scholarly journals Effects of Countdown Signals in Red Phase on Drivers: A Comparative Study between Japan and Turkey

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Ke Yu ◽  
Huapu Lu

Countdown signals can be found in many countries; however, there are only a few researches that study the impact of the signals on driver behavior. In this study, we focus particularly on the behavior of drivers reacting to countdown signals when the signal shifted from red to green. Although the countdown signal can reduce startup delay, it also causes drivers premature start. This paper determines the factors influencing the behaviors of drivers on startup delay, premature start, and headway due to countdown signals. The analysis results are compared between Japan and Turkey. From our findings, we propose countermeasures to reduce the problems caused by the countdown signals which can be a guideline for implementation or modification of countdown-signalized intersections in many countries in order to increase safety of both drivers and pedestrians as well as drivers’ satisfactions.

2014 ◽  
Vol 222 (3) ◽  
pp. 140-147 ◽  
Author(s):  
Ariane Sölle ◽  
Theresa Bartholomäus ◽  
Margitta Worm ◽  
Regine Klinger

Research in recent years, especially in the analgesic field, has intensively studied the placebo effect and its mechanisms. It has been shown that physical complaints can be efficiently reduced via learning and cognitive processes (conditioning and expectancies). However, despite evidence demonstrating a large variety of physiological similarities between pain and itch, the possible transfer of the analgesic placebo model to itch has not yet been widely discussed in research. This review therefore aims at highlighting potential transfers of placebo mechanisms to itch processes by demonstrating the therapeutic issues in pharmacological treatments for pruritus on a physiological basis and by discussing the impact of psychological mechanisms and psychological factors influencing itch sensations.


2003 ◽  
Vol 18 (4) ◽  
pp. 388-394 ◽  
Author(s):  
Stefan Antonsson ◽  
Mikael E. Lindstrom ◽  
Martin Ragnar

Author(s):  
Samuel Azuz ◽  
Max Newton ◽  
Dorthe Bartels ◽  
Birgitte Klindt Poulsen

Abstract Purpose The aim of this study was to describe the implementation and uptake of biosimilar trastuzumab in Denmark compared with other European countries. Methods European data for usage of trastuzumab was supplied by IQVIA™, using the MIDAS® dataset. A comparison was performed based on market share estimated in sales volume. A separate comparison was undertaken between countries with a full two-fold switch between different biosimilars. Data was collected spanning the time from first registered sales of biosimilar trastuzumab until the 1st quarter of 2020. Results Denmark had the fastest and most thorough uptake of biosimilar trastuzumab compared with other EU countries. After 3 months, the market share of biosimilar trastuzumab had increased to 90% while the second fastest country had a 50% market share after 3 months. Only two other countries had undergone a full second switch between biosimilars, Hungary and Norway. All of the three countries made near complete switches between biosimilars while only Denmark had reduced the use of biooriginator below 10%. Conclusion The implementation of biosimilar trastuzumab in Denmark was rapid and achieved high overall uptake compared with other EU countries. The switch from one biosimilar to another was also achieved quickly and thoroughly. We believe that the rapid dissemination of information and involvement of all stakeholders — administrators, pharmacies, prescribers, nurses, and patients — constitute the backbone of the Danish success. A similar strategy is recommend for biosimilar implementation in other countries.


2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Jianghao Du ◽  
Zhanyun Zhu ◽  
Junchang Yang ◽  
Jia Wang ◽  
Xiaotong Jiang

AbstractIn this paper, a comparative study was conducted on the extraction effects of six agents for collagen-based mural painting binders. These agents were used to extract the residual proteins in the non-aged and thermal aged samples. The protein extraction efficiencies of different extracting agents were quantitatively determined by bicinchoninic acid (BCA) method, and then processed by multivariate analysis of variance (MANOVA). The impact of the extraction process on the protein structure was characterized by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE), ultraviolet absorption spectrum (UV) and circular dichroism (CD). The results showed that, for both non-aged and aged samples, the extraction efficiency of 2 M guanidine hydrochloride (GuHCl) was significantly higher than the other five agents, with less damage to the protein structure during the extraction process.


Author(s):  
Maximilian Axer ◽  
Sven Martens ◽  
Robert Schlicht ◽  
Sven Wagner

AbstractThe potential utilisation of natural regeneration of European beech (Fagus sylvatica L.) for forest conversion has received little attention to date. Ecological knowledge is necessary to understand and predict successful natural regeneration of beech. The objective of this study was to improve understanding of what drives the occurrence of beech regeneration and, once regeneration is present, what drives its density. In the study, we utilised a forest inventory dataset provided by Sachsenforst, the state forestry service of Saxony, Germany. The dataset was derived from 8725 permanent plots. Zero-altered negative binomial models (ZANB) with spatial random effects were used to analyse factors influencing occurrence and density simultaneously. The results provided by the spatial ZANB models revealed that the probability of the occurrence of beech regeneration is highly dependent on seed availability, i.e. dependent on source trees in close proximity to a plot. The probability of beech regeneration rises with the increasing diameter of a potential seed tree and decreases with increasing distance to the nearest potential seed source. The occurrence of regeneration is affected by overstorey composition and competition exerted by spruce regeneration. Where sites are affected by groundwater or temporary waterlogging, the impact on the occurrence of regeneration is negative. Although distance to the nearest potential seed source has an influence on occurrence, this variable exerts no influence on density. A high regeneration density arises in conjunction with a high beech basal area in the overstorey. Beech regeneration density, but not occurrence, is negatively affected by browsing intensity. These variables can be used to predict the occurrence and density of beech regeneration in space to a high level of precision. The established statistical tool can be used for decision-making when planning forest conversion using natural regeneration.


Sign in / Sign up

Export Citation Format

Share Document