scholarly journals Antileishmanial Activity of Medicinal Plants Used in Endemic Areas in Northeastern Brazil

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Aline Cavalcanti De Queiroz ◽  
Thays de Lima Matos Freire Dias ◽  
Carolina Barbosa Brito Da Matta ◽  
Luiz Henrique Agra Cavalcante Silva ◽  
João Xavier de Araújo-Júnior ◽  
...  

This study investigates the leishmanicidal activity of five species of plants used in folk medicine in endemic areas of the state of Alagoas, Brazil. Data were collected in the cities of Colonia Leopoldina, Novo Lino, and União dos Palmares, Alagoas state, from patients with cutaneous leishmaniasis (Leishmania amazonensis) who use medicinal plants to treat this disease. Plants extracts were tested at a concentration of 1–100 μg/mL in all experiments, except in an assay to evaluate activity against amastigotes, when 10 μg/mL was used. All plants extracts did not show deleterious activity to the host cell evidenced by LDH assay at 100, 10, and 1 μg/mL after 48 h of incubation. The plants extractsHyptis pectinata(L.) Poit,Aloe veraL.,Ruta graveolensL.,Pfaffia glomerata(Spreng.) Pedersen, andChenopodium ambrosioidesL. exhibited direct activity against extracellular forms at 100 μg/mL; these extracts inhibited growth by 81.9%, 82.9%, 74.4%, 88.7%, and 87.4%, respectively, when compared with promastigotes. The plants extractsH. pectinata, A. vera,andR. graveolensalso significantly diminished the number of amastigotes at 10 μg/mL, inhibiting growth by 85.0%, 40.4%, 94.2%, and 97.4%, respectively, when compared with control. Based on these data, we conclude that the five plants exhibited considerable leishmanicidal activity.

2017 ◽  
Vol 2 (2) ◽  
pp. 144-159 ◽  
Author(s):  
Paulo Henrique da Silva ◽  
Ykaro Richard Oliveira ◽  
Maria Carolina de Abreu

Este estudo direcionou-se a inventariar as plantas úteis cultivadas em quintais na comunidade rural de Aroeiras, município de Monsenhor Hipólito-PI, alocar as espécies citadas em categorias de uso, bem como delinear o perfil socioeconômico dos envolvidos na pesquisa, para assim conhecer e registrar o conhecimento tradicional local. O trabalho de campo foi realizado de fevereiro a maio de 2014, mediante entrevistas semi-estruturadas, fazendo uso do método bola-de-neve para a seleção dos participantes. Utilizou-se também a técnica da turnê-guiada pelos quintais e, simultâneo ao levantamento de dados, foram coletadas amostras das plantas citadas, as quais foram herborizadas segundo técnicas usuais em taxonomia vegetal, onde o sistema de classificação APG III foi o adotado. Dos 71 indivíduos entrevistados, 87,32% pertencem ao sexo feminino. Foram levantadas 188 espécies, pertencentes a 68 famílias, onde as mais representativas foram a Fabaceae e Lamiaceae. Quanto às categorias de uso, a ornamental, medicinal e alimentar foram as mais representativas. Chenopodium ambrosioides, Aloe vera e Ruta graveolens foram as espécies em que se encontrou os maiores valores de uso para a localidade estudada


2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Nazmul Hussain ◽  
Rony Chanda ◽  
Ruhshan Ahmed Abir ◽  
Mohsina Akter Mou ◽  
Md. Kamrul Hasan ◽  
...  

