scholarly journals Body Composition and Basal Metabolic Rate in Women with Type 2 Diabetes Mellitus

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Marina de Figueiredo Ferreira ◽  
Filipe Detrano ◽  
Gabriela Morgado de Oliveira Coelho ◽  
Maria Elisa Barros ◽  
Regina Serrão Lanzillotti ◽  
...  

Objective.The aim of this study was to determine which of the seven selected equations used to predict basal metabolic rate most accurately estimated the measured basal metabolic rate.Methods.Twenty-eight adult women with type 2 diabetes mellitus participated in this cross-sectional study. Anthropometric and biochemical variables were measured as well as body composition (by absorptiometry dual X-ray emission) and basal metabolic rate (by indirect calorimetry); basal metabolic rate was also estimated by prediction equations.Results.There was a significant difference between the measured and the estimated basal metabolic rate determined by the FAO/WHO/UNU(Pvalue<0.021)and Huang et al.(Pvalue≤0.005)equations.Conclusion.The calculations using Owen et al’s. equation were the closest to the measured basal metabolic rate.

2016 ◽  
Vol 39 (6) ◽  
pp. 2439-2450 ◽  
Author(s):  
Sheyu Li ◽  
Jia Wei ◽  
Chenghui Zhang ◽  
Xiaodan Li ◽  
Wentong Meng ◽  
...  

Background/Aims: The aim of this study was to assess the association between circulating cell-derived microparticles (MPs) and type 2 diabetes mellitus (T2DM). Methods: A literature search was performed systematically in PubMed and Embase to identify available case-control or cross-sectional studies that compared different types of cell-derived MPs in patients with T2DM and non-diabetic controls. Pooled standardized mean differences (SMDs) of each MP type were pooled using meta-analysis. Results: Forty-eight studies involving 2,460 patients with T2DM and 1,880 non-diabetic controls were included for systematic review and 34 of which were included for quantitative study by meta-analysis. In the overall analysis, the levels of circulating total MPs (TMPs), platelet-derived MPs (PMPs), monocyte-derived MPs (MMPs) and endothelium-derived MPs (EMPs) were significantly higher in T2DM patients than those in controls (TMPs: SMD, 0.64; 95%CI, 0.12∼1.15; P=0.02; PMPs: SMD, 1.19; 95%CI, 0.88∼1.50; P <0.00001; MMPs: SMD, 0.92; 95%CI, 0.66∼1.17; P <0.00001; EMPs: SMD, 0.73; 95%CI, 0.50∼0.96; P <0.00001). Meanwhile, no significant difference was shown in leukocyte-derived MPs (LMPs) level between diabetic and non-diabetic groups (SMD, 0.37; 95%CI, -0.15∼0.89; P=0.17). Conclusions: The counts of TMPs, PMPs, MMPs and EMPs elevated in patients with T2DM. And cell-derived MPs may play a role in the pathogenesis of T2DM.


2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Masoud Mohebbi ◽  
Katayoun Samadi ◽  
Nazafarin Navari ◽  
Melika Ziafati-fahmideh-sani ◽  
Golshid Nourihosseini ◽  
...  

Background: Diabetic nephropathy occurs in 20 - 30% of diabetic cases globally, and microalbuminuria (MA) is the first symptom of this disorder. Some studies have suggested that there is an association between the serum magnesium (Mg) level and MA. Objectives: Therefore, we investigated the association between the serum Mg level and MA in type 2 diabetes mellitus (T2DM) patients. Methods: We conducted a cross-sectional study on 122 subjects with T2DM. We categorized them into two groups of microalbuminuria (MA) and non-microalbuminuria (NMA) according to their urine albumin-creatinine ratio (UACR). MA was considered as a UACR of 30 to 300 mg/g. Participants were excluded if they had the following conditions: The age of under 16 years, cardiac, renal, or hepatic disorders, using corticosteroids, diuretics, Mg /calcium (Ca) supplements, and antiepileptic drugs, heavy physical activity within 24 hours before the test, pregnant and breastfeeding women, febrile patients, and patients who were unwilling to participate in the study. The analysis was performed using SPSS version 15. A P-value < 0.05 was considered significant. Results: Among the patients, 50.81% were male. Also, the mean body mass index (BMI) of the NMA group was greater than the MA group (29.84 ± 5.64 vs. 27.31 ± 3.14, P-value = 0.003). Mg levels of the MA and NMA groups showed no significant differences (2.13 ± 0.42 and 2.10 ± 0.43, respectively; P-value = 0.67). Overall, data analysis provided no significant difference between Mg level and the urine albumin concentration between the MA and NMA groups (P-value = 0.21 and 0.81, respectively.). Conclusions: Serum Mg level and MA have no significant relationship. Further prospective studies are needed to assay this issue.


