scholarly journals Treatment Outcome of Tuberculosis Patients at Enfraz Health Center, Northwest Ethiopia: A Five-Year Retrospective Study

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Mengistu Endris ◽  
Feleke Moges ◽  
Yeshambel Belyhun ◽  
Eleni Woldehana ◽  
Ahmed Esmael ◽  
...  
Keyword(s):  
Treatment Outcome ◽  
Health Center ◽  
Treatment Success ◽  
Extrapulmonary Tuberculosis ◽  
Northwest Ethiopia ◽  
Tuberculosis Patients ◽  
Successful Treatment Outcome ◽  
Tb Treatment ◽  
Associated Risk Factors ◽  
Study Participants

Objectives.The aim of this study was to assess treatment outcome and associated risk factors among TB patients registered for anti-TB treatment at Enfraz health center, northwest Ethiopia.Methods. A five-year retrospective data (2007–2011) of tuberculosis patients (n=417) registered for anti-TB treatment at Enfraz health center, northwest Ethiopia, were reviewed. Tuberculosis outcomes were following the WHO guidelines. Data were entered and analyzed using SPSS version 20.Results. Among 417 study participants, 95 (22.8%), 141 (33.8%), and 181 (43.4%) were smear-positive, smear-negative, and extrapulmonary tuberculosis patients, respectively. Of the 417 study participants, 206 (49.4%) were tested for HIV. The TB-HIV coinfection was 24/206 (11.7%). Seventeen study participants (4.2%) were transferred to other health facilities. Among the 400 study participants, 379 (94.8%) had successful treatment outcome (302 treatment completed and 77 cured). The overall death, default, and failure rates were 3.4%, 0.5%, and 1.2%, respectively. There was no significant association between sex, age, residence, type of TB, HIV status, and successful TB treatment outcome.Conclusion. Treatment outcome of patients who attended their anti-TB treatment at Enfraz health center was successful. Therefore, this treatment success rate should be maintained and strengthened to achieve the millennium development goal.

scholarly journals Treatment Outcome and Associated Factors among Tuberculosis Patients in Debre Tabor, Northwestern Ethiopia: A Retrospective Study

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Addisu Melese ◽  
Balew Zeleke ◽  
Biniam Ewnete
Keyword(s):  
Treatment Outcome ◽  
Treatment Outcomes ◽  
Health Center ◽  
Successful Treatment ◽  
Associated Factors ◽  
Northwest Ethiopia ◽  
Tuberculosis Control ◽  
Tuberculosis Patients ◽  
Successful Treatment Outcome ◽  
Debre Tabor

Background. Assessing the outcomes of tuberculosis (TB) treatment is an important indicator for evaluation of the effectiveness of tuberculosis control programs. In Ethiopia, directly observed treatment short course (DOTS) was included in the national tuberculosis control program as a strategy but little is known about its effectiveness in the study area. Therefore, this study was aimed at assessing the treatment outcomes of TB patients and associated factors in Debre Tabor, northwest Ethiopia.Methods.A retrospective study was conducted among TB patients for the period from May 2008 to April 2013 at Debre Tabor Health Center, northwest Ethiopia. Data were entered and analyzed using SPSS version 20.0. Descriptive statistics were used to generate frequency tables and figures. Logistic regressions were used to identify factors associated with treatment outcomes atPvalue ≤ 0.05.Results.Out of 339 patients (197 males and 142 females) registered for antituberculosis treatment in Debre Tabor Health Center, only 303 patients were included in the treatment outcome analysis and 87.1% had successful treatment outcome while 12.9% had unsuccessful treatment outcome. In the multivariate logistic regression analysis, the odds of successful treatment outcome were higher among patients ≥45 years of age (AOR=3.807, 95% CI: 1.155–12.544) and lower among females (AOR=0.347, 95% CI: 0.132–0.917), rural residents (AOR=0.342, 95% CI: 0.118–0.986), and negative smear result at the second month of treatment (AOR=0.056, 95% CI: 0.005–0.577) as compared to their counterparts.Conclusion.The treatment outcome of all forms of tuberculosis patients in Debre Tabor health center was satisfactory as expected from effective implementation of DOTS. Although the observed successful treatment outcome was in agreement with the national target, follow-up of patients during the course of treatment to trace the treatment outcomes of transferred-out patients and assessment of other potential sociodemographic factors that could affect the treatment outcomes of TB patients were also recommended.

