scholarly journals Bile Duct Adenoma with Oncocytic Features

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
E. J. Johannesen ◽  
Zihao Wu ◽  
Jason-Scott Holly
Keyword(s):  
Bile Duct ◽  
Bile Ducts ◽  
Colorectal Adenocarcinoma ◽  
Incidental Finding ◽  
Proliferation Index ◽  
Bile Duct Neoplasms ◽  
Mucin Production ◽  
Right Lobe ◽  
The Right ◽  
Bile Duct Adenoma

Bile duct adenomas are benign bile duct proliferations usually encountered as an incidental finding. Oncocytic bile duct neoplasms are rare and the majority are malignant. A 61-year-old male with a diagnosis of colorectal adenocarcinoma was undergoing surgery when a small white nodule was discovered on the surface of the right lobe of his liver. This lesion was composed of cytologically bland cells arranged in tightly packed glands. These cells were immunopositive for cytokeratin 7, negative for Hep Par 1, contained mucin, and had a Ki67 proliferation index of 8%. The morphology, immunophenotype, presence of mucin, and normal appearing bile ducts, as well as the increased Ki67 proliferation rate, were consistent with a bile duct adenoma with oxyphilic (oncocytic) change. Oncocytic tumors in the liver are rare; the first described in 1992. Only two bile duct adenomas with oncocytic change have been reported and neither of them had reported mucin production or the presence of normal appearing bile ducts within the lesion.

scholarly journals What Are the Precursor and Early Lesions of Peripheral Intrahepatic Cholangiocarcinoma?

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Yasuni Nakanuma ◽  
Akemi Tsutsui ◽  
Xiang Shan Ren ◽  
Kenichi Harada ◽  
Yasunori Sato ◽  
...  
Keyword(s):  
Bile Duct ◽  
Bile Ducts ◽  
Precursor Lesions ◽  
Intraductal Papillary Neoplasm ◽  
Combined Hepatocellular Cholangiocarcinoma ◽  
Biliary Adenofibroma ◽  
Bile Duct Lesions ◽  
Large Bile Duct ◽  
Papillary Neoplasm ◽  
Bile Duct Adenoma

Cholangiocarcinoma (CC) is divided into distal, perihilar, and intrahepatic CCs (ICCS), and are further subdivided into large bile duct ICC and peripheral ICC. In distal and perihilar CC and large duct ICC, biliary intraepithelial neoplasm (BilIN) and intraductal papillary neoplasm (IPN) have been proposed as precursor lesions. Peripheral ICC, bile duct adenoma (BDA), biliary adenofibroma (BAF), and von Meyenburg complexes (VMCs) are reportedly followed by development of ICCs. Herein, we surveyed these candidate precursor lesions in the background liver of 37 cases of peripheral ICC and controls (perihilar CC, 34 cases; hepatocellular carcinoma, 34 cases and combined hepatocellular cholangiocarcinoma, 25 cases). In the background liver of peripheral ICC, BDA and BAF were not found, but there were not infrequently foci of BDA-like lesions and atypical bile duct lesions involving small bile ducts (32.4% and 10.8%, resp.). VMCs were equally found in peripheral CCs and also control CCs. In conclusion, BDA, BAF, and VMCs are a possible precursor lesion of a minority of peripheral CCs, and BDA-like lesions and atypical bile duct lesions involving small bile ducts may also be related to the development of peripheral ICC. Further pathologic studies on these lesions are warranted for analysis of development of peripheral ICCs.

scholarly journals Comparative Anatomical, Ultrasonographical and Radiological studies of the biliary system of Rabbits and Domestic cats in Egypt

2019 ◽  
Author(s):  
R.T. Reem ◽  
M.A. Maher ◽  
H.E. Alaa ◽  
H.A. Farghali
Keyword(s):  
Bile Duct ◽  
Gall Bladder ◽  
Cystic Duct ◽  
Hepatic Duct ◽  
Human Model ◽  
Common Hepatic Duct ◽  
Domestic Cats ◽  
Left Hepatic Duct ◽  
Right Lobe ◽  
The Right

