scholarly journals Role of Color Doppler Imaging in Early Diagnosis and Prediction of Progression in Glaucoma

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Fatima Jimenez-Aragon ◽  
Elena Garcia-Martin ◽  
Raquel Larrosa-Lopez ◽  
Jose M. Artigas-Martín ◽  
Pilar Seral-Moral ◽  
...  
Keyword(s):  
Risk Factors ◽  
Early Diagnosis ◽  
Color Doppler ◽  
Resistive Index ◽  
Color Doppler Imaging ◽  
Roc Curves ◽  
Doppler Imaging ◽  
Operating Characteristics ◽  
Diastolic Velocity ◽  
Retinal Artery

This longitudinal and prospective study analyzes the ability of orbital blood flow measured by color Doppler imaging (CDI) to predict glaucoma progression in patients with glaucoma risk factors. Patients with normal perimetry but having glaucoma risk factors and patients in the initial phase of glaucoma were prospectively included in the study and divided, after a five-year follow-up, into two groups: “Progression” and “No Progression” based on the changes in the Moorfields regression analysis (MRA) classification of Heidelberg retina tomograph (HRT). An orbital CDI was performed in all patients and the parameters obtained were correlated with changes in HRT. A logistic discrimination function (LDF) was calculated for ophthalmic artery (OA) and central retinal artery (CRA) parameters. Receiver operating characteristics curves (ROC) were used to assess the usefulness of LDFs to predict glaucomatous progression. A total of 71 eyes were included. End-diastolic velocity, time-averaged velocity, and resistive index in the OA and CRA were significantly different (P<0.05) between the Progression and No Progression groups. The area under the ROC curves calculated for both LDFs was of 0.695 (OA) and 0.624 (CRA). More studies are needed to evaluate the ability of CDI to perform early diagnosis and to predict progression in glaucoma in eyes.

RI in central retinal artery as assessed by CDI does not correspond to retinal vascular resistance

2001 ◽  
Vol 280 (4) ◽  
pp. H1442-H1447 ◽  
Author(s):  
Elzbieta Polska ◽  
Karl Kircher ◽  
Paulina Ehrlich ◽  
Pia V. Vecsei ◽  
Leopold Schmetterer
Keyword(s):  
Vascular Resistance ◽  
Color Doppler ◽  
Resistive Index ◽  
Color Doppler Imaging ◽  
Central Retinal Artery ◽  
Doppler Imaging ◽  
Mean Flow ◽  
Average Decrease ◽  
Ocular Perfusion ◽  
Retinal Artery

The aim of the present study was to investigate the association between ultrasound Doppler measurements of resistive index (RI) in the central retinal artery and retinal vascular resistance ( R) assessed with laser Doppler velocimetry, vessel size measurement, and calculation of ocular perfusion pressure (PP) in healthy subjects. An increase in vascular resistance was induced by inhalation of 100% O2. During hyperoxia no significant changes in PP were observed. Mean flow velocity in main retinal veins was reduced by −27.5 ± 2.0%. The average decrease in diameter was −11.5 ± 1.0%. R, which was calculated as the ratio of PP to flow rate, increased by 97.6 ± 7.7%. RI increased as well, but the effect was much smaller (6.6 ± 2.2%). In addition, a negative correlation was found between baseline values of R and RI ( r = −0.83). During hyperoxia R and RI were not associated. In conclusion, our data indicate that RI as assessed with color Doppler imaging in the central retinal artery is not an adequate measure of R.

scholarly journals Correlation of progression of diabetic retinopathy with the alterations in retrobulbar circulation

2013 ◽  
Vol 5 (2) ◽  
pp. 147-153 ◽  
Author(s):  
S Sood ◽  
Subina Narang ◽  
S Kocchhar ◽  
S Sarda ◽  
S Aggarwal ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Normal Population ◽  
Color Doppler ◽  
Case Series ◽  
Peak Systolic Velocity ◽  
Resistive Index ◽  
Doppler Imaging ◽  
Arterial Circulation ◽  
Diastolic Velocity ◽  
Group I

