scholarly journals Antimicrobial Applications of Transition Metal Complexes of Benzothiazole Based Terpolymer: Synthesis, Characterization, and Effect on Bacterial and Fungal Strains

2014 ◽  
Vol 2014 ◽  
pp. 1-16 ◽  
Author(s):  
Mohamed A. Riswan Ahamed ◽  
Raja S. Azarudeen ◽  
N. Mujafar Kani
Keyword(s):  
Metal Complexes ◽  
Elemental Analysis ◽  
Biological Activities ◽  
Gel Permeation Chromatography ◽  
Spectral Studies ◽  
X Ray Diffraction ◽  
Spectral Techniques ◽  
H Nmr ◽  
Uv Visible ◽  
C Nmr

Terpolymer of 2-amino-6-nitro-benzothiazole-ethylenediamine-formaldehyde (BEF) has been synthesized and characterized by elemental analysis and various spectral techniques like FTIR, UV-Visible, and1H and13C-NMR. The terpolymer metal complexes were prepared with Cu2+, Ni2+, and Zn2+metal ions using BEF terpolymer as a ligand. The complexes have been characterized by elemental analysis and IR, UV-Visible, ESR,1H-NMR, and13C-NMR spectral studies. Gel permeation chromatography was used to determine the molecular weight of the ligand. The surface features and crystalline behavior of the ligand and its complexes were analyzed by scanning electron microscope and X-ray diffraction methods. Thermogravimetric analysis was used to analyze the thermal stability of the ligand and its metal complexes. Kinetic parameters such as activation energy(Ea)and order of reaction (n) and thermodynamic parameters, namely,ΔS,ΔF,S*, andZ, were calculated using Freeman-Carroll (FC), Sharp-Wentworth (SW), and Phadnis-Deshpande (PD) methods. Thermal degradation model of the terpolymer and its metal complexes was also proposed using PD method. Biological activities of the ligand and its complexes were tested againstShigella sonnei,Escherichia coli,Klebsiellaspecies,Staphylococcus aureus,Bacillus subtilis, andSalmonella typhimuriumbacteria andAspergillus flavus,Aspergillus niger,Penicilliumspecies,Candida albicans,Cryptococcus neoformans,Mucor speciesfungi.

scholarly journals Synthesis, Spectroscopic, and Magnetic Studies of Mono- and Polynuclear Schiff Base Metal Complexes Containing Salicylidene-Cefotaxime Ligand

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
J. R. Anacona ◽  
Johan Calvo ◽  
Ovidio A. Almanza
Keyword(s):  
Schiff Base ◽  
Metal Complexes ◽  
Schiff Base Ligand ◽  
Magnetic Moments ◽  
Spectral Studies ◽  
Magnetic Studies ◽  
H Nmr ◽  
Uv Visible ◽  
Schiff Base Metal Complexes ◽  
C Nmr

Metal complexes of a Schiff base ligand derived from cefotaxime and salicylaldehyde were prepared. The salicilydene-cefotaxime ligand (H2L) and mononuclear [M(L)] (M(II) = Co, Ni and Cu), dinuclear [Ag2(L)(OAc)2], and tetranuclear metal complexes [M4(L)(OH)6] (M(II) = Ni, Cu) were characterized on the basis of analytical, thermal, magnetic, and spectral studies (IR, UV-visible, 1H NMR, 13C NMR, and EPR). The electronic spectra of the complexes and their magnetic moments suggesttetrahedral geometry for the isolated complexes. The complexes are nonelectrolytes and insoluble in water and common organic solvents but soluble in DMSO.

