scholarly journals Predictors of Adherence to Antiretroviral Therapy among HIV/AIDS Patients in the Upper West Region of Ghana

ISRN AIDS ◽  
2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Christian Obirikorang ◽  
Peter Kuugemah Selleh ◽  
Jubilant Kwame Abledu ◽  
Chris Opoku Fofie
Keyword(s):  
Medication Adherence ◽  
Antiretroviral Therapy ◽  
Family Support ◽  
Positive Association ◽  
Cross Sectional Study ◽  
Aids Patients ◽  
Cross Sectional ◽  
Perceived Wellness ◽  
Effective Counseling ◽  
Hiv Aids

Background. The effectiveness of ART interventions is only realized in maximal levels of adherence. A near perfect adherence level of >95% is required for the effective suppression of HIV/AIDS virus. The main objective of this study was to identify the sociodemographic and socioeconomic factors that facilitate adherence to antiretroviral therapy among HIV/AIDS patients. Methods. This descriptive cross-sectional study was conducted between March and May 2013 at the Upper West Regional Hospital, Wa. A total of 201 confirmed HIV 1 seropositive subjects (mean age 36.6±9.9 years) receiving antiretroviral therapy were interviewed using a structured questionnaire. The collected data was analyzed using GraphPad Prism version 5. A P value of <0.05 was considered statistically significant for all statistical analyses. Results. Overall lifetime adherence was found to be 62.2% while medication adherence in the last six months, last three months, last month, and last week were 73.6%, 87.1%, 91.0%, and 86.0%, respectively. The study revealed a positive association between adherence to ART and immunological success, with nonadherence increasing the risk (OR (95% CI): 9.2 (3.2–26.9)) of immunological failure. Univariate logistic regression analysis of the data showed that other ailments and side effects of drug were negatively associated with adherence to ART whereas self-perceived wellness, family support, and regular followup were positively associated with adherence to ART. Conclusion. Regular attendance at followup and family support are vital factors for 100% lifetime medication adherence. Effective counseling sessions on adherence for patients on antiretroviral therapy are paramount for the realization of the purpose of antiretroviral therapy programmes in Ghana.

scholarly journals HIV/AIDS patients adherence to antiretroviral therapy and the impact of the use of psychoactive substances

2019 ◽  
Vol 11 (12) ◽  
pp. e640 ◽  
Author(s):  
Lucia Helena Gonzales Real ◽  
Karen Jansen ◽  
Fernanda Pedrotti Moreira ◽  
André Gonzales Real
Keyword(s):  
Antiretroviral Therapy ◽  
Cross Sectional Study ◽  
Social Classes ◽  
Psychoactive Substance ◽  
Psychoactive Substances ◽  
Aids Patients ◽  
Cross Sectional ◽  
Substance Involvement ◽  
The Impact ◽  
Hiv Aids

Objective: Describe the profile of the HIV/AIDS patients who use psychoactive substances; relate the use of psychoactive substances and Antiretroviral Therapy (ART) to non-adherence; and identify the main barriers for non-adherence. Methods: A cross-sectional study in a population of HIV/AIDS patients under ART prescription. Non-adherence to ART was considered when the patients presented a viral load higher than 40 copies per mL. The use of psychoactive substances was evaluated by Alcohol, Smoking and Substance Involvement Screening Test (ASSIST). Results: From 320 HIV/AIDS patients analyzed, 18.8% were not adhering to ART, 25.8% used alcohol, 21.7% smoked and 29.7% used some illicit psychoactive substance. The barriers were: high number of pills to be taken; fear that other people may know they are sick; difficulty of taking so many pills (if they do not feel sick); and they do not believe in the efficacy of the treatment (would rather try alternative treatments). Conclusion: Patients under higher risk are not white and young, from lower social classes, and use psychoactive substances. Strategies should focus on the promotion of adherence considering the barriers reported.

scholarly journals Pattern of Traditional Medicine Utilization among HIV/AIDS Patients on Antiretroviral Therapy at a University Hospital in Northwestern Ethiopia: A Cross-Sectional Study

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Abyot Endale Gurmu ◽  
Fitsum Sebsibe Teni ◽  
Wondmagegn Tamiru Tadesse
Keyword(s):  
Antiretroviral Therapy ◽  
Nigella Sativa ◽  
Cross Sectional Study ◽  
Traditional Healers ◽  
University Hospital ◽  
Aids Patients ◽  
Cross Sectional ◽  
Herbal Products ◽  
Specialized Hospital ◽  
Hiv Aids

