scholarly journals Scattering Coefficients of Mice Organs Categorized Pathologically by Spectral Domain Optical Coherence Tomography

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Q. Q. Zhang ◽  
X. J. Wu ◽  
C. Wang ◽  
S. W. Zhu ◽  
Y. L. Wang ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Curve Fitting ◽  
Spectral Domain ◽  
Scattering Coefficient ◽  
Optical Coherence ◽  
Tissue Specific ◽  
Tissue Density ◽  
Tissue Diagnosis ◽  
Scattering Coefficients

Differences in tissue density cause a variety of scattering coefficients. To quantify optical coherence tomography (OCT) images for diagnosis, the tissue's scattering coefficient is estimated by curve fitting the OCT signals to a confocal single backscattering mode. The results from a group of 30 mice show that the scattering coefficients of bone, skin, liver, brain, testis, and spleen can be categorized into three groups: a scattering coefficient between 1.947 and 2.134 mm−1: bone and skin; a scattering coefficient between 1.303 and 1.461 mm−1: liver and brain; a scattering coefficient between 0.523 and 0.634 mm−1: testis and spleen. The results indicate that the scattering coefficient is tissue specific and could be used in tissue diagnosis.

scholarly journals Quantitative Diagnosis of Colorectal Polyps by Spectral Domain Optical Coherence Tomography

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Chen Wang ◽  
Qinqin Zhang ◽  
Xiaojing Wu ◽  
Tao Tang ◽  
Hong Liu ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Early Diagnosis ◽  
Colorectal Polyp ◽  
Primary Diagnosis ◽  
Colorectal Polyps ◽  
Spectral Domain ◽  
Scattering Coefficient ◽  
Optical Coherence ◽  
Scattering Coefficients ◽  
Spectral Domain Oct

The principal aim of this study is to investigate the scattering coefficient of colorectal polyp tissues using an optical coherence tomography (OCT) technique. It combines the existing scattering coefficient model and spectral domain OCT to achieve method of early diagnosis of colorectal polyp in hospitals. Seventeen patients were studied, and a total of 1456 data points were extracted by curve-fitting the OCT signals into a confocal single-backscattering model. The results show that the mean scattering coefficient value for colorectal polyps is 1.91 mm−1(std: ±0.54 mm−1), which is between the values for normal and malignant tissues. In addition, we studied the difference between adenomatous polyps (n=15) and inflammatory polyps (n=2) quantitatively and found that the adenomatous tissues had lower scattering coefficients than the inflammatory ones. The quantitative measurements confirmed that OCT can be used in primary diagnosis to compensate for the deficiencies in methods of pathological diagnosis, with a great potential for early diagnosis of tissues.

CHARACTERIZATION OF VITILIGO BY IN VIVO SCATTERING COEFFICIENT OF HUMAN SKIN

2011 ◽  
Vol 04 (01) ◽  
pp. 67-72 ◽  
Author(s):  
WANRONG GAO ◽  
PENG LEE ◽  
XIANLING ZHANG
Keyword(s):  
Optical Coherence Tomography ◽  
Human Skin ◽  
Experimental Results ◽  
Scattering Coefficient ◽  
Optical Coherence ◽  
Scattering Coefficients ◽  
Significant Difference

Scattering coefficients of human skin in vivo with and without vitiligo were measured with optical coherence tomography (OCT). The experimental results show that there exist significant difference between the scattering coefficient of the epidermis of in vivo human skin with and without vitiligo disease. The results may be helpful for quantitatively diagnosing or evaluating the treatment of the disease.

Is high-resolution spectral domain optical coherence tomography reliable in nystagmus?

2011 ◽  
Vol 97 (4) ◽  
pp. 534.1-536 ◽  
Author(s):  
Mervyn G Thomas ◽  
Anil Kumar ◽  
John R Thompson ◽  
Frank A Proudlock ◽  
Kees Straatman ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
High Resolution ◽  
Spectral Domain ◽  
Optical Coherence

Repeatability of Spectral Domain Optical Coherence Tomography Measurements in High Myopia

2016 ◽  
Vol 25 (5) ◽  
pp. e526-e530 ◽  
Author(s):  
Harsha L. Rao ◽  
Addepalli U. Kumar ◽  
Sampath R. Bonala ◽  
Kadam Yogesh ◽  
Bodduluri Lakshmi
Keyword(s):  
Optical Coherence Tomography ◽  
High Myopia ◽  
Spectral Domain ◽  
Optical Coherence
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