scholarly journals Adolescent Catatonia Successfully Treated with Lorazepam and Aripiprazole

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Aaron J. Roberto ◽  
Subhash Pinnaka ◽  
Abhishek Mohan ◽  
Hiejin Yoon ◽  
Kyle A. B. Lapidus
Keyword(s):  
Case Report ◽  
Children And Adolescents ◽  
Emotional Distress ◽  
Successful Treatment ◽  
Previous History ◽  
Treatment Modalities ◽  
Psychotic Symptoms ◽  
First Episode ◽  
Significant Impairment ◽  
History Of

Catatonia is especially concerning in children and adolescents. It leads to significant impairment, including emotional distress, difficulty communicating, and other debilitating symptoms. In this case report, we discuss a patient with no previous history of neuroleptic medication or psychotic symptoms, presenting with first-episode catatonia in the presence of disorganized, psychotic thoughts. We then review the catatonia syndrome, citing examples in the literature supporting its underdiagnosis in children and adolescents, and discuss successful treatment modalities. It is important to diagnose and treat catatonia as efficiently as possible, to limit functional and emotional distress to the patient.

scholarly journals First-Episode of Synthetic Cannabinoid-Induced Psychosis in a Young Adult, Successfully Managed with Hospitalization and Risperidone

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Aaron J. Roberto ◽  
Aileen Lorenzo ◽  
Kevin J. Li ◽  
Jonathan Young ◽  
Abhishek Mohan ◽  
...  
Keyword(s):  
Emotional Distress ◽  
Relevant Literature ◽  
Synthetic Cannabinoids ◽  
Previous History ◽  
Health Concern ◽  
Psychotic Symptoms ◽  
First Episode ◽  
Episode Psychosis ◽  
Significant Impairment ◽  
History Of

Synthetic cannabinoids- (SCs-) induced psychosis is a growing public health concern. It leads to significant impairment, including emotional distress, difficulty communicating, and other debilitating symptoms. In this case report, we discuss a patient with no previous history of psychotic symptoms, presenting with first-episode psychosis in the context of progressive, acutely worsening, disorganized, psychotic thoughts and behaviors following prolonged use of SCs. We also discuss relevant literature on SCs-induced psychosis, highlighting its prevalence, presentation, diagnosis, and recommended management. It is important to diagnose and treat SCs-induced psychosis as early and efficiently as possible, in order to alleviate symptoms while limiting functional impairment and emotional distress to the patient.

Popliteal artery thrombosis secondary to a tibial osteochondroma

VASA ◽  
2011 ◽  
Vol 40 (3) ◽  
pp. 251-255 ◽  
Author(s):  
Gruber-Szydlo ◽  
Poreba ◽  
Belowska-Bien ◽  
Derkacz ◽  
Badowski ◽  
...  
Keyword(s):  
Case Report ◽  
Magnetic Resonance Angiography ◽  
Popliteal Artery ◽  
Doppler Ultrasonography ◽  
Histopathological Examination ◽  
Previous History ◽  
Plain Radiography ◽  
Artery Thrombosis ◽  
History Of ◽  
The Right

Popliteal artery thrombosis may present as a complication of an osteochondroma located in the vicinity of the knee joint. This is a case report of a 26-year-old man with symptoms of the right lower extremity ischaemia without a previous history of vascular disease or trauma. Plain radiography, magnetic resonance angiography and Doppler ultrasonography documented the presence of an osteochondrous structure of the proximal tibial metaphysis, which displaced and compressed the popliteal artery, causing its occlusion due to intraluminal thrombosis..The patient was operated and histopathological examination confirmed the diagnosis of osteochondroma.

scholarly journals Mild SARS-CoV-2 Infection After Gene Therapy in a Child With Wiskott-Aldrich Syndrome: A Case Report

2020 ◽  
Vol 11 ◽  
Author(s):  
Sabina Cenciarelli ◽  
Valeria Calbi ◽  
Federica Barzaghi ◽  
Maria Ester Bernardo ◽  
Chiara Oltolini ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Case Report ◽  
Immune Reconstitution ◽  
Autoinflammatory Disease ◽  
Clinical Phenotype ◽  
High Titer ◽  
Previous History ◽  
Wiskott Aldrich Syndrome ◽  
Neutralizing Capacity ◽  
History Of