The objective of this study was to assess traditional, complementary, and alternative medicine (TCAM) utilization pattern among HIV/AIDS patients on antiretroviral therapy at University of Gondar Comprehensive Specialized Hospital. Materials and Methods. Data on sociodemographic profile and clinical and TCAM utilization were collected using a structured, pretested questionnaire from April 01 to May 28, 2014, through interviews with patients. Data on CD4 count, HIV stage, and ART regimen were collected from patient records. Analysis was conducted descriptively using SPSS version 20. Results. Of the 300 participants, 43.7% reported using TCAM, with the largest proportion of them from religious institutions (churches/mosques) (41.22%), followed by home prepared (32.82%) and traditional healers (16.03%). The leading forms of TCAM used were spiritual and herbal therapies constituting 56.49% and 36.64% of the patients, respectively. The most frequently used herbal products included Nigella sativa (22.92%) and Moringa oleifera (20.83%). Most of the patients (73.30%) using TCAM reported improvement in their conditions. Conclusions. TCAM utilization among HIV/AIDS patients on ART was common and different sources and types were used alongside ART, with improvement reported by most. Further research is needed to identify CAM therapies which may be used as adjunct treatments among these patients.

scholarly journals Lipodystrophy induced by combination antiretroviral therapy in HIV/AIDS patients: A Belgrade cohort study

2014 ◽  
Vol 71 (8) ◽  
pp. 746-750 ◽  
Author(s):  
Gordana Dragovic ◽  
Dragana Danilovic ◽  
Aleksandra Dimic ◽  
Djordje Jevtovic
Keyword(s):  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Side Effect ◽  
Female Gender ◽  
Multivariate Regression Analysis ◽  
Cross Sectional Study ◽  
Aids Patients ◽  
Cross Sectional ◽  
Mortality And Morbidity ◽  
Hiv Aids

Background/Aim. Highly active antiretroviral therapy (HAART) has led to dramatic reductions in mortality and morbidity of HIV/AIDS-patients. Lipodystrophy, a syndrome including peripheral fat wasting and central obesity, is well-documented side effect of HAART. The aim of this study was to evaluate the incidence of lipodystrophy, and to determine its risk ratios in a HIV/AIDS cohort. Methods. This cross-sectional study included all antiretroviral-naive HIV/AIDS patients commencing HAART from October 1, 2001 to October 1, 2010, in the HIV/AIDS Center, Institute of Infectious and Tropical Diseases, Belgrade, Serbia. Univariate and stepwise multivariate logistic regression analyses were used to determine the odds ratios (OR) with the confidence interval (CI) of 95%, in order to establish the relative risk for lipodystrophy. The Kaplan-Meier-method was used to determine the probability of development lipodystrophy over time. All statistical analyses were performed using SPSS software version using 0.05 as a p-treshold for the significance. Results. This study included 840 HIV/AIDS patients, 608 women and 232 men, followed for 5.6 ? 2.8 years. The prevalence of lipodystrophy was 69.2%. Univariate and stepwise multivariate regression analysis identified that the female gender, hepatitis C coinfection, AIDS diagnosis prior to HAART initiation, nucleoside-reverse-transcriptase-inhibitors and proteaseinhibitors based regimens had a high risk for developing lipodystrophy in HIV/AIDS-patients (OR = 1.6, 95% CI = 1.1-3.49, p = 0.04; OR = 3.31, 95% CI = 1.4 - 3.8, p < 0.01; OR = 3.7, 95% CI = 1.7 - 6.1, p < 0.01; OR = 2.1, 95% CI = 1.7 - 3.3, p < 0.01; OR = 6.1, 95% CI = 4.1 - 9.7, p < 0.01, respectively). Conclusion. Despite much greater life expectancy of HIV/AIDSpatients, treatment-related toxicities still remain a major concern. Monitoring of lipodystrophy, as side effect of HAART, is particularly important.

scholarly journals Dukungan Keluarga terhadap Kepatuhan Minum Obat pada Pasien DM Tipe II

2020 ◽  
Vol 6 (1) ◽  
pp. 39-45
Author(s):  
Reny Sulistyowati ◽  
Agnes Dewi Astuti
Keyword(s):  
Medication Adherence ◽  
Family Support ◽  
Demographic Data ◽  
Cross Sectional Study ◽  
Information Support ◽  
Improve Medication Adherence ◽  
Cross Sectional ◽  
Study Approach ◽  
Type 2 Dm

The level of adherence usually decreases in patients with chronic conditions compared to acute conditions; this is related to the long-term nature of chronic disease due to the most rapid decrease in adherence after the first 6 months of therapy. The decline in compliance not only resulted in poor health outcomes but also had a significant impact on health costs. The purpose of this study was to determine family support for medication adherence in type 2 DM patients. This study used descriptive correlational using a cross-sectional study approach of 100 respondents. Patient demographic data and family support were obtained using a questionnaire while the level of compliance used Morisky Medication Adherence Scales. The results show that there is a relationship between family support and medication adherence in patients with type 2 diabetes, which is viewed from 4 dimensions: appreciation support, emotional support, information support, and instrumental support. Support from family can improve medication adherence in type 2 DM patients.

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