ABSTRACTUnder the prevailing overall Conditions of all veterinarians for the diagnosis of biliary diseases, application of surgical procedures and liver transplantation in Cats as carnivorous pet animal, and Rabbits as herbivorous pet animal and also as a human model in research. The present study was constructed on twelve native breeds of rabbits (Oryctolagus cuniculus) and eighteen adult domestic cats (Felis catus domesticus). We concluded that, in brief; the rabbit gall bladder was relatively small, fixed by several small hepato-cystic ducts to its fossa. The rabbit bile duct was formed commonly by the junction of the left hepatic duct and the cystic duct. The cystic duct was commonly fairly large, received the right hepatic duct that collected the right lobe in its route to enter the duodenum, the bile duct receives the branch of the caudate process of the caudate lobe. The present study revealed other four anatomic variations dealing with the shape and size of the feline native breed’s gall bladder from fundic duplication, bilobed, truncated fundus and distended rounded fundus. Commonly, the bile duct was formed by the triple convergence of the left and the right hepatic ducts with the cystic duct. However, in some exceptional cases a short common hepatic duct was formed. Sonographically, the normal gall bladder in rabbit appeared small, elongated with anechoic lumen bordered by right lobe laterally and quadrate lobe medially and has no visible wall, but in cat varied in conformation, bordered by the right medial lobe laterally and the quadrate lobe medially surrounded by echogenic wall.

scholarly journals Synchronous Thyrolipoma and Papillary Thyroid Carcinoma: A Rare but Significant Event

Diagnostics ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1334
Author(s):  
Mariya Kuk ◽  
Chu-Jen Kuo ◽  
Van-Hung Nguyen ◽  
Chien-Chin Chen
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Multinodular Goiter ◽  
Incidental Finding ◽  
Papillary Thyroid ◽  
Solitary Lesion ◽  
Neck Lymph Node ◽  
Thyroid Carcinomas ◽  
Right Lobe ◽  
The Right

The presence of adipocytes within thyroid glands is a rare finding seen in thyrolipoma, diffuse lipomatosis, or thyroid teratoma. Although some cases present with multinodular goiter or autoimmune thyroiditis, the exact cause has not yet been elucidated. Among reported cases, thyrolipomas mainly occur in females and usually present as a solitary lesion. However, a few reported cases had coexisting papillary thyroid carcinomas. Herein, we present a 51-year-old female with synchronous thyrolipoma (2.0 × 1.5 × 1.3 cm) and papillary thyroid carcinoma (0.7 × 0.6 × 0.6 cm) within the same thyroid lobe. She had diabetes mellitus and hypertension and complained of anterior neck enlargement and discomfort for three months. Thyroid sonography showed multiple hypoechoic nodules, one of which was heterogeneous and ill-defined. Fine needle aspirate cytology for the ill-defined nodule was suspicious for papillary thyroid carcinoma. She subsequently received radical thyroidectomy and neck lymph node dissection. Histopathologically, one thyrolipoma and one papillary thyroid carcinoma were identified in the right lobe of the thyroid gland without metastases of lymph nodes, while other nodules were multinodular goiter. Notably, thyrolipoma may not be simply an incidental finding but might coexist with thyroid carcinomas. A brief review of the pertinent literature of prior reports is also provided.

