scholarly journals Feasibility of Collecting Vulvar Pain Variability and Its Correlates Using Prospective Collection with Smartphones

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Ruby H. N. Nguyen ◽  
Rachael M. Turner ◽  
Jared Sieling ◽  
David A. Williams ◽  
James S. Hodges ◽  
...  

Context. Vulvar pain level may fluctuate in women with vulvodynia even in the absence of therapy; however, there is little evidence suggesting which factors may be associated with variability. Objective. Determine the feasibility of using smartphones to collect prospective data on vulvar pain and factors that may influence vulvar pain level. Methods. 24 clinically confirmed women were enrolled from a population-based study and asked to answer five questions using their smartphones each week for one month. Questions assessed vulvar pain level (0–10), presence of pain upon wakening, pain elsewhere in their body, treatment use, and intercourse. Results. Women completed 100% of their scheduled surveys, with acceptability measures highly endorsed. Vulvar pain ratings had a standard deviation within women of 1.6, with greater variation on average among those with higher average pain levels (P<0.001). On the weeks when a woman reported waking with pain, her vulvar pain level was higher by 1.82 on average (P<0.001). Overall, average vulvar pain level was not significantly associated with the frequency of reporting other body pains (P=0.64). Conclusion. Our smartphone tracking system promoted excellent compliance with weekly tracking of factors that are otherwise difficult to recall, some of which were highly associated with vulvar pain level.

Author(s):  
Jørgen Jeppesen ◽  
Tine W. Hansen ◽  
Michael H. Olsen ◽  
Susanne Rasmussen ◽  
Hans lbsen ◽  
...  

Background C-reactive protein (CRP), a marker of inflammation, and insulin resistance (IR), a metabolic disorder, are closely related. CRP and IR have both been identified as significant risk factors of cardiovascular disease (CVD) after adjustment for conventional CVD risk factors. It is not clear whether CRP predicts CVD independent of IR. Design Prospective population-based study. Methods Two thousand three hundred and fifty-seven Danish men and women, recruited from the general population, aged 41–72 years, without major CVD at baseline were studied. Traditional and new risk factors were recorded at baseline. CRP was determined by a high-sensitivity assay, and IR was determined by the homoeostasis model assessment (HOMA-IR) method. Results Over a median follow-up of 9.4 years, the incidence of the prespecified CV event, defined as the composite event of CV death, nonfatal ischaemic heart disease and nonfatal stroke, amounted to 222 cases. In Cox proportional-hazard models, adjusted for age, sex, smoking habit, total cholesterol, waist circumference, levels of triglycerides and high-density lipoprotein-cholesterol, systolic and diastolic blood pressures, physical activity and HOMA-IR, the hazard ratio (95% confidence interval) of a CV event was 1.33 (1.14–1.55; 0.001) per standard deviation increase in log-transformed CRP level. In the same model, the hazard ratio of a CV event was 1.11 (1.02–1.21; P < 0.05) per standard deviation increase in HOMA-IR level. Conclusion In a general Danish population free of major CVD at baseline, both CRP and IR were significantly related to risk of CVD.


Cephalalgia ◽  
2006 ◽  
Vol 26 (4) ◽  
pp. 436-444 ◽  
Author(s):  
LS Gudmundsson ◽  
G Thorgeirsson ◽  
N Sigfusson ◽  
H Sigvaldason ◽  
M Johannsson

Several studies have explored a possible association between migraine and hyper- tension, with contradictory results. Because of this uncertainty the relation between blood pressure (BP) and migraine was studied in 10 366 men and 11 171 women in a population-based longitudinal study. A modified version of the 1988 International Headache Society criteria was used for diagnosis of migraine. Logistic regression analysis was used. The crude 1-year prevalence of migraine was 5.2% among men and 14.1% among women. No significant association was found between hypertension and migraine. For a one standard deviation (SD) increase in diastolic BP the probability of having migraine increased 14% ( P = 0.11) for men and 30% ( P < 0.0001) for women. For a 1-SD increase in systolic BP the probability of having migraine decreased 19% ( P = 0.007) for men and 25% ( P < 0.0001) for women. It was also found that for a 1-SD increase in pulse pressure the probability of having migraine decreased 13% ( P = 0.005) for men and 14% ( P < 0.0001) for women. In a population-based study of men and women it was found that subjects with migraine had lower pulse pressure, lower systolic BP and higher diastolic BP compared with controls.


2001 ◽  
Vol 120 (5) ◽  
pp. A628-A628
Author(s):  
E LOFTUSJR ◽  
C CROWSON ◽  
W SANDBORN ◽  
W TREAMINE ◽  
W OFALLON ◽  
...  

2005 ◽  
Vol 173 (4S) ◽  
pp. 73-73 ◽  
Author(s):  
Daniel A. Barocas ◽  
Farhang Rabbani ◽  
Douglas S. Scherr ◽  
E. Darracott Vaughan

2005 ◽  
Vol 173 (4S) ◽  
pp. 401-401
Author(s):  
Javier Hernandez ◽  
Jacques Baillargeon ◽  
Brad Pollock ◽  
Alan R. Kristal ◽  
Patrick Bradshaw ◽  
...  

2000 ◽  
Vol 42 (5) ◽  
pp. 356-356
Author(s):  
Katarina Wide ◽  
Birger Winbladh ◽  
Torbjörn Tomson ◽  
Kerstin Sars-Zimmer ◽  
Eva Berggren

2003 ◽  
Vol 37 (3) ◽  
pp. 195-201 ◽  
Author(s):  
Per Larsson ◽  
Hans Wijkström ◽  
Andreas Thorstenson ◽  
Jan Adolfsson ◽  
Ulf Norming ◽  
...  

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