scholarly journals Fundal Height Growth Curve for Underweight and Overweight and Obese Pregnant Women in Thai Population

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Jirawan Deeluea ◽  
Supatra Sirichotiyakul ◽  
Sawaek Weerakiet ◽  
Rajin Arora ◽  
Jayanton Patumanond
Keyword(s):  
Pregnant Women ◽  
Growth Curve ◽  
Gestational Age ◽  
Multilevel Models ◽  
Growth Curves ◽  
Height Growth ◽  
Normal Weight ◽  
Thai Population ◽  
Intrauterine Growth ◽  
Prepregnancy Weight

Objectives. To develop fundal height growth curves for underweight and overweight and obese pregnant women based on gestational age from last menstrual period and/or ultrasound. Methods. A retrospective study was conducted at four hospitals in the northern part of Thailand between January 2009 and March 2011. Fundal height, gestational age, height, and prepregnancy weight were extracted from antenatal care and delivery records. Fundal height growth curves were presented as smoothed function of the 10th, 50th, and 90th percentiles between 20 and 40 weeks of gestation, derived from multilevel models. Results. Fundal height growth curve of the underweight was derived from 1,486 measurements (208 women) and the overweight and obese curve was derived from 1,281 measurements (169 women). The 50th percentile line of the underweight was 0.1–0.4 cm below the normal weight at weeks 23–31 and 0.5–0.8 cm at weeks 32–40. The overweight and obese line was 0.1–0.4 cm above the normal weight at weeks 22–29 and 0.6–0.8 cm at weeks 30–40. Conclusions. Fundal height growth curves of the underweight and overweight and obese pregnant women were different from the normal weight. In monitoring or screening for abnormal intrauterine growth in these women, fundal height growth curves specifically developed for such women should be applied.

scholarly journals Growth in achondroplasia, from birth to adulthood, analysed by the JPA-2 model

2020 ◽  
Vol 33 (12) ◽  
pp. 1589-1595
Author(s):  
Mariana del Pino ◽  
Virginia Fano ◽  
Paula Adamo
Keyword(s):  
General Population ◽  
Growth Curve ◽  
Growth Velocity ◽  
Adult Height ◽  
Growth Curves ◽  
Peak Height ◽  
Height Growth ◽  
Individual Growth ◽  
Height Velocity ◽  
Peak Height Velocity

AbstractObjectivesIn general population, there are three phases in the human growth curve: infancy, childhood and puberty, with different main factors involved in their regulation and mathematical models to fit them. Achondroplasia children experience a fast decreasing growth during infancy and an “adolescent growth spurt”; however, there are no longitudinal studies that cover the analysis of the whole post-natal growth. Here we analyse the whole growth curve from infancy to adulthood applying the JPA-2 mathematical model.MethodsTwenty-seven patients, 17 girls and 10 boys with achondroplasia, who reached adult size, were included. Height growth data was collected from birth until adulthood. Individual growth curves were estimated by fitting the JPA-2 model to each individual’s height for age data.ResultsHeight growth velocity curves show that after a period of fast decreasing growth velocity since birth, with a mean of 9.7 cm/year at 1 year old, the growth velocity is stable in late preschool years, with a mean of 4.2 cm/year. In boys, age and peak height velocity in puberty were 13.75 years and 5.08 cm/year and reach a mean adult height of 130.52 cm. In girls, the age and peak height velocity in puberty were 11.1 years and 4.32 cm/year and reach a mean adult height of 119.2 cm.ConclusionsThe study of individual growth curves in achondroplasia children by the JPA-2 model shows the three periods, infancy, childhood and puberty, with a similar shape but lesser in magnitude than general population.

scholarly journals Fish Oil Supplementation in Pregnancy Increases Gestational Age, Size for Gestational Age, and Birth Weight in Infants: A Randomized Controlled Trial

2018 ◽  
Vol 149 (4) ◽  
pp. 628-634 ◽  
Author(s):  
Rebecca Kofod Vinding ◽  
Jakob Stokholm ◽  
Astrid Sevelsted ◽  
Bo L Chawes ◽  
Klaus Bønnelykke ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Birth Weight ◽  
Pregnant Women ◽  
Gestational Age ◽  
Controlled Trial ◽  
Growth Curves ◽  
Vitamin D Supplementation ◽  
Double Blind ◽  
Randomized Controlled ◽  
In Pregnancy

