scholarly journals A CV Study of Copper Complexation with Guanine Using Glassy Carbon Electrode in Aqueous Medium

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Md. Sohel Rana ◽  
Mohammad Arifur Rahman ◽  
A. M. Shafiqul Alam
Keyword(s):  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Metal Ion ◽  
Supporting Electrolyte ◽  
Complex Mixture ◽  
Step Height ◽  
Rate Variation ◽  
Carbon Electrode ◽  
Copper Complexation ◽  
Scan Rate

Voltammetric behaviors of Copper (II) nitrogen bearing nucleobases, such as Guanine (C5H4N5O2) was studied in electro analyzer using cyclic voltammetry (CV) on a Glassy Carbon Electrode. Assessment of the chemical and physical conditions that may favor optimum current enhancement was done by studying the effect of variation of concentration of metal and ligand ions, variation of scan rate, variation of step height, variation of pH values, and variation of supporting electrolyte as (NH4)2SO4, KCl, and NaCl. It was observed that Copper and Guanine forms a 1 : 2 ratio complex. The work reflects that increasing the concentration of either metal ion or ligand ion increases the corresponding current. Increasing the scan rate increases the corresponding current linearly with the square root of the scan rate. As the step height decreases the peaks become sharp. Anodic and cathodic current increases linearly with decreasing step height. For the complex mixture the complexation occurs maximum at a pH of 2.3–7.0 and is badly restricted in the slightly alkaline medium and the complexing order of the supporting electrolyte showed a trend as (NH4)2SO4>NaCl>KCl.

scholarly journals Electrochemical Oxidation of Paracetamol Mediated byMgB2Microparticles Modified Glassy Carbon Electrode

2011 ◽  
Vol 8 (2) ◽  
pp. 553-560 ◽  
Author(s):  
Mohammed Zidan ◽  
Tan Wee Tee ◽  
A. Halim Abdullah ◽  
Zulkarnain Zainal ◽  
Goh Joo Kheng
Keyword(s):  
Cyclic Voltammetry ◽  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Supporting Electrolyte ◽  
Carbon Electrode ◽  
Modified Glassy Carbon Electrode ◽  
Diffusion Controlled ◽  
Scan Rate ◽  
Degree Of Stability ◽  
A Current

A MgB2microparticles modified glassy carbon electrode (MgB2/GCE) was fabricated by adhering microparticles of MgB2onto the electrode surface of GCE. It was used as a working electrode for the detection of paracetamol in 0.1 M KH2PO4aqueous solution during cyclic voltammetry. Use of the MgB2/GCE the oxidation process of paracetamol with a current enhancement significantly by about 2.1 times. The detection limit of this modified electrode was found to be 30 μM. The sensitivity under conditions of cyclic voltammetry is significantly dependent on pH, supporting electrolyte, temperature and scan rate. The current enhancement observed in different electrolytic media varied in the following order: KH2PO4> KCl > K2SO4> KBr. Interestingly, the oxidation of paracetamol using modified GC electrode remain constant even after 15 cycling. It is therefore evident that the MgB2modifiedGCelectrode possesses some degree of stability. A slope of 0.52 dependent of scan rate on current indicates that the system undergoes diffusion-controlled process.

scholarly journals Electrochemical Behaviour of a Gold Film- Glassy Carbon Electrode for Determination of Chromium (VI)

2021 ◽  
Author(s):  
Nevila Broli ◽  
Loreta Vallja ◽  
Majlinda Vasjari
Keyword(s):  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Electrochemical Behaviour ◽  
Supporting Electrolyte ◽  
Anodic Stripping Voltammetry ◽  
Carbon Electrode ◽  
Modulation Amplitude ◽  
Chromium Vi ◽  
Relative Standard

A gold nanostructured film modified glassy carbon electrode (Aufilm/GCE) was developed for the determination of chromium (VI) in water sample. GCE was immersed into HAuCl4 solution (10-3M) and electrodeposition of thin gold layer was conducted at –0.4 V (vs Ag/AgCl) for 10 min. The strong affinity between Au and Cr species resulted with increasing of Cr (VI) signal, compared with the bare glassy carbon electrode. The electrodepositing time, type of supporting electrolyte, pH, the scan rate, modulation amplitude, and modulation time were optimized using differential pulse anodic stripping voltammetry (DP-ASV). The calibration graph using accumulation time of 120 s was linear from 10 to 120 µgL-1 with a sensitivity 1.3 x 10-2 µA/µgL-1. Under optimum experimental conditions, a good correlation coefficient R2=0.9971, and a low detection limit 5.5 µg/L Cr (VI) was obtained. The signal was reproducible with a relative standard deviation ±4.5 %. The developed Aufilm/GCE sensor was applied for the Cr (VI) determination of in sewage water samples.