Abstract Objective MPDB 2.0 is built to be the continuation of MPDB 1.0, to serve as a more comprehensive data repertoire for Bangladeshi medicinal plants, and to provide a user-friendly interface for researchers, health practitioners, drug developers, and students who wish to study the various medicinal & nutritive plants scattered around Bangladesh and the underlying phytochemicals contributing to their efficacy in Bangladeshi folk medicine. Results MPDB 2.0 database (https://www.medicinalplantbd.com/) comprises a collection of more than five hundred Bangladeshi medicinal plants, alongside a record of their corresponding scientific, family, and local names together with their utilized parts, information regarding ailments, active compounds, and PubMed ID of related publications. While medicinal plants are not limited to the borders of any country, Bangladesh and its Southeast Asian neighbors do boast a huge collection of potent medicinal plants with considerable folk-medicinal history compared to most other countries in the world. Development of MPDB 2.0 has been highly focused upon human diseases, albeit many of the plants indexed here can serve in developing biofuel (e.g.: Jatropha curcas used in biofuel) or bioremediation technologies (e.g.: Amaranthus cruentus helps to reduce cadmium level in soil) or nutritive diets (Terminalia chebula can be used in nutritive diets) or cosmetics (Aloe vera used in cosmetics), etc.


2015 ◽  
Vol 13 (2) ◽  
pp. 91
Author(s):  
Adriana Elizabeth Reyes Parrado

<p>Las Ciencias Naturales son cruciales para procesos de aprendizaje en temas de conservación, medio ambiente y rescate cultural. Como parte de este proceso, estudiantes campesinos realizaron encuestas etnobotánicas en sus comunidades, encontrando 57 especies de plantas empleadas para diversas aplicaciones medicinales. Aquí se reportan su identidad taxonómica, las formas de preparación y los usos empleados por los habitantes. Las familias más representativas fueron Lamiaceae (19%), Asteraceae (14%), Apiaceae (7%), Rutaceae (5%), Verbenaceae (5%), Umbelliferae (3%) y Fabaceae (3%). Dentro de  las especies más empleadas estaban la <em>Mentha  piperita </em> (15,3%), <em>Aloe vera</em> (8,3%), <em>Chenopodium  </em><em>anthelminthium</em> (6,4%), <em>Rosmarinus officinalis </em> (5,8%), <em>Ocimum michrantum </em> (5,2%), <em>Ruta graveolens</em> (5%), <em>Melissa officinalis</em> (5%) y <em>Cymbopogon citratus </em> (5%). Los resultados obtenidos demuestran que los conocimientos tradicionales sobre plantas medicinales, está fuertemente arraigado en las comunidades rurales y que a pesar de la ampliación de cobertura en salud estos saberes aún persisten.</p><p> </p><p>The Natural Sciences are crucial to learning processes in conservation, environment and cultural recovery. As part of this process, students conducted ethnobotanical surveys in rural communities, finding 57 species of medicinal plants used for various applications. Here are reported taxonomic identity, forms of preparation and applications used by the inhabitants. The most representative families were Lamiaceae (19%), Asteraceae (14%), Apiaceae (7%), Rutaceae (5%), Verbenaceae (5%), Umbelliferae (3%) and Fabaceae (3%). Among the species most used were the Mentha piperita (15.3%), Aloe vera (8.3%), Chenopodium anthelminthium (6.4%), Rosmarinus officinalis (5.8%), Ocimum michrantum (5.2 %), Ruta graveolens (5 %), Melissa officinalis (5 %) and Cymbopogon citratus (5 %). The results show that traditional knowledge about medicinal plants, is deeply rooted in rural communities and that despite the expansion of health coverage this knowledge still persist.</p><p> </p><p> </p>


2021 ◽  
Vol 2021 ◽  
pp. 1-16
Author(s):  
Ezequiel da Costa Ferreira ◽  
Maria da Glória Vieira Anselmo ◽  
Natan Medeiros Guerra ◽  
Camilla Marques de Lucena ◽  
Cattleya do Monte Pessoa Felix ◽  
...  