Jurnal BIOMA ◽  
2015 ◽  
Vol 11 (1) ◽  
pp. 1
Author(s):  
HENI KRISTINA ◽  
NURMASARI SARTONO ◽  
RUSDI RUSDI

ABSTRACT Prevalence of type 2 diabetes mellitus rapidly increase in industry and developing country. Oxidative stress was estimated has role in development of type 2 diabetes mellitus. This study was aim to measure levels of malondialdehyde (MDA) and activity of superoxide dismutase (SOD) in type 2 diabetes mellitus, and also to analyse the relationship among both. This study was conducted on July-October 2014, using Ex Post Facto method and cross sectional design. The result showed that MDA serum levels significantly higher in diabetes mellitus patient compare to normal (P=0,000). Activity of superoxide dismutase (SOD) in diabetes mellitus serum has no significant difference with normal (P=0,290).There was possitive correlation between levels of MDA and activity of SOD in type 2 diabetes mellitus but not significant (P=0,478) with rs=0,199, thus also in normal subject (P=0,194) with rs=0,355. There was no significant different between two correlation  coefficient  (P=0,6781).  In  conclusion,  there was significant different level of MDA, there was no significant different activity of SOD, there was positive correlation but not significant between levels of MDA and activity of SOD serum in type 2 diabetes mellitus and normal. And there was no significant different between two correlation coefficient.   Keywords: malondialdehyde, superoxide dismutase, type 2 diabetes mellitus


Author(s):  
Vipin Kumar ◽  
Maya Pensiya ◽  
V B Singh

Background: To study the lipid profile in diabetes mellitus in type 2 Diabetes mellitus patients. Methods: This is a cross sectional case control study. 100 patients of type 2 diabetes mellitus and 100 age and sex matched healthy controls were taken. Lipid profile were done in cases and controls using appropriate tests. Results: The fasting blood sugar levels in all the diabetics were significantly higher as compare to control. There was significant difference in mean HDL, Triglycerides level in diabetic and control patients. There was no significant difference in LDL, Cholesterol level in Diabetic and control patients. Conclusion: We concluded that there is a high prevalence of elevated lipid levels among the diabetic patients. Keywords: Diabetes Mellitus -2, Cholesterol, Lipid Profile


2021 ◽  
Vol 71 (Suppl-1) ◽  
pp. S123-29
Author(s):  
Zara Khalid Khan ◽  
Muhammad Uzair Khan ◽  
Amna Khalid Khan ◽  
Rukhsana Muttee ◽  
Rubeena Khalid ◽  
...  

Objective: To determine the development of dyslipidemia in type 2 diabetics with and without periodontaldiseases. Study Design: Comparative cross-sectional study. Place and Duration of Study: Fauji Foundation Hospital and Pak Emirates Military Hospital, Rawalpindi,Pakistan, from Jan 2018 to Jan 2019. Methodology: Total number of participated subjects (males and females) was 75, with age ranging from 23 to 72 years. Their tests included blood sugar, lipid profile, HbA1c and hepatitis screening. Oral health parameters were divided into two categories; type 2 diabetes mellitus with and without periodontitis. Results: Out of 75 patients, males and females were 19 (25.3%) and 56 (74.7%). Females with periodontitis 20(74.1%) and without periodontitis 36 (75%) possessed larger numbers. Mean ages [56.33 ± 10.88 years] hada higher incline, along with significantly altered total cholesterol [5.41 ± 1.70 mmol/l], triglycerides [2.55 ± 1.46mmol/l], low and high density lipoproteins [3.01 ± 1.22 mmol/l, 0.97 ± 0.48 mmol/l] in type 2 diabetes mellituswith periodontitis. Patients of diabetes without periodontitis showed mild derangements for triglycerides [1.88 ± 1.22 mmol/l]. Patients of diabetes with dyslipidemia and periodontitis 16 (59.3%) were documented highest innumber, compared to other type 2 diabetes mellitus groups. Conclusion: There was an overall significant association between type 2 diabetes mellitus related dyslipidemiaand periodontitis. Also, significant difference in age and gender of study subjects was noted that affected middle aged females more often than middle to late aged males.