scholarly journals Glassy carbon and boron doped glassy carbon electrodes for voltammetric determination of linuron herbicide in the selected samples

2012 ◽  
Vol 10 (4) ◽  
pp. 1271-1279 ◽  
Author(s):  
Jelena Đorđević ◽  
Ana Kalijadis ◽  
Ksenija Kumrić ◽  
Zoran Jovanović ◽  
Zoran Laušević ◽  
...  
Keyword(s):  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Supporting Electrolyte ◽  
Electrochemical Determination ◽  
Temperature Treatment ◽  
Voltammetric Determination ◽  
Carbon Electrode ◽  
Glassy Carbon Electrodes ◽  
Boron Doped

AbstractIn this study the application of home-made unmodified (GC) and bulk modified boron doped glassy carbon (GCB) electrodes for the voltammetric determination of the linuron was investigated. The electrodes were synthesized with a moderate temperature treatment (1000°C). Obtained results were compared with the electrochemical determination of the linuron using a commercial glassy carbon electrode (GC-Metrohm). The peak potential (E p ) of linuron oxidation in 0.1 mol dm−3 H2SO4 as electrolyte was similar for all applied electrodes: 1.31, 1.34 and 1.28 V for GCB, GC and GC-Metrohm electrodes, respectively. Potential of linuron oxidation and current density depend on the pH of supporting electrolyte. Applying GCB and GC-Metrohm electrodes the most intensive electrochemical response for linuron was obtained in strongly acidic solution (0.1 mol dm−3 H2SO4). Applying the boron doped glassy carbon electrode the broadest linear range (0.005–0.1 µmol cm−3) for the linuron determination was obtained. The results of voltammetric determination of the linuron in spiked water samples showed good correlation between added and found amounts of linuron and also are in good agreement with the results obtained by HPLC-UV method. This appears to be the first application of a boron doped glassy carbon electrode for voltammetric determination of the environmental important compounds.

Determination of Drimarene Blue X-BLN at a glassy carbon electrode by differential pulse voltammetry

2011 ◽  
Vol 76 (12) ◽  
pp. 1765-1773 ◽  
Author(s):  
Abd-Elgawad M. Radi ◽  
Mohammed R. Mostafa ◽  
Reda M. Elshafey ◽  
Talaat A. Hegazy
Keyword(s):  
Differential Pulse Voltammetry ◽  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Supporting Electrolyte ◽  
Differential Pulse ◽  
Redox Couple ◽  
Carbon Electrode ◽  
Validation Parameters ◽  
Pulse Voltammetry

The electrochemical oxidation behaviour of Drimarene Blue X-BLN (DB) has been investigated in phosphate buffers (pH 2.54–10.18) by cyclic and differential pulse voltammetry (DPV) at a glassy carbon electrode (GCE). The oxidation of DB dye generated well-defined pH-dependent two pairs of quasi-reversible anodic-cathodic peak couples. DB exhibited the second redox couple over the entire pH range, while the first redox couple disappeared for pH ≥ 6.70. The redox processes were adsorption-controlled. An electroanalytical method was developed for the determination of DB in phosphate buffer solution (pH 2.85) as supporting electrolyte using DPV. The anodic current heights varied linearly with DB concentrations in the ranges 2 × 10–6–3 × 10–5 and 6 × 10–6–3 × 10–5 mol l–1 with limits of detection (LOD) of 8.7 × 10–7 and 5.7 × 10–7 mol l–1 and limits of quantification (LOQ) of 2.9 × 10–6 and 1.9 × 10–6 mol l–1 for the first and second anodic peaks, respectively. Validation parameters, such as accuracy, precision and recovery were evaluated. The proposed method was successfully applied to the determination of DB in tap water and the analytical results compared well with those obtained by the spectrophotometric method.

scholarly journals Electrochemical Determination of Furosemide Drug at Tranexamic Acid Gold Nanoparticles Modified Glassy Carbon Electrode

2021 ◽  
Vol 22 (1) ◽  
pp. 172-179
Author(s):  
Tasawar Ali Chandio
Keyword(s):  
Gold Nanoparticles ◽  
Tranexamic Acid ◽  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Supporting Electrolyte ◽  
Electrochemical Determination ◽  
Calibration Plot ◽  
Carbon Electrode ◽  
Modified Glassy Carbon Electrode

