scholarly journals Partial and Total Descemet’s Detachments in a Patient with Severe Terrien’s Marginal Degeneration and Juvenile Idiopathic Arthritis

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Amir Hossein Vejdani ◽  
Hamid Khakshoor ◽  
Michael V. McCaughey ◽  
Majid Moshirfar
Keyword(s):  
Juvenile Idiopathic Arthritis ◽  
Current Literature ◽  
Corneal Edema ◽  
Slit Lamp ◽  
Slit Lamp Examination ◽  
Intracameral Injection ◽  
History Of ◽  
Descemet’S Membrane ◽  
Complete Detachment ◽  
The Right

A 16-year-old female with juvenile idiopathic arthritis presented with a one-month history of decreasing vision and increasing corneal edema in her left eye. Slit-lamp examination, keratometric measurements, and OCT evaluation led to a diagnosis of Terrien’s marginal degeneration in both eyes along with a complete detachment of Descemet’s membrane in the left eye and partial detachment in the right eye. She was treated with an intracameral injection of air and then topical betamethasone and chloramphenicol which lead to the resolution of symptoms. We further examine the pathophysiology of this disease based on current literature.

scholarly journals External ophthalmomyiasis by sheep botfly – a report from Sirmaur hills

2020 ◽  
Vol 18 (1) ◽  
pp. 64-66
Author(s):  
Anubhav Chauhan ◽  
◽  
Neha Gautam ◽  
Keyword(s):  
Foreign Body ◽  
Oestrus Ovis ◽  
Human Tissues ◽  
Slit Lamp ◽  
Slit Lamp Examination ◽  
Topical Antibiotics ◽  
Body Sensation ◽  
History Of ◽  
Conjunctival Inflammation ◽  
The Right

Introduction. Myiasis is caused by larvae of flies infesting animal or human tissues and organs. Aim. In this report we present 2 cases of external ophthalmomyiasis by sheep botfly. Description of the cases. We report a case of two patients who presented with a history of foreign body sensation in the left and the right eye respectively. Slit lamp examination revealed larvae of Oestrus ovis (sheep botfly). In both cases, there was no contact history with sheep or goats. Signs of conjunctival inflammation and corneal involvement were absent in both cases. In most of the previous reports, corneal and conjunctival inflammation was present. Conclusion. Treatment for external ophthalmomyiasis is based on larvae removal and application of topical antibiotics and steroids.

scholarly journals Spontaneous Corneal Hydrops in a Patient with a Corneal Ulcer

2016 ◽  
Vol 7 (1) ◽  
pp. 49-53
Author(s):  
Hatim Batawi ◽  
Nikisha Kothari ◽  
Andrew Camp ◽  
Luis Bernhard ◽  
Carol L. Karp ◽  
...  
Keyword(s):  
Severe Pain ◽  
Corneal Ulcer ◽  
Treatment Options ◽  
Corneal Edema ◽  
Slit Lamp ◽  
Study Results ◽  
Mucous Discharge ◽  
History Of ◽  
Corneal Hydrops ◽  
The Right

Purpose: We report the case of a 77-year-old man with no history of keratoconus or other ectatic disorders who presented with corneal hydrops in the setting of a corneal ulcer. The risk factors, pathogenesis and treatment options of corneal hydrops are discussed. Method: This is an observational case report study. Results: A 77-year-old man presented with a 1-day history of severe pain, redness, mucous discharge and photophobia in the right eye. A slit-lamp examination of the right eye showed an area of focal corneal edema and protrusion. Within the area of edema and protrusion, there was an infiltrate with an overlying epithelial defect consistent with an infectious corneal ulcer. The Seidel test showed no leakage, so a clinical diagnosis of corneal hydrops associated with nonperforated corneal ulcer was made. With appropriate antibiotic treatment, the corneal ulcer and hydrops both resolved over a 1-month period. Conclusion: Corneal hydrops can occur in the setting of corneal infections.

