scholarly journals Preparation of AgI/Silica/Poly(Ethylene Glycol) Nanoparticle Colloid Solution and X-Ray Imaging Using It

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Yoshio Kobayashi ◽  
Tetsuya Ayame ◽  
Tomohiko Nakagawa ◽  
Yohsuke Kubota ◽  
Kohsuke Gonda ◽  
...  

This work performed X-ray imaging of mouse by using aqueous colloid solution of AgI nanoparticles coated with silica (AgI/SiO2) and then surface-modified with poly(ethylene glycol) (PEG) (AgI/SiO2/PEG). A colloid solution of AgI nanoparticles was prepared by mixing silver perchlorate and potassium iodide in water. The AgI nanoparticles were surface-modified with 3-mercaptopropyltrimethoxysilane and then were silica-coated by a sol-gel reaction between tetraethylorthosilicate and H2O catalyzed with NaOH in ethanol. The AgI/SiO2 particle surface was modified with PEG by using methoxy PEG silane CH3OCH2CH2OnCH2CONHC3H6SiOC2H53. The AgI/SiO2/PEG colloid solution revealed a computed tomography value as high as 1343.6 HU at an iodine concentration of 0.1 M, which was higher than a commercial X-ray contrast agent with the same iodine concentration. Tissues of mouse could be imaged by injecting the concentrated colloid solution into them.

2013 ◽  
Vol 17 (7) ◽  
pp. 507-514 ◽  
Author(s):  
Y. Kobayashi ◽  
H. Inose ◽  
R. Nagasu ◽  
T. Nakagawa ◽  
Y. Kubota ◽  
...  

2012 ◽  
Vol 1 (2) ◽  
pp. 127-130 ◽  
Author(s):  
Yoshio Kobayashi ◽  
Tetsuya Ayame ◽  
Tomohiko Nakagawa ◽  
Kohsuke Gonda ◽  
Noriaki Ohuchi

2015 ◽  
Vol 1 (2) ◽  
pp. 83-88 ◽  
Author(s):  
Yoshio Kobayashi ◽  
Ryoko Nagasu ◽  
Tomohiko Nakagawa ◽  
Yohsuke Kubota ◽  
Kohsuke Gonda ◽  
...  

2010 ◽  
Vol 16 (6) ◽  
pp. 1597-1600 ◽  
Author(s):  
Eric M. Brey ◽  
Alyssa Appel ◽  
Yu-Chieh Chiu ◽  
Zhong Zhong ◽  
Ming-Huei Cheng ◽  
...  

2013 ◽  
Vol 30 (8) ◽  
pp. 2023-2035 ◽  
Author(s):  
François Hallouard ◽  
Stéphanie Briançon ◽  
Nicolas Anton ◽  
Xiang Li ◽  
Thierry Vandamme ◽  
...  

2015 ◽  
Vol 3 (7) ◽  
pp. 1379-1390 ◽  
Author(s):  
Ailing Li ◽  
Hong Shen ◽  
Huihui Ren ◽  
Chen Wang ◽  
Decheng Wu ◽  
...  

New sol–gel functionalized poly-ethylene glycol (PEGM)/SiO2–CaO hybrids were prepared with interpenetrating networks of silica and PEGM through the formation of Si–O–Si bonds.


2003 ◽  
Vol 788 ◽  
Author(s):  
Yuki Kobayashi ◽  
Kazuki Nakanishi ◽  
Kazuyuki Hirao

ABSTRACTFormation of hierarchical macropores and mesopores in ethylene-bridged polysilsesquioxane sol-gel systems via concurrent sol-gel transition and phase separation induced by the incorporation of supramolecular templats has been investigated. A series of poly(ethylene-glycol)-poly(propyleneglycol)- poly(ethyleneglycol) triblock copolymers, EOPOEOs, have been employed as supramolecular templates, while 1,2-bis(trimethoxysilyl)ethane was used as a polysilsesquioxane source. Successful combination of templated mesopores and well-defined macropores due to phase-separation has been found in the system with EOPOEOs having 70 PO units and respective 20 EO units. Although similar macroporous morphology has been obtained for all the EOPOEOs with EO chain longer or shorter than 20 units, the optimum composition for the co-continuous macropores and that for templated mesopores deviated from each other, resulting in the failure of producing hierarchical macropores and mesopores.


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