Author(s):  
Phan Ai Ping ◽  
Rosnani Zakaria ◽  
Md Asiful Islam ◽  
Lili Husniati Yaacob ◽  
Rosediani Muhamad ◽  
...  

Type 2 diabetes mellitus (T2DM) and tuberculosis (TB) together impose a high disease burden in terms of both mortality and health economics worldwide. The objective of this study was to estimate the prevalence and risk factors of latent TB infection (LTBI) in patients with T2DM in Malaysia. A cross-sectional study was performed, and adult T2DM patients (n = 299) were included. Simple and multiple logistic regression analyses were performed to identify the LTBI-associated risk factors in patients with T2DM. Multiple logistic regression was used to estimate adjusted odds ratios (aOR) and 95% confidence intervals (CIs) between T2DM and LTBI and was adjusted for potential confounders. The prevalence of LTBI in patients with T2DM was 11.4% (95% CI: 8.0–15.0%). There was no significant difference in the socio-demographic characteristics between LTBI and non-LTBI subjects. No significant difference in the smoking status, the duration of smoking, and the duration of T2DM, HbA1c, or treatments was observed. Interestingly, a higher level of education was observed to be associated with a lower prevalence of LTBI in T2DM patients (aOR: 0.08, 95% CI: 0.01–0.70, p = 0.02). Although the prevalence of LTBI in T2DM was low, it is important to screen for it in T2DM patients due to the risk of developing severe active TB.


2015 ◽  
Vol 2 (2) ◽  
pp. 34-38 ◽  
Author(s):  
Roksana Yeasmin ◽  
Nazmun Nahar ◽  
MA Muttalib ◽  
Md. Nizamul Hoque Bhuiyan ◽  
ATM Zoadur Rahim Zahid ◽  
...  

Background: The pattern of dyslipidemia varies among the patients of type 2 of diabetes mellitus. Objective: The purpose of the present study was to observe gender difference of lipid abnormalities in type-2 Diabetes Mellitus patients.Methodology: This cross sectional comparative study was conducted in the OPD of Department of medicine at BIRDEM, Dhaka from January, 2014 to July, 2014 for a period of six months. Convenient purposive sampling method was used and data assessed in a prospective manner. Blood sugar (FBS, ABF), lipid profile (TG, TC, LDLC, and HDLC) were measured. Statistical analyses were performed with the SPSS software program.Results: A total number of 400 type 2 DM patients (200 males and 200 females) attending to BIRDEM OPD were recruited in this study. Blood sugar was higher than normal in both male and female (FBS=8.79±.20, 8.64±0.22 respectively and ABF=12.15±0.27, 11.8±0.29 mmol/l respectively). TG level was also higher in two groups of study subjects with male level is slightly more than female (194.99±6.72 and 185.21±15.51 respectively) with no significant difference between the groups (P>.05). Total cholesterol and LDL-C level was within normal physiological level in both groups, where as these levels were higher in female in comparison to male (TC=184.44±3.33 &166.16±3.04 respectively, LDLC=109.68±2.59 & 88.66±2.59 respectively), showing significant difference between the groups (P=.000). HDL-C was below normal in both male (38.28± 48) and female (39.02±2.59); however HDL-C was slightly higher in female than male and the difference was insignificant (p=.330). Conclusion: In conclusion dyslipidemia were observed in a greater proportion of female diabetic patients than male diabetic patients.Journal of Current and Advance Medical Research, 2015;2(2):34-38


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