scholarly journals Suspected Transfusion Related Acute Lung Injury Improving following Administration of Tranexamic Acid: A Case Report

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Stan Ryniak ◽  
Piotr Harbut ◽  
Anders Östlund ◽  
Andrzej Mysiak ◽  
Jan G. Jakobsson

A 16-year-old woman with craniofacial injury developed severe acute respiratory failure under the primary reconstructive surgical procedure requiring several units of blood and plasma. A transfusion related acute lung injury (TRALI) was suspected and supportive treatment was initiated. Because of the severity of symptoms, acute extracorporeal membrane oxygenation (ECMO) was planned. During preparation for ECMO, a single intravenous dose, 1 g of tranexamic acid, was administered and a remarkable improvement was observed shortly thereafter. The patient was placed on ECMO for 16 hours. The further course was uncomplicated and the patient was discharged from ICU on the 6th day after admission fully and she recovered. A clinical improvement was observed in a timely fashion following the administration of tranexamic acid. The handling of a suspected TRALI and potential benefit from administration of tranexamic acid are discussed in this case report.

2014 ◽  
Vol 9 (1) ◽  
Author(s):  
Julien Teodori ◽  
Kamal Rampersad ◽  
Giovanni Teodori ◽  
Roland Roopchand ◽  
Gianni Davide Angelini

2021 ◽  
Vol 5 ◽  
pp. 18-18
Author(s):  
Alexandra Lucas ◽  
Gopi Mohan ◽  
Amanda Winkler ◽  
Kelly Gardner ◽  
Michael Whalen

2020 ◽  
Vol 52 (9) ◽  
pp. 2849-2853 ◽  
Author(s):  
Izabella Miśkiewicz-Migoń ◽  
Justyna Miśkiewicz-Bujna ◽  
Monika Rosa ◽  
Anna Kubica-Cielińska ◽  
Joanna Bladowska ◽  
...  

2016 ◽  
Vol 8 (1) ◽  
pp. 22-25 ◽  
Author(s):  
KB Prashanth ◽  
S Abhilash

ABSTRACT Objectives This study was conducted to assess the efficacy of the drug tranexamic acid administered preoperatively in controlling the bleeding during tonsillectomy intraoperatively. Materials and methods A total of 50 patients who underwent tonsillectomy were randomized into two groups. Group I (study group): Intravenous tranexamic acid was given with dose of 10 mg/kg. Group II (control group): Tranexamic acid injection was not given. Intraoperative amount of bleeding was assessed in each case. Results The study group had significant reduction in bleeding and the p-value was <0.05, which was statistically significant, when compared to control group. There were no side effects of the drug observed. Conclusion Single intravenous dose of tranexamic acid at a dose of 10 mg/kg preoperatively is effective in control of tonsillectomy bleeding. How to cite this article Santosh UP, Prashanth KB, Abhilash S. A Comparative Study to verify the Efficacy of Preoperative Intravenous Tranexamic Acid in Control of Tonsillectomy Bleeding. Int J Otorhinolaryngol Clin 2016;8(1):22-25.


Transfusion ◽  
2014 ◽  
Vol 54 (12) ◽  
pp. 3088-3091 ◽  
Author(s):  
Graeme R. Quest ◽  
Hilda Gaal ◽  
Gwen Clarke ◽  
Susan Nahirniak

2008 ◽  
Vol 2 (1) ◽  
Author(s):  
Altaf Gauhar Haji ◽  
Shekhar Sharma ◽  
D. K. Vijaykumar ◽  
Jerry Paul

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