scholarly journals Treatment outcome of tuberculosis patients at Debretabor General Hospital, Amhara, Northwest Ethiopia

2019 ◽  
Author(s):  
Tesfaye Andualem ◽  
Wubet Taklual
Keyword(s):  
Treatment Outcome ◽  
Pulmonary Tuberculosis ◽  
Success Rate ◽  
General Hospital ◽  
Treatment Success ◽  
Control Program ◽  
Northwest Ethiopia ◽  
Treatment Success Rate ◽  
Tuberculosis Patients ◽  
Good Treatment Outcome

Abstract Introduction Tuberculosis is still a global health problem. Especially, in developing countries where overcrowded and lack of awareness is existed. According to WHO, to monitor the effectiveness of tuberculosis prevention and control program, assessing tuberculosis outcome is important. The aim of this study was to determine treatment outcome of tuberculosis patients in Debretabor General Hospital, Debretabor, Northwest Ethiopia, 2019. Materials and methods A retrospective study was carried out between December 2016 to December 2018 from TB patients attending the health institutions of Debretabor General Hospital. All tuberculosis cases reported between 2016-2018 were reviewed carefully and analyzed. A total of 455 Tb patients were enrolled in this study and data were coded and entered in to the computer for statistical analysis using SPSS version 20 and Epi-info soft wares. Result and Discussion Within the study period a total of 455 study participants were requireted. Tuberculosis type was categorized as 88(18.0%) were smear positive pulmonary tuberculosis, 192(42.2%) were smear negative pulmonary tuberculosis and 181(39.8%) were extra pulmonary tuberculosis. Among the study subjects 86(18.9%) were HIV seropositive. Of the total study subjects, treatment completed (357)78.5%, cured (57)12.%, death (16)3.5%, treatment failure(4)0.9%, transfer out (21)4.6%. Good proportion of TB treatment success rate was in 15-44 yrs 310/326(95.0%) where as poor treatment success rate was in 0-14 years 26/42 (61.9%). Being an urban also has a high treatment success rate310/325(95.4%). 408(89.7%) were successfully treated. Conclusion The treatment success rate of tuberculosis patients was satisfactory 89.7%. In the study, treatment of HIV-TB co-infection need a better attention for good treatment outcome.

scholarly journals Analysis of Treatment Outcome in Patients with Tuberculosis in War Affected Region of Khyber Paktunkhwa, Pakistan

2019 ◽  
Author(s):  
TAUSEEF AHMAD ◽  
Muhammad Ayub Jadoon ◽  
Muhammad Khan ◽  
Muhammad Mumtaz Khan ◽  
Akbar Hussain ◽  
...  
Keyword(s):  
Treatment Outcome ◽  
Success Rate ◽  
Successful Treatment ◽  
Treatment Success ◽  
Case Fatality ◽  
Treatment Success Rate ◽  
Control Programs ◽  
Successful Treatment Outcome ◽  
Tb Treatment ◽  
Treatment Category

Abstract ABSTRACT Background Globally, tuberculosis (TB) remains the leading cause of death from a single infectious disease. TB treatment outcome is an indicator for the effectiveness of a national TB control programs. This study aimed to assess treatment outcome of TB patients and its determinants in Batkhela, Khyber Pakhtunkhwa, Pakistan. Methods A retrospective cohort study was designed using all TB patients who were enrolled at District Head Quarter (DHQ) Hospital Batkhela, Pakistan. Distribution of TB types, treatment outcome and associated factor with successful treatment was computed using SPSS version 20.0 software for windows. Results A total of 515 TB patients were registered, of which 237 (46%) were males and 278 (53.98%) females. Of the total, 234 (45.44%) were cured and 210 (40.77%) completed treatment with overall treatment success rate was 444 (86.21%). Age 0-20 years (AOR= 3.47; 95% CI= 1.54-7.81; P= 0.003), smear-positive pulmonary TB (SPPTB) (AOR= 3.58; 95% CI= 1.89-6.78; P= <0.001), treatment category (AOR= 4.71; 95% CI= 1.17-18.97; P= 0.029), and year of enrollment 2012 (AOR= 6.26; 95% CI= 2.52-15.59; P= <0.001) were significantly associated with successful treatment outcome. Conclusions The overall treatment success rate is satisfactory but still need to be improved to achieve the international targeted treatment outcome. An increase was observed in overall case-fatality rate during the study duration which is an alarming signal for public health.

