scholarly journals Design, Synthesis, and Characterization of Novel Thiol-Derivatized Ibuprofen Monolayer Protected Gold Clusters

2013 ◽  
Vol 2013 ◽  
pp. 1-8
Author(s):  
Kuan-Han Lee ◽  
Yu-Sheng Lin ◽  
Po-Jui Huang
Keyword(s):  
Nmr Spectroscopy ◽  
Gold Clusters ◽  
Hydroxyl Group ◽  
Synthesis And Characterization ◽  
Nmr Spectrum ◽  
Design Synthesis ◽  
H Nmr

A series of new thiol-derivatized ibuprofen monolayer protected gold clusters have been prepared by amidation of ibuprofen with alkyl alcohol or aminophenol affording the carboxamides, N-hydroxyalkyl amide2, and N-hydroxyphenyl amide6, which were then tosylated withp-toluenesulfonyl chloride at hydroxyl group to give3and7. Reactions of3and7with NaSH afforded the mercapto derivatives4and8. Conducting Brust’s reaction with a 3 : 1 mole ratio of thiolate ibuprofen/AuCl4-yielded polydisperse thiol-derivatized ibuprofen-MPCs5and9. All compounds have been identified by NMR, MS, UV, and IR spectroscopies. Compounds4and8and the MPCs5and9have been investigated by using the method of1H NMR spectroscopy. The broadening of the signals from 0.8 to 2.0 ppm in1H NMR spectrum of MPCs5and9confirmed the success of the conjugation of thiol-containing derivatives with nanogold cluster.

scholarly journals SYNTHESIS AND CHARACTERIZATION OF C-HEXYL CALIX[4]RESORCINARENA FROM RESORCINOL-HEPTANAL CONDENSATION

2016 ◽  
Vol 10 (1) ◽  
pp. 49
Author(s):  
Desi Suci Handayani ◽  
Zainal Arifin Almaqqomul Amin ◽  
Triana Kusumaningsih ◽  
Abu Masykur
Keyword(s):  
Melting Point ◽  
Nmr Spectroscopy ◽  
Structural Analysis ◽  
Chemical Shifts ◽  
Condensation Reaction ◽  
Wave Number ◽  
Synthesis And Characterization ◽  
H Nmr ◽  
Brown Powder

<p>Synthesis of  C-hexyl  calix[4]resorcinarene  through condensation reaction between resorcinol  and  heptanal  with  HCl  catalyst  has  been  investigated.  Synthesis  conducted  by the ratio of resorcinol: heptanal (1:1) using reflux for 6 hours in ethanol. Structural  analysis of  the  product  was  done  by  FTIR  and 1 H-NMR  spectroscopy,  while  the  characterization was  done  by  determining  melting  point.  The  product  was  golden  brown  powder  with  a yield 99.43%  and  melting point more than 300 °C.  Structural analysis with FTIR and 1 HNMR  known  vibration  and  signals  characteristic  of  calix[4]resorcinarena  group, the vibrations of the CH  bridge. Vibration of CH bridge appearance at wave number 1445 cm<sup>-1</sup> and 1456  cm<sup>-1</sup>, while signal of CH bridge appearance at chemical shifts from  4.17 to 4.21 ppm.</p>

SYNTHESIS AND CHARACTERIZATION OF C-HEXYL CALIX[4]RESORCINARENA FROM RESORCINOL-HEPTANAL CONDENSATION

2014 ◽  
Vol 10 (1) ◽  
pp. 49
Author(s):  
Desi Suci Handayani
Keyword(s):  
Melting Point ◽  
Nmr Spectroscopy ◽  
Structural Analysis ◽  
Chemical Shifts ◽  
Condensation Reaction ◽  
Wave Number ◽  
Synthesis And Characterization ◽  
H Nmr ◽  
Brown Powder

<p>Synthesis of C-hexyl calix[4]resorcinarene through condensation reaction between resorcinol and heptanal with HCl catalyst has been investigated. Synthesis conducted by the ratio of resorcinol: heptanal (1:1) using reflux for 6 hours in ethanol. Structural analysis of the product was done by FTIR and <sup>1</sup>H-NMR spectroscopy, while the characterization was done by determining melting point. The product was golden brown powder with a yield 99.43% and melting point more than 300 °C. Structural analysis with FTIR and <sup>1</sup>H-NMR known vibration and signals characteristic of calix[4]resorcinarena group,the vibrations of the CH bridge. Vibration of CH bridge appearance at wave number 1445 cm<sup>-1</sup> and 1456 cm<sup>-1</sup>, while signal of CH bridge appearance at chemical shifts from 4.17 to 4.21 ppm.</p>