The use of medicinal plants is an important source of therapeutic resources in rural communities and the wide versatility of some species may attract interest for prospecting studies. The aim of this study was to record and analyze local knowledge and the use of medicinal plants in the rural community of Malícia, municipality of Araçagi, Paraíba State, Northeastern Brazil, applying quantitative methods to calculate the Relative Importance (RI) and the Informant Consensus Factor (ICF). Semistructured interviews were conducted with 46 heads of households. The interviews addressed questions about the used parts of the plants, therapeutic indications, and form of use. Therapeutic indications were classified into categories of body systems. The Relative Importance Index (RI) was calculated to verify the species versatility, and the Informant Consensus Factor (ICF) was calculated to verify the consensus of use among informants regarding the body systems. A total of 111 plant species were recorded, inside 101 genera and 47 families. Fabaceae (16 spp.), Lamiaceae, and Myrtaceae (each one with 7 spp.) were the most representative families. Mentha arvensis, Aloe vera, and Myracrodruon urundeuva had the highest RI. A high consensus of use was observed among the informants for neoplasms, nervous system diseases, and infectious and parasitic diseases. Leaves were the part most cited for medicinal use. Regarding the method of preparation, the decoction and the oral administration route stood out. Neoplasms and respiratory system diseases had the highest ICF values. The results indicate a diversified knowledge of the local pharmacopeia and the need for in-depth studies to corroborate the effectiveness of medicinal plants and to understand the dynamics of local knowledge.


Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
JP Ferreira-Neto ◽  
RJSA Padilha ◽  
ERB Santana ◽  
DN Gomes ◽  
KXFR Sena ◽  
...  

Author(s):  
Kamal Solati ◽  
Mehrdad Karimi ◽  
Mahmoud Rafieian-Kopaei ◽  
Naser Abbasi ◽  
Saber Abbaszadeh ◽  
...  

: Wound healing is a process which starts with inflammatory response after damage occurrence. This process happens by restoring the wound surface coating tissue, migrating fibroblasts to form the needed collagen, forming a healing tissue and finally contortion and extraction of the wound. Today, various drugs are used to heal the wound. However, the used drugs to repair wounds have some defects and side effects. In spite of all attempts to accelerate wound healing definitely, no safe drug has been introduced for this purpose. Therefore, the necessity of identifying herbal plants in ethnopharmacology and ethnobotany documents with healing effect is felt essential. In this article we tried to review and present Iranian effective medicinal plants and herbal compounds used for wound healing. Searching was performed on databases including ISI Web of Science, PubMed, PubMed Central, Scopus, ISC, SID, Magiran and some other databases. The keywords used included wound healing, skin treatment, medicinal plants, ethnobotany, and phytotherapy. In this regard, 139 effective medicinal plants on wound healing were identified based on ethnopharmacology and ethnobotanical sources of Iran. Medicinal plants such as Salvia officinalis, Echium amoenum, Verbascum spp., G1ycyrrhiza glabra, Medicago sativa, Mentha pulegium, Datura stramonium L., Alhagi spp., Aloe vera, Hypericum perforatum, Pistacia atlantica and Prosopis cineraria were the most important and effective medicinal plants on wound healing in Iran. These native Iranian medicinal plants are full of antioxidants and biological compounds and might be used for wound healing and preparation of new drugs.


Viruses ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 744
Author(s):  
Iracema J. A. A. Jacques ◽  
Leila Katz ◽  
Marília A. Sena ◽  
Ana B. G. Guimarães ◽  
Yasmim L. Silva ◽  
...  