scholarly journals Treatment outcomes of drug-susceptible tuberculosis and its predictors among male prison inmates in Bauchi State, Nigeria, 2014-2018

2019 ◽  
Author(s):  
Peter Okpeh Amede ◽  
Elizabeth Adedire ◽  
Aishat Usman ◽  
Celestine A. Ameh ◽  
Faruk S. Umar ◽  
...  
Keyword(s):  
Treatment Outcome ◽  
Treatment Outcomes ◽  
Tracking System ◽  
Treatment Success ◽  
Incidence Rates ◽  
Prison Inmates ◽  
Successful Treatment Outcome ◽  
Tb Treatment ◽  
Hiv Negative

Abstract Background: Tuberculosis (TB) is a contagious disease and its transmissibility potential is increased in congregate settings like the prisons. TB incidence rates are five to fifty times higher among prison inmates than the general population which has a direct impact on the outcome of TB treatment. There is paucity of information on TB treatment outcomes and its predictors in Nigerian prisons. We therefore assessed TB treatment outcomes among prison inmates in Bauchi State, Nigeria. Method: We conducted a retrospective data analysis of inmates with TB in the five main prisons in Bauchi State. We extracted sociodemographic, clinical and treatment outcome characteristics from TB treatment register of inmates treated for TB between January 2014 and December 2018, using a standardized checklist. We estimated the TB treatment success rate (TSR) and explored the relationship between the TSR and sociodemographic and clinical characteristics. Related variables were modelled in multivariate logistic regression to identify predictors of TSR at 5% level of significance. Results: All 216 inmates were male with mean age of 37.6±11.4 years. Seventy-six (35.2%) were cured, 61 (28.2%) completed treatment, 48 (22.2%) were lost to follow-up, 17 (7.9%) were transferred out without evaluation and 14 (6.5%) died. Overall TSR was 72.9%. Odds of successful treatment outcome were age; 20-29 years (AOR=10.5; 95% CI: 3.2-35.1), 30-39 years (AOR=4.2; 95% CI: 1.3-13.1), pretreatment weight; 50-59 kg (AOR= 9.6; 95% CI: 1.4-65.6), ≥60 kg (AOR= 18.6; 95% CI: 2.5-140.1) and being HIV negative (AOR=3.3; 95% CI:1.4-7.8). Conclusion: The predictors of successful TB treatment outcome were being less than 40 years of age, having a pretreatment body weight of or greater than 50 kg, imprisonment for less than 2 years, and being HIV negative. We recommended that to improve TB TSR among prison inmates; age, duration of imprisonment, weight and TB/HIV coinfection should be the major consideration during drugs adherence, psychological and nutritional counselling and a tracking system be developed by the prisons authority to follow-up inmates transferred-out to other health facilities to ensure they complete the treatment and outcomes evaluated. Key words: Tuberculosis, Treatment outcomes, Prison inmates, Predictors, Bauchi State, Nigeria

scholarly journals Treatment outcomes of drug-susceptible tuberculosis and its predictors among male prison inmates in Bauchi State, Nigeria, 2014-2018

2020 ◽  
Author(s):  
Peter Okpeh Amede ◽  
Elizabeth Adedire ◽  
Aishat Usman ◽  
Celestine A. Ameh ◽  
Faruk S. Umar ◽  
...  
Keyword(s):  
Treatment Outcome ◽  
Treatment Outcomes ◽  
Tracking System ◽  
Treatment Success ◽  
Incidence Rates ◽  
Prison Inmates ◽  
Successful Treatment Outcome ◽  
Tb Treatment ◽  
Hiv Negative