Iridocorneal endothelial syndrome: Short report

2021 ◽  
Vol 2 (5) ◽  
Author(s):  
Benchakroun S ◽  
◽  
Taouri N ◽  
Tagmouti A ◽  
Cherkaoui LO ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Corneal Edema ◽  
Posterior Segment ◽  
Specular Microscopy ◽  
Short Report ◽  
Slit Lamp ◽  
Blurred Vision ◽  
Slit Lamp Examination ◽  
Iridocorneal Endothelial Syndrome ◽  
The Right

We report a case of a 42-year-old-woman, who presented to the ophthalmic consultation for decreased visual acuity complaints of blurred vision, altered pupillary shape since few months of her right eye. The clinical examination found a reduced visual acuity to counting fingers in the right eye and 20/20 in the left eye. intraocular pressures was 38 mm Hg OD and 14 mm Hg OS. Slit lamp examination of the right eye found: Corneal edema, iris atrophy with a deformation of the iris architecture and pupillary anomalies, with polycoria (Figure 1). The evaluation of the angle by gonioscopy found areas of broad synechiae anterior to Schwalbe’s line (Figure 2). While the examination of the left eye was normal (Figure 1B). The posterior segment examination was normal in both eyes. Specular microscopy confirmed the presence of unilateral endothelial pleomorphism and polymegathism. In our case of the retained diagnosis was iridocorneal endothelial syndrome

scholarly journals Successful Treatment of Post-Phacoemulsification Descemet’s Membrane Detachment Assessed by Anterior Segment Optical Coherence Tomography: A Case Report

2021 ◽  
pp. 611-615
Author(s):  
Ayaka Doi ◽  
Tadamichi Akagi ◽  
Akitaka Tsujikawa
Keyword(s):  
Optical Coherence Tomography ◽  
Sulfur Hexafluoride ◽  
Anterior Segment ◽  
Corneal Edema ◽  
Optical Coherence ◽  
Descemet’S Membrane Detachment ◽  
Intracameral Injection ◽  
Descemet's Membrane ◽  
Descemet’S Membrane ◽  
The Right

Descemet’s membrane detachment (DMD) is a rare but serious complication of phacoemulsification surgery. A small DMD may resolve spontaneously, but extensive DMD often requires intracameral injection of air, nonexpansile gases, or expansile gases. A 92-year-old man who underwent phacoemulsification and aspiration with intraocular lens placement in the right eye had significantly reduced visual acuity, with a hazy cornea after surgery. Anterior segment optical coherence tomography (AS-OCT) examination revealed extensive DMD throughout the cornea. He was treated with intracameral injection of 20% sulfur hexafluoride. As a result, the Descemet membrane was successfully reattached, and the corneal edema resolved. AS-OCT was helpful in confirming the presence and extent of DMD, provided useful information to determine the appropriate treatment, and was useful for monitoring DMD.

Late-onset malignant glaucoma

2020 ◽  
Vol 3 ◽  
pp. 1
Author(s):  
Ramiro José Daud ◽  
Horacio Freile ◽  
Mauricio Freile ◽  
Soledad Mariano
Keyword(s):  
Intraocular Pressure ◽  
Case Report ◽  
Acute Pain ◽  
Late Onset ◽  
Slit Lamp ◽  
Normal Range ◽  
Slit Lamp Examination ◽  
Complete Occlusion ◽  
Malignant Glaucoma ◽  
The Right

A case report on a 49-year-old female with diagnoses of ocular hypertension in her left eye (LE) treated with 250 mg/day acetazolamide for 2 years. During the slit-lamp examination, complete occlusion of both iridocorneal angles was detected. Intraocular pressure (IOP) was 10 and 35 mmHg in the right eye and LE, respectively. Phacotrabeculectomy was performed in the LE. After 1 month of the procedure, the patient developed a slowly progressive miopization from −1 to −3 diopters (D) the following months. Approximately 3 months after surgery, the patient developed an episode of acute pain, athalamia, and IOP 45 mmHg in her LE. Late-onset malignant glaucoma was suspected and the patient was treated with topical hypotensive and cycloplegic agent until a prompt vitrectomy was performed. Deepening of the anterior chamber and restoration of IOP to normal range was obtained after surgery.