Identification Of Liver Fluke Eggs In Bile Duct Brush Cytology In An 82 Year Old Man With A Hepatic Mass: Report Of A Case

2020 ◽  
Vol 154 (Supplement_1) ◽  
pp. S92-S93
Author(s):  
F Chen ◽  
M Aguero-Rosenfeld ◽  
A Simsir ◽  
T C Brandler
Keyword(s):  
Bile Duct ◽  
Bile Ducts ◽  
Liver Fluke ◽  
Severe Disease ◽  
Clonorchis Sinensis ◽  
Brush Cytology ◽  
Abdominal Ct ◽  
Travel History ◽  
The Right ◽  
Human Infections

Abstract Introduction/Objective Clonorchis sinensis infects the liver, gallbladder, and bile ducts in humans. It is acquired via consumption of raw/undercooked fish, crabs, or crayfish in endemic areas. Though majority are asymptomatic, long lasting infections may cause severe disease. Without treatment, human infections may persist for the parasite lifespan (25–30 years). Diagnosis in cytology is challenging with a potentially acellular sample with miniscule eggs that can be overlooked as an artifact. Here we reported a rare case of liver fluke eggs diagnosed in bile duct brush cytology. Methods An 82 year old man who emigrated from China 20 years prior presented to the hospital with worsening jaundice for 2 weeks. Abdominal CT revealed a 4.8 x 2.9 cm central right hepatic lobe mass extending to the hilum, obstructing the bile ducts, resulting in severe intrahepatic ductal dilatation and stricture and focal occlusion of the right anterior portal vein. His CBC revealed eosinophilia. Bile duct brushing was submitted for cytology. Results ThinPrep and cell block showed oval-shaped parasite eggs measuring 10-24 µm. There was no other cellular matter. Eggs had a convex operculum resting on “shoulders” at the smaller end of the egg. At the opposite (abopercular) end, a small knob or hook-like protrusion was often visible. Wet mounts revealed visible miracidium inside the eggs. These findings were compatible with liver fluke eggs. Conclusion Cytologic microbiologic features of fluke eggs confirmed the findings. The most important features are the shape and size of the eggs; The seated operculum with its prominent “shoulders”, a small knob at the abopercular end, which can distinguish them from acellular artifact or a human cell. The cytologic and microbiologic features combined with the travel history and clinical presentation can aid in achieving the diagnosis.

scholarly journals Accessory sulci and segmentation on the surface of the liver: a clinical pitfall

2017 ◽  
Vol 5 (4) ◽  
pp. 1718
Author(s):  
Vishwajit Ravindra Deshmukh ◽  
Suryakanta Seth ◽  
Chetan Sahni
Keyword(s):  
Incidental Finding ◽  
Left Lobe ◽  
Right Lobe ◽  
Inferior Border ◽  
The Right

Diaphragmatic surface of liver is usually smooth but sometimes it is well marked by the sulci or indentations. Sometimes these sulci were so deep to be termed as fissures as they divide the lobe of liver into different segments. We report the case of accessory sulci along the Anterosuperior surface of the right lobe associated with Reidel’s lobe along the inferior border of the left lobe of same specimen. In another specimen, the sulci were so deep to be termed as fissures, which divides the caudate and quadrate lobe. Knowledge about the accessory sulci and lobes were necessary as they may appear as incidental finding during the laparoscopic examinations. Hence, it is very much promising to know about these sulci and lobes for hepatobiliary surgeons, anatomists and radiologists.

scholarly journals Iatrogenic injury of an aberrant right posterior sectoral bile duct

2011 ◽  
Vol 15 (3) ◽  
pp. 89-90
Author(s):  
John Cantrell
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Bile Duct ◽  
Bile Ducts ◽  
Anterior Abdominal Wall ◽  
Sinus Tract ◽  
The Other ◽  
Endoscopic Retrograde ◽  
History Of ◽  
The Right ◽  
Gallbladder Fossa

A 34-year-old woman presented with a history of a previous laparoscopic cholecystectomy, followed within a few days by a formal laparotomy for a suspected bile duct injury. Approximately one week after the laparotomy, she developed a sinus on the anterior abdominal wall that was draining bile. She was then referred to our institution for further management. The earlier surgery was done at another hospital, and these details were not clear. A CT scan, including a CT sinogram, was performed. The sinogram was done by inserting a catheter into the sinus and running in diluted contrast under gravity. CT images showed the sinus tract communicating with a collection in the gallbladder fossa, as well as contrast opacification of the segment 6 and 7 bile ducts. A week later, an endoscopic retrograde cholangiopancreatography (ERCP) examination was performed. This showed no filling of the right posterior sectoral ducts but normal opacification of the other ducts. These findings led to the diagnosis of an aberrant right posterior sectoral bile duct that was not identified prior to surgery and that was damaged at the time of laparoscopic cholecystectomy. This duct now drained into the gallbladder fossa, causing the collection and draining sinus.