Abstract Background : Tuberculosis (TB) is a contagious disease and its transmissibility potential is increased in congregate settings like the prisons. TB incidence rates are five to fifty times higher among prison inmates than the general population which has a direct impact on the outcome of TB treatment. There is paucity of information on TB treatment outcomes and its predictors in Nigerian prisons. We therefore assessed TB treatment outcomes among prison inmates in Bauchi State, Nigeria. Method: We conducted a retrospective data analysis of inmates with TB in the five main prisons in Bauchi State. We extracted sociodemographic, clinical and treatment outcome characteristics from TB treatment register of inmates treated for TB between January 2014 and December 2018, using a standardized checklist. We estimated the TB treatment success rate (TSR) and explored the relationship between the TSR and sociodemographic and clinical characteristics. Related variables were modelled in multiple logistic regression to identify predictors of TSR at 5% level of significance. Results: All 216 inmates were male with mean (SD) age of 37.6±11.4 years. Seventy-six (35.2%) were cured, 61 (28.2%) completed treatment, 48 (22.2%) were lost to follow-up, 17 (7.9%) were transferred out without evaluation and 14 (6.5%) died. Overall TSR was 72.9%. Predictors of successful treatment outcome were age; 20-29 years (AOR=10.5; 95% CI: 3.2-35.1), 30-39 years (AOR=4.2; 95% CI: 1.3-13.1), pretreatment weight; ≥ 55kg (AOR= 13.3; 95% CI: 6.0-29.6), imprisonment for ≤ 2 years (AOR= 2.6; 95% CI: 1.3-5.4) and being HIV negative (AOR=3.3; 95% CI:1.4-7.8). Conclusion: The predictors of successful TB treatment outcome were being less than 40 years of age, having a pretreatment body weight of or greater than 55 kg, imprisonment for less than 2 years, and being HIV negative. We recommended that to improve TB TSR among prison inmates; age, duration of imprisonment, weight and TB/HIV co-infection should be the major consideration during pretreatment, psychological and nutritional counselling and a tracking system be developed by the prisons authority to follow-up inmates transferred-out to other health facilities to ensure they complete the treatment and outcomes evaluated.

scholarly journals Outcome of Tuberculosis patients under directly observed short course treatment in western Ethiopia

2015 ◽  
Vol 9 (07) ◽  
pp. 752-759 ◽  
Author(s):  
Eyasu Ejeta ◽  
Muda Chala ◽  
Gebeyaw Arega ◽  
Kassahu Ayalsew ◽  
Lensa Tesfaye ◽  
...  
Keyword(s):  
Treatment Outcome ◽  
Success Rate ◽  
Treatment Success ◽  
World Health ◽  
Treatment Success Rate ◽  
Important Indicator ◽  
Tuberculosis Patients ◽  
Study Participants ◽  
Western Ethiopia

Introduction: Treatment outcome is an important indicator of tuberculosis control programs, as suggested by the World Health Organization. However, this has not been well documented in the study area. This work contributes to a better understanding this issue. Methodology: A five-year (2009–2013) retrospective cohort study was conducted between April and May 2014, in six randomly selected health institutions providing tuberculosis treatment in western Ethiopia. Bivariate and multivariate logistic regression analyses were used to assess the association between treatment outcomes and predictor variables. Results: A total of 1,175 tuberculosis patients with a mean (standard deviation) age of 29.91 (13.99) were involved in the study. The majority of the study participants had smear-negative pulmonary tuberculosis (39.7%) and extrapulmonary tuberculosis (39.7%). Of all the study participants, 14.5% were cured, 56.3% completed treatment, 0.2% had treatment failure, 8.1% died during follow-up, 7.1% were reported as defaulters, and 13.8% were transferred out to another health institution. The overall treatment success rate was 70.8% and show progressive increases over the course of the study. The associated predictors were enrollment years, HIV co-infection, and sputum smear follow-up in the second, fifth, and seven months. Conclusions: The treatment success rate was unsatisfactory in spite of improvement seen over the study period. Thus, continued follow-up of patients, with frequent supportive supervision during the course of treatment, and provision of early detection and follow-up for HIV infection need to be strengthened to achieve an effective treatment outcome.

