scholarly journals Successful Long-Term Use of Itraconazole for the Treatment ofAspergillusDiskospondylitis in a Dog

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Emiko Van Wie ◽  
Annie V. Chen ◽  
Stephanie A. Thomovsky ◽  
Russell L. Tucker
Keyword(s):  
Thoracolumbar Spine ◽  
Clinical Signs ◽  
Positive Culture ◽  
Spinal Pain ◽  
Intervertebral Disk ◽  
Resonance Imaging ◽  
German Shepherd ◽  
German Shepherd Dog ◽  
History Of

A 5-year-old spayed female German shepherd dog was admitted with a history of generalized stiffness. Neurologic examination revealed mild paraparesis with multifocal spinal pain. Spinal radiographs and magnetic resonance imaging revealed diskospondylitis at L6-7 and multiple sites throughout the thoracolumbar spine. Biopsy of the intervertebral disk at L6-7 revealed a positive culture forAspergillusspecies, and the dog was placed on itraconazole indefinitely. Clinical signs were significantly improved after two weeks of itraconazole. The dog was reevaluated 8 years later for unrelated reasons. No spinal pain was detected. Spinal radiographs revealed a fused L6-7 disk space and collapsed and sclerotic disk spaces at multiple sites. Itraconazole was tolerated by the dog with normal yearly liver enzyme values. To our knowledge, this is the first reported case of successful long-term use of itraconazole for the treatment ofAspergillusdiskospondylitis in a dog.

Successful treatment of regional enteritis in a dog

1995 ◽  
Vol 31 (2) ◽  
pp. 170-173 ◽  
Author(s):  
DC Lewis
Keyword(s):  
Successful Treatment ◽  
Regional Enteritis ◽  
German Shepherd ◽  
German Shepherd Dog ◽  
History Of ◽  
Granulomatous Enteritis

Regional enteritis was diagnosed in an 11-year-old, spayed female German shepherd dog with a history of intermittent vomiting and anorexia. Segmental, transmural granulomatous enteritis involved the pylorus, jejunum, and ileum. The jejunal lesions were excised. The remaining lesions completely resolved subsequent to long-term prednisone and sulfasalazine therapy.

Clinical, MRI and histopathological findings in a dog with distemper meningomyelitis

2020 ◽  
Vol 8 (3) ◽  
pp. e001173
Author(s):  
Alessandra Destri ◽  
Lluís Sánchez ◽  
Jennifer Stewart ◽  
Ruth Dennis
Keyword(s):  
Spinal Cord ◽  
Clinical Signs ◽  
Acute Onset ◽  
Mri Findings ◽  
German Shepherd ◽  
German Shepherd Dog ◽  
History Of ◽  
The Right ◽  
Clinical Mri ◽  
Severe Fever

A 14-month-old female entire German Shepherd dog presented with a five-day history of acute onset, progressive, non-ambulatory paraparesis, with lateralisation to the right. The neurolocalisation was to the L4-S1 spinal cord segments. MRI of the thoracic, lumbar and sacral spinal cord revealed multifocal, ill-defined, T2-weighted hyperintense, intramedullary lesions, which were moderately contrast-enhancing, becoming more defined and ovoid to nodular after injection of gadolinium-containing contrast medium. The lesions affected both white and grey matter and were lateralised mainly to the right side. PCR tests on blood and cerebrospinal fluid were positive for canine distemper virus (CDV). Despite intensive treatment, the dog developed myoclonus and severe fever and was humanely euthanased. Postmortem examination confirmed the presence of spinal cord lesions consistent with CDV. Distemper rarely presents with clinical signs of myelopathy exclusively and there is a scarcity of description of MRI findings of distemper meningomyelitis in the literature.

