scholarly journals Coronary Heart Disease in Postmenopausal Women with Type II Diabetes Mellitus and the Impact of Estrogen Replacement Therapy: A Narrative Review

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Marouane Boukhris ◽  
Salvatore Davide Tomasello ◽  
Francesco Marzà ◽  
Sonia Bregante ◽  
Francesca Romana Pluchinotta ◽  
...  

Coronary heart disease is the main cause of death in postmenopausal women (PMW); moreover its mortality exceeds those for breast cancer in women at all ages. Type II diabetes mellitus is a major cardiovascular risk factor and there is some evidence that the risk conferred by diabetes is greater in women than in men. It was established that the deficiency of endogenous estrogens promotes the atherosclerosis process. However, the impact of estrogen replacement therapy (ERT) on cardiovascular prevention remains controversial. Some authors strongly recommend it, whereas others revealed a concerning trend toward harm. This review tries to underlines the different components of cardiovascular risk in diabetic PMW and to define the place of ERT.

2007 ◽  
Vol 30 (1) ◽  
pp. 120-127 ◽  
Author(s):  
Majidreza Kamyar ◽  
B. Julienne Johnson ◽  
John J. McAnaw ◽  
Rosa Lemmens-Gruber ◽  
Steve A. Hudson

2021 ◽  
pp. 28-30
Author(s):  
О. О. Pogrebniak

The features of the vasoregulating function of the vascular endothelium have been determined and correlations between haemodynamic and metabolic indices have been established in patients with coronary heart disease associated with type II diabetes mellitus. In patients with coronary heart disease associated with type II diabetes mellitus in comparison with patients without an association with diabetes mellitus significantly higher indices of the content of the blood fibrinogen the diameter of the brachial artery (after decompression) were observed. Direct correlations between fasting glycemia and microalbuminuria and reverse correlations with the endothelial dependent vasodilatation (EDVA), fasting glucemia, the blood content of glycosylated hemoglobin and very low density lipoproteins have been found.


2005 ◽  
Vol 20 (2) ◽  
pp. 75-80 ◽  
Author(s):  
H. Surekha Rani ◽  
G. Madhavi ◽  
V. Ramachandra Rao ◽  
B. K. Sahay ◽  
A. Jyothy

1997 ◽  
Vol 43 (5) ◽  
pp. 47-50
Author(s):  
M. M. Ginzburg ◽  
G. S. Kozupitsa

Obesity is now the most common disease in the population of economically developed countries, where up to 25% of residents have a body weight that is more than 15% higher than normal [8]. An increase in the incidence rate of about 10% over 10 years is observed [33]. The causal relationship between obesity and arterial hypertension, coronary heart disease, and type II diabetes mellitus is well known [6, 10]. At the same time, the current state of the problem of prevention, therapy and control of relapse of obesity is far from perfect. And this is primarily due to the fact that we do not fully know the pathogenesis of this disease.


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