ABSTRACT Background Randomized trials have reported that supplementation with n–3 long-chain polyunsaturated fatty acids (LCPUFAs) in pregnancy can prolong pregnancy and thereby increase birth weight. Objective We aimed to examine the relations of n–3 LCPUFA supplementation in pregnancy with duration of pregnancy, birth weight, and size for gestational age (GA). Methods This was a double-blind randomized controlled trial conducted in 736 pregnant women and their offspring, from the Copenhagen Prospective Studies on Asthma in Childhood2010cohort. They were recruited between weeks 22 and 26 in pregnancy and randomly assigned to either of 2.4 g n–3 LCPUFA or control (olive oil) daily until 1 wk after birth. Exclusion criteria were endocrine, cardiovascular, or nephrologic disorders and vitamin D supplementation intake >600 IU/d. In this study we analyzed secondary outcomes, and further excluded twin pregnancies and extrauterine death. The primary outcome for the trial was persistent wheeze or asthma. Results The random assignment ran between 2008 and 2010. Six hundred and ninety-nine mother-infant pairs were included in the analysis. n–3 LCPUFA compared with control was associated with a 2-d prolongation of pregnancy [median (IQR): 282 (275–288) d compared with 280 (273–286) d, P = 0.02], a 97-g higher birth weight (mean ± SD: 3601 ± 534 g compared with 3504 ± 528 g, P = 0.02), and an increased size for GA according to the Norwegian population-based growth curves-Skjærven (mean ± SD: 49.9 ± 28.3 percentiles compared with 44.5 ± 27.6 percentiles, P = 0.01). Conclusion Supplementing pregnant women with n–3 LCPUFAs during the third trimester is associated with prolonged gestation and increased size for GA, leading to a higher birth weight in this randomized controlled trial. This trial was registered at clinicaltrials.gov as NCT00798226.

scholarly journals Gestational Age Specific Postnatal Growth Curves for Singleton Babies in Tertiary Hospital of Western Nepal

2017 ◽  
Vol 56 (207) ◽  
pp. 325-330
Author(s):  
Santosh Pathak ◽  
Nagendra Chaudhary ◽  
Prativa Dhakal ◽  
Shyam Kumar Mahato ◽  
Sandeep Shrestha ◽  
...  
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Economic Status ◽  
Tertiary Care ◽  
Growth Curves ◽  
Tertiary Hospital ◽  
Care Hospital ◽  
Cross Sectional ◽  
Intrauterine Growth ◽  
Geographical Regions

Introduction: Measurement of birth weight (BW), crown heel length (CHL), head circumference (HC) and chest circumference used to assess the intrauterine growth of a baby vary with altitude, race, gender, socio economic status, maternal size, and maternal diseases. The study aimed to construct centile charts for BW, CHL and HC for new born at different gestational ages in western Nepal. Methods:  This was a descriptive cross sectional study done over a period of 15 months in a tertiary care hospital of western Nepal. BW, length, HC and CC were measured within 12-24 hours of birth. Gestational age was estimated from first day of last menstrual period, maternal ultrasonology and New Ballard’s scoring system. Microsoft 2007 Excel and SPSS-16 was used for data analysis. Cole’s Lambda Mu Sigma method was used for constructing centile curves. Results: Out of 2000 babies analysed, 1910 samples were used to construct smoothed intrauterine growth curve of BW, CHL, and HC from 33-42 weeks of gestation. 57.35% (1147) were male, mean gestational age was 38.13 ±2.44 weeks, where 21.5% were preterm and 1.7% post term. The means of BW, CHL, HC and CC were 2744.78 gm, 47.80 cm, 33.18 cm, and 30.20 cm with standard deviations of 528.29, 3.124, 1.78, and 2.35 respectively. These data vary as compared to the Kathmandu data, in case of birth weight for 10th and 90th centiles, and at 90th centile in case of length. Conclusions: This necessitates the update in the existing growth charts and develop in different geographical regions of a country.