scholarly journals Treatment outcome of tuberculosis patients at Adare general Hospital, Hawassa, Southern Ethiopia. (A five year retrospective study)

2019 ◽  
Author(s):  
Bezunesh Tsegaye ◽  
Zufan Bedewi ◽  
Solomon Lemma Asnake
Keyword(s):  
Treatment Outcome ◽  
Retrospective Study ◽  
Treatment Outcomes ◽  
General Hospital ◽  
Treatment Success ◽  
Southern Ethiopia ◽  
P Value ◽  
Tuberculosis Patients ◽  
Tb Treatment ◽  
Extra Pulmonary

Abstract Background Globally still Tuberculosis remains a major public health problems and socio-economic issue in the 21st century. Ethiopia is among the countries most heavily affected by Tuberculosis, where it is the leading cause of morbidity, the third cause of hospital admission and the second cause of death. To improve Tuberculosis management and control, early detection of cases, effective treatment and persistent evaluation of treatment outcome are vital issues that should be taken into consideration. Hence, this study was designed to determine treatment outcomes and associated risk factors among TB patients registered and receiving anti-TB treatment at Adare general Hospital, Southern Ethiopia. Methods A five years retrospective study was conducted by reviewing medical records of TB patients at Adare general Hospital. A total of 1151 Tuberculosis patients’ cards registered from (September 2013 to August 2017) for treatment at TB clinic were reviewed. Data was coded, cleaned and entered into Microsoft Excel sheet then ported and analyzed using SPSS version 20 statistical soft ware. Logistic regression with odds ratios (OR) along with the 95% confidence interval was computed and interpreted. A P value <0.05 was declared as statistically significant. Result Among 1122 cases 620 (55.3%) were male, 748(66.7%) were from urban areas, 319 (28.4%) were smear positive, 352 (31.4%) were smear negative and 451 (40.2%) were extra pulmonary patients. Of the 1122 284 (25.3%) were cured, 753(67.1%) completed treatment, 29(2.6%) defaulted, 53(4.7%) died and 3 (0.3%) had treatment failure. The mean treatment success rate was 92.4%. The risk of unsuccessful TB treatment outcome was significantly higher among TB patients from rural areas (AOR = 0.43, 95% CI: 0.27, 0.67); patients with extra pulmonary TB (AOR = 0.87, 95% CI; 0.67, 1.14), and HIV positive TB patients (AOR = 5.47, 95% CI; 3.47, 8.63) were more likely to have poor treatment outcomes as compared to their counter parts. Conclusion The treatment success rates of Tuberculosis, at Adare hospital was comparable to national health facility level coverage, but it should be maintained and strengthen further to attain tuberculosis related national and millennium goal.

scholarly journals Seroprevalence of AsymptomaticLeishmania donovaniamong Laborers and Associated Risk Factors in Agricultural Camps of West Armachiho District, Northwest Ethiopia: A Cross-Sectional Study

2018 ◽  
Vol 2018 ◽  
pp. 1-8
Author(s):  
Animen Ayehu ◽  
Yibeltal Aschale ◽  
Wossenseged Lemma ◽  
Animut Alebel ◽  
Ligabaw Worku ◽  
...  
Keyword(s):  
Risk Factors ◽  
Leishmania Donovani ◽  
Public Health Problem ◽  
Cross Sectional Study ◽  
Northwest Ethiopia ◽  
Control Measures ◽  
Sectional Study ◽  
Cross Sectional ◽  
Associated Risk Factors ◽  
Study Participants

