scholarly journals Tumour Calcification and Calciphylaxis in End-Stage Renal Disease

2014 ◽  
Vol 2014 ◽  
pp. 1-2
Author(s):  
Jia Di ◽  
Zhenxing Jiang ◽  
Min Yang
Keyword(s):  
Septic Shock ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Rare Case ◽  
Systemic Infection ◽  
Vascular Calcifications ◽  
All Cause Mortality ◽  
The Right ◽  
Stage Renal Disease ◽  
End Stage

Although soft tissue and vascular calcifications are common in CKD and progress as an independent risk factor of all-cause mortality, tumour calcification and calciphylaxis are uncommon in patients with end-stage renal disease (ESRD). Here, we discuss a rare case of a patient with tumour calcification complicated with calciphylaxis developed septic shock from infection. Our patient is a 57-year-old man in his late stage of renal disease who presented with a huge mass at the right hip and necrotic cutaneous ulcers on the lower legs followed by local and systemic infection and death due to septic shock.

scholarly journals Arterial stiffening and vascular calcifications in end‐stage renal disease

2000 ◽  
Vol 15 (7) ◽  
pp. 1014-1021 ◽  
Author(s):  
Alain P. Guérin ◽  
Gérard M. London ◽  
Sylvain J. Marchais ◽  
Fabien Metivier
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Vascular Calcifications ◽  
Arterial Stiffening ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Acute Kidney Injury in the Outpatient Setting Associates with Risk of End-Stage Renal Disease and Death in Patients with CKD

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Hung-Chieh Yeh ◽  
I.-Wen Ting ◽  
Han-Chun Huang ◽  
Hsiu-Yin Chiang ◽  
Chin-Chi Kuo
Keyword(s):  
Acute Kidney Injury ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Kidney Injury ◽  
Diagnostic Algorithm ◽  
Outpatient Setting ◽  
All Cause Mortality ◽  
Stage Renal Disease ◽  
End Stage ◽  
Overall Risk

AbstractCurrent acute kidney injury (AKI) diagnostic criteria are restricted to the inpatient setting. We proposed a new AKI diagnostic algorithm for the outpatient setting and evaluate whether outpatient AKI (AKIOPT) modifies the disease course among patients with chronic kidney disease (CKD) enrolled in the national predialysis registry. AKIOPT was detected when a 50% increase in serum creatinine level or 35% decline in eGFR was observed in the 180-day period prior to enrollment in the predialysis care program. Outcomes were progression to end-stage renal disease (ESRD) and all-cause mortality. Association analyses were performed using multiple Cox regression and coarsened exact matching (CEM) analysis. Among 6,046 patients, 31.5% (1,905 patients) had developed AKIOPT within the 180-day period before enrollment. The adjusted hazard ratios of the 1-year and overall risk of ESRD among patients with preceding AKIOPT compared with those without AKIOPT were 2.61 (95% CI: 2.15–3.18) and 1.97 (1.72–2.26), respectively. For 1-year and overall risk of all-cause mortality, patients with AKIOPT had respectively a 141% (95% CI: 89–209%) and 84% (56–117%) higher risk than those without AKIOPT. This statistical inference remained robust in CEM analysis. We also discovered a complete reversal in the eGFR slope before and after the AKIOPT from −10.61 ± 0.32 to 0.25 ± 0.30 mL/min/1.73 m2 per year; however, the loss of kidney function is not recovered. The new AKIOPT diagnostic algorithm provides prognostic insight in patients with CKD.

Fatal external bleeding from self-severed arterial dialysis tube: An unusual method of suicide

2019 ◽  
Vol 59 (4) ◽  
pp. 210-213
Author(s):  
Supawon Srettabunjong
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Multidisciplinary Approach ◽  
Early Screening ◽  
Haemodialysis Catheter ◽  
Appropriate Treatment ◽  
Treatment Of Depression ◽  
The Right ◽  
Stage Renal Disease ◽  
End Stage

A high risk of suicide has been observed in adults with end-stage renal disease who are undergoing haemodialysis. Since suicide is preventable, early screening, a prompt multidisciplinary approach and appropriate treatment of depression are critical and are recommended to treating physicians. Recently, the case of a woman with end-stage renal disease who had been undergoing haemodialysis was encountered. She died by suicide after self-severing the temporary haemodialysis catheter secured to the right side of her neck. This method of suicide is unusual and rare. This case not only underscores the association between haemodialysis and suicide in patients with end-stage renal disease but also raises awareness of the possibility of such deaths.