scholarly journals Maternal Serum Copeptin As a Biomarker For Intrauterine Growth Restriction

2021 ◽  
Vol 4 (2) ◽  
Author(s):  
Amber Hassan ◽  
Hisham Nasief
Keyword(s):  
Pregnant Women ◽  
Gestational Age ◽  
Intrauterine Growth Restriction ◽  
Maternal Serum ◽  
Growth Restriction ◽  
Cross Sectional ◽  
Intrauterine Growth ◽  
Gestation Age ◽  
Clinical Biomarker ◽  
Estimated Fetal Weight

In obstetrical world, Intrauterine Growth Restriction (IUGR) occupies second slot as a cause of small for gestation neonates, first being premature birth, both of which result in potential neonatal morbidities and mortalities. IUGR is defined as an estimated fetal weight at one point in time at or below 10th percentile for gestational age. Annually about thirty million babies suffer from IUGR and out of these about 75% are Asians. IUGR has been found to be associated with increased levels of Copeptin. As copeptin is a marker of endogenous stress, so increased copeptin levels can indicate fetal and maternal stress in IUGR Objectives: The objectives of this study were to the compare maternal serum copeptin levels in pregnancies with IUGR and pregnancies with adequate for gestational age fetuses and to establish the significance of copeptin as a biomarker for IUGR. Methodology: It was a cross-sectional comparative study in which maternal serum copeptin levels were measured and compared in 60 patients divided in two groups, pregnancies with IUGR and normal pregnancies with adequate for gestation age fetuses between 28-35 weeks of gestation Results: Maternal serum copeptin levels were raised in pregnant women with IUGR as compared to that in pregnant women with adequate for gestational age fetuses. Mean ± SD maternal serum copeptin levels were 97.5 ± 6 pg/ml in pregnant women with AGA fetuses and 121 ± 7.8 pg/ml in pregnant women with IUGR.  Conclusions: Maternal serum copeptin levels are raised in pregnancies with IUGR as compared to pregnancies with adequate for age fetuses which can represent as a possible clinical biomarker for identification of IUGR.

Comparison of the Causes and Consequences of Prematurity and Intrauterine Growth Retardation: A Longitudinal Study in Southern Brazil

PEDIATRICS ◽  
1992 ◽  
Vol 90 (2) ◽  
pp. 238-244
Author(s):  
Fernando C. Barros ◽  
Sharon R.A. Huttly ◽  
Cesar C. Victora ◽  
Betty R. Kirkwood ◽  
J. Patrick Vaughan
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Growth Retardation ◽  
Intrauterine Growth Retardation ◽  
Southern Brazil ◽  
Sources Of Information ◽  
Preterm Children ◽  
Intrauterine Growth ◽  
Prepregnancy Weight ◽  
Catch Up

A cohort of 5914 liveborns (99% of the city births) was followed up to the age of 4 years in Pelotas, southern Brazil. Besides the perinatal evaluation, the cohort children were examined again at mean ages of 11, 23, and 47 months. During each visit the children were weighed and measured and information on morbidity was collected. Also, multiple sources of information were used for monitoring mortality throughout the study. Of the babies with known gestational age, 9.0% were classified as intrauterine growth-retarded and 6.3% as preterm. Excluding those of unknown gestational age, 62% of low birth weight babies were intrauterine growth-retarded and 36% were preterm. Intrauterine growth retardation was statistically associated with maternal height, prepregnancy weight birth interval, and smoking, whereas preterm births were associated with maternal prepregnancy weight and maternal age. Preterm babies had a perinatal mortality rate 13 times higher than that of babies of appropriate birth weight and gestational age and 2 times higher than that of intrauterine growth-retarded babies. Infant mortality rates presented a similar pattern, with the differentials being more pronounced during the neonatal than in the postneonatal period. In the first 2 years of life intrauterine growth-retarded children were at almost twice the risk of being hospitalized for diarrhea compared with appropriate birth weight, term children, while preterm children experienced only a slightly greater risk. For pneumonia, however, both groups of children were hospitalized significantly more than appropriate birth weight, term children. In terms of growth, despite their earlier disadvantage, preterm children gradually caught up with their appropriate birth weight, term counterparts. This catch-up occurred primarily between mean ages 23 and 47 months. Intrauterine growth-retarded children, however, exhibited no such catch-up. Indeed, their average monthly growth rates between measurements were always lower than those of children in the other two groups.