Background. Visceral leishmaniasis (VL, also called kala-azar) is a public health problem in Ethiopia, especially in sesame and sorghum growing areas. Compared to other populations, labor migrants are the most exposed. Knowing the seroprevalence ofLeishmania donovaniand associated risk factors is essential to design appropriate control measures. The main aim of this study was to assess the seroprevalence of asymptomaticL. donovaniamong laborers and associated risk factors in agricultural camps of West Armachiho district, Northwest Ethiopia. Therefore, this study was conducted to know the seroprevalence and associated risk factors ofL. donovaniinfection.Method. A cross-sectional study was conducted among 185 laborers from October to December 2017. A simple random sampling technique was used to select study participants from selected agricultural camps. After obtaining written informed consent, data were collected using a structured pretested Amharic version questionnaire using the interview technique. A single finger prick blood sample was collected from the study participants and the blood samples were subjected to the serological diagnostic method using the rk39 kit. The multivariable logistic regression model was used to identify risk factors associated withL. donovaniinfection.Result. Among 185 participants examined using rk39, 14 (7.6%) were seroreactive forL. donovani.Leishmania donovaniinfection had a statistically significant association with sleeping underBalanitestrees (AOR: 4.36, 95%CI: 1.186-16.06), presence of domestic animals near sleeping place (AOR: 4.68, 95% CI: 1.25-17.56), and lack of knowledge about VL transmission (AOR: 3.79, 95% CI: 1.07-13.47).Conclusion. Seroprevalence of asymptomaticL. donovaniamong laborers in agricultural camps of West Armachiho was low. Prevention measures and health education about risk factors that expose toL. donovaniinfection for the laborers are essential to prevent the spread of the disease.

scholarly journals Treatment outcome of tuberculosis at Dilla Referral Hospital, Gedeo Zone, southern Ethiopia: A retrospective study

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0249369
Author(s):  
Endrias Markos Woldesemayat ◽  
Zewtir Azeze
Keyword(s):  
Risk Factors ◽  
Treatment Outcome ◽  
Success Rate ◽  
Treatment Success ◽  
Referral Hospital ◽  
Treatment Success Rate ◽  
Southern Ethiopia ◽  
Hiv Status ◽  
Hospital Data ◽  
Tb Treatment

Background Tuberculosis (TB) is one of the major public health problems in Ethiopia. Determining treatment outcome of TB cases could help to understand the effectiveness of TB control efforts. The objective of this study was to assess TB treatment outcome and associated factors and determine the risk factors of death among TB cases who were on Directly Observed Treatment Short course (DOTS). Methodology We analyzed a retrospective data for TB cases who were on DOTS at Dilla Referral Hospital from July 2011- June 2016. The study population was TB cases with known HIV status and whose treatment outcome was evaluated at the Hospital. Data were entered, cleaned and analyzed using statistical package SPSS for windows, version 20. Result Out of 899 registered TB cases, 731 included in this analysis. Of these cases, 424 (58.0%) were male and 334 (45.7%) were in the age group of below 25 years. Treatment success rate of TB was 675 (92.3%) and death rate was 18 (2.5%). Treatment outcome showed statistically significant variation by HIV status (P < 0.001). HIV status of the TB cases and pretreatment weight were associated with TB treatment outcome. HIV status of the TB cases was associated with death of the TB cases (Adjusted Odds Ratio (AOR) 5.0; CI 95%: 1.8–13.5). Conclusion TB treatment success rate found in this study was high. Patient’s weight and HIV status were associated with treatment outcome. Moreover, HIV status predicted death of TB cases. Cautious treatment follow-up and defaulter tracing mechanisms for TB cases with these risk factors were suggested.

scholarly journals Impact of HIV Status on Treatment Outcome of Tuberculosis Patients Registered at Arsi Negele Health Center, Southern Ethiopia: A Six Year Retrospective Study

PLoS ONE ◽  
2016 ◽  
Vol 11 (4) ◽  
pp. e0153239 ◽  
Author(s):  
Gebreslassie Gebremariam ◽  
Getachew Asmamaw ◽  
Muktar Hussen ◽  
Mengistu Z. Hailemariam ◽  
Demissie Asegu ◽  
...  
Keyword(s):  
Treatment Outcome ◽  
Retrospective Study ◽  
Health Center ◽  
Southern Ethiopia ◽  
Hiv Status ◽  
Tuberculosis Patients
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