The reported work discussed the simpler and sensitive strategy for the electrochemical determination of furosemide by employed tranexamic acid derived gold nanoparticles modified glassy carbon electrode (GCE). The synthesis of tranexamic acid derived gold nanoparticles (Tr- AuNps) was carried out using single step approach. The synthesized Tr-AuNps were characterized by using atomic force microscopy (AFM), illustrated that the particles are spherical in shape with an average size of 35 nm. The synthesized AuNps have modified the sensing surface of GCE. The modified GCE demonstrated highly catalytic behavior for the oxidation of loop diuretic drug furosemide. The influence of pH and supporting electrolyte was examined and the working conditions were optimized. The amperometric determination of furosemide was also carried out at the Tr-AuNps modified GCE under stirred conditions using Britton Robinson buffer (BR buffer) as supporting electrolyte at pH 5. The linear calibration plot showed the dependence of the peak current on increasing concentrations of furosemide in the range of 50 μM to 500 μM furosemide with the detection limit of 5 μM. The proposed sensing plan has been successfully employed for the quantification of furosemide in human urine samples with satisfactory recoveries.

Electroanalytical analysis of guaifenesin on poly(acridine orange) modified glassy carbon electrode and its determination in pharmaceuticals and serum samples

2020 ◽  
Vol 23 ◽  
Author(s):  
Hasan Işik ◽  
Gökçe Öztürk ◽  
Fatma Ağin ◽  
Dilek Kul
Keyword(s):  
Human Serum ◽  
Acridine Orange ◽  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Supporting Electrolyte ◽  
Carbon Electrode ◽  
Modified Glassy Carbon Electrode ◽  
Serum Samples ◽  
Human Serum Samples

Background: Electroanalytical methods are very functional to detect drugs in pharmaceuticals (tablets, syrups, suppositories, creams and ointments) and biological samples. Objective: In this study, it is aimed to make selective, sensitive, simple, fast and low cost electrochemical analysis of expectorant drug guaifenesin in pharmaceuticals and serum samples. Method: Differential pulse adsorptive stripping voltammetric method for determination of guaifenesin on a poly(acridine orange) modified glassy carbon electrode has been developed. Glassy carbon electrode was modified with electropolymerization of acridine orange monomer for sensitive determination of guaifenesin. Guaifenesin provided highly reproducible and well-defined irreversible oxidation peaks at +1.125 V and +1.128 V (vs. Ag/AgCl) in the selected supporting electrolyte and human serum samples, respectively. Results: Under optimized conditions, linear response of peak current on the concentration of guaifenesin has been obtained in the ranges of 2.00×10-7 to 1.00×10-4 M in Britton Robinson buffer solution at pH 7.0 and 4.00×10-7 to 1.00×10-4 M in serum samples. The precision of the method was detected by intraday and inter-day repeatability studies in the supporting electrolyte and serum samples media. Conclusion: The analytical applicability of the proposed method exhibited satisfying determination results for guaifenesin from pharmaceutical dosage forms (syrup) and human serum samples without any pre-separation procedure.

scholarly journals DEVELOPMENT OF A SENSOR BY ELECTRO-POLYMERIZATION OF ERICHROME BLACK-T ON GLASSY CARBON ELECTRODE AND DETERMINATION OF AN ANTI-INFLAMMATORY DRUG DICLOFENAC

2018 ◽  
pp. 81-87
Author(s):  
Rohini M. Hanabaratti ◽  
Jayant I. Gowda ◽  
Suresh M. Tuwar
Keyword(s):  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Carbon Electrode ◽  
Pharmaceutical Dosage Form ◽  
Inflammatory Drug ◽  
Voltammetric Detection ◽  
Scan Rate ◽  
Electro Oxidation ◽  
Anti Inflammatory

Objective: The aim of this study was to develop a simple, reliable voltammetric method and its validation for determination of nonsteroidal anti-inflammatory drug diclofenac (DFC). Methods: The proposed method was based on electro-oxidation of DFC at poly (erichrome black T) modified glassy carbon electrode (PEBT/GCE) in 0.2 M phosphate buffer solution of pH 7.0. Cyclic voltammetry and differential pulse voltammetric techniques were employed to study electro-oxidation behavior. Under the optimal conditions, variations of EBT concentration, effect of pH, scan rate on the oxidation of DFC was studied. Results: A well-defined oxidation peak at about +0.59 V vs. standard calomel electrode was observed for voltammetric detection of DFC. pH effect shows the participation of an equal number of protons and electrons in the mechanism. The relation between a logarithm of peak current with the logarithm of scan rate indicated adsorption controlled behavior of electrode process. Concentration variations show a good linear response in the range 0.05 µM to 40 µM with the detection limit of 5.25 × 10-8 M. Conclusion: The prepared sensor exhibited good selectivity, sensitivity, and stability for the detection of DFC in the pharmaceutical dosage form and real samples. The developed method could possibly be adopted for pharmacokinetic studies and also in clinical and quality control laboratories where time and economy were important.

