scholarly journals Sequential MR Images and Radiographs of Epiphyseal Osteomyelitis in the Distal Femur of an Infant

2013 ◽  
Vol 2013 ◽  
pp. 1-4
Author(s):  
Hitomi Hara ◽  
Toshihiro Akisue ◽  
Teruya Kawamoto ◽  
Masahiro Kurosaka

Magnetic resonance imaging (MRI) plays an important role in the diagnosis of osteomyelitis, especially during the early phase of the disease. The findings of sequential MRIs during the course of treatment in acute osteomyelitis in children have not yet been reported in the literature. We present a case of acute epiphyseal osteomyelitis in the distal femur of an infant. We monitored imaging changes by sequential MRIs and radiographs. MRI was more useful than radiograph for early diagnosis and evaluation of therapeutic response.

Author(s):  
Wael Hamza Kamr ◽  
Mohamed Gaber Eissawy ◽  
Amr Saadawy

Abstract Background Early diagnosis of meningitis with magnetic resonance imaging (MRI) would be useful for appropriate and effective management, decrease morbidity and mortality, and provide better diagnosis and treatment. The objective of the current study is to compare the accuracy of contrast-enhanced FLAIR (CE-FLAIR) and contrast-enhanced T1WI (CE-T1WI) in the detection of meningeal abnormalities in suspected cases of meningitis. Results Out of 45 patients, 37 patients were confirmed to have meningitis on CSF analysis. Out of the 37 patients, 34 patients were positive on CE-FLAIR sequence and 27 were positive on CE-T1WI. The sensitivity of CE-FLAIR sequence was 91.9% and specificity 100%, while the sensitivity of CE-T1WI sequence was 73% and specificity 100%. Conclusion CE-FLAIR is more sensitive than CE-T1WI in diagnosis of meningitis. It is recommended to be used in any cases with clinically suspected meningitis.


1989 ◽  
Vol 101 (3) ◽  
pp. 295-301 ◽  
Author(s):  
Donald G. Wortham ◽  
Louis M. Teresi ◽  
Robert B. Lufkin ◽  
William N. Hanafee ◽  
Paul H. Ward

Magnetic resonance imaging (MRI) of the facial nerve was evaluated by studying normal volunteers and patients with diseases of the facial nerve with a 0.3 Tesla permanent-magnet MRI system with special surface colls. The normal MR images were correlated with the anatomy of thin cryosection specimens of fresh cadavers. The seventh nerve was followed from its nucleus in the brainstem through the temporal bone to the parotid gland bed. The entire labyrinth and tympanic portions, as well as the geniculate ganglion, could be shown with appropriate scan planes. Examples of brainstem diseases affecting the facial nerve and nucleus, facial neuromas, parotid tumors involving the facial nerve, and other diseases were studied. MRI is a technique that allows unique evaluation of the entire course of the facial nerve. It produces superior Images of the facial nerve with high-contrast resolution. Unlike computed tomography, there is no beam-hardening artifact from the temporal bone or exposure to ionizing radiation and contrast agents. MRI also allows visualization of the main trunks of the facial nerve in the parotid bed not possible with any other imaging technique.


2019 ◽  
Vol 8 (3) ◽  
pp. 127-130
Author(s):  
Salma Haji

Background: Tuberculous meningitis (TBM) is difficult to diagnose in early stages due to nonspecific symptoms. There should be high index of suspicion to diagnose TBM at an early stage. The objective of the study was to find out the role of magnetic resonance imaging (MRI) and spinal tap in early diagnosis of tuberculous meningitis. Material and Methods: A cross sectional study was conducted from July 2015 till July 2018 at Neuromedicine ward, Jinnah Postgraduate Medical Centre (JPMC), Karachi. All patients above 12 year of age, both male and female with nonspecific symptoms like headache, malaise and drowsiness or suspicion of TBM (stage I, II, and III according to British Medical Research Council TBM staging criteria) were included in the study. Patients diagnosed with other CNS disease like encephalitis, malaria and acute bacterial meningitis were excluded. Magnetic Resonance Imaging (MRI) of the brain and early spinal tap for cerebrospinal fluid (CSF) analysis were used to diagnose TBM and findings were noted. Results of MRI and CSF analysis were analyzed by SPSS version 24. Results: A total of 110 patients of TBM, with 60 (54.5%) male and 50 (45.5%) female patients were included in the study. Most of the patients belonged to a younger age group of 12-40 years (81.8%), while 18.2% were above 40 years of age. About 90% patients were diagnosed in stage I TBM and 10% in stage II and III. MRI brain findings included meningeal enhancement (60%), hydrocephalus (41.81%) cerebral edema (82.73%), tuberculoma (19%) and infarct (14.5%), respectively. CSF analysis showed low protein in 80%, low glucose in 91.8% and lymphocytic pleocytosis in 97.2%, respectively. Conclusion: Both MRI brain and spinal tap with CSF analysis played a role in the early diagnosis of TBM, which is important to prevent the lethal complications associated with late diagnosis of this disease.


Kanzo ◽  
1996 ◽  
Vol 37 (3) ◽  
pp. 170-175
Author(s):  
Naoaki KUWAHARA ◽  
Toshihiro HIGASHI ◽  
Masako TANABE ◽  
Akiko FUJIWARA ◽  
Takeshi MINATO ◽  
...  