scholarly journals Interferon-Based Treatment of Hepatitis C Virus Infection Reduces All-Cause Mortality in Patients With End-Stage Renal Disease

Medicine ◽  
2015 ◽  
Vol 94 (47) ◽  
pp. e2113 ◽  
Author(s):  
Yueh-Han Hsu ◽  
Peir-Haur Hung ◽  
Chih-Hsin Muo ◽  
Wen-Chen Tsai ◽  
Chih-Cheng Hsu ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Hepatitis C Virus Infection ◽  
All Cause Mortality ◽  
Stage Renal Disease ◽  
End Stage

End-stage Renal Disease but Not Chronic Kidney Disease Is a Predictor for Worse Outcomes in Patients With Severe Sepsis and Septic Shock

CHEST Journal ◽  
2010 ◽  
Vol 138 (4) ◽  
pp. 387A ◽  
Author(s):  
Gagan Kumar ◽  
Ankit Sakhuja ◽  
Nilay Kumar ◽  
Abhishek Deshmukh ◽  
Emily McGinley ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Septic Shock ◽  
Severe Sepsis ◽  
Kidney Disease ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Stage Renal Disease ◽  
Sepsis And Septic Shock ◽  
End Stage

scholarly journals Interleukin 6 (rs1800795) and Pentraxin 3 (rs2305619) Polymorphisms - Association with Inflammation and All-Cause Mortality in End-stage-renal Disease Patients on Dialysis

2021 ◽  
Author(s):  
Susana Rocha ◽  
Maria João Valente ◽  
Susana Coimbra ◽  
Cristina Catarino ◽  
Petronila Rocha-Pereira ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Renal Disease ◽  
Interleukin 6 ◽  
End Stage Renal Disease ◽  
Pentraxin 3 ◽  
Allelic Frequencies ◽  
All Cause Mortality ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

Abstract Chronic inflammation plays an important role in the progression and outcome of chronic kidney disease (CKD). The inflammatory biomarkers interleukin-6 (IL6) and pentraxin 3 (PTX3) are enhanced in CKD patients and associated with progression of the disease and higher risk for cardiovascular events, the major cause of death in these patients. Our aim was to study how the polymorphisms of their encoding genes affect the inflammatory response and outcome of end-stage renal disease (ESRD) patients on dialysis. We analyzed two single nucleotide polymorphisms (SNP), the IL6 (rs1800795) polymorphism in the promoter region (-174G/C), and the PTX3 polymorphism in the intron 1 (+ 281A/G), in ESRD patients on dialysis and in heathy individuals. The allelic frequencies, genotype distribution and their association with the circulating levels of the inflammatory markers high sensitivity C-reactive protein (hsCRP), interleukin (IL6), growth differentiation factor 15 (GDF15) and PTX3, were determined in ESRD patients; events of death were recorded along one year to evaluate all-cause mortality and the association between inflammation and the studied polymorphisms. The allelic frequencies and genotyping distribution for IL6 and PTX3 in controls and ESRD patients were similar and in agreement with European reports. For the IL6 polymorphism, we found an association of the GG and CC genotype with higher IL6 levels; the CC genotype showed also high PTX3, hsCRP and GDF15 levels. For the PTX3 polymorphism, the AA genotype was linked to the highest values of hsCRP and IL6. The mortality rate after 1-year follow-up was 10.4%. The CC genotype (IL6 polymorphism), in deceased patients, was associated to increased levels of hsCRP, IL6 and PTX3, with low levels of GDF15 and with a highest mortality risk. The AA genotype for PTX3 polymorphism, in spite of the enhancement in inflammation, showed no significant impact on mortality. Our results show that the CC genotype of the IL6 polymorphism was associated with an enhanced inflammatory state and a poorer survival rate. Both IL6 and PTX3 polymorphisms seem to modulate the inflammatory response and, therefore, disease progression and outcome. Our data also highlights the importance of research on genetic variants that, although less frequent, may have significant biological value.

scholarly journals 7: IMPACT OF FLUID RESUSCITATION IN END-STAGE RENAL DISEASE PATIENTS WITH SEPTIC SHOCK

2021 ◽  
Vol 50 (1) ◽  
pp. 4-4
Author(s):  
Katie Chernoby ◽  
Allison Dzingle ◽  
Jessica Elefritz ◽  
Bruce Doepker ◽  
Andrea Nei ◽  
...  
Keyword(s):  
Septic Shock ◽  
Renal Disease ◽  
Fluid Resuscitation ◽  
End Stage Renal Disease ◽  
Stage Renal Disease ◽  
End Stage
Sign in / Sign up

Export Citation Format

Share Document