scholarly journals Comparison of Colour Duplex Ultrasound with Computed Tomography to Measure the Maximum Abdominal Aortic Aneurysmal Diameter

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
C. Gray ◽  
P. Goodman ◽  
S. A. Badger ◽  
M. K. O’Malley ◽  
M. K. O’Donohoe ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Duplex Ultrasound ◽  
Maximum Diameter ◽  
Excellent Correlation ◽  
Indication For Surgery ◽  
Limits Of Agreement ◽  
Main Indication ◽  
Abdominal Aortic ◽  
Small Aneurysms ◽  
Colour Duplex Ultrasound

Introduction. Maximum diameter of an abdominal aortic aneurysm (AAA) is the main indication for surgery. This study compared colour duplex ultrasound (CDU) and computed tomography (CT) in assessing AAA diameter.Patients and Methods. Patients were included if they had both scans performed within 90 days. Pearson’s correlation coefficient, pairedt-test, and limits of agreement (LOA) were calculated for the whole group. Subgroup analysis of small (<5.0 cm), medium (5.0–6.5 cm), and large (>6.5 cm) aneurysms was performed. APvalue of <0.05 was considered statistically significant.Results. 389 patients were included, giving 130 pairs of tests for comparison. Excellent correlation was in the whole group (r= 0.95) and in the subgroups (r= 0.94; 0.69; 0.96, resp.). Small LOA between the two imaging modalities was found in all subgroups.Conclusion. Small aneurysms can be accurately measured using CDU. CDU is preferable for small AAAs, but cannot supplant CT for planning aortic intervention.

Computed Tomography Versus Color Duplex Ultrasound for Surveillance of Abdominal Aortic Stent-Grafts

2005 ◽  
Vol 12 (5) ◽  
pp. 568-573 ◽  
Author(s):  
Ali F. AbuRahma ◽  
Christine A. Welch ◽  
Bandy B. Mullins ◽  
Benjamin Dyer
Keyword(s):  
Computed Tomography ◽  
Duplex Ultrasound ◽  
Stent Grafts ◽  
Abdominal Aortic ◽  
Versus Color ◽  
Color Duplex Ultrasound

scholarly journals Maximum Diameter of Native Abdominal Aortic Aneurysm Measured by Angio-Computed Tomography

Aorta ◽  
2015 ◽  
Vol 03 (02) ◽  
pp. 47-55 ◽  
Author(s):  
Caroline Mora ◽  
Claude Marcus ◽  
Coralie Barbe ◽  
Fiona Ecarnot ◽  
Anne Long
Keyword(s):  
Computed Tomography ◽  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Weighted Kappa ◽  
Maximum Diameter ◽  
Clinical Decisions ◽  
Diameter Measurement ◽  
Double Blind ◽  
Automated Method ◽  
Abdominal Aortic

Background: Computed tomography angiography (CTA) is the reference technique for the measurement of native maximum abdominal aortic aneurysm (AAA) diameter when surgery is being considered. However, there is a wide choice available for the methodology of maximum AAA diameter measurement on CTA, and to date, no consensus has been reached on which method is best. We analyzed clinical decisions based on these various measures of native maximum AAA diameter with CTA, then analyzed their reproducibility and identified the method of measurement yielding the highest agreement in terms of patient management. Materials and Methods: Three sets of measures in 46 native AAA were obtained, double-blind by three radiologists (J, S, V) on orthogonal planes, curved multiplanar reconstructions, and semi-automated-software, based on the AAA-lumen centerline. From each set, the clinical decision was recorded as follows: "Follow-up" (if all diameters <50 mm), "ambiguous" (if at least one diameter <50 mm AND at least one ≥50 mm) or "Surgery " (if all diameters ≥50 mm). Intra- and interobserver agreements in clinical decisions were compared using the weighted Kappa coefficient. Results: Clinical decisions varied according to the measurement sets used by each observer, and according to intra and interobserver (lecture#1) reproducibility. Based on the first reading of each observer, the number of AAA proposed for surgery ranged from 11 to 24 for J, 5 to 20 for S, and 15 to 23 for V. The rate of AAAs classified as "ambiguous" varied from 11% (5/46) to 37% (17/46).The semi-automated method yielded very good intraand interobserver agreements in clinical decisions in all comparisons (Kappa range 0.83–1.00). Conclusion: The semi-automated method seems to be appropriate for native AAA maximum diameter measurement on CTA. In the absence of AAA outer-wallbased software more robust for complex AAA, clinical decisions might best be made with diameter values obtained using this technique.