Introduction: Color Doppler Imaging (CDI) is used widely to study retrobulbar circulation. Objectives: To determine the association between progression of diabetic retinopathy (DR) and alterations in retrobulbar arterial circulation using CDI studies. Materials and methods: Prospective observational case series. It is single institutional study of 50eyes of nonproliferative diabetic retinopathy in 50 patients with type II diabetes mellitus. DR was graded according to ETDRS system. Retrobulbar circulation was studied in patients for Peak systolic velocity (PSV), End diastolic velocity (EDV) and Resistive index (RI) in Central retinal artery (CRA), Ophthalmic artery (OA) and Posterior ciliary artery (PCA) using CDI initially and reevaluated after 6 months or later for any change in retinopathy grade and arterial circulation parameters. The patients were grouped as Group I not showing progression of DR and Group II showing progression. The two groups were compared for any significant change in CDI parameters. Results: The baseline resistive indices were higher than normal population. There was significant increase in RI in PCA and CRA in all patients after 6 months. 14 patients (28%) showed progression of DR and 36 (72%) did not show progression of DR. There was no significant association with progression of retinopathy and CDI findings. (p=>0.05). Conclusion: The retrobulbar arterial circulation seems to be affected in all diabetics with DR. The changes appear to be progressive. The CDI findings in arterial circulation however lack predictive power for progression of diabetic retinopathy in non proliferative DR. Nepal J Ophthalmol 2013; 5(10): 147-153 DOI: http://dx.doi.org/10.3126/nepjoph.v5i2.8705

Evaluation of Resistive Index by Color Doppler Imaging of Orbital Arteries in Type II Diabetes Mellitus Patients with Microalbuminuria

Renal Failure ◽  
2012 ◽  
Vol 34 (6) ◽  
pp. 708-712 ◽  
Author(s):  
Taner Basturk ◽  
Ramazan Albayrak ◽  
Turgay Ulas ◽  
Mehmet Akcay ◽  
Abdulkadir Unsal ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type Ii Diabetes ◽  
Color Doppler ◽  
Resistive Index ◽  
Color Doppler Imaging ◽  
Type Ii Diabetes Mellitus ◽  
Doppler Imaging ◽  
Type Ii

Effect of Intravitreal Aflibercept on Central Retinal Arterial Blood Flow in Type 1 Retinopathy of Prematurity

2017 ◽  
Vol 27 (6) ◽  
pp. 751-755 ◽  
Author(s):  
Emine A. Sukgen ◽  
Gökhan Söker ◽  
Yusuf Koçluk ◽  
Bozkurt Gülek
Keyword(s):  
Blood Flow ◽  
Retinopathy Of Prematurity ◽  
Color Doppler ◽  
Color Doppler Imaging ◽  
Doppler Imaging ◽  
Intravitreal Aflibercept ◽  
Retinal Artery ◽  
The Mean ◽  
Type 1 Rop

Purpose To evaluate the blood flow changes of the central retinal artery measured with color Doppler imaging (CDI) in infants receiving intravitreal aflibercept (IVA) for treatment of type 1 retinopathy of prematurity (ROP). Methods Patients with type 1 ROP were assessed prospectively by CDI following IVA. Color Doppler imaging was used to measure the peak systolic velocity, end diastolic velocity (EDV), pulsatility index (PI), and resistivity index (RI) of the central retinal artery (CRA) before IVA injection and 1 hour, 1 week, and 1 month after injection. Results A total of 29 eyes of 15 infants were included in this study. The mean gestational age at birth was 28.62 ± 2.48 weeks and the mean birthweight was 1,198.62 ± 348.99 g. All treated eyes showed complete regression of ROP and peripheral retinal vascularization continued. Measurements of EDV-CRA, RI-CRA, and PI-CRA showed significant changes after IVA treatment. Conclusions This study showed that IVA is an effective treatment for type 1 ROP. After IVA treatment, vascular resistance increases, ocular blood flow decreases, and changes in hemodynamic parameters of CRA may remain for a month. Further studies are needed to evaluate the effect of anti-vascular endothelial growth factor agents on ocular hemodynamics in infants with ROP.

scholarly journals Comparison of Color Doppler Imaging Criteria for the Ophthalmic Artery and Central Retinal Artery in Infants with Retinopathy of Prematurity with and Without Plus Disease