Blood ◽  
1997 ◽  
Vol 89 (1) ◽  
pp. 286-290 ◽  
Author(s):  
Saburo Tsunoda ◽  
Shojiro Takagi ◽  
Osamu Tanaka ◽  
Yasusada Miura

Abstract We evaluated 56 consecutive patients with newly diagnosed lymphoma including 48 with non-Hodgkin's lymphoma (NHL) and 8 with Hodgkin's disease to determine the clinical and prognostic significance of magnetic resonance imaging (MRI) of the femoral marrow. MR images of the femoral marrow were obtained by the T1-weighted spin echo method and the short TI inversion recovery technique. Abnormal “positive” images were seen in 29 of the 56 patients (52%). All 17 patients with positive biopsy results showed abnormal images on their femoral marrow MRI. Three “positive” MRI patterns — scattered (72%), uniform (21%), and nodular (7%) — were observed. The overall survival of the patients with a positive MRI pattern was significantly poorer than that of patients with a normal pattern (P = .0129). Survival did not differ significantly according to MRI pattern. The 3-year survival rate in the patients with a normal MRI pattern was 89.9% and in the patients with a positive MRI pattern, it was 41.0%. This difference was statistically significant (P = .0279) when we evaluated only the patients with NHL. Patients with positive MRI patterns, but a normal bone marrow histology, showed a significantly shorter survival than those with a normal MRI pattern (P = .016). These results indicate that abnormal MR images of the femoral marrow are associated with a significantly poorer survival in patients with malignant lymphoma, regardless of histologic findings in the marrow.


2012 ◽  
Vol 25 (2) ◽  
pp. 177-181 ◽  
Author(s):  
Helen F.K. Chiu ◽  
Henry Brodaty

Impressive developments in the biomarker diagnosis of Alzheimer's disease (AD and pre-symptomatic states, using cerebrospinal fluid (CSF), positron emission tomography (PET), magnetic resonance imaging (MRI), and proteomics, have been at the forefront of research in the last decade. With the publication of the criteria of Dubois et al. (2007) and the revised National Institute on Aging and Alzheimer's Association (NIA–AA) criteria for the diagnosis of AD (Jack et al., 2011), this has further ignited the interest and enthusiasm for researchers and clinicians in the field. In some of the major conferences on dementia in recent years, the topic of the biomarker-driven diagnosis of AD has dominated the research agenda. But many questions arise as to how this research will translate into practice. Here, we would like to put forward our arguments against a biomarker-driven diagnosis of AD, and we would caution that very early diagnosis of AD may not result in better care of the subjects.


Author(s):  
Karen Chang Yan ◽  
Mary Kate McDonough ◽  
James J. Pilla ◽  
Chun Xu

Heart disease is the number one cause of death in the United States [1]. Cardiac Magnetic Resonance Imaging (MRI) technology can be used to diagnose and evaluate a number of diseases and conditions such as coronary artery disease, damage caused by a heart attack, heart failure, and heart valve problems etc. Given the inherent difficulty in imaging the heart in motion, many efforts have been made to improve cardiac motion tracking and eliminate motion related artifacts. A dynamic heart phantom (DHP) capable of simulating true physiological motions is a valuable research tool for improving quality of MR images and determining critical diagnostic information. For instance, MR images have been used to quantify myocardial strain and estimate soft tissue material parameters and in turn to learn about cardiac structure and function [2–4]. In these studies, heart phantoms made of rubber like materials with known material properties are often used as a mean of validation.


2015 ◽  
Vol 9 (1) ◽  
Author(s):  
Longquan Chen ◽  
Torben Paetz ◽  
Volker Dicken ◽  
Scheherazade Krass ◽  
Jumana Al Issawi ◽  
...  

In order to improve the current clinical application of magnetic resonance (MR)-guided prostate biopsies, a new, fully magnetic resonance imaging (MRI)-compatible solution has been developed. This solution consists of a five degree-of-freedom (5DOF) pneumatic robot, a programmable logic controller (PLC), and a software application for visualization and robot control. The robot can be freely positioned on the MR table. For the calibration of the robot and MR coordinate system, the robot’s needle guide (NG) is used. The software application supports the calibration with image segmentation and graphic overlays and guides the user through the interventional planning process. After selecting a target point, the application calculates the needed movements via solving the kinematics of the robot and translating the adjustment into commands for the PLC driving the step motors of the robot. In case further adjustments are required, the software also allows for manual control of the robot, to position the NG according to the acquired MR images.


1990 ◽  
Vol 112 (1) ◽  
pp. 93-99 ◽  
Author(s):  
Ding-Yu Fei ◽  
Kenneth A. Kraft ◽  
Panos P. Fatouros

A bolus-tracking magnetic resonance imaging (MRI) method has been employed to measure velocity profiles for oscillatory flow with and without a steady flow component as well as pulsatile flow in an axisymmetric tube model. A range of flow conditions within normal physiological limits was tested. The imaged velocity profiles were observed to be generally in accord with theoretical predictions. Instantaneous flow rates calculated from the MR images agreed well with those assessed using an ultrasonic flowmeter. Because MRI is noninvasive and poses few risks to subjects, this technique is potentially useful for studying vascular hemodynamics in vivo.


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