scholarly journals Blood Ferritin Levels in Pregnant Women and Prediction of the Development of Fetal Intrauterine Growth Restriction

2011 ◽  
Vol 30 (4) ◽  
pp. 317-322
Author(s):  
Nemanja Višnjevac ◽  
Ljiljana Segedi ◽  
Aleksandar Ćurčić ◽  
Jovana Višnjevac ◽  
Dragan Stajić
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Pregnant Women ◽  
Gestational Age ◽  
Intrauterine Growth Restriction ◽  
Ferritin Level ◽  
Newborn Infants ◽  
Maternal Blood ◽  
Growth Restriction ◽  
Intrauterine Growth

Blood Ferritin Levels in Pregnant Women and Prediction of the Development of Fetal Intrauterine Growth RestrictionIntrauterine growth restriction is one of the leading causes of perinatal morbidity and mortality. Prediction of intrauterine growth restriction is one of the priority tasks of perinatal protection. The purpose of this study was to evaluate the levels of serum ferritin in pregnant women, which could point to a group of patients in whom possible development of fetal growth restriction could have been expected. In this investigation, we conducted a prospective study of healthy pregnant women between 30 and 32 gestational weeks, who were estimated for ferritin values. Newborn infants of low birth weight for gestational age were recorded in 8.1%. Anemia was not present in any of the patients who delivered low birth weight babies. Ferritin serum levels in mothers of the babies with low birth weight were on average 6.42 μg/L higher than in the mothers with appropriate for gestational age babies (p<0.005). ROC analysis of newborn infants birth weight and maternal blood ferritin levels showed that blood ferritin level had good predictive value. In case the recorded maternal blood ferritin values are above 13.6 μg/L, we can assume with the sensitivity of 64.7% and specificity of 91.7%, that the pregnant woman will develop a condition of intrauterine growth restriction. The missing decrease of ferritin values, erythrocytes, hemoglobin and hematocrit in the blood of healthy pregnant women between 30 and 32 gestational weeks, can with high probability point to the development of fetal intrauterine growth restriction.

Symphysiofundal height growth curve and growth velocity in pregnant women in a Nigerian community

2009 ◽  
Vol 29 (7) ◽  
pp. 605-608
Author(s):  
L. E. Ebite ◽  
P. N. Ebeigbe ◽  
P. Igbigbi ◽  
F. C. Akpuaka
Keyword(s):  
Pregnant Women ◽  
Growth Curve ◽  
Growth Velocity ◽  
Height Growth

scholarly journals Mitochondrial content and oxidative damage in full-term placentas from SGA, LGA and AGA infants pregnant women

2021 ◽  
Author(s):  
Joel Ramírez-Emiliano ◽  
Gloria Barbosa-Sabanero ◽  
Martha Solís-Martínez ◽  
Mariana Mina-Bravo ◽  
Edgar Martínez-Escamilla Edgar A ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Pregnant Women ◽  
Gestational Age ◽  
Adenosine Triphosphatase ◽  
Large For Gestational Age ◽  
Mitochondrial Content ◽  
Intrauterine Growth ◽  
Protein Levels ◽  
Appropriate For Gestational Age ◽  
Amp Activated Protein Kinase

IntroductionThe aim was to determine the mitochondrial content, oxidative and nitrosative status in placentas from pregnant women who delivery newborns with alteration of intrauterine growth.Material and methodsPlacentas were selected because the newborns were classified as small for gestational age (SGA, lowest 10th percentile; n = 9), appropriate for gestational age (AGA; n = 9) and large for gestational age (LGA, tallest 90th percentile; n = 9). In the placenta tissue oxidative and nitrosative status, and the mitochondrial content were determined.ResultsLipid peroxidation (TBARS) levels were higher in LGA placentas compared with SGA placentas, but not compared with AGA placentas. Carbonyl levels were higher in LGA placentas compared with the AGA and SGA placentas. The 3-nitrotyrosine (3-NT)/actin ratio was higher in the SGA and LGA placentas than in AGA placentas. Moreover, AGA placentas did have higher cytochrome oxidase (COX4)/actin ratio compared with the SGA and LGA placentas. The AMP–activated protein kinase alpha (AMPK/actin ratio was significantly lower in placentas from SGA compared with the placentas from AGA and LGA. With respect to the adenosine triphosphatase (ATPase) activity, this was significantly lower in placentas from LGA compared with the placentas from AGA and SGA.ConclusionsThe placentas of LGA newborns have higher oxidized lipid and protein levels, whereas SGA and LGA placentas have higher nitrosative damage levels than the AGA placentas; the present data also suggest that the mitochondrial content is lower in SGA and LGA placentas than in AGA placentas.

