scholarly journals Transcutaneous Intraluminal Impedance Measurement for Minimally Invasive Monitoring of Gastric Motility: Validation in Acute Canine Models

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Michael D. Poscente ◽  
Gang Wang ◽  
Dobromir Filip ◽  
Polya Ninova ◽  
Gregory Muench ◽  
...  

Transcutaneous intraluminal impedance measurement (TIIM) is a new method to cutaneously measure gastric contractions by assessing the attenuation dynamics of a small oscillating voltage emitted by a battery-powered ingestible capsule retained in the stomach. In the present study, we investigated whether TIIM can reliably assess gastric motility in acute canine models.Methods. Eight mongrel dogs were randomly divided into 2 groups: half received an active TIIM pill and half received an identically sized sham capsule. After 24-hour fasting and transoral administration of the pill (active or sham), two force transducers (FT) were sutured onto the antral serosa at laparotomy. After closure, three standard cutaneous electrodes were placed on the abdomen, registering the transluminally emitted voltage. Thirty-minute baseline recordings were followed by pharmacological induction of gastric contractions using neostigmine IV and another 30-minute recording. Normalized one-minute baseline and post-neostigmine gastric motility indices (GMIs) were calculated and Pearson correlation coefficients (PCCs) between cutaneous and FT GMIs were obtained. Statistically significant GMI PCCs were seen in both baseline and post-neostigmine states. There were no significant GMI PCCs in the sham capsule test. Further chronic animal studies of this novel long-term gastric motility measurement technique are needed before testing it on humans.

2014 ◽  
Vol 146 (5) ◽  
pp. S-613 ◽  
Author(s):  
Gang Wang ◽  
Michael D. Poscente ◽  
Dobromir Filip ◽  
Orly Yadid-Pecht ◽  
Christopher N. Andrews ◽  
...  

2013 ◽  
Vol 18 (3) ◽  
pp. 46-53 ◽  
Author(s):  
Luiz Filiphe Gonçalves Canuto ◽  
Marcos Roberto de Freitas ◽  
Karina Maria Salvatore de Freitas ◽  
Rodrigo Hermont Cançado ◽  
Leniana Santos Neves

OBJECTIVE: The purpose of this retrospective study was to evaluate long-term stability of maxillary incisors alignment in cases submitted to non-extraction orthodontic treatment. METHODS: The sample comprised 23 patients (13 female; 10 male) at a mean initial age of 13.36 years (SD = 1.81 years), treated with fixed appliances. Dental cast measurements were obtained at three different time points (T1 - pretreatment, T2 - posttreatment and T3 - long-term posttreatment). Variables assessed in maxillary arch were Little Irregularity Index, intercanine, interpremolar and intermolar widths, arch length and perimeter. The statistical analysis was performed by one-way ANOVA and Tukey tests when necessary. Pearson' correlation coefficients were used to investigate possible associations between the evaluated variables. RESULTS: There was no significant change in most arch dimension measurements during and after treatment, however, during the long-term posttreatment period, it was observed a significant maxillary incisors crowding relapse. CONCLUSION: The maxillary incisors irregularity increased significantly (1.52 mm) during long-term posttreatment. None of the studied clinical factors demonstrated to be predictive of the maxillary crowding relapse.


2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Bowen Guan ◽  
Jiayu Wu ◽  
Chao Xie ◽  
Jianhong Fang ◽  
Haile Zheng ◽  
...  

This article intends to study the influence of macrotexture and microtexture on the skid resistance of four types of aggregates. For this purpose, fractal dimension (D), root mean square height (Rq), and Polished Stone Value (PSV) were tested. The Pearson correlation coefficients between PSV and D or Rq in the interval of different polishing cycles were calculated and analyzed with correlation analysis. The relationships between PSV and Rq were also established. The results showed that the PSV development was approximately divided into 3 stages including accelerated attenuation stage, decelerated attenuation stage, and stabilization stage. There is a critical point of the entire polishing cycles. When the number of the polishing cycles exceeds this critical point, microtexture replaces macrotexture to play a major role in the skid resistance of aggregates. In the accelerated attenuation stage, macrotexture plays a major role in the skid resistance of aggregates. In the decelerated attenuation stage and stabilization stage, microtexture gradually plays a major role in the skid resistance of aggregates. Because of roughest microtexture in the stabilization stage, bauxite can provide the highest levels of skid resistance for high friction surface treatment over the long-term period.