Intradural Dirofilariasis in a Dog with Chronic Cervical Pain

2017 ◽  
Vol 53 (1) ◽  
pp. 59-63
Author(s):  
Kathleen Ann Bonawandt ◽  
Jason M. Berg ◽  
Richard J. Joseph ◽  
Joseph D. Stefanacci
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cervical Spine ◽  
Magnetic Resonance ◽  
Spinal Pain ◽  
Resonance Imaging ◽  
Male Adult ◽  
Normal Limits ◽  
History Of ◽  
C2 Vertebra ◽  
Intradural Extramedullary

ABSTRACT A 7 yr old female spayed Yorkshire terrier was referred to the author's institute for a 5 mo history of recurrent cervical spinal pain. Neurologic examination did not reveal any deficits. Hematologic and serum analyses were within normal limits. Thoracic radiographs that incorporated the cervical spine did not show structural abnormalities. Magnetic resonance imaging of the cervical spine demonstrated a contrast enhancing, intradural extramedullary lesion at the level of the C2 vertebra. Hemilaminectomy was performed, during which a long, narrow nematode was visualized upon opening of the dura mater. The parasite was alive when removed during surgery, and the dog recovered with complete resolution of symptoms. The parasite was submitted and confirmed as a male adult Dirofilaria immitis. This is a novel case of an intradural D. immitis infection in the dog with a magnetic resonance imaging description of spinal D. immitis.

Diffuse annular fusiform adenocarcinoma in a dog

2000 ◽  
Vol 36 (2) ◽  
pp. 169-173 ◽  
Author(s):  
MR Prater ◽  
B Flatland ◽  
SJ Newman ◽  
DP Sponenberg ◽  
J Chao
Keyword(s):  
Large Bowel ◽  
Unusual Case ◽  
Clinical Signs ◽  
Postmortem Examination ◽  
Watery Diarrhea ◽  
Colonic Adenocarcinoma ◽  
German Shepherd ◽  
Regional Lymph Nodes ◽  
German Shepherd Dog ◽  
Neoplastic Lesion

Canine colonic intestinal adenocarcinoma typically presents as rectal polypoid or annular stenotic masses causing clinical signs consistent with large bowel disease. This report discusses an unusual case of intestinal adenocarcinoma in an 11-year-old, neutered male German shepherd dog presented for evaluation of anorexia, profuse watery diarrhea, and weight loss. In this dog, colonic adenocarcinoma diffusely infiltrated the entire large bowel and caused an annular fusiform lesion, as confirmed by endoscopic biopsies and postmortem examination. Other unique features included a paucity of desmoplasia associated with the neoplastic lesion and widespread metastasis to regional lymph nodes, lung, and prostate.

Atlantoaxial epidural abscess secondary to grass awn migration in a dog

2014 ◽  
Vol 27 (02) ◽  
pp. 155-158 ◽  
Author(s):  
U. Geissbühler ◽  
P. Karli ◽  
F. Forterre ◽  
E. Linon
Keyword(s):  
Magnetic Resonance Imaging ◽  
Case Report ◽  
Epidural Abscess ◽  
Cervical Vertebrae ◽  
Clinical Signs ◽  
Resonance Imaging ◽  
Mri Findings ◽  
History Of ◽  
Magnetic Resonance Imaging Mri ◽  
Grass Awn

SummaryA two-year-old female Lucerne Hound was presented with a one-week history of signs of progressive neck pain, inappetence, apathy, and an elevated rectal temperature. Findings of magnetic resonance imaging (MRI) were consistent with a foreign body abscess in the epidural space at the level of the first and second cervical vertebrae. A leftsided dorso-lateral atlantoaxial approach was performed, revealing an epidural abscess containing a grass awn. The clinical signs resolved within three days of surgery and the dog made a full recovery. This case report shows that grass awns can migrate to the atlantoaxial region in dogs and MRI findings lead to a suspicion of caudo-cranial migration within the spinal canal.

