scholarly journals Effects of Low Level Laser Therapy on Ovalbumin-Induced Mouse Model of Allergic Rhinitis

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Binhye Choi ◽  
Mun Seog Chang ◽  
Ha Young Kim ◽  
Jae-Woo Park ◽  
Bongha Ryu ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Laser Irradiation ◽  
Laser Therapy ◽  
Low Dose ◽  
Low Level Laser Therapy ◽  
High Dose ◽  
Low Level ◽  
Low Level Laser ◽  
Dose Irradiation ◽  
Level Laser

Introduction. This study was designed to investigate the effects of low level laser therapy (LLLT) on experimental allergic rhinitis (AR) models induced by ovalbumin.Materials and Methods. AR was induced by 1% ovalbumin in mice. Twenty-four mice were divided into 4 groups: normal, control, low, and high dose irradiation. Low and high dose LLLT were irradiated once a day for 7 days. Total IgE, cytokines concentrations (IL-4 and IFN-γ), and thymus and activation regulated chemokine (TARC) were measured. Histological changes in the nasal mucosal tissue by laser irradiation were examined.Results. LLLT significantly inhibited total IgE, IL-4, and TARC expression in ovalbumin-induced mice at low dose irradiation. The protein expression level of IL-4 in spleen was inhibited in low dose irradiation significantly. IL-4 expression in EL-4 cells was inhibited in a dose dependent manner. Histological damages of the epithelium in the nasal septum were improved by laser irradiation with marked improvement at low dose irradiation.Conclusion. These results suggest that LLLT might serve as a new therapeutic tool in the treatment of AR with more effectiveness at low dose irradiation. To determine the optimal dose of laser irradiation and action mechanisms of laser therapy, further studies will be needed.

Abstract 423: Low Level Laser Therapy Stimulates Hypoxia-Inducible Factor Expression and Increases MicroRNA 210 Content after Rat Myocardial Infarction

Hypertension ◽  
2014 ◽  
Vol 64 (suppl_1) ◽  
Author(s):  
Jose A Silva ◽  
Regiane S Feliciano ◽  
Andrey J Serra ◽  
Martha T Manchini ◽  
Eduardo T Santana ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Laser Irradiation ◽  
Laser Therapy ◽  
Systolic Dysfunction ◽  
Hypoxia Inducible Factor ◽  
Micro Rna ◽  
Low Level Laser Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

Low-level laser therapy (LLLT) has been used as an anti-inflammatory alternative treatment in several disease conditions, even when inflammation is a secondary consequence, such as in myocardial infarction (MI). LLLT treatment effectively reduces MI size and attenuates the systolic dysfunction after MI. However, the mechanism by which LLLT is able to protect the remaining myocardium remains unclear. Here, we tested the hypothesis that LLLT might reduce the hypoxia effects generated by MI. To achieve this purpose, we evaluated, after laser irradiation, the modulation of hypoxia-inducible factor (HIF) and microRNA 210 expressions, which are consistently stimulated under hypoxic conditions. We observed that HIF content presented an up-regulation after MI, however, a significant augmented HIF expression was observed after LLLT. Accordingly, micro-RNA 210 expression in the MI remote area increased even further after laser irradiation. Our data suggest that LLLT stimulates HIF expression pathway, increasing hypoxia-induced microRNA 210 content after MI, therefore, highlighting a possible cardioprotective role of LLLT.

Variability of high-dose melphalan exposure on oral mucositis in patients undergoing prophylactic low-level laser therapy

2017 ◽  
Vol 32 (5) ◽  
pp. 1089-1095 ◽  
Author(s):  
Gustavo Henrique Rodrigues ◽  
Graziella Chagas Jaguar ◽  
Fabio Abreu Alves ◽  
Andre Guollo ◽  
Vanessa Oliveira Camandoni ◽  
...  
Keyword(s):  
Laser Therapy ◽  
Oral Mucositis ◽  
Low Level Laser Therapy ◽  
High Dose ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser ◽  
High Dose Melphalan

Assessment of healing of dental implant surgical site following Low-Level Laser Therapy using Bio-Clinical parameters: An Exploratory Study

2020 ◽  
Author(s):  
VARSHA PALLED ◽  
DR. JITENDRA RAO ◽  
DR. RAGHUWAR DAYAL SINGH ◽  
DR. SHUCHI TRIPATHI ◽  
DR. KALPANA SINGH ◽  
...  
Keyword(s):  
Laser Therapy ◽  
Test Group ◽  
Low Level Laser Therapy ◽  
Control Group ◽  
Clinical Parameters ◽  
Implant Stability ◽  
Low Level ◽  
Implant Stability Quotient ◽  
Low Level Laser ◽  
Level Laser

The purpose of this study was to evaluate whether Low-Level Laser Therapy (LLLT) improves the healing of the implant surgical site with clinical and biochemical parameters.Thirty patients with an edentulous space spanning a single tooth were selected. The patients were randomly allocated to two groups - the control group and the test group. The test group received laser energy at a power of 2J/cm 2 with a total of 4-6J energy over each implant. Clinical parameters (Implant Stability Quotient, probing index, modified sulcus bleeding index)and osteoprotegerin (OPG) were assessed at baseline and follow-up intervals (2 weeks, 6 weeks, and 3 months).The test group showed significantly higher implant stability quotient compared to thecontrol group at 2 weeks(57.93±3.95 and 35.67±3.08; p<0.01) and 3months(58.86±3.75 and 67.06±3.78; p<0.01). A significant rise in OPG levels of the test group(686.30±125.36pg/ml at baseline and 784.25±108.30pg/ml at 3months;p<0.01) was seen contrary to significant decline in the control group (839.50±249.08pg/ml at baseline,415.30±78.39pg/ml at 3months;p<0.01). Within the limitations of the study, the study suggests that the healing of peri-implant hard and soft tissues may be enhanced with the use of LLLT as an explicit modality during the post-operative period.

Low-level laser therapy for neurosensory recovery after sagittal ramus osteotomy

2020 ◽  
Vol 69 (3) ◽  
Author(s):  
Paulo Esteves Pinto Faria ◽  
Astrid Temprano ◽  
Fábio Piva ◽  
Eduardo Sant'ana ◽  
Dênis Pimenta
Keyword(s):  
Laser Therapy ◽  
Low Level Laser Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser
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