The diagnostic of arbovirus-related obstetric complications in high-risk pregnancy and childbirth care is challenging, especially in endemic areas. We conducted a prospective study to track active or recent Zika (ZIKV), dengue (DENV), or chikungunya (CHIKV) virus infection among hospitalized pregnant women (PW) with obstetric complications in a hospital at the epicenter of Zika outbreak and ZIKV-related microcephaly in Brazil. Clinical data and blood samples were collected at enrollment and 10 days after the admission of study participants, between October 2018 and May 2019. Further clinical data were extracted from medical records. Samples were screened by molecular and serological tests. Out of 780 participants, 93.1% (95% CI: 91.1–94.7%) presented previous DENV exposure (IgG). ZIKV, CHIKV, and/or DENV laboratory markers of recent or active infection were detected in 130 PW, yielding a prevalence of 16.6% (95% CI: 14.2–19.5%); 9.4% (95% CI: 7.4–11.7%), 7.4% (95% CI: 5.7–9.7%), and 0.38% (95% CI: 0.1–1.2%) of CHIKV, ZIKV, and DENV infections, respectively. Most ZIKV infections were detected by molecular assays (89.6%), while CHIKV infections were detected by serology (95.9%). Our findings highlight the need for arbovirus infections screening in PW with obstetrical complications, potentially associated to these infections in endemic areas regardless of the signs or symptoms suggestive of arboviral disease.


2011 ◽  
Vol 33 (1) ◽  
Author(s):  
Germano Leão Demolin Leite ◽  
Flávia Silva Barbosa ◽  
Sérgio Monteze Alves ◽  
Aline Fonseca Nascimento ◽  
Vinícius De Abreu D'Ávila ◽  
...  

2013 ◽  
Vol 15 (1) ◽  
pp. 142-149 ◽  
Author(s):  
F.S. Barbosa ◽  
G.L.D. Leite ◽  
E.R. Martins ◽  
V.A. D'avila ◽  
V.M Cerqueira

The aim of this study was to evaluate the insecticidal effect of aqueous, alcoholic, and oil extracts from leaves of eight medicinal plants against Diabrotica speciosa prepared at five concentrations. The extracts that used commercial soybean oil as solvent showed the highest D. speciosa mortality due to the solvent itself, regardless of the used plants and their concentrations. Thus, commercial soybean oil was discarded as solvent since at these volumes it would cause serious phytotoxicity problems. After 24 hours of exposure of the pest to the extracts, the highest D. speciosa mortality values were observed for Copaifera langsdorfii and Chenopodium ambrosioides extracts, both in 5% alcohol, and Artemisia verlotorum, in 10% water. However, in the last mortality assessment (48 h), C. langsdorfii extract in 5% alcohol showed higher mortality of this pest, followed by C. ambrosioides extract in 5% alcohol, compared to the remaining plants.


2012 ◽  
Vol 45 (4) ◽  
pp. 510-513 ◽  
Author(s):  
Teiliane Rodrigues Carneiro ◽  
Marta Cristhiany Cunha Pinheiro ◽  
Sara Menezes de Oliveira ◽  
Ana Lúcia de Paula Hanemann ◽  
José Ajax Nogueira Queiroz ◽  
...  

INTRODUCTION: The laboratory diagnosis of schistosomiasis is based mainly on the detection of parasite eggs in stool samples through the Kato-Katz (KK) technique, reading one slide by test. However, a widely known limitation of parasitological methods is reduced sensitivity, particularly in low endemic areas. METHODS: To increase sensitivity, we conducted further slide readings from the same stool sample using the parasitological method associated with a serological test. We used the KK method (three slides) and the IgG anti-Schistosoma mansoni-enzyme-linked immunosorbent assay (ELISA) technique to diagnose schistosomiasis in low endemic areas in the Brazilian State of Ceará. Fecal samples and sera from 250 individuals were analyzed. RESULTS: Sixteen percent and 47.2% of samples were positive in parasitological tests and serological tests, respectively. Parasitological methods showed that 32 (80%) individuals tested positive on the first slide, 6 (15%) on the second slide, and 2 (5%) on the third. The performance of the ELISA test in the diagnosis, using the KK method as diagnostic reference, showed a negative predictive value of 100%, with specificity and positive predictive values of 62.8% and 33.9%, respectively. CONCLUSIONS: In this study, the increase from one to three slides analyzed per sample using the KK technique was shown to be a useful procedure for increasing the diagnostic sensitivity of this technique.


Sign in / Sign up

Export Citation Format

Share Document