scholarly journals Identification of a Novel Missense KRT12 Mutation in a Vietnamese Family with Meesmann Corneal Dystrophy

2020 ◽  
Vol 11 (1) ◽  
pp. 120-126
Author(s):  
Pham Ngoc Dong ◽  
Le Xuan Cung ◽  
Tran Khanh Sam ◽  
Do Thi Thuy Hang ◽  
Doug D. Chung ◽  
...  
Keyword(s):  
Sanger Sequencing ◽  
Novel Mutation ◽  
Family Members ◽  
Corneal Dystrophy ◽  
Slit Lamp ◽  
Slit Lamp Examination ◽  
Corneal Epithelial ◽  
Epithelial Phenotype ◽  
History Of ◽  
Characteristic Features

Meesmann epithelial corneal dystrophy (MECD) is a rare dominantly inherited disorder that is characterized by corneal epithelial microcysts and is associated with mutations in the keratin 3 (KRT3) and keratin 12 (KRT12) genes. In this study, we report a novel mutation in the KRT12 gene in a Vietnamese pedigree with MECD. Slit-lamp examination was performed on each of the 7 recruited members of a Vietnamese family to identify characteristic features of MECD. After informed consent was obtained from each individual, genomic DNA was isolated from saliva samples and screening of KRT3and KRT12 genes was performed by Sanger sequencing. The proband, a 31-year-old man, complained of a 1-year history of eye irritation and photophobia. Slit-lamp examination revealed intraepithelial microcysts involving only the corneal periphery in each eye with clear central corneas and no stromal or endothelial involvement. Three family members demonstrated similar intraepithelial microcysts, but with diffuse involvement, extended from limbus to limbus. Sanger sequencing of KRT3 (exon 7) and KRT12 (exons 1 and 6) in the proband revealed a novel heterozygous KRT12 variant (c.1273G>A [p.Glu425Lys]) that was present in the three affected family members but was absent in the three family members with clear corneas. This study is the first report of a Vietnamese family affected with MECD, associated with an atypical peripheral corneal epithelial phenotype in the proband and a novel mutation in KRT12.

Progressive multifocal leukoencephalopathy in a patient with occult hypogammaglobulinemia experiencing bilateral visual impairment

2021 ◽  
pp. 112067212199053
Author(s):  
Sameera Hettipathirannahelage ◽  
Sidath Wijetilleka ◽  
Hugh Jewsbury
Keyword(s):  
Progressive Multifocal Leukoencephalopathy ◽  
Visual Impairment ◽  
Demyelinating Disease ◽  
Parietal Lobe ◽  
Previous History ◽  
White Matter Lesions ◽  
Slit Lamp ◽  
Slit Lamp Examination ◽  
History Of ◽  
Ishihara Test

Introduction: Progressive multifocal leukoencephalopathy (PML) is a rare, lethal, demyelinating disease classically seen in profoundly immunosuppressed individuals. It is caused by intracerebral infection by John Cunningham polyomavirus (JCV). We report a rare case of PML in a man with presumed immunocompetence at presentation experiencing bilateral painless visual impairment. Case Description: A 60-year-old man with a 3-week history of bilateral painless visual impairment attended our ophthalmology department. Unusually, he navigated around the room well and was able to read 4 of 13 Ishihara test plates in spite of a best-corrected visual acuity of counting fingers at 1 m bilaterally. Slit lamp examination, routine blood tests and optical coherence tomography (OCT) of the maculae and discs were unremarkable. Diffuse hyperintense white matter lesions on T2-weighted magnetic resonance imaging of the brain and detection of JCV within the parietal lobe tissue obtained by biopsy confirmed PML. Additional investigations identified an underlying hypogammaglobulinaemia, which may have initiated PML. He received intravenous immunoglobulin but passed away 2 months after diagnosis. Conclusions: To our knowledge this case is one of only a handful worldwide to describe PML developing in a patient with presumed immunocompetence at presentation – there was no previous history of recurrent, chronic, or atypical infections. There has only been one other report of visual symptoms presenting as the primary complaint. The case illustrates the importance of ruling out organic, central nervous system pathology in patients presenting with visual loss and normal objective visual function tests such as slit lamp examination and OCT.