2010 ◽  
Vol 26 (11) ◽  
pp. 2059-2067 ◽  
Author(s):  
Marly Augusto Cardoso ◽  
Luciana Yuki Tomita ◽  
Elaine Cristina Laguna

This study describes the validity of a food frequency questionnaire (FFQ) in 93 low-income women (20-65 years), participating in a case-control study in São Paulo, Brazil. Two FFQ (FFQ1 and FFQ2, 12 months apart) and three 24-hour dietary recalls (24hR) were conducted between 2003 and 2004 to estimate dietary intake during the past year. The Pearson correlation coefficients (crude, energy-adjusted and de-attenuated) were used for comparisons between FFQ and 24hR. The agreement between the methods was further examined by the Bland-Altman analysis. For the assessment of long-term reliability, the energy-adjusted intra-class correlation coefficients were mostly around 0.40, but higher for vitamin A and folate (0.50-0.56). Energy-adjusted, attenuation-corrected Pearson validity correlations between FFQ and DR ranged from 0.30-0.54 for macronutrients to 0.20-0.48 for micronutrients, with higher value for calcium (0.75). There were small proportions of grossly misclassified nutrient intakes, while Bland-Altman plots indicated that the FFQ is accurate in assessing nutrient intake at a group level.


2020 ◽  
Author(s):  
Alireza Zimorovat ◽  
Fatemeh Moghtaderi ◽  
Mojgan Amiri ◽  
Hamidreza Raeisi-Dehkordi ◽  
Matin Mohyadini ◽  
...  

Abstract Background: To the best of our knowledge, no study has tried to develop and validate a multiple-choice food-based FFQ in Iran using weighed dietary records.This study aimed to investigate the validity and reproducibility of a multiple-choice semi-quantitative food frequency questionnaire (SQ-FFQ) in adults living in central Iran.Methods: Participants attended a large long-term clinical trial were asked to complete three SQ-FFQs by interview, and nine 3-day weighed dietary records (WDRs), over nine months. They provided two blood samples to assess serum calcium, magnesium, zinc, and vitamin C levels. The Pearson and intraclass correlation coefficients (ICC) were calculated to assess reproducibility and validity. The degree of misclassification was explored by using a contingency table of quartiles which is compare the information between third FFQ and WDRs. The method of triads was incorporated to assess validity coefficients between estimated intakes using third FFQ, WDRs, and biochemical markers and assumed true intakes.Results: A total of 180 adults aged 48.9±8.4 years completed the study. Compared to WDRs, FFQs overestimated all nutrients intakes except for iron. The median Pearson correlation coefficient was 0.31, 0.44, and 0.38 for FFQ1-FFQ2, FFQ1-FFQ3 and FFQ2-FFQ3, respectively and ICC ranged from 0.43 (thiamin) to 0.73 (vitamin D, median: 0.56). The de-attenuated, age, sex, and education adjusted correlation coefficients ranged from 0.01 for vitamin A to 0.40 for vitamin B12 and -0.05 for vitamin A to 0.41 for manganese (median: 0.17 and 0.26) for FFQ1-WDR and FFQ3-WDR, respectively. The median exact agreement and complete disagreement between FFQ3 and WDRs were 33% and 6%, respectively. The FFQ3 validity coefficients for vitamin C, calcium, magnesium, and zinc were 0.13, 0.62, 0.89, and 0.66, respectively, using the triads method.Conclusions: The SQ-FFQ seems to be an acceptable tool to assess the long-term dietary intake for future large-scale studies in this population.


2021 ◽  
Author(s):  
Andrew I Geller ◽  
Daniel S Budnitz ◽  
Heather Dubendris ◽  
Radhika Gharpure ◽  
Minn Minn Soe ◽  
...  

Monitoring COVID-19 vaccination coverage among nursing home (NH) residents and staff is important to ensure high coverage and guide patient-safety policies. With the termination of the federal Pharmacy Partnership for Long-Term Care Program, another source of facility-based vaccination data is needed. We compared numbers of COVID-19 vaccinations administered to NH residents and staff reported by pharmacies participating in the temporary federal Pharmacy Partnership for Long-Term Care Program with those reported by NHs participating in new COVID-19 vaccination modules of CDC's National Healthcare Safety Network (NHSN). Pearson correlation coefficients comparing the number vaccinated between the two approaches were 0.89, 0.96, and 0.97 for residents and 0.74, 0.90, and 0.90 for staff, in the weeks ending January 3, 10, and 17, respectively. Based on subsequent NHSN reporting, vaccination coverage with ≥1 vaccine dose reached 77% for residents and 50% for staff the week ending January 31 and plateaued through April 2021.