Effect of Thrombus in AAA on Pressure and Dilation Experienced by the Aneurysm Wall

2001 ◽  
Author(s):  
Mano J. Thubrikar ◽  
Francis Robicsek ◽  
Michel Labrosse ◽  
Vassil Chervenkoff ◽  
Brett L. Fowler
Keyword(s):  
Maximum Diameter ◽  
Pressure Measurements ◽  
Indication For Surgery ◽  
Intraluminal Thrombus ◽  
Aneurysm Wall ◽  
Abdominal Aortic ◽  
Before And After

Abstract Various factors are considered to play a role in the risk of abdominal aortic aneurysm (AAA) rupture. For instance, a maximum diameter of 7 cm is commonly used as an indication for surgery. There is a need for understanding what makes an aneurysm most likely to rupture. Our focus here is on the role of the intraluminal thrombus and how it affects the pressure and dilation experienced by the aneurysm wall. Since in most of the surgical procedures, the whole aneurysms are almost never removed, the data on the whole aneurysms with thrombus has not been available. The results presented here, therefore, are very important even though they come from a small number of whole aneurysms explored thoroughly. Two types of studies were performed: 1) in vitro and in vivo pressure measurements through the thrombus in three complete AAA, and 2) in vitro dilation measurements during pressurization of two whole aneurysms before and after the thrombus was removed.

3D Reconstruction of Patient-Specific Abdominal Aortic Aneurysms: From CT Scan to Silicone Model

2007 ◽  
Author(s):  
Barry J. Doyle ◽  
Liam G. Morris ◽  
Anthony Callanan ◽  
Eamon Kavanagh ◽  
Pat Kelly ◽  
...  
Keyword(s):  
Clinical Importance ◽  
Aortic Aneurysms ◽  
Maximum Diameter ◽  
Patient Specific ◽  
Abdominal Aortic ◽  
The Us ◽  
Normal Diameter ◽  
The Uk ◽  
Silicone Model ◽  
Small Aneurysms

Abdominal aortic aneurysm (AAA) is a local, permanent, irreversible dilation of the infrarenal section of the aorta that risks rupture until treated. AAA is defined as an infrarenal diameter 1.5 times the normal diameter. Currently, surgeons intervene when the aneurysm reaches a maximum diameter of 50mm [1]. 200,000 new cases are diagnosed each year in the US, with 500,000 new cases diagnosed worldwide [2]. This results in 15,000 deaths each year from AAA rupture in the US alone [3], with 8,000 deaths per year in the UK [4]. Literature supports the theory that small aneurysms may be as likely to rupture as larger aneurysms [5–7], and therefore, the need for a more reliable predictor of AAA rupture may have clinical importance.

Abstract 15839: Patients With Abdominal Aortic Aneurysms Have Reduced Levels of MicroRNA 122-5p in Circulating Exosomes

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Jose L Lopez ◽  
Joel L Ramirez ◽  
Tuan Anh Phu ◽  
Phat Duong ◽  
Laura Bouchareychas ◽  
...  
Keyword(s):  
Mirna Expression ◽  
Expression Profiles ◽  
Duplex Ultrasound ◽  
Abdominal Aortic Aneurysms ◽  
The United States ◽  
Mirna Expression Profile ◽  
Aortic Aneurysms ◽  
Aortic Diameter ◽  
Maximum Diameter ◽  
Abdominal Aortic

Introduction: There are currently no specific biomarkers to screen and monitor disease progression in abdominal aortic aneurysms (AAA), which are the 15 th leading cause of death in the United States. Circulating exosomes contain microRNAs (miRNA) that are potential biomarkers of disease. This study aimed to characterize the exosomal miRNA expression profile of patients with AAA in order to identify novel markers of disease. Methods: A total of 109 patients scheduled to undergo a duplex ultrasound (US) for screening or surveillance of AAA were screened to participate in the study. Eleven patients with AAA (max aortic diameter >3cm) and 15 non-aneurysmal controls (max aortic diameter <3cm on screening US) were enrolled. Circulating plasma exosomes were isolated using Cushioned-Density Gradient Ultracentrifugation and total RNA was extracted. Next Generation Sequencing was performed on the Illumina HiSeq4000 SE50 after NEBNext Multiplex Small RNA Library Prep. Differential miRNA expression analysis was performed using DESeq2 software with a Benjamini-Hochberg correction. MicroRNA expression profiles were validated by Quantitative Real-Time PCR. Results: Aortic diameter, as measured by US, was significantly larger in the AAA group (mean maximum diameter 5.2 vs 2.3 cm, p =2.84x10 -6 ). Aneurysm patients were more likely to suffer from CAD (5/11 vs 1/15, p = 0.05) but had similar levels of PAD (4/11 vs 2/15, p =0.35) and COPD (4/11 vs 4/15, p =0.68) compared to controls. A total of 40 miRNAs were differentially expressed ( p <0.05). Of these, 18 miRNAs were up-regulated and 22 were down-regulated in controls compared to AAA. After false discovery rate (FDR) adjustment, only miR-122-5p was expressed at significantly different levels in AAA compared to controls (fold change = 5.03 controls vs AAA; raw p = 1.8x10 -5 ; FDR p =0.02). Conclusions: Plasma exosomes from AAA patients have significantly reduced levels of miRNA-122-5p compared to controls.