Ellipsoid layer restoration after Ozurdex® treatment in a patient with acute posterior multifocal placoid pigment epitheliopathy

2019 ◽  
pp. 112067211988359 ◽  
Author(s):  
Arnau Mora-Cantallops ◽  
M Dolores Pérez ◽  
Marcelino Revenga ◽  
Julio Jose González-López
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Acuity ◽  
Optical Coherence ◽  
Dexamethasone Implant ◽  
Slit Lamp ◽  
Slit Lamp Examination ◽  
Intravitreal Dexamethasone Implant ◽  
History Of ◽  
Intravitreal Dexamethasone ◽  
Consequent Improvement

An atypical case of acute posterior multifocal placoid pigment epitheliopathy with a clear reappearance of the ellipsoid layer of the retina after Ozurdex® intravitreal implantation is presented. A 51-year-old woman reported a 3-week history of left eye photopsia. On slit-lamp examination, yellowish placoid lesions were found on her left eye fundus. Ancillary tests were performed. The patient was diagnosed as a left eye acute posterior multifocal placoid pigment epitheliopathy, and observational approach was decided. Later, the condition started to progress in an ampiginous manner and a decrease of visual acuity caused by an increase in number and size of the lesions was observed. As the disease was progressing with the conservative, observational approach, and the macula was menaced, an intravitreal dexamethasone implant was injected in the left eye with a consequent improvement of the visual acuity and lesion stabilization. The ellipsoid layer, unidentifiable inside the placoid lesions in previous optical coherence tomography tests, reappeared after the treatment. Intravitreal dexamethasone implants can be used to stabilize acute posterior multifocal placoid pigment epitheliopathy lesions and help resolve the condition. Spectral domain optical coherence tomography can also be useful for monitoring these lesions, as the ellipsoid layer may reappear upon resolution.

scholarly journals Unilateral uveitis, cataract and retinal detachment following low-voltage electrical injury

2015 ◽  
Vol 3 ◽  
pp. 1-3 ◽  
Author(s):  
Rahmi Duman ◽  
Sadık Görkem Çevik ◽  
Ayşe Tüfekçi
Keyword(s):  
Retinal Detachment ◽  
Ultrasound Examination ◽  
Low Voltage ◽  
Rare Complication ◽  
Electrical Injury ◽  
Nuclear Cataract ◽  
Slit Lamp ◽  
Slit Lamp Examination ◽  
The Right ◽  
Granulomatous Anterior Uveitis

Abstract A 39-year-old woman presented with a gradual worsening of vision in the right eye 1 month after a low-voltage household electrical injury. A slit-lamp examination showed non-granulomatous anterior uveitis with nuclear cataract and an ultrasound examination also showed total retinal detachment. In this letter, we present a rare complication of electrical injury demonstrated as unilateral uveitis, cataract and retinal detachment in a 39-year-old woman.

scholarly journals Ocular Toxicity Secondary toAsclepias physocarpa: The Balloon Plant

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Susana Pina ◽  
Catarina Pedrosa ◽  
Cristina Santos ◽  
Bernardo Feijóo ◽  
Peter Pego ◽  
...  
Keyword(s):  
Corneal Edema ◽  
Specular Microscopy ◽  
Ocular Toxicity ◽  
Conjunctival Hyperemia ◽  
Blurred Vision ◽  
Ocular Irritation ◽  
Descemet's Membrane ◽  
Descemet’S Membrane ◽  
The Right

We report a case of a 65-year-old woman with symptoms of blurred vision and ocular irritation a few hours after accidental contact of the right eye withAsclepias physocarpamilky latex. Observation showed a diffuse conjunctival hyperemia and stromal corneal edema with Descemet’s membrane folds. Recovery was fast and apparently complete in less than one month. However, specular microscopy at 6-months follow-up showed an abnormal endothelial morphology as sequelae, suggesting this condition is not as innocuous as it has been suggested.

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