2021 ◽  
Vol 18 (2) ◽  
Author(s):  
Marzieh Soleimani ◽  
Seyed Ehsan Ghetmiri ◽  
Mohammad Hossein Ahrar Yazdi
Keyword(s):  
Retinopathy Of Prematurity ◽  
Ophthalmic Artery ◽  
Color Doppler ◽  
Resistance Index ◽  
Color Doppler Imaging ◽  
Central Retinal Artery ◽  
Doppler Imaging ◽  
Significant Difference ◽  
Retinal Artery ◽  
The Mean

Background: Color Doppler imaging (CDI) is a non-aggressive and safe technique for the clinical management of retinal diseases. Recently, the number of infants with retinopathy of prematurity (ROP) has increased due to the incidence of premature births. Objectives: This study aimed to compare the CDI criteria for the ophthalmic artery (OA) and central retinal artery (CRA) in ROP infants with and without plus disease. Patients and Methods: In this case-control study, 42 premature infants (21 infants with plus disease and 21 infants without plus disease) underwent CDI. The arterial CDI parameters, including end-diastolic velocity (EDV), pulsatility index (PI), resistance index (RI), and peak systolic velocity (PSV), were measured in these patients. After collecting the data, t-test and chi-square tests were used for data analysis. P < 0.05 was considered to be statistically significant. Results: The mean EDV of CRA in patients with and without plus disease was 4.35 ± 1.00 and 5.27 ± 1.02 cm/sec, respectively (P = 0.005). The mean PSV of CRA in patients with and without plus disease was 15.65 ± 3.35 and 18.39 ± 4.39 cm/sec, respectively (P = 0.029). However, no significant difference was found between the two groups in terms of PSV or EDV of OA (P > 0.05). Also, no significant difference was observed between the two groups considering the RI and PI of CRA and OA (P > 0.05). Conclusion: According to the findings of this study, CDI criteria, such as EDV and PSV of CRA, were significantly lower in infants with plus disease as compared to those without plus disease. Since detecting the early stages of plus disease is a challenge for ophthalmologists, assessment of these criteria can be helpful for differentiation of these two subgroups of patients. However, further studies with a larger sample size are needed to determine the cutoff value.

scholarly journals Evaluation of resistive index using color Doppler imaging of orbital arteries in geriatric patients with hypertension

2014 ◽  
Vol 62 (6) ◽  
pp. 671 ◽  
Author(s):  
Ali Akal ◽  
Tugba Goncu ◽  
Ekrem Karakas ◽  
FatimaNurefsan Boyaci ◽  
Abdulgafur Bata ◽  
...  
Keyword(s):  
Geriatric Patients ◽  
Color Doppler ◽  
Resistive Index ◽  
Color Doppler Imaging ◽  
Doppler Imaging

scholarly journals Short-Term Effects of Acupuncture on Open-Angle Glaucoma in Retrobulbar Circulation: Additional Therapy to Standard Medication

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Shin Takayama ◽  
Takashi Seki ◽  
Toru Nakazawa ◽  
Naoko Aizawa ◽  
Seri Takahashi ◽  
...  
Keyword(s):  
Open Angle Glaucoma ◽  
Color Doppler ◽  
Resistive Index ◽  
Color Doppler Imaging ◽  
Doppler Imaging ◽  
Open Angle ◽  
Before And After ◽  
Standard Medication ◽  
Ciliary Artery ◽  
Additional Therapy

Background. The relation between glaucoma and retrobulbar circulation in the prognosis has been indicated.Purpose. To investigate the effects of acupuncture on retrobulbar circulation in open-angle glaucoma (OAG) patients.Methods. Eleven OAG patients (20 eyes with OAG) who were treated by topical antiglaucoma medications for at least 3 months were enrolled. Acupuncture was performed once at acupoints BL2, M-HN9, ST2, ST36, SP6, KI3, LR3, GB20, BL18, and BL23 bilaterally. Retrobulbar circulation was measured with color Doppler imaging, and intraocular pressure (IOP) was also measured at rest and one hour after rest or before and after acupuncture.Results. TheΔvalue of the resistive index in the short posterior ciliary artery (P<.01) and theΔvalue of IOP (P<.01) were decreased significantly by acupuncture compared with no acupuncture treatment.Conclusions. Acupuncture can improve the retrobulbar circulation and IOP, which may indicate the efficacy of acupuncture for OAG.

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