Review and retrospective analysis of degenerative lumbosacral stenosis in 156 dogs treated by dorsal laminectomy

2008 ◽  
Vol 21 (03) ◽  
pp. 285-293 ◽  
Author(s):  
N. Suwankong ◽  
G. Voorhout ◽  
A. de Boer ◽  
H. Hazewinkel ◽  
B. Meij
Keyword(s):  
Medical Records ◽  
Joint Angle ◽  
Facet Joint ◽  
Cauda Equina ◽  
Clinical Signs ◽  
Clinical Findings ◽  
Lumbar Pain ◽  
German Shepherd ◽  
Disc Protrusion ◽  
German Shepherd Dog

SummaryThe medical records of 156 dogs with degenerative lumbosacral stenosis (DLS) that underwent decompressive surgery were reviewed for signalment, history, clinical signs, imaging and surgical findings. The German Shepherd Dog (GSD) was most commonly affected (40/156, 25.6%). Pelvic limb lameness, caudal lumbar pain and pain evoked by lumbosacral pressure were the most frequent clinical findings. Radiography showed lumbosacral step formation in 78.8% (93/118) of the dogs which was associated with elongation of the sacral lamina in 18.6% (22/118). Compression of the cauda equina was diagnosed by imaging (epidurography, CT, or MRI) in 94.2% (147/156) of the dogs. Loss of the bright nucleus pulposus signal of the L7-S1 disc was found on T2-weighted MR images in 73.5% (25/34) of the dogs. The facet joint angle at L7-S1 was significantly smaller, and the tropism greater in GSD than in the other dog breeds. The smaller facet joint angle and higher incidence of tropism seen in the GSD may predispose this breed to DLS. Epidurography, CT, and MRI allow adequate visualization of cauda equina compression. During surgery, disc protrusion was found in 70.5% (110/156) of the dogs. Overall improvement after surgery was recorded in the medical records in 79.0% (83/105) of the dogs. Of the 38 owners that responded to questionnaires up to five years after surgery, 29 (76%) perceived an improvement.

scholarly journals Limber tail syndrome in German shepherd dog

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Ghazanfar Abbas ◽  
Muhammad Saqib ◽  
Mudassar Niaz Mughal ◽  
Asif Ali But ◽  
Ghulam Muhammad
Keyword(s):  
Cold Water ◽  
Clinical Signs ◽  
Acute Onset ◽  
Water Recovery ◽  
German Shepherd ◽  
German Shepherd Dog ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Freeze Water

A 3-year-old intact female German shepherd dog weighing 25 kg was evaluated for acute onset of staggering gait and flaccid (dropped) tail following immersion in freeze water. Clinical signs included staggering gait, aggressive behavior, postural pain and flaccid tail. Clinical signs progressed in severity for 2-3 hours following immersion in freeze water. The dog was treated using anti-inflammatory medication along with warm fomentation of the affected portion of the tail and complete rest. Dog uneventfully recovered on day 7 of initiation of treatment and no reoccurrence was observed during one month follow up period. Limber tail syndrome is an uncommonly reported condition in German shepherd dogs that should be considered when sudden staggering gait and dropped tail is observed after immersion in too cold water. Recovery is possible with anti-inflammatory drugs and rest.

scholarly journals Temporary remission of disseminated paecilomycosis in a German shepherd dog treated with ketoconazole : case report

2001 ◽  
Vol 72 (2) ◽  
Author(s):  
M.J. Booth ◽  
J.J. Van der Lugt ◽  
A. Van Heerden ◽  
J.A. Picard
Keyword(s):  
Case Report ◽  
Clinical Signs ◽  
Initial Diagnosis ◽  
Fungal Culture ◽  
German Shepherd ◽  
Laboratory Parameters ◽  
German Shepherd Dog ◽  
Fungal Hyphae ◽  
Carpal Joint

Disseminated mycosis caused by Paecilomyces varioti in a female German shepherd dog presented with chronic forelimb lameness is described. Radiographs of the swollen carpal joint revealed geographic lysis of the radial epiphysis. Diagnosis was based on cytological demonstration of fungal hyphae and chlamydiospores, as well as fungal culture of fluid obtained by arthrocentesis. Temporary remission was characterised by markedly improved clinical signs and laboratory parameters, following treatment with ketoconazole. The dog was euthanased 9 months after the initial diagnosis, following the diagnosis of multifocal discospondylitis. This appears to be the longest described period of temporary remission obtained with treatment in dogs with paecilomycosis. Clinical, clinicopathological and necropsy findings of this disease in another German shepherd dog are briefly described.

