scholarly journals Angiomyolipoma of the Thoracic Wall: An Extremely Rare Diagnostic Challenge

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Georgios Gemenetzis ◽  
Eleni Kostidou ◽  
Kalliroi Goula ◽  
Vassilios Smyrniotis ◽  
Nikolaos Arkadopoulos
Keyword(s):  
Differential Diagnosis ◽  
Adipose Tissue ◽  
Smooth Muscle ◽  
Elastic Layer ◽  
Slow Rate ◽  
Benign Tumor ◽  
Thoracic Wall ◽  
Diagnostic Challenge ◽  
Postoperative Course ◽  
Mature Adipose Tissue

Extrarenal angiomyolipoma (AML) is an extremely uncommon lesion, accounting for less than 9% of all angiomyolipomas. We present a previously unreported case of a rarely located gigantic extrarenal angiomyolipoma at the posterolateral chest wall of a 35-year-old woman. Clinically, the lesion had all the characteristics of a benign tumor, being soft in palpation, painless, and growing in size in a slow rate. Histologically, the lesion consisted of convoluted thick-walled blood vessels without an elastic layer, interlacing fascicles of smooth muscle, and mature adipose tissue, features consistent with an angiomyolipoma. The mass was surgically removed, without any postoperative complications, and the patient has an uneventful postoperative course. Signs of local recurrence have not been observed. The purpose of this brief report is to point out the necessity of including angiomyolipoma in the differential diagnosis of adipose layer lesions.

scholarly journals Angiomyolipoma Originating From the Nasal Vestibule: A Case Report

2021 ◽  
pp. 014556132110362
Author(s):  
Aleksandar Perić ◽  
Jelena Sotirović ◽  
Miljan Folić ◽  
Biserka Vukomanović Đurdević
Keyword(s):  
Differential Diagnosis ◽  
Adipose Tissue ◽  
Smooth Muscle ◽  
Case Report ◽  
Microscopic Level ◽  
Rare Tumor ◽  
Nasal Vestibule ◽  
Mature Adipose Tissue ◽  
The Right ◽  
Gross Examination

Angiomyolipoma is a benign, mesenchymal, hamartomatous lesion often described in the kidney and may be associated with tuberous sclerosis. Nasal angiomyolipoma is an extremely rare tumor with fewer than 20 cases reported in the literature. We report a case of angiomyolipoma arising in the right nasal vestibule in a 68-year-old male with mild, recurrent right-sided epistaxis, and nasal obstruction. With the exception of arterial hypertension, the patient did not have any comorbidities. Gross examination showed a well-circumscribed, lobulated mass. On the microscopic level, it was composed of mature smooth muscle cells, thick-walled blood vessels of varying sizes, and islands of mature adipose tissue. Angiomyolipoma should be considered as a differential diagnosis for unilateral nasal masses, especially those situated in the nasal vestibule.

Primitive Neuroectodermal Tumor of Cerebrum With Adipose Tissue

2001 ◽  
Vol 125 (2) ◽  
pp. 264-266
Author(s):  
Satish Krishnamurthy ◽  
Stephen Kent Powers ◽  
Javad Towfighi
Keyword(s):  
Skeletal Muscle ◽  
Central Nervous System ◽  
Nervous System ◽  
Adipose Tissue ◽  
Smooth Muscle ◽  
Primitive Neuroectodermal Tumor ◽  
Primitive Neuroectodermal Tumors ◽  
Mature Adipose Tissue ◽  
Neuroectodermal Tumors ◽  
The Central Nervous System

Abstract Primitive neuroectodermal tumors (PNETs) of the central nervous system are uncommon embryonal neoplasms, rarely occurring in adults. Differentiation into specific mesenchymal tissues, such as cartilage, bone, skeletal muscle, smooth muscle, or adipose tissue, is rare. We report a case of a 51-year-old woman with a PNET of cerebrum that showed extensive mature adipose tissue differentiation. This is the second case, to our knowledge, of PNET of cerebrum with adipose tissue elements that has been described.

scholarly journals Myolipoma of Mesentery: A Case Report

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Hyun Sung Kim ◽  
Suk Kim ◽  
Kyungbin Kim ◽  
Kyung Un Choi ◽  
Joo Youn Kim
Keyword(s):  
Differential Diagnosis ◽  
Adipose Tissue ◽  
Soft Tissue ◽  
Clinical Course ◽  
Correct Diagnosis ◽  
Soft Tissue Tumors ◽  
Pelvic Cavity ◽  
Mature Adipose Tissue ◽  
Large Size ◽  
Deep Location

Myolipomas are very rare benign lipomatous soft tissue tumors which are usually located in retroperitoneum, abdominal and pelvic cavity, and the abdominal wall. They can be diagnosed histologically by the presence of irregularly admixed mature adipose tissue and smooth muscle fibers. The correct diagnosis of myolipoma is important, because it should be considered in the differential diagnosis of fat-containing lesions of the soft tissue and should follow a benign clinical course despite its frequently large size and deep location. We report here a case of myolipoma arising in the mesentery of the jejunum.