Increased Knowledge of Pregnant Women about the Importance of Micro Minerals (Fe) During Pregnancy

2021 ◽  
Vol 2 (1) ◽  
pp. 1
Author(s):  
Nico Syahputra Sebayang ◽  
Iin Nopitasari ◽  
Pestaria Saragih ◽  
Alhanannasir Alhanannasir
Keyword(s):  
Body Weight ◽  
Infant Mortality ◽  
Pregnant Women ◽  
Community Service ◽  
Gestational Age ◽  
Premature Birth ◽  
Normal Weight ◽  
Service Program ◽  
Government Programs ◽  
Short Children

Micro minerals (Fe) are indispensable for every woman, especially during pregnancy. The need for micro minerals (Fe) increases with increasing gestational age. Micro minerals (Fe) are not only important for pregnant women, they are also important for babies in the womb. Deficiency of micro minerals (Fe) can increase the risk of giving birth to babies with low body weight or premature birth and even maternal and infant mortality. If the baby is born with a normal weight, but there is still the possibility of stunting (short children). The purpose of this community service is to increase the knowledge of pregnant women about the importance of consuming micro minerals (Fe) during pregnancy. Knowledge of pregnant women in Sungai Rengit Murni village about the consumption of micro minerals (Fe) can be said to be quite good, reaching 70% of the total number of pregnant women (statement of regional midwives). We hope that as a servant, with this community service program, it is hoped that the knowledge of pregnant women about the importance of consuming micro minerals (Fe) during pregnancy will increase. So that the risk that will occur to the mother and baby is reduced. In addition, the service also supports government programs in reducing maternal problems during pregnancy until delivery.

scholarly journals Fundal Height Growth Curve for Thai Women

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Jirawan Deeluea ◽  
Supatra Sirichotiyakul ◽  
Sawaek Weerakiet ◽  
Renu Buntha ◽  
Chamaiporn Tawichasri ◽  
...  
Keyword(s):  
Growth Curve ◽  
Multilevel Model ◽  
Height Growth ◽  
Quadratic Regression ◽  
Singleton Pregnancy ◽  
Maximum Increase ◽  
Thai Women ◽  
Intrauterine Growth ◽  
Time Series Study ◽  
Series Study

Objectives. To develop fundal height (FH) growth curve from normal singleton pregnancy based on last menstrual period (LMP) and/or ultrasound dating for women in the northern part of Thailand. Methods. A retrospective time-series study was conducted at four hospitals in the upper northern part of Thailand between January 2009 and March 2011. FH from 20 to 40 weeks was measured in centimeters. The FH growth curve was presented as smoothed function of the 10th, 50th, and 90th percentiles, which were derived from a regression model fitted by a multilevel model for continuous data. Results. FH growth curve was derived from 7,523 measurements of 1,038 women. Gestational age was calculated from LMP in 648 women and ultrasound in 390 women. The FH increased from 19.1 cm at 20 weeks to 35.4 cm at 40 weeks. The maximum increase of 1.0 cm/wk was observed between 20 and 32 weeks, declining to 0.7 cm/wk between 33 and 36 weeks and 0.3 cm/wk between 37 and 40 weeks. A quadratic regression equation was FH (cm)=-19.7882+2.438157 GA (wk)-0.0262178 GA2 (wk) (R-squared = 0.85). Conclusions. A demographically specific FH growth curve may be an appropriate tool for monitoring and screening abnormal intrauterine growth.

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