Synthesis and Pharmacological Activities of Some New 2-[1-Heptyl-3-(4- methoxybenzyl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]acetohydrazide Derivatives

2014 ◽  
Vol 69 (9-10) ◽  
pp. 969-981 ◽  
Author(s):  
Olcay Bekircan ◽  
Emre Mentese ◽  
Serdar Ulker
Keyword(s):  
Nmr Spectroscopy ◽  
Elemental Analysis ◽  
Lipase Activity ◽  
Spectral Studies ◽  
Antituberculosis Activity ◽  
Pharmacological Activities ◽  
Mass Spectral ◽  
H Nmr ◽  
Acetohydrazide Derivative ◽  
C Nmr

Abstract In the present investigation, the key intermediate acetohydrazide derivative 5 was synthesized starting from 3-(4-methoxybenzyl)-4-amino-4,5-dihydro-1,2,4-triazol-5-one (1) by a four-step reaction. Thiosemicarbazides 6a-f and arylidenehydrazide derivatives 8a-d were obtained from compound 5. The cyclization of compounds 6a-f in the presence of NaOH resulted in the formation of compounds 7a-f. The compounds were characterized by IR, 1H NMR, 13C NMR spectroscopy, elemental analysis and mass spectral studies. The compounds were tested for their anti-lipase, anti-α-glucosidase and anti-mycobacterial activities. Compounds 6b and 8c exhibited excellent anti-lipase activity, and compound 8d showed excellent anti-a-glucosidase activity. Compounds 3 and 4 exhibited good antituberculosis activity

Synthesis and Biological Activities of Some Schiff's Bases from 4-amino-3-(3-hydroxybutyl)-1H-1, 2, 4-triazole-5-thione

2009 ◽  
Vol 2009 (4) ◽  
pp. 208-211 ◽  
Author(s):  
Jing Zhang ◽  
Lixue Zhang ◽  
Xinxiang Lei ◽  
Changfeng Zhou ◽  
Xiaodan Fu ◽  
...  
Keyword(s):  
Plant Growth ◽  
Elemental Analysis ◽  
Mass Concentration ◽  
Biological Activities ◽  
Schiff’S Bases ◽  
H Nmr ◽  
Schiff's Bases ◽  
High Yields ◽  
C Nmr ◽  
Growth Regulating Activity

Sixteen novel Schiff's bases have been synthesised in high yields from 4-amino-3-(3-hydroxybutyl)-1 H-1, 2, 4-triazole-5-thione. All the newly synthesised compounds have been characterised by elemental analysis, IR, 1H NMR, 13C NMR and MS. Plant growth-regulating activity tests showed that most compounds have remarkable effects on the growth of wheat and radish at a mass concentration of 50μg mL−1.

scholarly journals Synthesis, Characterization and Antimicrobial Activity of Methylquinolino[3,2-b][1,5]benzodiazepine and Methylquinolino[3,2-b][1,5]benzoxazepine and its Various Metal Complexes

2007 ◽  
Vol 4 (1) ◽  
pp. 32-38 ◽  
Author(s):  
B. Basavaraju ◽  
H. S. Bhojya Naik ◽  
M. C. Prabhakara
Keyword(s):  
Antimicrobial Activity ◽  
Metal Complexes ◽  
Antimicrobial Agents ◽  
Spectral Studies ◽  
Antibacterial And Antifungal Activity ◽  
H Nmr ◽  
Uv Visible ◽  
Bacteria And Fungi ◽  
Antibacterial And Antifungal ◽  
Metal Ligand

2-Chloro-6-methylquinoline-3-carbaldehyde was condensed witho-Phenylenediammine and 2-aminophenol in presence of potassium iodide. The resulting Methylquinolino[3,2-b][1,5]benzodiazepine (MQBD) and Methylquinolino[3,2-b][1,5]benzoxazepine(MQBO) were characterized by elemental analysis and spectral studies. The metal chelatesvizPd(II), Rh(III) and Ru(III) of ligands were prepared and characterized by metal-ligand (M:L) ratio, UV-Visible, IR,1H NMR spectroscopes and magnetic properties. The antibacterial and antifungal activity of MQBD, MQBO and its metal complexes were screened against various bacteria and fungi. The results show that all these samples are good antimicrobial agents.