HMB45 and Melan-A Expression in Renal Angiomyolipoma and Their Significance for the Diagnosis

2003 ◽  
Vol 89 (1) ◽  
pp. 46-48 ◽  
Author(s):  
Emine Burçin Tuna ◽  
Banu Lebe ◽  
Kutsal Yörükoğlu
Keyword(s):  
Differential Diagnosis ◽  
Adipose Tissue ◽  
Smooth Muscle ◽  
Immunohistochemical Staining ◽  
Tumor Tissue ◽  
Mesenchymal Cells ◽  
Renal Angiomyolipoma ◽  
Immunoperoxidase Method ◽  
Tissue Block ◽  
Associated Proteins

Aims and Background The melanosome-associated proteins, also called HMB45 and melan-A, are also present in renal angiomyolipoma. The aim of the present study was to evaluate the expression of HMB45 and melan-A in mesenchymal cells of renal angiomyolipoma and to investigate their significance in the differential diagnosis. Methods Twelve patients, 9 females and 3 males diagnosed with renal angiomyolipomas, were included in the present study. The most representative tumor tissue block was chosen from each case, and 5-üm sections were taken to poly-l-lysin-coated slides for immunohistochemical staining. The standard streptavidin-biotin immunoperoxidase method was used for immunostaining with HMB45 and melan-A antibodies. Results All of the cases showed positive cytoplasmic immunostaining for HMB45 and melan-A. Melan-A expression was shown in smooth muscle component, adipose tissue and predominantly in the perivascular cells, whereas HMB45 immunoreactivity was stronger than melan-A expression in all cases. Conclusions It was concluded that HMB45 and melan-A reactivity is a useful tool to distinguish renal angiomyolipomas from other primary and secondary mesenchymal and primary epithelial tumors. Melan-A and HMB45 share similar specificities for renal angiomyolipoma. In addition, such expression in renal angiomyolipomas may occur without any evidence of nevomelanocytic differentiation. Further research is required to determine the histogenesis of this entity.

scholarly journals Uterine Angiomyolipoma: A Case Report, Differential Diagnosis with Pecoma and Review of the Literature

2014 ◽  
Vol 7 (1) ◽  
pp. 47-52 ◽  
Author(s):  
Tihomir P. Totev ◽  
Svetlana A. Mateva ◽  
Margarita R. Nikolova ◽  
Grigor A. Gorchev
Keyword(s):  
Differential Diagnosis ◽  
Adipose Tissue ◽  
Smooth Muscle ◽  
Case Report ◽  
Final Diagnosis ◽  
Morphological Aspect ◽  
Review Of The Literature ◽  
Immunohistochemical Examination ◽  
Mesenchymal Neoplasms ◽  
Vascular Component

Abstract Angiomyolipomas are benign mesenchymal neoplasms, presenting with a variable mixture of adipose tissue, smooth muscle and vascular component. Although they are typically found in the kidneys, many cases of extrarenal angiomyolipomas have been reported. They are extremely rarely present in the uterus. We describe a case of a 56-year-old woman, operated on for leiomyoma. Total laparohysterectomy and bilateral adnexectomy was performed. After histological and immunohistochemical examination, the final diagnosis of uterine angiomyolipoma was made. Renal and extrarenal angiomyolipomas are compared in regard to clinical and morphological aspect and their difference from PEComas is dicussed. PEComas have been defined during the last decade and there are still issues regarding terminological clarity and overlapping.

scholarly journals Uterine Angiolipoleiomyoma in a Dog

2001 ◽  
Vol 38 (6) ◽  
pp. 726-728 ◽  
Author(s):  
J. Boisclair ◽  
M. Doré
Keyword(s):  
Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Benign Tumor ◽  
Muscle Cells ◽  
Medium Size ◽  
Rare Tumor ◽  
Mature Adipose Tissue ◽  
S 100 ◽  
Small Clusters ◽  
Uterine Body

An 11-year-old crossbred Pomeranian bitch displayed a large intramural, well-delineated uterine mass in one horn, near the junction with the uterine body. The mass was composed largely of mature adipose tissue, smooth muscle cells singly and in small clusters, anomalous medium-size and large arteries, and multifocal islands of cartilaginous and osseous tissues. Smooth muscle cells stained positively for desmin, and adipocytes and chondrocytes were positive for S-100 protein. This tumor has histologic and immunohistochemical features compatible with human uterine angiolipoleiomyoma, a rare tumor that has never been reported in the veterinary literature. This benign tumor is believed to be of a choristomatous nature.