scholarly journals Duplex ultrasound and computed tomography angiography in the follow-up of endovascular abdominal aortic aneurysm repair: a comparative study

2016 ◽  
Vol 49 (4) ◽  
pp. 229-233 ◽  
Author(s):  
Alex Aparecido Cantador ◽  
Daniel Emílio Dalledone Siqueira ◽  
Octavio Barcellos Jacobsen ◽  
Jamal Baracat ◽  
Ines Minniti Rodrigues Pereira ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Ct Angiography ◽  
Duplex Ultrasound ◽  
Abdominal Aortic Aneurysm Repair ◽  
Abdominal Aortic ◽  
Aneurysm Repair ◽  
Aortic Aneurysm Repair

Abstract Objective: To compare duplex ultrasound and computed tomography (CT) angiography in terms of their performance in detecting endoleaks, as well as in determining the diameter of the aneurysm sac, in the postoperative follow-up of endovascular abdominal aortic aneurysm repair. Materials and Methods: This was a prospective study involving 30 patients who had undergone endovascular repair of infrarenal aortoiliac aneurysms. Duplex ultrasound and CT angiography were performed simultaneously by independent radiologists. Measurements of the aneurysm sac diameter were assessed, and the presence or absence of endoleaks was determined. Results: The average diameter of the aneurysm sac, as determined by duplex ultrasound and CT angiography was 6.09 ± 1.95 and 6.27 ± 2.16 cm, respectively. Pearson's correlation coefficient showing a statistically significant correlation (R = 0.88; p < 0.01). Comparing the duplex ultrasound and CT angiography results regarding the detection of endoleaks, we found that the former had a negative predictive value of 92.59% and a specificity of 96.15%. Conclusion: Our results show that there is little variation between the two methods evaluated, and that the choice between the two would have no significant effect on clinical management. Duplex ultrasound could replace CT angiography in the postoperative follow-up of endovascular aneurysm repair of the infrarenal aorta, because it is a low-cost procedure without the potential clinical complications related to the use of iodinated contrast and exposure to radiation.

scholarly journals Prognostication of the abdominal aortic aneurysm with a novel three-dimensional ultrasonographic analysis system and its comparison with computed tomography

2021 ◽  
Vol 22 (Supplement_1) ◽  
Author(s):  
S Younus ◽  
H Maqsood ◽  
R Awais ◽  
A Gulraiz ◽  
MD Khan
Keyword(s):  
Computed Tomography ◽  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Three Dimensional ◽  
Maximum Diameter ◽  
Two Dimensional ◽  
Vessel Lumen ◽  
Abdominal Aortic ◽  
Risk Of Rupture ◽  
Analysis System

Abstract Funding Acknowledgements Type of funding sources: Other. Main funding source(s): Self Introduction An abdominal aortic aneurysm is a life-threatening condition and the risk of rupture is higher with the increased maximum diameter (Dmax) and expansion rate. Therefore, AAAs require regular monitoring of Dmax. The most commonly used imaging technique for measuring AAA size is two-dimensional ultrasonography (2-D US), closely followed by computed tomography (CT). Purpose : This study sought to evaluate the accuracy of a novel semi-automated 3-D ultrasonography (3-D US) system and its comparison CT as a reference. Methods : A total of 66 patients with abdominal aortic aneurysm were prospectively recruited in an outpatient setting. Two-dimensional ultrasonography (2-D US) and 3-D US images were attained with a single-sweep volumetric transducer. Dmax and the vessel area of the Dmax slice were measured with 2-D US, 3-D US, and CT. The vessel, lumen, and thrombus areas of the Dmax slice were also measured using 3-D US and CT. Results : It was found that the Dmax values from the 3-D US demonstrate better agreement (R2 = 0.971) with the CT values than with the 2-D US values (R2 = 0.929). Overall, 2-D US underestimated Dmax compared with 3-D US (30.8 ± 13.1mm vs. 34.4 ± 11.6 mm). The vessel, lumen, and thrombus areas all demonstrated better agreement with CT than with 2-D US (R2 = 0.988 vs. 0.961 for the vessel, R2 = 0.879 vs. 0.829 for the lumen, and R2 = 0.963 vs. 0.849 for the thrombus). Conclusion : Our study concludes that our novel semi-automated 3-D US analysis system provides more accurate Dmax values and volumetric data as compared to the 2-D US. The application of the semi-automated 3-D US analysis system in an abdominal aorta assessment is easy and accurate. Abstract Figure. Comparison of AAA on three modalities

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