Synthesis and Characterization of Polythiophenes Having Phosphonate Ester Groups

2011 ◽  
Vol 409 ◽  
pp. 502-507 ◽  
Author(s):  
Maki Katagiri ◽  
Masahiro Yoshizawa-Fujita ◽  
Yuko Takeoka ◽  
Masahiro Rikukawa
Keyword(s):  
Nmr Spectroscopy ◽  
Band Gap ◽  
Layered Structure ◽  
Oxidative Polymerization ◽  
Ester Group ◽  
Synthesis And Characterization ◽  
H Nmr ◽  
Self Organized ◽  
Polar Organic Solvents

Polythiophene derivatives containing a phosphonate ester group, poly [3-(3-diethyl-phosphonate) propoxythiophene] (PEPPT), were synthesized by Rieke and oxidative polymerization methods. These PEPPTs were soluble in polar organic solvents such as methanol, DMF, and chloroform. Thehead-to-tailratio of PEPPT (Rieke) was estimated to be 98 % by1H NMR spectroscopy, while that of PEPPT (Oxidative) was estimated to be 53 %. The maximum absorption peak of PEPPT (Rieke) was observed at 596 nm, which was 46 nm longer than that of PEPPT (Oxidative) in CHCl3solutions. This result suggests that the planarity of PEPPT (Rieke) is higher than that of PEPPT (Oxidative) due to the high regioregularity of the side chains. The estimated band gap of PEPPT was 1.60 eV for Rieke-synthesized derivatives. The XRD peak of PEPPT(Rieke) was observed at 5.14º (17.2 Å) and that of PEPPT (Oxidative) was not clearly observed, suggesting that PEPPT(Rieke) has self-organized properties to form a layered structure.

scholarly journals Synthesis and Characterization of Novel (E)-1-(Aylideneamino)-6-(4-Methoxyphenyl)-2-Oxo-4-(Trifluoromethyl)-1,2-Dihydropyridine-3-Carbonitrile Derivatives

2014 ◽  
Vol 30 ◽  
pp. 185-192 ◽  
Author(s):  
Hasmukh R. Khunt ◽  
Jayesh S. Babariya ◽  
Chandni D. Dedakiya ◽  
Charmi A. Maniar ◽  
Yogesh T. Naliapara
Keyword(s):  
Nmr Spectroscopy ◽  
Synthesis And Characterization ◽  
H Nmr

We have described simple facile method for the synthesis of Novel (E)-1-(aylideneamino)-6-(4-methoxyphenyl)-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile derivatives by using 1,3-diketone as synthon. All the synthesized compounds were characterized by IR, Mass and 1H NMR spectroscopy.

Synthesis and characterization of novel chiral derivatizing agents containing β-keto-anthracene adducts (KAAs) by 1H-NMR: aromatic influence and chiral alcohol absolute configuration determination

2019 ◽  
Vol 17 (3) ◽  
pp. 541-554
Author(s):  
Neeranuth Intakaew ◽  
Puracheth Rithchumpon ◽  
Chanatkran Prommin ◽  
Saranphong Yimklan ◽  
Nawee Kungwan ◽  
...  
Keyword(s):  
1H Nmr ◽  
Absolute Configuration ◽  
Synthesis And Characterization ◽  
Chiral Alcohols ◽  
Chiral Alcohol ◽  
Aromatic Rings ◽  
H Nmr ◽  
Chiral Derivatizing Agents

New chiral derivatizing agents and the effect of aromatic rings were investigated for absolute configuration of chiral alcohols via1H-NMR.