Mineralization of the transverse ligament of the atlas causing compressive radiculopathy

2016 ◽  
Vol 29 (03) ◽  
pp. 253-258 ◽  
Author(s):  
Leonard Hamilton ◽  
Colin Driver ◽  
Anna Tauro ◽  
Gary Campbell ◽  
Noel Fitzpatrick
Keyword(s):  
Magnetic Resonance Imaging ◽  
Clinical Signs ◽  
Transverse Ligament ◽  
Resonance Imaging ◽  
Cervical Nerve Root ◽  
Cervical Nerve ◽  
Pin Fixation ◽  
Indirect Decompression ◽  
History Of ◽  
Atlantoaxial Arthrodesis

Summary Objective: To describe a case of a Boxer dog with radiculopathy due to mineralization of the transverse ligament of the atlas and subsequent resorption and resolution of clinical signs after atlantoaxial arthrodesis and odontoidectomy. Case Report: A five-year-old neutered female Boxer dog was presented with a four-month history of cervical hyperaesthesia refractory to medical management. Neurological examination and magnetic resonance imaging indicated a diagnosis of radiculopathy due to cervical nerve root impingement by dystrophic mineralization of the transverse ligament of the atlas. Odontoidectomy was performed by a ventral approach and atlantoaxial arthrodesis was achieved with a ventral composite polymethylmethacrylate and pin fixation. Results: Atlantoaxial arthrodesis and progressive resorption of the mineralization following stabilization facilitated indirect decompression. The radioclinical diagnosis and response to arthrodesis was considered ana -logous to retro-odontoid pannus in the human. Clinical relevance: A clinical condition similar to retro-odontoid pannus may exist in the canine and may be amenable to atlantoaxial arthrodesis.

scholarly journals Tricuspid Dysplasia in Dogs

2013 ◽  
Vol 57 (1) ◽  
pp. 123-126 ◽  
Author(s):  
Urszula Pasławska ◽  
Agnieszka Noszczyk-Nowak ◽  
Adrian Janiszewski ◽  
Józef Nicpoń
Keyword(s):  
Clinical Symptoms ◽  
Heart Defects ◽  
Clinical Signs ◽  
The Body ◽  
German Shepherd ◽  
Ebstein Anomaly ◽  
German Shepherd Dog ◽  
Congenital Cardiac Disease ◽  
Cardiac Lesions ◽  
Estimate Prevalence

Abstract The aim of the study was to estimate prevalence of tricuspid dysplasia (TD) in dogs with respect to breed, age, sex, clinical signs, and echocardiographic findings and to compare this data with literature. TD was found in 15 dogs (6.5% of congenital cardiac disease) of 215 dogs with congenital heart defects. All dogs had right heart enlargement on thoracic radiographs, echocardiography, and electrocardiography. Doppler echocardiography revealed tricuspid valve regurgitation. Seven dogs presented no clinical symptoms to date. TD took the form of Ebstein anomaly in all Labrador Retrievers, one Boxer, and one German Shepherd dog. TD predominated in males (11 males vs. three females). The body weight of the affected dogs, with the exception of the Miniature Schnauzer, exceeded 20 kg. Two dogs (Boxer and Bull Terrier) had additional congenital cardiac lesions in the form of mitral valve dysplasia. The most affected breeds in the study were the Labrador Retriever and Boxer.

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