2020 ◽  
Author(s):  
Alireza Zimorovat ◽  
Fatemeh Moghtaderi ◽  
Mojgan Amiri ◽  
Hamidreza Raeisi-Dehkordi ◽  
Matin Mohyadini ◽  
...  

Abstract Background: To the best of our knowledge, no study has tried to develop and validate a multiple-choice food-based FFQ in Iran using weighed dietary records.This study aimed to investigate the validity and reproducibility of a multiple-choice semi-quantitative food frequency questionnaire (SQ-FFQ)in adults living in central Iran.Methods: Participants attended a large long-term clinical trial were asked to complete three SQ-FFQs by interview, and nine 3-day weighed dietary records (WDRs), over nine months.They provided two blood samples to assess serum calcium, magnesium, zinc, and vitamin C levels.The Pearson and intraclass correlation coefficients (ICC) were calculated to assess reproducibility and validity. The degree of misclassification was explored by using a contingency table of quartiles which is compare the information between third FFQ and WDRs. The method of triads was incorporated to assess validity coefficients between estimated intakes using third FFQ, WDRs, and biochemical markers and assumed true intakes.Results: A total of180 adults aged 48.9±8.4 years completed the study. Compared to WDRs, FFQs overestimated all nutrients intakes except for iron. The median Pearson correlation coefficient was 0.31, 0.44, and 0.38 for FFQ1-FFQ2, FFQ1-FFQ3 and FFQ2-FFQ3, respectively andICC ranged from 0.43 (thiamin) to 0.73 (vitamin D, median: 0.56). The de-attenuated, age, sex, and education adjusted correlation coefficients ranged from 0.01 for vitamin A to 0.40 for vitamin B12 and -0.05 for vitamin A to 0.41 for manganese (median: 0.17 and 0.26) for FFQ1-WDR and FFQ3-WDR, respectively.The medianexact agreement and complete disagreement between FFQ3 and WDRs were 33% and 6%, respectively.The FFQ3validity coefficientsfor vitamin C, calcium, magnesium, and zinc were 0.13, 0.62, 0.89, and 0.66, respectively, using the triads method.Conclusions: The SQ-FFQseems to be an acceptable tool to assess the long-term dietary intake for future large-scale studies in this population.


2020 ◽  
Vol 29 (3) ◽  
pp. 429-435
Author(s):  
Patricia C. Mancini ◽  
Richard S. Tyler ◽  
Hyung Jin Jun ◽  
Tang-Chuan Wang ◽  
Helena Ji ◽  
...  

Purpose The minimum masking level (MML) is the minimum intensity of a stimulus required to just totally mask the tinnitus. Treatments aimed at reducing the tinnitus itself should attempt to measure the magnitude of the tinnitus. The objective of this study was to evaluate the reliability of the MML. Method Sample consisted of 59 tinnitus patients who reported stable tinnitus. We obtained MML measures on two visits, separated by about 2–3 weeks. We used two noise types: speech-shaped noise and high-frequency emphasis noise. We also investigated the relationship between the MML and tinnitus loudness estimates and the Tinnitus Handicap Questionnaire (THQ). Results There were differences across the different noise types. The within-session standard deviation averaged across subjects varied between 1.3 and 1.8 dB. Across the two sessions, the Pearson correlation coefficients, range was r = .84. There was a weak relationship between the dB SL MML and loudness, and between the MML and the THQ. A moderate correlation ( r = .44) was found between the THQ and loudness estimates. Conclusions We conclude that the dB SL MML can be a reliable estimate of tinnitus magnitude, with expected standard deviations in trained subjects of about 1.5 dB. It appears that the dB SL MML and loudness estimates are not closely related.


Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1088-P
Author(s):  
PEILI WANG ◽  
RAMANAIAH MAMILLAPALLI ◽  
WANLING ZHU ◽  
OWEN CHAN

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