Synthesis and characterization of some polyimide-epoxy composites

e-Polymers ◽  
2011 ◽  
Vol 11 (1) ◽  
Author(s):  
Toheed Akhter ◽  
Humaira Masood Siddiqi ◽  
Zareen Akhter ◽  
M. Saeed Butt
Keyword(s):  
Thermal Behavior ◽  
Epoxy Resins ◽  
Analytical Techniques ◽  
Char Yield ◽  
Epoxy Composites ◽  
Hydroxyl Group ◽  
Synthesis And Characterization ◽  
Tetracarboxylic Acid ◽  
Epoxy Amine

AbstractComposites from some novel polyimide and commercial epoxy were prepared aiming to improve the thermal behavior of epoxy resins. Two diamines namely 4-4'-diamino-4''-hydroxytriphenyl methane (DHTM) and 4-4'- diaminotriphenyl methane (DTM) were synthesized by reacting aniline and aldehydes according to a reported method. The synthesized diamines were blended with commercially available epoxy 1, 4-butanedioldiglycidylether (BDDE) to synthesize model epoxy amine networks which were compared with polyimideepoxy composites. The polyimides were synthesized by reaction of these diamines with aromatic anhydride namely 3,3',4,4'-benzophenone tetracarboxylic acid dianhydride (BTDA). These synthesized polyimides were dispersed in epoxy diamine networks to prepare composites. All the monomers and composites were characterized by making use of various analytical techniques including FTIR, NMR, TGA, DSC and XRD. Presence of hydroxyl group in the diamine helped in better dispersion of polyimide leading to high Tg and high char yield at 600 °C.

scholarly journals Synthesis and characterization of different soybean oil-based polyols with fatty alcohol and aromatic alcohol

e-Polymers ◽  
2021 ◽  
Vol 21 (1) ◽  
pp. 491-499
Author(s):  
Fukai Yang ◽  
Hao Yu ◽  
Yuyuan Deng ◽  
Xinyu Xu
Keyword(s):  
Molecular Weight ◽  
Soybean Oil ◽  
Retention Time ◽  
Ring Opening ◽  
Isoamyl Alcohol ◽  
Synthesis And Characterization ◽  
Intermolecular Force ◽  
H Nmr ◽  
Epoxy Groups

Abstract In this article, five kinds of soybean oil-based polyols (polyol-E, polyol-P, polyol-I, polyol-B, and polyol-M) were prepared by ring-opening the epoxy groups in epoxidized soybean oil (ESO) with ethyl alcohol, 1-pentanol, isoamyl alcohol, p-tert-butylphenol, and 4-methoxyphenol in the presence of tetrafluoroboric acid as the catalyst. The SOPs were characterized by FTIR, 1H NMR, GPC, viscosity, and hydroxyl numbers. Compared with ESO, the retention time of SOPs is shortened, indicating that the molecular weight of SOPs is increased. The structure of different monomers can significantly affect the hydroxyl numbers of SOPs. Due to the large steric hindrance of isoamyl alcohol, p-hydroxyanisole, and p-tert-butylphenol, SOPs prepared by these three monomers often undergo further dehydration to ether reactions, which consumes the hydroxyl of polyols, thus forming dimers and multimers; therefore, the hydroxyl numbers are much lower than polyol-E and polyol-P. The viscosity of polyol-E and polyol-P is much lower than that of polyol-I, polyol-B, and polyol-M. A longer distance between the molecules and the smaller intermolecular force makes the SOPs dehydrate to ether again. This generates dimer or polymers and makes the viscosity of these SOPs larger, and the molecular weight greatly increases.

scholarly journals Design of an n-type low glass transition temperature radical polymer

2021 ◽  
Author(s):  
Teng Chi ◽  
Siddhartha Akkiraju ◽  
Zihao Liang ◽  
Ying Tan ◽  
Ho Joong Kim ◽  
...  
Keyword(s):  
Glass Transition ◽  
Transition Temperature ◽  
Glass Transition Temperature ◽  
Synthesis And Characterization ◽  
Design Synthesis

We document the design, synthesis, and characterization of the first low glass transition temperature, n-type (i.e., preferentially-reduced) radical polymer.

Design, Synthesis, and Characterization of Novel CXCR4 Antagonists Featuring Cyclic Amines

ChemMedChem ◽  
2020 ◽  
Vol 15 (13) ◽  
pp. 1150-1162
Author(s):  
Yu Lin ◽  
Zhanhui Li ◽  
Haikuo Ma ◽  
Yujie Wang ◽  
Xu Wang ◽  
...  
Keyword(s):  
Synthesis And Characterization ◽  
Design Synthesis ◽  
Cyclic Amines ◽  
Cxcr4 Antagonists
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