scholarly journals Hypersensitivity and the Working Environment for Allergy Nurses in Sweden

2014 ◽  
Vol 2014 ◽  
pp. 1-7
Author(s):  
Pia Kalm-Stephens ◽  
Therese Sterner ◽  
Kerstin Kronholm Diab ◽  
Greta Smedje
Keyword(s):  
Allergic Diseases ◽  
Working Environment ◽  
National Guidelines ◽  
Allergen Specific Immunotherapy ◽  
Exhaust Ventilation ◽  
Provocation Tests ◽  
History Of ◽  
Challenge Tests ◽  
Skin Prick Tests ◽  
Personnel Safety

Background. Allergy nurses are exposed to allergens and respiratory irritants, and there are no national guidelines addressing personnel safety when working with these agents. Objective. To investigate the prevalence of allergies, asthma, and hypersensitivity symptoms among allergy nurses and the use of protective equipment and measures when working with allergen concentrates and respiratory irritants. Methods. A questionnaire survey was performed among the members of the Swedish Association of Allergy Nurses. Results. Diagnosed asthma was reported by 17%, while 18% had allergy to pets, 28% had allergy to pollens, and 26% reported nasal symptoms. Fifty-one percent reported a history of asthma, allergic diseases, or hypersensitivity symptoms in their family. Exhaust ventilation was used by 24% during skin prick tests, 17% during allergen specific immunotherapy, and 33% when performing methacholine challenge tests. Tightly closed containers for disposable waste were used by 58% during skin prick tests, by 60% during immunotherapy, and by 40% during Pc provocation tests. Conclusion. Allergy nurses had a tendency to increased prevalence of lower respiratory symptoms, asthma, and allergic rhinitis and more than half of the nurses had a family history of asthma, allergic diseases, or hypersensitivity symptoms. Additional studies are needed to evaluate the validity of these results.

СОХРАНЕНИЕ ПРИВЕРЖЕННОСТИ К ТЕРАПИИ КАК ГАРАНТИЯ ЭФФЕКТИВНОСТИ СЛИТ

2019 ◽  
Author(s):  
K.S. Pavlova ◽  
D.S. Mdinaradze
Keyword(s):  
Allergic Diseases ◽  
Atopic Asthma ◽  
National Guidelines ◽  
Allergen Specific Immunotherapy ◽  
Dose Dependent ◽  
Methods Of Treatment ◽  
Choice Of Therapy ◽  
Dose Dependent Effect ◽  
Reduced Adherence

По данным ВОЗ, рекомендации врача выполняют не более 50 пациентов. В конечном итоге это приводит к снижению или отсутствию эффекта от назначаемого лечения. В связи с этим во всех последних международных и национальных руководствах говорится о необходимости учета предпочтений пациента при выборе терапии. Аллерген-специфическая иммунотерапия (АСИТ) является одним из основных методов лечения аллергических заболеваний, таких как аллергический ринит, конъюнктивит и атопическая бронхиальная астма, обладает болезнь-модифицирующими свойствами и долгосрочным эффектом после окончания лечения. АСИТ относится к профилактическому и продолжительному методу (рекомендовано на протяжении не менее 3 лет), что часто является причиной снижения приверженности к терапии. В различных исследованиях подтвержден зависимый от дозы аллергена эффект АСИТ, а следовательно, изменение режимов или сокращение сроков терапии могут влиять на конечный результат. При недостаточной эффективности АСИТ необходимо в первую очередь рассматривать вероятность низкого комплаенса. Сублингвальная АСИТ (СЛИТ) требует от пациента высокой вовлеченности в процесс лечения. Задачей врача в данном случае становится повышение терапевтического сотрудничества как одного из важнейших факторов обеспечения эффективности СЛИТ. Основными способами в данном случае являются улучшение понимания пациентом цели терапии и регулярный контроль со стороны врача.According to WHO at last 50 of the patient dont follow doctors recommendations. Ultimately, this leads to a decrease or absence of the treatment effect. In this regard, all the latest international and national guidelines mention the need to take into account the patients preferences in the choice of therapy. Allergen-specific immunotherapy (AIT) is one of the main methods of treatment of allergic diseases such as allergic rhinitis, allergic conjunctivitis and atopic asthma, and has disease modifying properties and the long-term efficacy after stop treatment. AIT refers to a preventive and long-term method (recommended for at least 3 years), that is often the cause of reduced adherence to therapy. Various studies have confirmed the dose-dependent effect of AIT, and, consequently, changes in regimens or shortening of therapy may affect the end result. In case of insufficient effectiveness of AIT, the probability of low compliance should be considered first of all. Sublingual AIT (SLIT) requires the patient to be highly involved in the treatment process. The task of the doctor in this case is increasing therapeutic cooperation, as one of the most important factors to ensure the effectiveness of SLIT. The main methods in this case are to improve the patients understanding of the purpose of the therapy and regular monitoring by the doctor.