In this work we present the case of SARS-CoV-2 infection in a 1.5-year-old boy affected by severe Wiskott-Aldrich Syndrome with previous history of autoinflammatory disease, occurring 5 months after treatment with gene therapy. Before SARS-CoV-2 infection, the patient had obtained engraftment of gene corrected cells, resulting in WASP expression restoration and early immune reconstitution. The patient produced specific immunoglobulins to SARS-CoV-2 at high titer with neutralizing capacity and experienced a mild course of infection, with limited inflammatory complications, despite pre-gene therapy clinical phenotype.

scholarly journals A profile of adult acute admissions to Lentegeur Psychiatric Hospital, South Africa

2019 ◽  
Vol 25 ◽  
Author(s):  
Herman Franken ◽  
John Parker ◽  
Robin Allen ◽  
Robert A. Wicomb
Keyword(s):  
South Africa ◽  
Psychiatric Hospital ◽  
Common Mental Disorders ◽  
Psychotic Symptoms ◽  
First Episode ◽  
Western Cape ◽  
Violent Behaviour ◽  
Manic Symptoms ◽  
History Of ◽  
Clinical Records

Background: The Western Cape province has the highest documented lifetime prevalence of common mental disorders in South Africa. To ensure the efficient, equitable and effective distribution of current resources, there is a need to determine the profile of patients requiring psychiatric admission.Aim: To describe patients admitted to the acute adult admissions unit at Lentegeur Hospital.Setting: Lentegeur Psychiatric Hospital is situated in Mitchells Plain, Cape Town, and serves about 1 million people from nearby urban and rural areas.Methods: This retrospective study involved an audit of all patients (18–60 years of age) admitted between 01 January 2016 and 30 June 2016. The clinical records of 573 adult patients were examined.Results: The median age of the cohort was 29 years. Most patients (63%) were educated to the secondary level. Only 12% of the patients were employed, and 37% received disability grants. More than 90% of the patients presented with psychotic symptoms. Of these, 28% presented with a first-episode of psychosis. Of all patients, 20% were referred with manic symptoms and 7% with depressive symptoms. Many patients (62%) used substances concurrently in the period leading up to admission. Significantly more males (73%) used substances compared to females (38%). Cannabis was the most widely used substance (51%), followed by methamphetamine (36%). Recent violent behaviour contributed to 37% of the current admissions. A total of 70 patients (13%) tested positive for human immunodeficiency virus (HIV), and 49 (9%) tested positive for syphilis.Conclusion: Substance use and a history of violence contributed to admissions in this population.

Self-Monitoring, Competing Response and Response Cost in the Treatment of Trichotillomania: A Case Report

1997 ◽  
Vol 25 (3) ◽  
pp. 281-290 ◽  
Author(s):  
Paul Rogers ◽  
Simon Darnley
Keyword(s):  
Case Report ◽  
Female Patient ◽  
Successful Treatment ◽  
Response Cost ◽  
Hair Pulling ◽  
Self Monitoring ◽  
History Of ◽  
Competing Response

Self-monitoring, a competing response and response cost were used in the successful treatment of a 49 year old female patient with a 19 year history of trichotillomania. Self-monitoring and a competing response produced significant decreases in hair-pulling, but still continued as the patient found it pleasurable at times of stress. The addition of response cost procedures overcame this.

scholarly journals Unusual cranial trauma caused by pencil in teenager: case report

2017 ◽  
Vol 31 (4) ◽  
pp. 545-550
Author(s):  
Amer Saeed Rashid ◽  
Saif Saood Abdelrazaq ◽  
Samer S. Hoz ◽  
Huber Padilla ◽  
Ramos-Villegas Yancarlos ◽  
...  
Keyword(s):  
Case Report ◽  
Children And Adolescents ◽  
Temporal Lobe ◽  
Organic Material ◽  
Radiological Evaluation ◽  
Imaging Evaluation ◽  
Cranial Trauma ◽  
Urgent Surgery ◽  
Secondary Damage ◽  
History Of

