scholarly journals Carbon Nanotubes Reinforced Composites for Biomedical Applications

2014 ◽  
Vol 2014 ◽  
pp. 1-14 ◽  
Author(s):  
Wei Wang ◽  
Yuhe Zhu ◽  
Susan Liao ◽  
Jiajia Li

This review paper reported carbon nanotubes reinforced composites for biomedical applications. Several studies have found enhancement in the mechanical properties of CNTs-based reinforced composites by the addition of CNTs. CNTs reinforced composites have been intensively investigated for many aspects of life, especially being made for biomedical applications. The review introduced fabrication of CNTs reinforced composites (CNTs reinforced metal matrix composites, CNTs reinforced polymer matrix composites, and CNTs reinforced ceramic matrix composites), their mechanical properties, cell experimentsin vitro, and biocompatibility testsin vivo.

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Erfan Dashtimoghadam ◽  
Farahnaz Fahimipour ◽  
Andrew N. Keith ◽  
Foad Vashahi ◽  
Pavel Popryadukhin ◽  
...  

AbstractCurrent materials used in biomedical devices do not match tissue’s mechanical properties and leach various chemicals into the body. These deficiencies pose significant health risks that are further exacerbated by invasive implantation procedures. Herein, we leverage the brush-like polymer architecture to design and administer minimally invasive injectable elastomers that cure in vivo into leachable-free implants with mechanical properties matching the surrounding tissue. This strategy allows tuning curing time from minutes to hours, which empowers a broad range of biomedical applications from rapid wound sealing to time-intensive reconstructive surgery. These injectable elastomers support in vitro cell proliferation, while also demonstrating in vivo implant integrity with a mild inflammatory response and minimal fibrotic encapsulation.


2020 ◽  
Author(s):  
Erfan Dashtimoghadam ◽  
Farahnaz Fahimipour ◽  
Andrew Keith ◽  
Foad Vashahi ◽  
Pavel Popryadukhin ◽  
...  

Abstract Current materials used in biomedical devices do not match tissue’s mechanical properties and leach various chemicals into the body. These deficiencies pose significant health risks that are further exacerbated by invasive implantation procedures. Herein, we leverage the brush-like polymer architecture to design and administer minimally invasive injectable elastomers that cure in vivo into leachable-free implants with mechanical properties matching the surrounding tissue. This strategy allows tuning curing time from minutes to hours, which empowers a broad range of biomedical applications from rapid wound sealing to time-intensive reconstructive surgery. These injectable elastomers support in vitro cell proliferation, while also demonstrating in vivo implant integrity with a mild inflammatory response and minimal fibrotic encapsulation.


1988 ◽  
Vol 120 ◽  
Author(s):  
Karl M. Prewo

During the past 25 years materials scientists have been able to make a major change in the way materials are considered for application. In the past designers have worked with data representing the properties of homogeneous, isotropic materials and designed their components to fit written accepted ranges of “design allowables”. More recently, however, the concept of composite materials has permitted almost limitless tailoring of composites to create entirely new designs never previously possible. By choice of types of material constituents, their relative percentages and their orientation the designer can now work closely with the materials scientist to optimize system performance. This philosophy has firmly taken hold in the family of fiber reinforced polymer matrix composites and more recently has made metal matrix composites an industrial reality.


2012 ◽  
Vol 1 (1) ◽  
pp. 17-29 ◽  
Author(s):  
Giuseppe Lamanna ◽  
Alessia Battigelli ◽  
Cécilia Ménard-Moyon ◽  
Alberto Bianco

AbstractThe increasing importance of nanotechnology in the field of biomedical applications has encouraged the development of new nanomaterials endowed with multiple functions. Novel nanoscale drug delivery systems with diagnostic, imaging and therapeutic properties hold many promises for the treatment of different types of diseases, including cancer, infection and neurodegenerative syndromes. Functionalized carbon nanotubes (CNTs) are one of the most recent type of nanomaterial developed in biomedicine as they can be designed and imparted with multimodal capabilities. Indeed, the possibility of inserting different functionalities on CNTs is opening the possibility to exploit them on new strategies that combine diagnosis with improved therapeutic efficacies. In this review, we describe the different approaches that have been recently developed to generate multifunctionalized CNTs for biomedical applications. In particular, covalent and non-covalent double and triple functionalization methods are discussed, putting in evidence their use in vitro and in vivo and highlighting the advantages and the drawbacks of these new systems. Preclinical studies have demonstrated that multifunctional CNTs are highly promising when combining diagnostic, imaging and therapeutic modalities.


2009 ◽  
Vol 149 (39-40) ◽  
pp. 1693-1697 ◽  
Author(s):  
Urmimala Maitra ◽  
K. Eswar Prasad ◽  
U. Ramamurty ◽  
C.N.R. Rao

Author(s):  
Yves Ngabonziza ◽  
Hale Ergun ◽  
Regina Kuznetsova ◽  
Jackie Li ◽  
Benjamin Liaw ◽  
...  

Composite structural self-diagnostic (CSSD) technology has been tested to detect the mechanical damages in carbon-fiber reinforced polymer-matrix composites. In order to characterize the self-sensing technique for damage detection, discrete electrodes were mounted on Double-Cantilever-Beam (DCB). Results on mechanical properties with corresponding electrical resistance changes of the CFRC specimens are presented in this paper. The lay-up configuration of the composite specimens is [06/Teflon/06]T. In addition, acoustic emission was also used to corroborate the CSSD results.


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