scholarly journals Intraoperative Cerebral Glioma Characterization with Contrast Enhanced Ultrasound

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Francesco Prada ◽  
Luca Mattei ◽  
Massimiliano Del Bene ◽  
Luca Aiani ◽  
Marco Saini ◽  
...  
Keyword(s):  
Real Time ◽  
Flow Distribution ◽  
Distribution Patterns ◽  
Cerebral Glioma ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced ◽  
Venous Phase ◽  
First Time ◽  
Fast Perfusion

Background. Contrast enhanced ultrasound (CEUS) is a dynamic and continuous modality providing real-time view of vascularization and flow distribution patterns of different organs and tumors. Nevertheless its intraoperative use for brain tumors visualization has been performed few times, and a thorough characterization of cerebral glioma had never been performed before.Aim. To perform the first characterization of cerebral glioma using CEUS and to possibly achieve an intraoperative differentiation of different gliomas.Methods. We performed CEUS in an off-label setting in 69 patients undergoing surgery for cerebral glioma. An intraoperative qualitative analysis was performed comparing iCEUS with B-mode imaging. A postprocedural semiquantitative analysis was then performed for each case, according to EFSUMB criteria. Results were related to histopathology.Results. We observed different CE patterns: LGG show a mild, dotted CE with diffuse appearance and slower, delayed arterial and venous phase. HGG have a high CE with a more nodular, nonhomogeneous appearance and fast perfusion patterns.Conclusion. Our study characterizes for the first time human brain glioma with CEUS, providing further insight regarding these tumors’ biology. CEUS is a fast, safe, dynamic, real-time, and economic tool that might be helpful during surgery in differentiating malignant and benign gliomas and refining surgical strategy.

Application of real-time contrast-enhanced ultrasound in differential diagnosis of liver malignancies

2019 ◽  
Vol 97 (5) ◽  
pp. 341-344 ◽  
Author(s):  
Hongling Li ◽  
Jin Li
Keyword(s):  
Hepatocellular Carcinoma ◽  
Differential Diagnosis ◽  
Liver Cancer ◽  
Real Time ◽  
Contrast Enhanced Ultrasound ◽  
Portal Venous Phase ◽  
Contrast Enhanced ◽  
Different Types ◽  
Venous Phase ◽  
Malignant Liver

The objective of this study was to evaluate the value of real-time contrast-enhanced ultrasound in differential diagnosis of malignant liver tumors. Sixty patients pathologically diagnosed with liver cancer from May 2016 to May 2017 were selected as the subjects. All patients received ultrasonic diagnosis followed by the observation on dynamic contrast enhancement of the image and the analysis on perfusion characteristics and difference in contrast-enhanced ultrasound results in patients with different types of liver cancer. The signal during the arterial phase of 21 patients with well-differentiated hepatocellular carcinoma increased, including 12 cases of slow withdrawal of portal venous phase. The relative height of artery of 30 patients with middle-low differentiation of hepatocellular carcinoma increased along with the speed at which the contrast media was washed out at the end of the portal phase. In 9 patients with intrahepatic bile duct cancer, the enhancement of the arteries was slightly increased in the periphery of the tumor and low enhancement was found in the portal venous phase. There were some differences in the timing and the intensity of the enhancement of the ultrasound signals with 3 different types of diseases (P < 0.05). There are obvious differences in real-time contrast-enhanced ultrasound features of patients with different types of malignant liver tumor, which may provide references for clinical diagnosis.