scholarly journals L-ARGININE DETERMINATION IN BIOLOGICALLY ACTIVE ADDITIVE BY VOLTAMMETRY

2020 ◽  
Vol 63 (7) ◽  
pp. 4-9
Author(s):  
Valentina A. Popova ◽  
Maria N. Ponomareva ◽  
Elena I. Korotkova
Keyword(s):  
Differential Pulse Voltammetry ◽  
Dietary Supplement ◽  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Differential Pulse ◽  
Biologically Active ◽  
Carbon Electrode ◽  
Scan Rate ◽  
Pulse Voltammetry

This article reports about the electrochemical determination of L-arginine on a glassy carbon electrode in a dietary supplement using anodic differential pulse voltammetry. The exponential depense of the peak current on the square root of the scan rate (I/v1/2), the shifts of the potential to the negative area and linear correlation between peak potential and logarithm of the scan rate (lg(v)) confirms that electrooxidation of L-arginine is an irreversible process. Moreover, the criteria of Semerano equals 0.4 may indicate the process of electrooxidation without adsorption. The effect of pH, accumulation potential, accumulation time and scan rate was tested on electrochemical behavior of L-arginine. Working conditions for L-arginine determination in model media are following: pH 13; Eacc 0.3 V, tacc 30 s; v = 60 mV s-1. A linear dependence of L-arginine electrooxidation current on its concentration was observed at the 0.9 V in the range between 1.0∙10-4 and 10∙10-4 mol l-1. The detection limit was 1.34∙10-6 mol l-1. A comparative determination of L-arginine in dietary supplement was carried out by the voltammetric method and capillary electrophoresis. Thus, the determination of L-arginine in a dietary supplement on a glassy carbon electrode in NaOH solution (pH 13) was successfully carried out using anodic differential pulse voltammetry. The proposed method does not require sample preparation and allows to quickly determine L-arginine in dietary supplement.

scholarly journals ELECTROCHEMICAL OXIDATION AND DETERMINATION OF AN ANTI-CANCER DRUG PEMETREXED DISODIUM

2017 ◽  
Vol 10 (3) ◽  
pp. 492
Author(s):  
Nagaraj P Shetti
Keyword(s):  
Electrochemical Oxidation ◽  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Phosphate Buffer Solution ◽  
Cancer Drug ◽  
Carbon Electrode ◽  
Experimental Conditions ◽  
Anti Cancer ◽  
Scan Rate ◽  
Pemetrexed Disodium

Abstract-The electrochemical oxidation of an anti-cancer drug Pemetrexed disodium has been investigated at glassy carbon electrode using voltammetric techniques. The dependence of current on potential, pH, concentrartion, scan rate, and excipients were investigated to optimize the experimental conditions. According to the liner relation between peak potential, peak current, scan rate and Pemetrexed disodium concentration, differential pulse voltammetric method for the quantitative determination in phosphate Buffer solution was developed. The linear response was obtained in the range of 10 µM to 0.75 µM with a detection limit of 0.19 µM. The electrochemical oxidation of mechanism of an anti-cancer drug Pemetrexed disodium was proposed. Keywords- Pemetrexed disodium, Cyclic Voltammetry, Electochemical Studies, Glassy carbon electrode

Determination of Cyanuric Acid by Electrochemical Cyclic Voltammetry Method Using CuGeO3 Nanowires as Modified Electrode Materials

2013 ◽  
Vol 4 (3) ◽  
Author(s):  
L. Z. Pei ◽  
Y. K. Xie ◽  
Y. Q. Pei ◽  
Z. Y. Cai ◽  
C. G. Fan
Keyword(s):  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Electrochemical Method ◽  
Electrode Materials ◽  
Cyanuric Acid ◽  
Cyclic Voltammogram ◽  
Carbon Electrode ◽  
Scan Rate ◽  
Cyclic Voltammetry Method

A simple electrochemical method for the determination of cyanuric acid (CA) has been developed based on a CuGeO3 nanowire modified glassy carbon electrode. The dense CuGeO3 nanowire film can be formed on the surface of the glassy carbon electrode. The roles of scan rate, CA concentration, and electrolytes with different pH values on the electrochemical responses of CA have also been analyzed. The intensities of two anodic peaks vary linearly with the increase of the scan rate from 25 to 200 mVs−1. The intensity of the electrochemical CV peak increases with the increase of the acidity of the electrolytes. The two anodic peak currents are linear with the CA concentration in the range of 0.005–2 mM. The linear correlation coefficient is 0.984 and 0.980 for the cyclic voltammogram peaks (cvp) cvp1 and cvp2, respectively. The detection limit is 4.3 μM and 2.1 μM for cvp1 and cvp2, respectively. The proposed electrochemical method is convenient and effective sensing of CA.

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