Immunotheraphy in Allergic Diseases

2018 ◽  
Vol 24 (11) ◽  
pp. 1174-1194
Author(s):  
Albert Roger ◽  
Maria Basagana ◽  
Aina Teniente-Serra ◽  
Nathalie Depreux ◽  
Yanina Jurgens ◽  
...  
Keyword(s):  
Specific Immunotherapy ◽  
Allergic Diseases ◽  
Specific Ige ◽  
World Population ◽  
Allergen Specific Immunotherapy ◽  
Routes Of Administration ◽  
Disease Modifying Therapy ◽  
History Of ◽  
Ige Mediated ◽  
Special Case

The prevalence of allergic diseases is increasing worldwide. It is estimated that more than 30% of the world population is now affected by one or more allergic conditions and a high proportion of this increase is in young people. The diagnosis of allergy is dependent on a history of symptoms on exposure to an allergen together with the detection of allergen-specific IgE. Accurate diagnosis of allergies opens up therapeutic options. Allergen specific immunotherapy is the only successful disease-modifying therapy for IgE-mediated allergic diseases. New therapeutic strategies have been developed or are currently under clinical trials. Besides new routes of administration, new types of allergens are being developed. The use of adjuvants may amplify the immune response towards tolerance to the antigens. In this review, we analyze different antigen-specific immunotherapies according to administration route, type of antigens and adjuvants, and we address the special case of food allergy.

scholarly journals Retention adherence to therapy as a guarantee of the SLIT efficacy

2019 ◽  
Vol 16 (2) ◽  
pp. 61-66
Author(s):  
K S Pavlova ◽  
D S Mdinaradze
Keyword(s):  
Allergic Diseases ◽  
Atopic Asthma ◽  
National Guidelines ◽  
Allergen Specific Immunotherapy ◽  
Dose Dependent ◽  
Methods Of Treatment ◽  
Choice Of Therapy ◽  
Dose Dependent Effect ◽  
Adherence To Therapy

According to WHO at last 50% of the patient don't follow doctor’s recommendations. Ultimately, this leads to a decrease or absence of the treatment effect. In this regard, all the latest international and national guidelines mention the need to take into account the patient’s preferences in the choice of therapy. Allergen-specific immunotherapy (AIT) is one of the main methods of treatment of allergic diseases such as allergic rhinitis, allergic conjunctivitis and atopic asthma, and has disease modifying properties and the long-term efficacy after stop treatment. AIT refers to a preventive and long-term method (recommended for at least 3 years), that is often the cause of reduced adherence to therapy. Various studies have confirmed the dose-dependent effect of AIT, and, consequently, changes in regimens or shortening of therapy may affect the end result. In case of insufficient effectiveness of AIT, the probability of low compliance should be considered first of all. Sublingual AIT (SLIT) requires the patient to be highly involved in the treatment process. The task of the doctor in this case is increasing therapeutic cooperation, as one of the most important factors to ensure the effectiveness of SLIT. The main methods in this case are to improve the patient’s understanding of the purpose of the therapy and regular monitoring by the doctor.

scholarly journals Food allergy in early childhood increases the risk of pollen-food allergy syndrome

2022 ◽  
Author(s):  
Kun Baek Song ◽  
Min Jee Park ◽  
Eom Ji Choi ◽  
Sungsu Jung ◽  
Ji-Sun Yoon ◽  
...  
Keyword(s):  
Early Childhood ◽  
Food Allergy ◽  
Birth Cohort ◽  
Age At Onset ◽  
Allergic Diseases ◽  
Population Based ◽  
Food Allergens ◽  
History Of ◽  
Skin Prick Tests ◽  
Inhalant Allergens

Abstract Background: The level of pollen in Korea has increased over recent decades. Research suggests that pollen-food allergy syndrome (PFAS) may be more frequent in childhood than previously recognized. We aimed to investigate the prevalence and characteristics of PFAS in children aged 6–10 years from a general population-based birth cohort. Methods: We analyzed 930 children from the COhort for Childhood Origin of Asthma and allergic diseases (COCOA) birth cohort. Allergic diseases were diagnosed annually by pediatric allergists. The skin prick tests were performed with 14 common inhalant allergens and four food allergens for children aged 3 and 7 years. Results: Of the 930 eligible children, 44 (4.7%) aged 6–10 years were diagnosed with. The mean age at onset was 6.74 years. PFAS prevalence was 7.2% among children with allergic rhinitis (AR) and 19.1% among those with pollinosis, depending on comorbidity. PFAS was more prevalent in schoolchildren with atopic dermatitis, food allergy, and sensitization to food allergens and grass pollen in early childhood. In schoolchildren with AR, only a history of food allergy before 3 years increased the risk of PFAS (aOR 2.971, 95% CI: 1.159–7.615). Conclusion: Food allergy and food sensitization in early childhood was associated with PFAS in schoolchildren with AR. Further study is required to elucidate the mechanism by which food allergy in early childhood affects the development of PFAS.