Contrast-enhanced ultrasound of the abdominal aorta – current status and future perspectives

VASA ◽  
2019 ◽  
Vol 48 (2) ◽  
pp. 115-125 ◽  
Author(s):  
Xin Li ◽  
Daniel Staub ◽  
Vasileios Rafailidis ◽  
Mohammed Al-Natour ◽  
Sanjeeva Kalva ◽  
...  
Keyword(s):  
Real Time ◽  
Vascular Diseases ◽  
Aneurysm Rupture ◽  
Vasa Vasorum ◽  
Current Status ◽  
Contrast Enhanced Ultrasound ◽  
Aortic Diseases ◽  
Cross Sectional ◽  
Vascular Abnormalities ◽  
Contrast Enhanced

Abstract. Ultrasound has been established as an important diagnostic tool in assessing vascular abnormalities. Standard B-mode and Doppler techniques have inherent limitations with regards to detection of slow flow and small vasculature. Contrast-enhanced ultrasound (CEUS) is a complementary tool and is useful in assessing both the macro- and microvascular anatomy of the aorta. CEUS can also provide valuable physiological information in real-time scanning sessions due to the physical and safety profiles of the administered microbubbles. From a macrovascular perspective, CEUS has been used to characterize aortic aneurysm rupture, dissection and endoleaks post-EVAR repair. With regard to microvasculature CEUS enables imaging of adventitial vasa vasorum thereby assessing aortic inflammation processes, such as monitoring treatment response in chronic periaortitis. CEUS may have additional clinical utility since adventitial vasa vasorum has important implications in the pathogenesis of aortic diseases. In recent years, there have been an increasing number of studies comparing CEUS to cross-sectional imaging for aortic applications. For endoleak surveillance CEUS has been shown to be equal or in certain cases superior in comparison to CT angiography. The recent advancement of CEUS software along with the ongoing development of drug-eluting contrast microbubbles has allowed improved targeted detection and real-time ultrasound guided therapy for aortic vasa vasorum inflammation and neovascularization in animal models. Therefore, CEUS is uniquely suited to comprehensively assess and potentially treat aortic vascular diseases in the future.

Contrast-enhanced ultrasound characterization of the vascularity of the rotator cuff tendon: Age- and activity-related changes in the intact asymptomatic rotator cuff

2008 ◽  
Vol 17 (1) ◽  
pp. S96-S100 ◽  
Author(s):  
Jonas R. Rudzki ◽  
Ronald S. Adler ◽  
Russell F. Warren ◽  
Warren R. Kadrmas ◽  
Nikhail Verma ◽  
...  
Keyword(s):  
Rotator Cuff ◽  
Contrast Enhanced Ultrasound ◽  
Rotator Cuff Tendon ◽  
Contrast Enhanced

scholarly journals Imaging features of hepatic angiomyolipomas on real-time contrast-enhanced ultrasound

2010 ◽  
Vol 83 (989) ◽  
pp. 411-418 ◽  
Author(s):  
Z Wang ◽  
H-X Xu ◽  
X-Y Xie ◽  
X-H Xie ◽  
M Kuang ◽  
...  
Keyword(s):  
Real Time ◽  
Imaging Features ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced

The role of quantitation of real-time 3-dimensional contrast-enhanced ultrasound in detecting microvascular invasion: an in vivo study

2016 ◽  
Vol 41 (10) ◽  
pp. 1973-1979 ◽  
Author(s):  
Zhu Wang ◽  
Wei Wang ◽  
Guang-Jian Liu ◽  
Zheng Yang ◽  
Li-Da Chen ◽  
...  
Keyword(s):  
Real Time ◽  
Microvascular Invasion ◽  
In Vivo Study ◽  
Contrast Enhanced Ultrasound ◽  
3 Dimensional ◽  
Contrast Enhanced

scholarly journals Quantification of Cerebral Perfusion With “Real-Time” Contrast-Enhanced Ultrasound

Circulation ◽  
2001 ◽  
Vol 104 (21) ◽  
pp. 2582-2587 ◽  
Author(s):  
Se-Joong Rim ◽  
Howard Leong-Poi ◽  
Jonathan R. Lindner ◽  
Daniel Couture ◽  
Dilantha Ellegala ◽  
...  
Keyword(s):  
Real Time ◽  
Cerebral Perfusion ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced
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