Synthesis and antimicrobial properties of N-substituted derivatives of (E)-2′,3″-thiazachalcones

2015 ◽  
Vol 70 (1-2) ◽  
pp. 45-50
Author(s):  
Asu Usta ◽  
Hacer Taşkıran
Keyword(s):  
Elemental Analysis ◽  
Antimicrobial Properties ◽  
Antibacterial Activities ◽  
Spectral Studies ◽  
Gram Negative Bacteria ◽  
Gram Negative ◽  
Mass Spectral ◽  
H Nmr ◽  
Derivatives Of ◽  
C Nmr

Abstract N-alkyl substituted 2′,3″-thiazachalcones {3-[(1E)-3-(4-methylthiophene-2-yl)-3-oxoprop-1-en-1-yl]-1-alkyl (C5–12,14) pyridinium bromides} were synthesized by a two-step reaction. The newly synthesized compounds were characterized by IR, 1H NMR, 13C NMR, elemental analysis and mass spectral studies. The synthesized compounds were tested for antibacterial activities and found to be more active against Gram-positive as compared to Gram-negative bacteria.

Simple and efficient approach to synthesis of [1,2,4]triazolo[4,3-b][1,2,4,6]thiatriazine- 1-oxides from N-triazol-3-ylamidines

2017 ◽  
Vol 23 (2) ◽  
pp. 97-100 ◽  
Author(s):  
Azhar Hajri ◽  
Mohamed Lamjed Marzouki
Keyword(s):  
Elemental Analysis ◽  
Thionyl Chloride ◽  
Spectral Studies ◽  
Efficient Approach ◽  
H Nmr ◽  
C Nmr

AbstractA facile method for the synthesis of [1,2,4]triazolo[4,3-b][1,2,4,6]thiatriazine 1-oxides 3a–h is presented. The approach involves a reaction between N-triazol-3-ylamidines 2a–h and thionyl chloride in the presence of pyridine. The structures of the synthesized compounds were confirmed by spectral studies including IR, 1H NMR, 13C NMR, MS and elemental analysis.

Synthesis, characterization, thermal properties of silicon(iv) compounds containing guanidinato ligands and their potential as CVD precursors

RSC Advances ◽  
2015 ◽  
Vol 5 (88) ◽  
pp. 71637-71643 ◽  
Author(s):  
Liyong Du ◽  
Wenxiang Chu ◽  
Hongyan Miao ◽  
Chongying Xu ◽  
Yuqiang Ding
Keyword(s):  
Thermal Properties ◽  
Elemental Analysis ◽  
X Ray Diffraction ◽  
X Ray ◽  
H Nmr ◽  
C Nmr

The title compounds of the type (Me3Si)2N–C(N′R)(–N′′RSiMe3) (with R = iPr or Cy) as potential CVD precursors have been synthesized and characterized by X-ray diffraction, 1H NMR, 13C NMR, 29Si NMR and elemental analysis where necessary.

scholarly journals Synthesis, Characterization and Printing Application of Solvent Dyes Based on 2-Hydroxy-4-n-octyloxybenzophenone

2011 ◽  
Vol 8 (2) ◽  
pp. 615-620 ◽  
Author(s):  
Bharat C. Dixit ◽  
Hitendra M. Patel
Keyword(s):  
Spectral Data ◽  
Elemental Analysis ◽  
Cotton Fiber ◽  
Aromatic Amines ◽  
Spectral Studies ◽  
Structure Property ◽  
H Nmr ◽  
Property Relationship ◽  
Structure Property Relationship ◽  
Uv Visible

Solvent dyes have been prepared by the coupling of diazo solution of different aromatic amines with 2-hydroxy-4-n-octyloxybenzophenone. The resultant dyes were characterized by elemental analysis as well as IR and1H NMR spectral studies. The UV-Visible spectral data have also been discussed in terms of structure property relationship. The printing of all the dyes on cotton fiber was monitored. The result shows that better hue was obtained on printing on cotton fiber and it is resulted in yellow to reddish brown colorations which showed a good fastness to light, with poor to good fastness to washing, perspiration and sublimation, however it shows poor rubbing fastness.

scholarly journals 3D-Metal Complexes Derived from Proton Pump Inhibitors-Synthesis, Characterization and Biological Studies

2012 ◽  
Vol 9 (4) ◽  
pp. 1919-1928 ◽  
Author(s):  
Suman Malik ◽  
Supriya Das ◽  
Archana Singh ◽  
Liviu Mitu
Keyword(s):  
Antimicrobial Activity ◽  
Magnetic Susceptibility ◽  
Transition Metal Ions ◽  
Spectral Studies ◽  
X Ray Diffraction ◽  
H Nmr ◽  
Pyridine Nitrogen ◽  
Biological Studies ◽  
3D Metal Complexes ◽  
Uv Visible

