Sant'Ana Sodre ◽  
Felipe Melo Nogueira ◽  
Samira Luisa dos Apostolos Pereira ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Case Report ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Case Reports ◽  
Spinal Cord Infarction ◽  
Sensory Level ◽  
Cell Disease ◽  
Hematopoietic Tissue ◽  
First Case

Background: Although neurological complications are well recognized in sickle cell disease (SCD), myelopathy has been rarely described. We present the first case report of longitudinally extensive myelitis (LETM) in SCD and review the differential diagnosis of myelopathy in these patients. Design and setting: case-oriented review. Methods: We report the case of a 29-year-old African-Brazilian man with SCD, who experienced a subacute flaccid paraparesis, with T2 sensory level and urinary retention. CSF analysis showed a lymphocytic pleocytosis and increased protein levels. MRI disclosed a longitudinally extensive spinal cord lesion, with a high T2/STIR signal extending from C2 to T12. Serum anti-aquaporin-4 antibody was negative. We searched Medline/ PubMed, Embase, Scopus, and Google Scholar databases for myelopathy in SCD patients. Results: Spinal cord compression by vertebral fractures, extramedullary hematopoietic tissue, and Salmonella epidural abscess have been reported in SCD. We found only three case reports of spinal cord infarction, which is unexpectedly infrequent compared to the prevalence of cerebral infarction in SCD. We found only one case report of varicella-zoster myelitis and no previous report of LETM in SCD patients. Conclusion: Specific and time-sensitive causes of myelopathy should be considered in SCD patients. In addition to compression and ischemia, LETM should be considered as a possible mechanism of spinal cord involvement in SCD.

“A Ghost of the Future”: Racial (Mis)perception and Black Subjectivity in LeRoi Jones’s Dutchman

2015 ◽  
Author(s):  
Carol Bunch Davis
Keyword(s):  
African American ◽  
Racial Uplift ◽  
Freedom Struggle ◽  
Black Subjectivity ◽  
The Future ◽  
White Femininity ◽  
The Right

This chapter offers a reading of Amiri Baraka's 1964 play, Dutchman, focusing on its use of race icons to engage with white liberal response to racial uplift ideology and its implications for black subjectivity. The chapter considers Rashid Johnson's restaging of Dutchman and his assertion that his project creates an opportunity to find identity somewhere between “the narrative of struggle and the narrative of Negro Exceptionalism,” noting that it resonates in Baraka's (aka LeRoi Jones) contention that the struggle is as much about “the right to choose.” The chapter challenges claims that Dutchman relies upon essentialized blackness and the degradation of white femininity in order to prop up the identity of the African American protagonist, Clay. Instead, it argues that the play unpacks whiteness's investment in uplift ideology by employing a variety of cultural genealogies and practices to sketch identity, thus exposing the vulnerabilities of the African American Freedom Struggle era iterations of uplift ideology.

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