scholarly journals Angioleiomyoma of the Forearm

2014 ◽  
Vol 6 (01) ◽  
pp. 053-054 ◽  
Author(s):  
Biswajit Dey ◽  
Jyotsna Naresh Bharti ◽  
Parul Gautam ◽  
Seema Kaushal
Keyword(s):  
Differential Diagnosis ◽  
Smooth Muscle ◽  
Vascular Smooth Muscle ◽  
Benign Tumor ◽  
Immunohistochemical Examination ◽  
Nodular Mass ◽  
Painful Mass ◽  
The Right ◽  
Slow Growing ◽  
Growing Mass

ABSTRACTAngioleiomyoma is a benign tumor of vascular smooth muscle origin. Although many factors have been implicated in its pathogenesis, presence of lipometaplasia suggests its hamartomatous nature. This tumor presents as a painful nodular mass in extremities. Thus angioleiomyoma should be considered as a differential diagnosis of any solitary painful mass of forearm. Herein we report a case of 37-years-old female presenting with a slow growing mass in the right forearm. Histopathological and immunohistochemical examination confirmed the diagnosis of angioleiomyoma.

scholarly journals An incidental finding of uterine adenolipoleiomyoma in an endometrial polyp: A case report

2020 ◽  
Vol 7 (1) ◽  
pp. 19
Author(s):  
Edwin E Coello Gordon ◽  
Evelyn Carolina Polanco Jacome
Keyword(s):  
Adipose Tissue ◽  
Smooth Muscle ◽  
Case Report ◽  
Female Patient ◽  
Incidental Finding ◽  
Cervical Lesion ◽  
Endometrial Polyp ◽  
Mature Adipose Tissue

Uterine adenolipoleiomyoma is a benign hamartomatous lesion of controversial origin, with descriptions of exceptional cases published in the literature. We present the case of a 65-year-old female patient who presented an adenolipoleiomyoma in an endometrial polyp incidentally found during a hysterectomy performed for a cervical lesion. The incidental finding consisted of müllerian type glands, smooth muscle and mature adipose tissue.

Leiomyoma with Bizarre Nuclei (Symplastic Leiomyoma) in the Paratubal Cyst Wall: Report of a Rare Case

2021 ◽  
pp. 106689692199779
Author(s):  
Murat Celik
Keyword(s):  
Differential Diagnosis ◽  
Smooth Muscle ◽  
Cyst Wall ◽  
Rare Case ◽  
Clinical Behavior ◽  
Uterine Smooth Muscle ◽  
Smooth Muscle Neoplasm ◽  
Histological Variants ◽  
Eosinophilic Cytoplasm ◽  
Paratubal Cyst

Leiomyoma is a benign mesenchymal tumor that develops from smooth muscle cells. It can present in various histological variants. Leiomyoma with bizarre nuclei is an infrequent variant of uterine smooth muscle neoplasm. It is characterized by focally or diffusely distributed bizarre cells on the background of a typical leiomyoma. These bizarre cells are large, multinucleated, or multilobulated and have an eosinophilic cytoplasm. Even though leiomyomas with bizarre nuclei display benign clinical behavior, their differential diagnosis from leiomyosarcoma can sometimes be difficult. Leiomyoma has been described most commonly in the uterus. There is no case of leiomyoma originating from paratubal cysts described in the literature. In this article, we present a rare case of leiomyoma with bizarre nuclei originating from a paratubal cyst.

scholarly journals Large intraperitoneal lipoleiomyoma in a pre-menopausal woman: a case report

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Sara L. Schaefer ◽  
Amy L. Strong ◽  
Sheena Bahroloomi ◽  
Jichang Han ◽  
Michella K. Whisman ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Smooth Muscle ◽  
Case Report ◽  
Smooth Muscle Actin ◽  
Abdominal Mass ◽  
Histopathological Analysis ◽  
Menopausal Woman ◽  
En Bloc ◽  
Cross Sectional

Abstract Background Lipoleiomyoma is a rare, benign variant of the commonplace uterine leiomyoma. Unlike leiomyoma, these tumors are composed of smooth muscle cells admixed with mature adipose tissue. While rare, they are most frequently identified in the uterus, but even more infrequently have been described in extrauterine locations. Case presentation We describe a case report of a 45-year-old woman with a history of in vitro fertilization pregnancy presenting 6 years later with abdominal distention and weight loss found to have a 30-cm intra-abdominal lipoleiomyoma. While cross-sectional imaging can narrow the differential diagnosis, histopathological analysis with stains positive for smooth muscle actin, desmin, and estrogen receptor, but negative for HMB-45 confirms the diagnosis of lipoleiomyoma. The large encapsulated tumor was resected en bloc. The patients post-operative course was uneventful and her symptoms resolved. Conclusions Lipoleiomyoma should be considered on the differential diagnosis in a woman with a large intra-abdominal mass. While considered benign, resection should be considered if the mass is symptomatic, and the diagnosis is unclear or there is a concern for malignancy.

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