Complexes of lansoprazole 2[[[[3-methyl, 4-(2′,2′,2′-trifluoro-ethoxy)]-2-pyridinyl] methyl]sulfonyl]–1H–benzimidazole (LAN) with chlorides of Co(II), Ni(II), Cu(II), Mn(II) and Zn(II) were synthesized. LAN is a weak base and it can form several complexes with transition and non-transition metal ions. It should be noticed that the reaction of all the metal salts yielded bis(ligand) complexes of the general formula [ML2(H2O)2] and [ML2] (M = Co, Ni, Cu, Mn and Zn). The complexes were characterized by elemental analysis, molar conductivity, magnetic susceptibility measurements, IR,1H-NMR, UV-visible spectral studies, ESR, SEM, x-ray diffraction, TGA and mass spectra. In all the complexes ligand is coordinated by participation of the pyridine nitrogen of the benzimidazole ring and sulphonyl group. Electronic spectra and magnetic susceptibility reveal octahedral geometry for Mn(II), Co(II), Ni(II) and Cu(II) complexes and tetrahedral for Zn(II) complex. The antimicrobial activity of the ligand and its complexes against bacteriaPseudomonas aeruginosa, Staphylococcus aureusand fungiAspergillus nigerandAspergillus flavouswere investigated. The effect of metals on the antimicrobial activity of the ligand has been discussed.

scholarly journals Synthesis, Characterization, and Dielectric Behaviors of 4-Diethanolaminomethyl Styrene and Benzyl Methacrylate Copolymer and Its Metal Complexes

2019 ◽  
Vol 2019 ◽  
pp. 1-12
Author(s):  
Aslisah Acikses ◽  
Fethiye Öksüz
Keyword(s):  
Metal Ions ◽  
Metal Complexes ◽  
Elemental Analysis ◽  
Magnetic Measurements ◽  
Gel Permeation Chromatography ◽  
Xrd Analysis ◽  
Molecular Formula ◽  
Tetrahedral Geometry ◽  
H Nmr ◽  
Ft Ir

In this paper, the copolymer of 4-diethanolaminomethyl styrene (DEAMSt) with benzyl methacrylate (BMA) was synthesized and characterized using various spectral techniques such as FT-IR, 1H-NMR, elemental analysis, SEM, XRD, TGA, DTA, and DSC. The copolymer-metal complexes were prepared with Co(II), Ni(II), and Zn(II) metal ions, and poly(DEAMSt-co-BMA) was used as ligand. The copolymer-metal complexes were characterized using elemental analysis. FT-IR, SEM, XRD, magnetic measurements, and the thermal behaviors of the copolymer-metal complexes were studied using TGA, DTA, and DSC. The compositions of DEAMSt and BMA in the copolymer by 1H-NMR spectra were determined as 0.49 and 0.51, respectively. Both poly(DEAMSt-co-BMA) and poly(DEAMSt-co-BMA)-Zn complexes were heated up to various temperatures. As the temperature increased, the intensities of O-H stretching bands at 3125–3429 cm−1 resulting from hydrogen bond decreased and shifted to high frequency. Gel permeation chromatography was used to determine the average molecular weights and polydispersity index of the poly(DEAMSt0.49-co-BMA) ligand. Both the molecular formula and C, H, and N % were estimated using elemental analysis, and the amounts of metal by mole (%) in the complexes were estimated by SEM-EDX measurements. The XRD patterns of ligand and metal complexes showed that they were of an amorphous nature. The synthesized metal complexes were annealed at 100°C for 1 h in order to obtain crystalline metal complexes. After annealing at 100°C, the metal complexes showed the crystalline structure. The SEM and XRD analysis of the metal complexes confirmed that metal ions contributed to the structure of the ligand. According to the magnetic measurements, it was suggested that geometrical structure for all complexes was tetrahedral geometry and the ratio of ligand to metal was found to be 2 : 1. The dielectric measurements of the ligand and its metal complexes were investigated depend on frequency.

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