scholarly journals Multicentric Giant Cell Tumor of Bone: Synchronous and Metachronous Presentation

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Reiner Wirbel ◽  
Frank Blümler ◽  
Dirk Lommel ◽  
Guido Syré ◽  
Veit Krenn

A 27-year-old man treated 2.5 years ago for synchronous multicentric giant cell tumor of bone located at the right proximal humerus and the right 5th finger presented now with complaints of pain in his right hip and wrist of two-month duration. Radiology and magnetic resonance revealed multicentric giant cell tumor lesions of the right proximal femur, the left ileum, the right distal radius, and the left distal tibia. The patient has an eighteen-year history of a healed osteosarcoma of the right tibia that was treated with chemotherapy, resection, and allograft reconstruction. A literature review establishes this as the first reported case of a patient with synchronous and metachronous multicentric giant cell tumor who also has a history of osteosarcoma.

2021 ◽  
pp. 014556132110029
Author(s):  
Shiori Suzuki ◽  
Hiroshige Tsuda ◽  
Nobuyuki Bandoh ◽  
Takashi Goto ◽  
Akihiro Uemura ◽  
...  

A 74-year-old Japanese woman with a 1-year history of right preauricular pain and a 2-month history of bleeding from the right ear was admitted to our department. Tumor was observed in the anterior wall in the right external auditory canal. Bony swelling of the right preauricular area was palpated. Computed tomography revealed an ill-defined, osteogenic tumor around the mandibular condyle with a destructive bony lesion involving the temporal bone. Magnetic resonance imaging revealed a 2.0 × 1.5 × 1.3-cm solid tumor around the mandibular condyle, exhibiting a low-intensity signal on T1-weighted imaging and an isointense central area surrounded by low-signal intensity on T2-weighted imaging. Histological examination of biopsy specimens revealed diffuse-type tenosynovial giant cell tumor (D-TGCT). After the feeding arteries for the tumor were embolized, the patient underwent surgery with combined temporal craniotomy and mandibular condylectomy. The soft and cystic tumor with calcification located in the extradural space was totally resected along with the mandibular condyle. No facial paralysis or recurrence was evident as of 6 months postoperatively. To date, only 23 cases of D-TGCT arising in the temporomandibular joint (TMJ) with ear involvement have been reported since 2011. We report successful resection of a rare case of D-TGCT arising in the TMJ.


2017 ◽  
Vol 43 (1) ◽  
Author(s):  
Samvel Bardakhchyan ◽  
Leo Kager ◽  
Samvel Danielyan ◽  
Armen Avagyan ◽  
Nerses Karamyan ◽  
...  

Cureus ◽  
2021 ◽  
Author(s):  
Cihan Kadipasaoglu ◽  
Andrew Wahba ◽  
Meenakshi B Bhattacharjee ◽  
Branko Cuglievan ◽  
Stephen A Fletcher

Author(s):  
Eliandro de Souza Freitas ◽  
Francisco Amadis Batista Ferreira ◽  
Brendo Vinícius Rodrigues Louredo ◽  
Milena Gomes Melo Leite ◽  
José da Cruz Luna Neto ◽  
...  

Giant Cell Tumor of Bone is an uncommon aggressive benign neoplasm that frequently affecting the epiphysis of long bones especially around the knee. This is a singular rare case of GCTB in the right maxillary sinus implicated in a process coincidentally or casually with another type of lesion primarily developed.


2005 ◽  
Vol 84 (7) ◽  
pp. 432-434 ◽  
Author(s):  
Marcus M. Lessa ◽  
Flavio A. Sakae ◽  
Robinson K. Tsuji ◽  
Bernardo C. Araújo Filho ◽  
Richard L. Voegels ◽  
...  

Brown tumor, an uncommon focal giant-cell lesion, arises as a direct result of the effect of parathyroid hormone on bone tissue in patients with hyperparathyroidism. The initial treatment involves the correction of hyperparathyroidism, which usually leads to tumor regression. We report a case of brown tumor of the right nasal fossa in a 71-year-old woman. The tumor had caused nasal obstruction and epistaxis. Laboratory evaluation revealed that the patient had primary hyperparathyroidism. Anatomicopathologic investigation revealed the presence of a giant-cell tumor. We performed a partial parathyroidectomy, but the tumor in the right nasal fossa failed to regress. One year later, we performed surgical resection of the lesion. The patient recovered uneventfully, and she remained asymptomatic and recurrence-free at the 1-year follow-up. Facial lesions with histologic features of a giant-cell tumor should be evaluated from a systemic standpoint. Hyperparathyroidism should always be investigated by laboratory tests because most affected patients are asymptomatic. Surgical resection of a brown tumor should be considered if the mass does not regress after correction of the inciting hyperparathyroidism or if the patient is highly symptomatic.


2008 ◽  
Vol 204 (8) ◽  
pp. 583-588 ◽  
Author(s):  
Rikuo Machinami ◽  
Kazunori Nishida ◽  
Tsuyoshi Ishida ◽  
Seiichi Matsumoto ◽  
Kouji Kuroda ◽  
...  

2016 ◽  
Vol 32 (5) ◽  
pp. 873-876 ◽  
Author(s):  
Loic Sigwalt ◽  
Emeline Bourgeois ◽  
Ahmad Eid ◽  
Chantal Durand ◽  
Jacques Griffet ◽  
...  

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