scholarly journals Optimal Control Strategy for SEIR with Latent Period and a Saturated Incidence Rate

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Abta Abdelhadi ◽  
Laarabi Hassan

We propose an SEIR epidemic model with latent period and a modified saturated incidence rate. This work investigates the fundamental role of the vaccination strategies to reduce the number of susceptible, exposed, and infected individuals and increase the number of recovered individuals. The existence of the optimal control of the nonlinear model is also proved. The optimality system is derived and then solved numerically using a competitive Gauss-Seidel-like implicit difference method.

2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Abderrahim Labzai ◽  
Omar Balatif ◽  
Mostafa Rachik

The aim of this paper is to study and investigate the optimal control strategy of a discrete mathematical model of smoking with specific saturated incidence rate. The population that we are going to study is divided into five compartments: potential smokers, light smokers, heavy smokers, temporary quitters of smoking, and permanent quitters of smoking. Our objective is to find the best strategy to reduce the number of light smokers, heavy smokers, and temporary quitters of smoking. We use three control strategies which are awareness programs through media and education, treatment, and psychological support with follow-up. Pontryagins maximum principle in discrete time is used to characterize the optimal controls. The numerical simulation is carried out using MATLAB. Consequently, the obtained results confirm the performance of the optimization strategy.


2021 ◽  
Vol 46 (4) ◽  
Author(s):  
Muhammad Ozair ◽  
Takasar Hussain ◽  
Kashif Ali Abro ◽  
Sajid Jameel ◽  
Aziz Ullah Awan

2014 ◽  
Vol 25 (6) ◽  
pp. 681-705 ◽  
Author(s):  
G. W. EVATT ◽  
P. V. JOHNSON ◽  
P. W. DUCK ◽  
S. D. HOWELL

This paper considers the role of costless decisions relating to the extraction of a non-renewable resource in the presence of uncertainty. We begin by deriving a size scale of the extractable resource, above which the solution to the valuation and optimal control strategy can be described by analytic solutions; we produce solutions for a general form of operating cost function. Below this critical resource size level the valuation and optimal control strategy must be solved by numerical means; we present a robust numerical algorithm that can solve such a class of problem. We also allow for the embedding of an irreversible investment decision (abandonment) into the optimisation. Finally, we conduct experimentation for each of these two approaches (analytical and numerical), and show how they are consistent with one another when used appropriately. The extensions of this paper's techniques to renewable resources are explored.


Author(s):  
Barathram Ramkumar ◽  
D. Subbaram Naidu

Cancer chemotherapy is the treatment of cancer using drugs that kill the cancer cells, when the drugs are administered either orally or through veins. The drugs are delivered according to a schedule so that a particular dosage of drug level is maintained in the body. The disadvantage of these drugs is that they not only kill the cancer cells but also kill the normal healthy cells. The role of optimal control in chemotherapy is to maintain an optimum amount of drug level in the body so that only cancer cells are killed and hence the effect of drug on the healthy cells is minimized. Three different mathematical models for cancer growth are considered: log-kill hypothesis, Norton-simon model, and Emax model. Two different cost functions are considered for constrained and unconstrained optimal control, respectively. An open loop optimal control strategy has been reported in the literature. In this paper, a closed-loop optimal control strategy is addressed using all the three models and for both the cases of constrained and unconstrained drug delivery. For the unconstrained case the original nonlinear model has been linearized and the closed loop design is obtained by using matrix Riccati solutions. On the other hand, for the constrained case the original nonlinear model has been used to obtain closed loop optimal control using bang-bang strategy. Final simulation results show the advantages of closed loop implementation in terms of simpler and elegant controller design and incorporating the effect of current state variations.


2010 ◽  
Vol 15 (3) ◽  
pp. 299-306 ◽  
Author(s):  
A. Kaddar

We formulate a delayed SIR epidemic model by introducing a latent period into susceptible, and infectious individuals in incidence rate. This new reformulation provides a reasonable role of incubation period on the dynamics of SIR epidemic model. We show that if the basic reproduction number, denoted, R0, is less than unity, the diseasefree equilibrium is locally asymptotically stable. Moreover, we prove that if R0 > 1, the endemic equilibrium is locally asymptotically stable. In the end some numerical simulations are given to compare our model with existing model.


2012 ◽  
Vol 17 (4) ◽  
pp. 448-459 ◽  
Author(s):  
Hassan Laarabi ◽  
El Houssine Labriji ◽  
Mostafa Rachik ◽  
Abdelilah Kaddar

In this study we consider a mathematical model of an SIR epidemic model with a saturated incidence rate. We used the optimal vaccination strategies to minimize the susceptible and infected individuals and to maximize the number of recovered individuals. We work in the nonlinear optimal control framework. The existence result was discussed. A characterization of the optimal control via adjoint variables was established. We obtained an optimality system that we sought to solve numerically by a competitive Gauss–Seidel like implicit difference method.


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