Women in science: from images to data

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Catherine Jami
Keyword(s):  
Social Sciences ◽  
Gender Gap ◽  
Women Scientists ◽  
Working Environment ◽  
Women In Science ◽  
Standing Committee ◽  
Family Responsibilities ◽  
Working Lives ◽  
The Social ◽  
History Of

Abstract In recent decades research in the social sciences, including in the history of science, has shown that women scientists continue to be depicted as exceptions to the rule that a normal scientist is a man. The underlying message is that being an outstanding scientist is incompatible with being an ordinary woman. From women scientists’ reported experiences, we learn that family responsibilities as well as sexism in their working environment are two major hindrances to their careers. This experience is now backed by statistical analysis, so that what used to be regarded as an individual problem for each woman of science can now be identified as a multi-layered social phenomenon, to be analysed and remedied as such. Over the last five years, international scientific unions have come together to address these issues, first through the Gender Gap in Science Project, and recently through the setting up of a Standing Committee for Gender Equality in Science (SCGES) whose task is to foster measures to reduce the barriers that women scientists have to surmount in their working lives.

Type I Allergy to Egg and Milk Proteins: Comparison of Skin Prick Tests with Nasal, Buccal and Gastric Provocation Tests

1985 ◽  
Vol 77 (1-2) ◽  
pp. 171-173 ◽  
Author(s):  
P.L. Amlot ◽  
R. Urbanek ◽  
L.J.F. Youlten ◽  
M. Kemeny ◽  
M.H. Lessof
Keyword(s):  
Milk Proteins ◽  
Type I ◽  
Type I Allergy ◽  
Provocation Tests ◽  
Skin Prick Tests

scholarly journals Allergen-specific immunotherapy. Analytic review of current international and Russian federal position papers

2017 ◽  
Vol 14 (1) ◽  
pp. 24-32
Author(s):  
O M Kurbacheva ◽  
K S Pavlova ◽  
M A Galitzkaya
Keyword(s):  
Specific Immunotherapy ◽  
Allergic Diseases ◽  
Allergen Specific Immunotherapy ◽  
Detailed Understanding ◽  
Analytic Review ◽  
Ige Mediated ◽  
Federal Guidelines

The article analyses the international position papers devoted to allergen-specific immunotherapy published in recent years. It also describes in details Russian federal guidelines, published in the 2013-2016 years and dedicated to allergen-specific immunotherapy as a method of treatment of IgE-mediated allergic diseases, as well as Russian federal guidelines. Detailed understanding of indications, contraindications, and usage of AIT in various clinical situations are widely discussed.

scholarly journals Spirometry and mannitol bronchial challenge test among firefighters in Bhuj district: a questionnaire based study

2017 ◽  
Vol 4 (5) ◽  
pp. 1434
Author(s):  
Kashyap Buch ◽  
Vinayak Chauhan
Keyword(s):  
Nitric Oxide ◽  
Lung Disease ◽  
Chronic Lung Disease ◽  
Respiratory Symptoms ◽  
Challenge Test ◽  
Shortness Of Breath ◽  
Chest Tightness ◽  
Bronchial Challenge ◽  
Challenge Tests ◽  
Skin Prick Tests

Background: Asthma is a common chronic lung disease that inflames and narrows the airways. It causes recurring period of wheezing, chest tightness, shortness of breath and coughing.Methods: A questionnaire, spirometry, direct and indirect airway challenge tests, exhaled nitric oxide, and skin-prick tests were administered prospectively to 100 out of 120 firefighters employed in Bhuj district, Gujarat, India. Asthma was defined as the combination of respiratory symptoms with airway hyper responsiveness.Results: Twenty out of 100 firefighters (12%) had physician-diagnosed asthma, which could be confirmed in 8 firefighters. In contrast, asthma was diagnosed in 28% (28 of 100 firefighters). Wheezing was the most sensitive symptom for the diagnosis of asthma (sensitivity, 88%; specificity, 90%).Conclusions: Asthma was considerably under diagnosed in firefighters. The combination of a structured symptom questionnaire with a bronchial challenge test allows identifying patients with asthma and should routinely be used in the assessment of active firefighters and may be of help when evaluating candidates for this profession.

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