scholarly journals On the anatomy and topography of the pancreas and the pancreatic duct in reindeer {Rangifer tarandus tarandus L)

Rangifer ◽  
1990 ◽  
Vol 10 (1) ◽  
pp. 25
Author(s):  
Sven Nikander
Keyword(s):  
Bile Duct ◽  
Pancreatic Duct ◽  
Rangifer Tarandus ◽  
Animal Species ◽  
Small Ruminants ◽  
Left Adrenal Gland ◽  
Complex Development ◽  
Right Lobe ◽  
The Common ◽  
The Right

<p>The complex development of the pancreas accounts for the differences in its morphology among various animal species. According to the present study, the anatomy of the pancreas in the reindeer is quite similar to that in small ruminants. It consists of two lobes, the left one (tail) extending in a ventrodorsal direction is in contact with the rumen, spleen, and the left adrenal gland. The right lobe (head) lies within the curve of the duodenum. Ducts analogous to the <em>ductus pancreaticus major</em> (Wirsungi) and <em>minor</em> (Santorini) join in a common pancreatic duct (<em>ductus pancreaticus</em>) which opens into the common bile duct (<em>ductus hepaticus communis</em>).</p><p>Haiman ja haimak&auml;yt&auml;v&auml;n anatomia ja topografia porolla.</p><p>Abstract in Finnish / Yhteenveto: Haiman kehittyminen on monimutkaista, mik&auml; aiheuttaa sen, ett&auml; haiman rakenne vaihtelee eri el&auml;inlajeilla. T&auml;m&auml;n tutkimuksen mukaan haiman rakenne porolla on hyvin samanlainen kuin pienill&auml; m&auml;rehtij&ouml;ill&auml;. Haimassa on kaksi lohkoa. Vasen lohko (h&auml;nt&auml;) on ventrodorsaalisessa suunnassa ja koskettaa p&ouml;t-si&auml;, pernaa ja vasenta lis&auml;munuaista. Oikea lohko (p&auml;&auml;) sijaitsee pohjukaissuolen mutkassa. Ductus pancreaticus majoria (Wirsungi) ja minoria (Santorini) vastaavat haimak&auml;yt&auml;v&auml;t yhtyv&auml;t muodostaen ductus pancreaticuk-sen, joka avautuu yhteiseen sappik&auml;yt&auml;v&auml;&auml;n (<em>ductus hepaticus communis</em>).</p><p>Pankreas och ductus pancreaticus anatomi och topografi hos ren.</p><p>Abstract in Swedish / Sammandrag: Pankreas ontogenes &auml;r invecklad, detta medf&ouml;r morfologiska variationer hos de olika djurarterna. Enligt denna undersokning p&aring;minner pankreas anatomi hos renen om de sm&aring; idisslarnas. Pankreas best&aring;r av tv&aring; lober. Den v&auml;nstra loben (svansen) stracker sig i ventrodorsal riktning och gr&auml;nsar till v&aring;mmen, mj&auml;lten och den v&auml;nstra binjuren. Den h&ouml;gra loben (huvudet) &aring;r i en slinga av tolvfingertarmen. Analoga g&aring;ngar till <em>ducuts pancreaticus major</em> (Wirsungi) och <em>minor</em> (Santorini) f&ouml;renas till ductus pancreaticus som mynnar ut i gallg&aring;ngen (<em>ductus hepaticus communis</em>).</p>

scholarly journals Iatrogenic Bile Duct Injury Associated with Anomalies of the Right Hepatic Sectoral Ducts: A Misunderstood and Underappreciated Problem