Abstract Introduction: Penetrating lesions by pencil in the temporal lobe in children and adolescents are uncommon. We present the case of a teenager with penetrating injury by strange object in the temporal lobe. Case: Twelve years old male patient, with history of trauma while he was playing with his friends, presents alteration of the consciousness state, weakness in right hemibody and dysphasia. Urgent surgery is practiced employing an incision in “C” form with improvement of the consciousness state during post-operative. Discussion: Penetrating lesions in the skull and brain are classified as missiles and non-missiles depending of their impact velocity. The wood is a porous organic material that provide a natural deposit of microbian agents, making it potentially lethal. Pre-operative radiological evaluation allows check the trajectory of the penetrating object and secondary lesions present guiding de neurosurgical approach. The prognostic depends on penetration site, timely handling and complications associated. Conclusion: Penetrating lesions by pencil are uncommon, an appropriate imaging evaluation is fundamental to determine the neurosurgical approach that allows prevent and/or decrease secondary damage.

scholarly journals Fentanyl Abuse: A Literature Review

2020 ◽  
Vol 5 (1) ◽  
Keyword(s):  
Case Report ◽  
Community Acquired Pneumonia ◽  
Treatment Modalities ◽  
Opioid Overdose ◽  
Opioid Agonist ◽  
Polysubstance Use ◽  
Other Substances ◽  
Control And Prevention ◽  
Life Threatening ◽  
History Of

Background and Objectives: Fentanyl is an opioid agonist with abuse potential. The overdose can begin suddenly, progress to death rapidly, and may have an atypical presentation with body and chest wall rigidity. This article aims to review the consequences of fentanyl abuse alone or in combination with other substances along with available treatment modalities. Methods: A literature search using the keywords “opioid addiction” or “fentanyl abuse” and “fentanyl overdose” and “fentanyl treatment” was conducted on PubMed. Additional data was gathered from the Centers for Disease Control and Prevention and other websites. Finally, 32 out of 310 articles were selected for the review. Our case report highlights the consequences of fentanyl abuse in combination with other substances. Case report: A 32 years old Caucasian female with a history of polysubstance use was admitted for community-acquired pneumonia after overdosing with fentanyl, heroin, and cocaine. Results: Fentanyl is often mixed with other substances and sold as heroin to unsuspecting users. Its abuse may cause life-threatening respiratory failure from an overdose. Discussion and Conclusions: In 2016, approximately 50% who died from an opioid overdose in the US were taking fentanyl, and 57% of those who tested positive for fentanyl or its analogs were positive for other drugs such as heroin. Naloxone kits distribution has reported significant overdose reversals. Scientific Significance: Opioid crisis, declared as an emergency by the federal government, is affecting public health. Prescribers have a major role in reducing overdose deaths by prescribing the lowest, effective dose with the shortest treatment duration.

scholarly journals Nontuberculous Mycobacterial Endophthalmitis: Case Series and Review of Literature

2020 ◽  
Author(s):  
Warinyupa Pinitpuwadol ◽  
Nattaporn Tesavibul ◽  
Sutasinee Boonsophon ◽  
Darin Sakiyalak ◽  
Sucheera Sarunket ◽  
...  
Keyword(s):  
Previous History ◽  
Case Series ◽  
Clinical Information ◽  
Visual Outcome ◽  
Treatment Modalities ◽  
Endogenous Endophthalmitis ◽  
Treatment Regimens ◽  
Department Of Ophthalmology ◽  
History Of ◽  
Exogenous Endophthalmitis

