scholarly journals Oligodendroglioma Arising in Mature Cystic Teratoma

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Betül Ünal ◽  
Faruk Güleç ◽  
Murat Şedele

Background.Development of neuroepithelial tumors from mature cystic teratoma is very rare. We present a case of oligodendroglioma developing inside mature cystic teratoma.Case.Eighteen-years-old female, right adnexal mass with solid and cystic areas was detected. Sections showed all three germ layers. Also, a tumoral lesion was observed in a glial fibrillary matrix. Tumor was composed of monotonous, uniform cells which have oval-round nucleus, perinuclear halo, and indistinct cytoplasm. GFAP, EGFR, P53 were positive.Conclusions.We diagnosed oligodendroglioma arising from mature cystic teratoma. There was no recurrence at the end of 13 months followup. The number of cases which have been reported in the literature is only a few.

2018 ◽  
Vol 12 (2) ◽  
pp. 48-51
Author(s):  
Monica Gurung ◽  
Gehanath Baral

Aims: To find out the prevalence of adnexal mass during Cesarean Section, its management and histological profile.Methods: This is a retrospective study conducted for 4 years from 2013 to 2017 at Paropakar Maternity and Women’s Hospital, Kathmandu, Nepal. There were 18993 Cesarean Sections out of 72263 total births screened for adnexal masses from operation theatre register and record section.Results: The incidence of adnexal mass during cesarean section was 0.31% (58 out of 18993). Among them 15.52 % diagnosed antenatally and 84.48 % were incidentally diagnosed during cesarean section. Among 58 cases, 6 (10%) were bilateral amounting to 64 adnexal masses among which 35 (54.69%) masses had cystectomy, 20 (31.25%) masses had oophorectomy, 6 (9.37%) had aspiration/ drilling done and 3(4.69 %) masses were left without intervention. Among those cases only 48 histopathological reports were available. All the masses were benign and the most common was benign mature cystic teratoma (34; 69.38 %) and the least common was fibroma (1; 2.04%).Conclusions:  Adnexal masses during cesarean section should undergo surgical removal.


2019 ◽  
Vol 17 (01) ◽  
pp. 128-130
Author(s):  
Karishma Malla Vaidya ◽  
Bigya Shrestha

Lymphangiomas are slow-growing tumors that remain asymptomatic for a long time, with the tumor being identified incidentally during histopathological examination after excision. Mature cystic teratoma is benign tumor consisting of mature tissue derived from two or three germ layers. We have 47-year-old woman who underwent total abdominal hysterectomy for right adnexal mass. As her ultrasound report revealed a right adnexal mass with solid and cystic components. The histological analysis along with immunohistochemistry (D2-40) maker confirmed the diagnosis of lymphangioma of the ovary coexisting with mature cystic teratoma. There is paucity of reported case of co-existing these two tumors in same tissue.Keywords: D2-40; lymphangioma; mature cystic teratoma; ovary.


2019 ◽  
Vol 3 (1) ◽  
pp. 54-56
Author(s):  
Shankar Bastakoti ◽  
Nirmal Lamichhane ◽  
Sadina Shrestha ◽  
Ishan Dhungana

Adrenal leiomyoma is a rare neoplasm and usually associated with adrenal vein or its tributaries. These are benign in nature and are composed of smooth muscle cells. A sixty years Normotensive, non-HIV lady presented with right adnexal mass diagnosed as Mature Cystic Teratoma along with adrenal incidentalomas for which laparoscopic adrenalectomy was done and histopathology diagnosis was Leiomyoma. These are more common in immunocompromised patients especially HIV and or EBV infection. Adrenal incidentalomas can have a hormone secreting functions or they can be malignant tumors hence a proper evaluation and treatment should be performed.


2019 ◽  
Vol 9 (1) ◽  
pp. 1508-1510
Author(s):  
Aasiya Rajbhanari ◽  
Usha Manandhar

Mature cystic teratomas are frequently encountered neoplasms of the ovary that comprise of tissues derived from all three germ layers. They are benign neoplasms with malignant transformation noted rarely in around 0.1 to 3% cases. Among the various transformations, malignant melanoma is one of the least commonly encountered. Here, we report a case of 41 years old female with malignant melanoma arising within mature cystic teratoma.


2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Afsaneh Tehranian ◽  
Akram Ghahghaei-Nezamabadi ◽  
Akram Seifollahi ◽  
Sara Kasraei ◽  
Hamideh Dehghani-Nejad ◽  
...  

Abstract Background Mature Cystic Teratoma (MCT) is a benign tumor that can lead to malignant transformation (MT) in 1–3% of cases. Management of MT is a big challenge for gynecologic oncologists due to the lack of specific diagnostic and treatment protocols. Case presentation We reported two Iranian cases of MT of MCT with two different stages and prognosis. Our both cases presented the same symptoms, including chronic abdominal pain and distention, loss of appetite, and weight loss. In case number 1, despite the large size of the tumor, the disease was at stage Ia and had a good prognosis; while, case number 2 was at stage IIIc of the disease with a poor prognosis. Conclusion The stage of the disease is the most important prognostic factor, and early diagnosis and treatment are very critical for better survival.


2021 ◽  
Vol 22 (5) ◽  
pp. 2436
Author(s):  
Kohei Nakamura ◽  
Eriko Aimono ◽  
Reika Takamatsu ◽  
Shigeki Tanishima ◽  
Tomonari Tohyama ◽  
...  

Ovarian mature cystic teratomas comprise tissues derived from all three germ layers. In rare cases, malignant tumors arise from ovarian mature cystic teratoma. A variety of tumors can arise from mature cystic teratoma, among which primary malignant melanoma (MM), for which no molecular analyses such as genomic sequencing have been reported to date, is exceedingly rare, thereby limiting possible therapeutic options using precision medicine. We used targeted gene sequencing to analyze the status of 160 cancer-related genes in a patient with MM arising from an ovarian mature cystic teratoma (MM-MCT). KRAS amplification and homozygous deletion in PTEN and RB1 were detected in tumor samples collected from the patient. No KRAS amplification has been previously reported in cutaneous MM, indicating that the carcinogenesis of MM-MCT differs from that of primary cutaneous melanomas. A better understanding of the underlying genetic mechanisms will help clarify the carcinogenesis of MM-MCT. In turn, this will enable treatment with novel targeting agents as well as the initial exploration of gene-based precision oncological therapies, which aim to improve treatment outcomes for patients with this disease.


1990 ◽  
Vol 10 (6) ◽  
pp. 1033-1035 ◽  
Author(s):  
Ricardo Drut ◽  
Rosa Mónica Drut ◽  
Francisco Vollaro

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