scholarly journals Atorvastatin Combining with Probucol: A New Way to Reduce Serum Uric Acid Level during Perioperative Period of Interventional Procedure

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Hong Li ◽  
Ximing Li ◽  
Hongjun Ma ◽  
Yiran Wang ◽  
Naikuan Fu ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Interventional Procedure ◽  
Serum Uric Acid Level ◽  
Kidney Injury ◽  
Perioperative Period ◽  
Group I

Uric acid has ever been considered as one of contrast induced acute kidney injury’s risk factors. Atorvastatin and probucol can both improve contrast induced acute kidney injury separately. This prospective study is to assess their effect on reducing serum uric acid level and contrast induced acute kidney injury during perioperative period of interventional procedure. On the basis of different doses of atorvastatin and probucol, 208 cases admitted for coronary angiography or percutaneous coronary intervention were randomly classified into standard combined group (S-C group), intensive combined group (I-C group), and intensive atorvastatin group (I-A group). Patients’ blood urea nitrogen, serum creatinine, and serum uric acid were measured and estimated glomerular filtration rate was evaluated 24 hours before and after the procedure. After procedure, blood urea nitrogen in all the three groups decreased; Scr of S-C group and I-A group increased significantly, while estimated glomerular filtration decreased in the S-C group (P<0.05); serum uric acid in S-C group and I-C group decreased significantly (P<0.05). Combination treatment of atorvastatin and probucol before intervention could reduce perioperative serum uric acid level; meanwhile, the intensive combined treatment can improve the contrast induced acute kidney injury. The result was the same for hypertensive patients.

scholarly journals Association of Hyperuricaemia with Perinatal Outcome in Pregnancy Induced Hypertension

2015 ◽  
Vol 32 (3) ◽  
pp. 124-129
Author(s):  
Saida Akter ◽  
Sharmin Sultana ◽  
Seema Rani Dabee
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Perinatal Outcome ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Pregnancy Induced Hypertension ◽  
Group I ◽  
Induced Hypertension ◽  
Group Ii

The high serum uric acid concentration correlates with the degree of severity of the pregnancy induced hypertension (PIH) and perinatal outcome. In this context, maternal serum uric acid level is reported to be one of the prognostic factor for determination of perinatal outcome. Based on the existing data, the present prospective study was undertaken in the Department of Obstetrics and Gynaecology, BIRDEM Academy, from January to December, 2010. Out of 120 women, 60 suffering from PIH (severe preeclampsia and eclampsia) served as group I and 60 normotensive women at third trimester of pregnancy served as group II. This study showed that mean (±SD) serum uric acid was significantly elevated in group I PIH patients (7.21±1.81 mg/dl) compared to group II normotensive pregnancy (4.40±0.84 mg/dl). In group I PIH patients, 39 (86%) had adverse perinatal outcome (preterm, IUGR, stillbirth), and 6 (13.3%) term and healthy deliveries when serum uric acid level was >6 mg/dl. Current study showed that there was positive and statistically significant relationship between diastolic blood pressure and hyperuricaemia in group I PIH patients (r = +0.359, P<0.01). This study also showed that in group I PIH patients, when serum uric acid increased, birth weight significantly decreased (r = 0.279, P<0.05).J Bangladesh Coll Phys Surg 2014; 32: 124-129

A STUDY OF SERUM URIC ACID LEVELS IN PREECLAMPSIA

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Sushma Goad ◽  
Anita Verma ◽  
Subhash Chandra
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Control Group ◽  
Age Group ◽  
Hypertensive Disorders Of Pregnancy ◽  
Level Elevation ◽  
The Mean

Background: To Study Serum Uric Acid level elevation in Hypertensive Disorders of Pregnancy. Methods: 50 Patients diagnosed as having Pre-eclampsia with age between 18-37 years and 50 controls with similar age group. Results: The mean serum uric acid level in control group was 3.41 ± 0.62 and in patient 7.01 ± 0.58 which was statistically significant (p =0.001). Conclusion: Serum uric acid levels were significantly higher in preeclampsia could be a useful indicator of fetal complication in preeclampsia patients. Keywords: serum uric acid, preeclampsia, laboratory.

scholarly journals Synergic effect in the reduction of serum uric acid level between ethanol extract of Aster glehni and vitamin B6

2018 ◽  
Vol 27 (5) ◽  
pp. 1439-1444 ◽  
Author(s):  
Eun Hye Han ◽  
Mi Kyung Lim ◽  
Sang Ho Lee ◽  
Hyoung Ja Kim ◽  
Dahyun Hwang
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Vitamin B6 ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Ethanol Extract ◽  
Synergic Effect

scholarly journals Lung function decline is associated with serum uric acid in Korean health screening individuals

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kyung-Min Ahn ◽  
Suh-Young Lee ◽  
So-Hee Lee ◽  
Sun-Sin Kim ◽  
Heung-Woo Park
Keyword(s):  
Uric Acid ◽  
Lung Function ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Forced Expiratory Volume ◽  
Linear Regression Models ◽  
Lung Function Decline ◽  
Health Screenings

AbstractWe performed a retrospective cohort study of 19,237 individuals who underwent at least three health screenings with follow-up periods of over 5 years to find a routinely checked serum marker that predicts lung function decline. Using linear regression models to analyze associations between the rate of decline in the forced expiratory volume in 1 s (FEV1) and the level of 10 serum markers (calcium, phosphorus, uric acid, total cholesterol, total protein, total bilirubin, alkaline phosphatase, aspartate aminotransferase, creatinine, and C-reactive protein) measured at two different times (at the first and third health screenings), we found that an increased uric acid level was significantly associated with an accelerated FEV1 decline (P = 0.0014 and P = 0.037, respectively) and reduced FEV1 predicted % (P = 0.0074 and P = 8.64 × 10–7, respectively) at both visits only in non-smoking individuals. In addition, we confirmed that accelerated forced vital capacity (FVC) and FEV1/FVC ratio declines were observed in non-smoking individuals with increased serum uric acid levels using linear mixed models. The serum uric acid level thus potentially predicts an acceleration in lung function decline in a non-smoking general population.

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