Abstract Background: To report three cases of nontuberculous mycobacterial (NTM) endophthalmitis following multiple ocular surgeries and to review previous literature in order to study the clinical profile, treatment modalities, and visual outcomes among patients with NTM endophthalmitis.Methods: Clinical manifestation and management of patients with NTM endophthalmitis in the Department of Ophthalmology, Faculty of Medicine, Siriraj hospital, Mahidol University, Bangkok, Thailand were described. In addition, a review of previously reported cases and case series from MEDLINE, EMBASE, and CENTRAL was performed. The clinical information and type of NTM from the previous studies and our cases were summarized.Results: We reported three cases of NTM endophthalmitis caused by M. haemophilum, M. fortuitum and M. abscessus and a summarized review of 112 additional cases previously published. Of 115 patients, there were 101 exogenous endophthalmitis (87.8%) and 14 endogenous endophthalmitis (12.2%). The patients’ age ranged from 13 to 89 years with mean of 60.5±17.7 years with no gender predominance. Exogenous endophthalmitis occurred in both healthy and immunocompromised hosts, mainly caused by cataract surgery (67.3%). In contrast, almost all endogenous endophthalmitis patients were immunocompromised. Among all patients, previous history of tuberculosis infection was identified in 4 cases (3.5%). Rapid growing NTMs were responsible for exogenous endophthalmitis, while endogenous endophthalmitis were commonly caused by slow growers. Treatment regimens consisted of macrolides, fluoroquinolones or aminoglycosides, which were continued for up to 12 months. Initial and final vision were generally worse than 6/60.Conclusions: NTM endophthalmitis is a serious intraocular infection that leads to irreversible loss of vision. The presentation can mimic a chronic recurrent or persistent intraocular inflammation. History of multiple intraocular surgeries or immune-deficiency in patient with chronic panuveitis should raise the practioner’s suspicion of NTM endophthalmitis. Appropriate diagnosis and treatment are important to optimize visual outcome.

scholarly journals Nontuberculous Mycobacterial Endophthalmitis: Case Series and Review Literature

2020 ◽  
Author(s):  
Warinyupa Pinitpuwadol ◽  
Nattaporn Tesavibul ◽  
Sutasinee Boonsophon ◽  
Darin Sakiyalak ◽  
Sucheera Sarunket ◽  
...  
Keyword(s):  
Previous History ◽  
Case Series ◽  
Clinical Information ◽  
Visual Outcome ◽  
Review Literature ◽  
Treatment Modalities ◽  
Endogenous Endophthalmitis ◽  
Department Of Ophthalmology ◽  
History Of ◽  
Exogenous Endophthalmitis

Abstract Background: To report three cases of nontuberculous mycobacterial (NTM) endophthalmitis following multiple ocular surgeries and to review previous literature in order to study the clinical profile, treatment modalities, and visual outcomes among patients with NTM endophthalmitis.Methods: Clinical manifestation and management of patients with NTM endophthalmitis in the Department of Ophthalmology, Faculty of Medicine, Siriraj hospital, Mahidol University, Bangkok, Thailand were described. In addition, a review of previously reported cases and case series from MEDLINE, EMBASE, and CENTRAL was performed. The clinical information and type of NTM from the previous studies and our cases were summarized.Results: We reported three cases of NTM endophthalmitis caused by M. haemophilum, M. fortuitum and M. abscessus and a summarized review of 112 additional cases previously published. Of 115 patients, there were 101 exogenous endophthalmitis (87.8%) and 14 endogenous endophthalmitis (12.2%). The patients’ age ranged from 13 to 89 years with mean of 60.5±17.7 years with no gender predominance. Exogenous endophthalmitis occurred in both healthy and immunocompromised hosts, mainly caused by cataract surgery (67.3%). In contrast, almost all endogenous endophthalmitis patients were immunocompromised. Among all patients, previous history of tuberculosis infection was identified in 4 cases (3.5%). Rapid growing NTMs were responsible for exogenous endophthalmitis, while endogenous endophthalmitis were commonly caused by slow growers. Treatment regimens consisted of macrolides, fluoroquinolones or aminoglycosides, which were continued for up to 12 months. Initial and final vision were generally worse than 6/60.Conclusions: NTM endophthalmitis is a serious intraocular infection that leads to irreversible loss of vision. The presentation can mimic a chronic recurrent or persistent intraocular inflammation. History of multiple intraocular surgeries or immune-deficiency in patient with chronic panuveitis should raise the practioner’s suspicion of NTM endophthalmitis. Appropriate diagnosis and treatment are important to optimize visual outcome.

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