HPB Surgery ◽  
2009 ◽  
Vol 2009 ◽  
pp. 1-4 ◽  
Author(s):  
Nitin Babel ◽  
Sujit V. Sakpal ◽  
Prakash Paragi ◽  
Jason Wellen ◽  
Stephen Feldman ◽  
...  
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Bile Duct ◽  
Bile Duct Injury ◽  
Bile Ducts ◽  
Hepatic Duct ◽  
Open Cholecystectomy ◽  
Standard Of Care ◽  
Number Of Patients ◽  
The Right ◽  
Iatrogenic Bile Duct Injury

Although laparoscopic cholecystectomy (LC) has been widely accepted as the standard of care, it continues to have a higher complication rate than open cholecystectomy. Bile duct injury with LC has often been attributed to surgical inexperience, but it is also clear that aberrant bile ducts are present in a significant number of patients who sustain biliary injuries during these procedures. We present three cases of right sectoral hepatic duct injuries which occurred during LC and provide a discussion of the conditions which are likely to lead to these injuries, as part of a strategy to prevent them.

scholarly journals A case of hepatic intraductal papillary neoplasm of the bile duct

2021 ◽  
Author(s):  
Eisuke Mukaida ◽  
Akio Tamura ◽  
Kunihiro Yoshioka ◽  
Masao Nishiya ◽  
Tamotsu Sugai
Keyword(s):  
Magnetic Resonance Imaging ◽  
Bile Duct ◽  
Invasive Carcinoma ◽  
Pathological Findings ◽  
Resonance Imaging ◽  
Intraductal Papillary Neoplasm ◽  
History Of ◽  
Right Lobe ◽  
The Right ◽  
Papillary Neoplasm

In this report, we present a 57-year-old female with a history of mild alcoholic liver disease during a medical check-up. Abdominal computed tomography and magnetic resonance imaging showed a multicystic mass with a solid enhancing mural nodule in the right lobe of the liver. Subsequently, laparoscopic right liver lobectomy was performed and pathological findings revealed intraductal papillary neoplasm of the bile duct (IPNB) with an associated invasive carcinoma. IPNB is a relatively rare disease that should be considered in the differential diagnosis of hepatic cystic tumours. Our case report highlights the importance of capturing image findings of the IPNB as this disease has a high potential for malignancy.

scholarly journals Controversy in the Management of Cholangitis Secondary to Hydatid Daughter Cysts

HPB Surgery ◽  
1991 ◽  
Vol 4 (4) ◽  
pp. 321-329 ◽  
Author(s):  
Brian Davidson ◽  
T. Ezaki ◽  
Nagy Habib
Keyword(s):  
Bile Duct ◽  
Biliary Tree ◽  
Liver Cyst ◽  
Uneventful Recovery ◽  
Liver Cysts ◽  
Intrabiliary Rupture ◽  
Right Lobe ◽  
Upper Abdominal ◽  
The Right

A 36 year old Cypriot woman, resident in the U.K. since the age of three years, presented with pyrexia, jaundice and upper abdominal pain. On ultrasound examination the biliary tree was dilated, contained sludge and a cystic lesion was present in the liver. An endoscopic cholangiogram showed multiple filling defects in the bile duct which were not felt to be removable endoscopically and a nasobiliary drain was therefore inserted. On resolution of the cholangitis with drainage and antibiotics a laparotomy was performed. The right lobe of the liver was largely replaced by a multiloculated cyst and the bile duct contained multiple hydatid daughter cysts. A right hepatectomy was performed with t-tube drainage of the evacuated bile duct. She made an uneventful recovery and has had no problems on subsequent follow up. Histology confirmed an intrabiliary rupture of a hydatid liver cyst.Cholangitis secondary to daughter cysts is a rare but recognised complication of hydatid liver cysts. Management of hydatid liver cysts by formal resection is controversial but may be preferable in this situation.

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